Experiment set7H39 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with 5-Hydroxymethylfurfural 5 mM

200 most important genes:

  gene name fitness t score description  
Psest_0152 -6.1 -4.2 Imidazoleglycerol-phosphate dehydratase compare
Psest_0279 -5.4 -5.2 methionine biosynthesis protein MetW compare
Psest_0153 -5.3 -8.1 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_3864 -5.1 -7.9 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0508 -5.1 -6.1 gamma-glutamyl phosphate reductase compare
Psest_0155 -5.1 -3.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_2590 -5.0 -2.3 3-isopropylmalate dehydratase, small subunit compare
Psest_2578 -5.0 -9.5 O-succinylhomoserine sulfhydrylase compare
Psest_3384 -4.9 -6.7 glutamate 5-kinase compare
Psest_3866 -4.9 -11.4 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3647 -4.8 -4.6 Indole-3-glycerol phosphate synthase compare
Psest_3944 -4.8 -3.3 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_2591 -4.7 -3.3 3-isopropylmalate dehydratase, large subunit compare
Psest_3650 -4.7 -5.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3299 -4.6 -8.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0280 -4.6 -10.6 homoserine O-acetyltransferase compare
Psest_3298 -4.5 -9.2 histidinol dehydrogenase compare
Psest_0062 -4.5 -5.4 tryptophan synthase, alpha subunit compare
Psest_0953 -4.5 -10.8 iron-sulfur cluster-binding protein compare
Psest_0325 -4.4 -17.2 Putative threonine efflux protein compare
Psest_2589 -4.4 -8.8 3-isopropylmalate dehydrogenase compare
Psest_3648 -4.4 -5.2 anthranilate phosphoribosyltransferase compare
Psest_1037 -4.3 -4.2 acetolactate synthase, small subunit compare
Psest_2584 -4.3 -5.1 Phosphoribosylanthranilate isomerase compare
Psest_2579 -4.2 -2.9 amidophosphoribosyltransferase compare
Psest_0952 -4.0 -2.8 Uncharacterized conserved protein compare
Psest_0954 -4.0 -8.9 Fe-S oxidoreductase compare
Psest_1452 -3.9 -7.5 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_3649 -3.9 -6.5 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0326 -3.7 -14.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1473 -3.6 -9.0 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0687 -3.4 -7.2 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0489 -3.3 -3.9 phosphoserine phosphatase SerB compare
Psest_0063 -3.2 -5.4 tryptophan synthase, beta subunit compare
Psest_1509 -3.2 -10.5 quinolinate synthetase complex, A subunit compare
Psest_3159 -3.1 -8.6 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1947 -3.1 -2.1 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1295 -3.1 -5.1 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3810 -3.0 -2.1 orotate phosphoribosyltransferase compare
Psest_3123 -2.9 -4.3 dihydroorotase, homodimeric type compare
Psest_1474 -2.9 -3.9 phosphoribosylaminoimidazole synthetase compare
Psest_0313 -2.9 -2.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3226 -2.8 -1.7 Predicted membrane protein compare
Psest_1772 -2.8 -6.0 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0718 -2.7 -4.1 nicotinate-nucleotide pyrophosphorylase compare
Psest_3297 -2.6 -11.3 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_1013 -2.5 -2.9 phosphoribosylamine--glycine ligase compare
Psest_2329 -2.4 -14.9 Transcriptional regulator compare
Psest_0346 -2.3 -3.2 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_3818 -2.3 -7.3 endoribonuclease L-PSP, putative compare
Psest_1115 -2.3 -4.3 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_3998 -2.3 -6.2 glutamate--cysteine ligase compare
Psest_2907 -2.2 -2.3 Protein of unknown function (DUF3618). compare
