Experiment set7H6 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Dimethyl Sulfoxide 5 vol%

200 most important genes:

  gene name fitness t score description  
Psest_0152 -5.9 -4.1 Imidazoleglycerol-phosphate dehydratase compare
Psest_0153 -5.5 -9.2 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0279 -5.5 -5.3 methionine biosynthesis protein MetW compare
Psest_2988 -5.2 -5.1 aspartate kinase, monofunctional class compare
Psest_2590 -5.1 -2.4 3-isopropylmalate dehydratase, small subunit compare
Psest_0508 -5.1 -6.1 gamma-glutamyl phosphate reductase compare
Psest_3384 -5.1 -7.0 glutamate 5-kinase compare
Psest_2584 -4.9 -6.7 Phosphoribosylanthranilate isomerase compare
Psest_3226 -4.9 -2.3 Predicted membrane protein compare
Psest_3298 -4.9 -8.2 histidinol dehydrogenase compare
Psest_2579 -4.9 -4.8 amidophosphoribosyltransferase compare
Psest_3866 -4.8 -14.0 threonine ammonia-lyase, biosynthetic, long form compare
Psest_2589 -4.8 -11.6 3-isopropylmalate dehydrogenase compare
Psest_2578 -4.8 -12.7 O-succinylhomoserine sulfhydrylase compare
Psest_3650 -4.8 -8.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0325 -4.7 -15.5 Putative threonine efflux protein compare
Psest_3647 -4.7 -6.4 Indole-3-glycerol phosphate synthase compare
Psest_3864 -4.6 -11.2 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3648 -4.6 -6.3 anthranilate phosphoribosyltransferase compare
Psest_0280 -4.4 -12.1 homoserine O-acetyltransferase compare
Psest_2591 -4.4 -4.2 3-isopropylmalate dehydratase, large subunit compare
Psest_0326 -4.3 -15.4 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1295 -4.3 -6.6 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3818 -4.3 -5.9 endoribonuclease L-PSP, putative compare
Psest_3299 -4.2 -12.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_3159 -4.2 -7.5 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0062 -4.2 -8.0 tryptophan synthase, alpha subunit compare
Psest_0155 -4.1 -6.2 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0954 -4.0 -12.1 Fe-S oxidoreductase compare
Psest_3649 -4.0 -8.1 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0953 -3.7 -11.2 iron-sulfur cluster-binding protein compare
Psest_1686 -3.7 -6.1 fatty acid/phospholipid synthesis protein PlsX compare
Psest_1452 -3.7 -7.5 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_0687 -3.7 -9.1 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_1509 -3.6 -11.0 quinolinate synthetase complex, A subunit compare
Psest_3123 -3.6 -4.8 dihydroorotase, homodimeric type compare
Psest_1473 -3.5 -9.8 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_3810 -3.4 -2.4 orotate phosphoribosyltransferase compare
Psest_0952 -3.4 -4.6 Uncharacterized conserved protein compare
Psest_1013 -3.4 -4.0 phosphoribosylamine--glycine ligase compare
Psest_0063 -3.4 -6.8 tryptophan synthase, beta subunit compare
Psest_1474 -3.3 -4.6 phosphoribosylaminoimidazole synthetase compare
Psest_0489 -3.2 -3.1 phosphoserine phosphatase SerB compare
Psest_0718 -3.1 -5.0 nicotinate-nucleotide pyrophosphorylase compare
Psest_1037 -3.0 -3.2 acetolactate synthase, small subunit compare
Psest_1056 -3.0 -2.8 2-isopropylmalate synthase, bacterial type compare
Psest_0313 -2.9 -2.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0411 -2.8 -10.5 biotin synthetase compare
Psest_3297 -2.7 -11.6 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_0415 -2.7 -5.0 dethiobiotin synthase compare
Psest_1947 -2.6 -1.8 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_3351 -2.6 -4.8 peptide chain release factor 3 compare
Psest_3944 -2.5 -2.4 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_1772 -2.5 -5.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0413 -2.5 -7.7 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_0306 -2.5 -14.4 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_3670 -2.5 -12.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_4085 -2.3 -13.3 Biotin carboxylase compare
Psest_4084 -2.3 -13.4 oxaloacetate decarboxylase alpha subunit compare
Psest_0412 -2.1 -10.1 8-amino-7-oxononanoate synthase compare
Psest_3721 -2.0 -7.5 Malic enzyme compare
Psest_2809 -2.0 -5.2 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_2316 -2.0 -13.0 phosphoenolpyruvate synthase compare
Psest_2018 -1.9 -4.2 Uncharacterized conserved protein compare
Psest_2719 -1.9 -4.4 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_0414 -1.8 -4.9 biotin biosynthesis protein BioC compare
Psest_3998 -1.7 -4.8 glutamate--cysteine ligase compare
Psest_3092 -1.7 -2.8 ribonuclease III, bacterial compare
Psest_4086 -1.7 -7.8 Transcriptional regulator compare
Psest_2285 -1.7 -4.2 ATP-dependent protease La compare
Psest_3767 -1.7 -4.0 tyrosine recombinase XerC compare
Psest_0267 -1.6 -9.2 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_3910 -1.6 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_3697 -1.6 -1.5 Outer membrane lipoprotein carrier protein LolA. compare
Psest_0218 -1.6 -2.9 Acyl-CoA hydrolase compare
Psest_3927 -1.6 -4.3 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_0266 -1.5 -6.2 thiamine biosynthesis protein ThiS compare
Psest_1115 -1.5 -3.7 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_0536 -1.5 -3.2 thiamine-phosphate pyrophosphorylase compare
Psest_2329 -1.5 -11.3 Transcriptional regulator compare
Psest_0477 -1.5 -9.2 thiamine biosynthesis protein ThiC compare
Psest_3943 -1.5 -2.5 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0542 -1.5 -5.2 AMP nucleosidase compare
Psest_0951 -1.5 -8.4 FAD/FMN-containing dehydrogenases compare
Psest_2850 -1.5 -2.2 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_1031 -1.5 -6.4 Uncharacterized protein conserved in bacteria compare
Psest_1518 -1.4 -2.9 tRNA_Ser_CGA compare
Psest_2668 -1.4 -3.1 Lactoylglutathione lyase and related lyases compare
Psest_0442 -1.4 -5.4 ATPases of the AAA+ class compare
Psest_2104 -1.4 -2.9 IscR-regulated protein YhgI compare
Psest_3455 -1.4 -2.2 Dihaem cytochrome c. compare
Psest_0359 -1.4 -2.0 Transcriptional regulators compare
Psest_3518 -1.4 -1.4 Transcriptional regulators compare
Psest_2358 -1.4 -1.7 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_0170 -1.3 -4.9 5,10-methenyltetrahydrofolate synthetase compare
Psest_3212 -1.3 -4.3 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_4103 -1.3 -1.5 AraC-type DNA-binding domain-containing proteins compare
Psest_0450 -1.3 -6.2 Branched-chain amino acid aminotransferase (EC 2.6.1.42) (from data) compare
Psest_2643 -1.3 -1.2 Beta-glucosidase-related glycosidases compare
Psest_1804 -1.3 -2.8 Superfamily II DNA and RNA helicases compare
Psest_0521 -1.3 -7.0 lytic murein transglycosylase compare
Psest_0845 -1.3 -1.0 hypothetical protein compare
Psest_2646 -1.3 -2.5 SOS regulatory protein LexA compare
Psest_3323 -1.3 -4.1 ribonuclease, Rne/Rng family compare
Psest_1204 -1.3 -2.3 Transcriptional regulators compare
Psest_0955 -1.3 -3.5 D,L-lactate:H+ symporter (from data) compare
Psest_3960 -1.2 -1.8 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_3890 -1.2 -0.9 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_3840 -1.2 -3.2 D-lactate/glycolate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_3908 -1.2 -1.1 Cytochrome c553 compare
Psest_1582 -1.2 -3.0 Protein of unknown function (DUF3087). compare
Psest_3185 -1.2 -1.7 MoxR-like ATPases compare
Psest_1640 -1.2 -7.6 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_0094 -1.2 -1.3 Uncharacterized enzyme of phosphonate metabolism compare
Psest_2624 -1.1 -1.2 hypothetical protein compare
Psest_3768 -1.1 -3.1 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED/haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E compare
Psest_3762 -1.1 -3.6 iron donor protein CyaY compare
Psest_0740 -1.1 -1.6 Transcriptional regulator compare
Psest_3480 -1.1 -1.0 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_2855 -1.1 -2.0 Outer membrane protein and related peptidoglycan-associated (lipo)proteins compare
Psest_2088 -1.1 -2.7 Uncharacterized protein conserved in bacteria compare
Psest_3766 -1.1 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_1292 -1.1 -5.7 monothiol glutaredoxin, Grx4 family compare
Psest_3710 -1.1 -7.2 glutamate synthase small subunit family protein, proteobacterial compare
Psest_3178 -1.1 -3.0 formyltetrahydrofolate deformylase compare
Psest_0363 -1.0 -2.4 tripartite ATP-independent periplasmic transporter solute receptor, DctP family compare
Psest_2411 -1.0 -3.8 PAS domain S-box compare
Psest_2331 -1.0 -6.8 phospho-2-dehydro-3-deoxyheptonate aldolase compare
Psest_2945 -1.0 -1.7 septum site-determining protein MinC compare
Psest_2243 -1.0 -1.5 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1259 -1.0 -4.0 23S rRNA m2A2503 methyltransferase compare
Psest_4001 -1.0 -2.8 acetylornithine deacetylase (ArgE) compare
Psest_1650 -1.0 -4.6 hypothetical protein compare
Psest_2946 -1.0 -3.7 septum site-determining protein MinD compare
Psest_0867 -1.0 -1.0 hypothetical protein compare