Psest_4310 -2.2 -1.8 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_4085 -2.1 -13.4 Biotin carboxylase compare
Psest_0411 -2.1 -9.3 biotin synthetase compare
Psest_3943 -2.0 -3.0 Phosphoribosyl-AMP cyclohydrolase compare
Psest_4084 -1.9 -12.5 oxaloacetate decarboxylase alpha subunit compare
Psest_4307 -1.8 -2.4 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_2001 -1.8 -2.2 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_0306 -1.7 -11.8 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_2325 -1.7 -8.0 alpha-L-glutamate ligase-related protein compare
Psest_1496 -1.7 -1.5 Holliday junction DNA helicase, RuvA subunit compare
Psest_3092 -1.7 -2.4 ribonuclease III, bacterial compare
Psest_0536 -1.7 -4.2 thiamine-phosphate pyrophosphorylase compare
Psest_3129 -1.7 -1.8 tyrosine recombinase XerD compare
Psest_0413 -1.7 -5.4 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_4086 -1.6 -7.8 Transcriptional regulator compare
Psest_0266 -1.6 -5.9 thiamine biosynthesis protein ThiS compare
Psest_0442 -1.5 -3.9 ATPases of the AAA+ class compare
Psest_3720 -1.5 -10.0 penicillin-binding protein, 1A family compare
Psest_0031 -1.5 -1.9 Uncharacterized conserved protein compare
Psest_0414 -1.5 -4.7 biotin biosynthesis protein BioC compare
Psest_1643 -1.5 -1.6 hypothetical protein compare
Psest_0393 -1.5 -4.9 Methylase of chemotaxis methyl-accepting proteins compare
Psest_2104 -1.5 -3.1 IscR-regulated protein YhgI compare
Psest_0412 -1.5 -8.2 8-amino-7-oxononanoate synthase compare
Psest_2945 -1.5 -2.0 septum site-determining protein MinC compare
Psest_1920 -1.5 -1.5 Uncharacterized protein conserved in bacteria compare
Psest_2324 -1.4 -9.9 hypothetical protein compare
Psest_0831 -1.4 -1.2 hypothetical protein compare
Psest_1686 -1.4 -4.5 fatty acid/phospholipid synthesis protein PlsX compare
Psest_0533 -1.4 -3.9 Sel1 repeat. compare
Psest_0951 -1.4 -7.3 FAD/FMN-containing dehydrogenases compare
Psest_2323 -1.3 -8.6 Uncharacterized protein conserved in archaea compare
Psest_2872 -1.3 -2.3 protein RecA compare
Psest_3767 -1.3 -3.9 tyrosine recombinase XerC compare
Psest_3721 -1.3 -5.1 Malic enzyme compare
Psest_2645 -1.3 -6.2 Transcriptional regulator compare
Psest_0267 -1.3 -6.6 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_0349 -1.2 -5.3 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_0415 -1.2 -3.6 dethiobiotin synthase compare
Psest_2988 -1.2 -4.8 aspartate kinase, monofunctional class compare
Psest_0359 -1.2 -1.5 Transcriptional regulators compare
Psest_0477 -1.2 -8.0 thiamine biosynthesis protein ThiC compare
Psest_3803 -1.2 -1.5 DNA repair protein radc compare
Psest_3323 -1.2 -3.0 ribonuclease, Rne/Rng family compare
Psest_2626 -1.1 -2.3 Flp pilus assembly protein CpaB compare
Psest_2768 -1.1 -2.6 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_3399 -1.1 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_2379 -1.1 -7.0 PAS domain S-box compare
Psest_3908 -1.1 -0.9 Cytochrome c553 compare
Psest_2641 -1.1 -6.7 Conserved secreted protein compare
Psest_0013 -1.1 -4.5 Lauroyl/myristoyl acyltransferase compare
Psest_2333 -1.1 -1.2 Protein of unknown function (DUF3359). compare
Psest_3354 -1.1 -3.7 1-phosphofructokinase (EC 2.7.1.56) (from data) compare
Psest_1574 -1.1 -2.5 phenazine biosynthesis protein PhzF family compare
Psest_3322 -1.1 -8.7 TIGR02099 family protein compare
Psest_2864 -1.1 -3.0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4243 -1.1 -1.1 type VI secretion lipoprotein, VC_A0113 family compare
Psest_1292 -1.0 -5.4 monothiol glutaredoxin, Grx4 family compare