Psest_1532 -1.0 -2.9 DNA recombination-dependent growth factor C compare
Psest_3962 -1.0 -1.2 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_4298 -0.9 -0.7 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_2923 -0.9 -2.0 hypothetical protein compare
Psest_3367 -0.9 -1.3 translation initation factor SUI1, putative, prokaryotic compare
Psest_2324 -0.9 -7.5 hypothetical protein compare
Psest_4100 -0.9 -1.7 Uncharacterized protein conserved in bacteria compare
Psest_0673 -0.9 -2.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase compare
Psest_0212 -0.9 -1.0 exodeoxyribonuclease V, gamma subunit compare
Psest_0501 -0.9 -1.6 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_1511 -0.9 -2.7 Predicted redox protein, regulator of disulfide bond formation compare
Psest_2864 -0.9 -3.5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0759 -0.9 -1.0 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT). compare
Psest_3711 -0.9 -6.4 Glutamate synthase domain 2 compare
Psest_2090 -0.9 -1.8 Protein of unknown function (DUF2970). compare
Psest_4064 -0.9 -1.9 Lactate dehydrogenase and related dehydrogenases compare
Psest_3545 -0.9 -1.9 clan AA aspartic protease, TIGR02281 family compare
Psest_2325 -0.9 -5.1 alpha-L-glutamate ligase-related protein compare
Psest_0537 -0.9 -1.1 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_3926 -0.9 -5.9 GTP-binding protein TypA/BipA compare
Psest_3692 -0.9 -1.7 Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases compare
Psest_2413 -0.9 -1.2 Periplasmic protein TonB, links inner and outer membranes compare
Psest_3377 -0.9 -1.1 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_2585 -0.8 -1.3 pseudouridylate synthase I compare
Psest_1794 -0.8 -3.3 Flagellar motor protein compare
Psest_2650 -0.8 -2.4 hypothetical protein compare
Psest_0367 -0.8 -1.0 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_3494 -0.8 -1.2 hypothetical protein compare
Psest_3101 -0.8 -6.2 L-aspartate oxidase compare
Psest_3301 -0.8 -1.6 Predicted transcriptional regulator, BolA superfamily compare
Psest_2148 -0.8 -2.0 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_1496 -0.8 -0.9 Holliday junction DNA helicase, RuvA subunit compare
Psest_2504 -0.8 -3.5 flagellar biosynthetic protein FliS compare
Psest_2645 -0.8 -3.6 Transcriptional regulator compare
Psest_1691 -0.8 -2.6 aminodeoxychorismate lyase compare
Psest_1277 -0.8 -5.3 2-isopropylmalate synthase, yeast type compare
Psest_0498 -0.8 -1.2 ribosome small subunit-dependent GTPase A compare
Psest_3535 -0.8 -1.9 hypothetical protein compare
Psest_4051 -0.8 -1.0 molybdenum-pterin binding domain compare
Psest_1421 -0.8 -1.8 Glutathione S-transferase compare
Psest_0296 -0.7 -4.3 glutathione synthetase, prokaryotic compare
Psest_1199 -0.7 -2.5 OHCU decarboxylase compare
Psest_2651 -0.7 -2.2 DNA topoisomerase I, bacterial compare
Psest_0796 -0.7 -1.8 ABC-type transport system involved in multi-copper enzyme maturation, permease component compare
Psest_2681 -0.7 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_2810 -0.7 -3.0 5'/3'-nucleotidase SurE compare
Psest_4098 -0.7 -1.5 Superfamily I DNA and RNA helicases compare
Psest_3537 -0.7 -2.8 hypothetical protein compare
Psest_4145 -0.7 -1.2 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) compare
Psest_1419 -0.7 -2.3 Transcriptional regulator compare
Psest_4191 -0.7 -0.9 Transcriptional regulator compare
Psest_3988 -0.7 -3.8 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_0515 -0.7 -2.6 rare lipoprotein A compare
Psest_4252 -0.7 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_2323 -0.7 -5.0 Uncharacterized protein conserved in archaea compare
Psest_3937 -0.7 -0.6 ATP-dependent protease HslVU, ATPase subunit compare
Psest_3343 -0.7 -2.4 Predicted periplasmic protein compare
Psest_0640 -0.7 -1.9 Uncharacterized conserved protein compare
Psest_2632 -0.7 -2.9 ribosomal protein S12 methylthiotransferase RimO compare
Psest_2349 -0.7 -2.4 urea carboxylase-associated protein 1 compare
Psest_2218 -0.7 -1.0 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit compare
Psest_0389 -0.7 -1.1 hypothetical protein compare
Psest_2663 -0.7 -3.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1909 -0.7 -1.8 Phosphohistidine phosphatase SixA compare
Psest_2520 -0.7 -1.0 Predicted SAM-dependent methyltransferase compare


Specific Phenotypes

None in this experiment

For Pseudomonas stutzeri RCH2 in stress experiments

For stress Dimethyl Sulfoxide across organisms