Psest_4345 -1.0 -6.1 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_3937 -1.0 -1.4 ATP-dependent protease HslVU, ATPase subunit compare
Psest_0296 -1.0 -5.4 glutathione synthetase, prokaryotic compare
Psest_2911 -1.0 -2.0 Protein of unknown function (DUF2945). compare
Psest_1527 -1.0 -7.2 Na+/proline symporter compare
Psest_1640 -1.0 -7.0 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_0316 -1.0 -2.1 Cytochrome c556 compare
Psest_3862 -1.0 -7.2 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0097 -1.0 -1.1 phosphonates metabolism transcriptional regulator PhnF compare
Psest_0257 -1.0 -2.4 Predicted Zn-dependent peptidases compare
Psest_0182 -1.0 -4.4 glycine cleavage system H protein compare
Psest_1647 -0.9 -2.6 Lhr-like helicases compare
Psest_0537 -0.9 -1.5 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_1056 -0.9 -1.7 2-isopropylmalate synthase, bacterial type compare
Psest_0212 -0.9 -0.6 exodeoxyribonuclease V, gamma subunit compare
Psest_2646 -0.9 -1.6 SOS regulatory protein LexA compare
Psest_0297 -0.9 -3.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2647 -0.9 -2.3 SOS-response cell division inhibitor, blocks FtsZ ring formation compare
Psest_0347 -0.9 -6.9 large component of pyruvate/D-alanine transporter (actP-like) (from data) compare
Psest_3828 -0.9 -0.6 zinc-binding alcohol dehydrogenase family protein compare
Psest_3178 -0.9 -2.4 formyltetrahydrofolate deformylase compare
Psest_1349 -0.8 -2.2 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_3565 -0.8 -1.3 hypothetical protein compare
Psest_0501 -0.8 -1.8 Predicted nucleoside-diphosphate-sugar epimerases compare
Psest_2681 -0.8 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_2148 -0.8 -2.1 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_4211 -0.8 -2.2 conserverd hypothetical protein compare
Psest_4406 -0.8 -1.3 hypothetical protein compare
Psest_3185 -0.8 -1.3 MoxR-like ATPases compare
Psest_1532 -0.8 -2.6 DNA recombination-dependent growth factor C compare
Psest_3531 -0.8 -1.2 Peptidase propeptide and YPEB domain. compare
Psest_1118 -0.8 -2.2 Predicted Fe-S-cluster oxidoreductase compare
Psest_1424 -0.8 -1.4 Lipoate-protein ligase A compare
Psest_3546 -0.8 -0.9 Phosphatidylglycerophosphatase A and related proteins compare
Psest_0300 -0.8 -4.4 Methyl-accepting chemotaxis protein compare
Psest_1277 -0.8 -5.4 2-isopropylmalate synthase, yeast type compare
Psest_0484 -0.8 -2.3 hypothetical protein compare
Psest_0170 -0.8 -3.7 5,10-methenyltetrahydrofolate synthetase compare
Psest_2944 -0.8 -1.5 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_2946 -0.8 -2.4 septum site-determining protein MinD compare
Psest_2622 -0.8 -1.9 TadE-like protein. compare
Psest_1914 -0.8 -4.0 Predicted permeases compare
Psest_1397 -0.8 -2.2 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_3031 -0.8 -0.8 hypothetical protein compare
Psest_2448 -0.8 -1.9 AraC-type DNA-binding domain-containing proteins compare
Psest_0133 -0.7 -1.0 type VI secretion protein, VC_A0107 family compare
Psest_2411 -0.7 -2.9 PAS domain S-box compare
Psest_0355 -0.7 -1.1 Glycine cleavage system regulatory protein compare
Psest_0998 -0.7 -1.9 poly(A) polymerase compare
Psest_3527 -0.7 -2.8 Pseudouridylate synthases, 23S RNA-specific compare
Psest_1540 -0.7 -1.1 biotin-dependent carboxylase uncharacterized domain compare
Psest_2450 -0.7 -2.7 hypothetical protein compare
Psest_0516 -0.7 -4.5 D-alanyl-D-alanine carboxypeptidase compare
Psest_4044 -0.7 -2.5 type I site-specific deoxyribonuclease, HsdR family compare
Psest_1642 -0.7 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_1008 -0.7 -0.9 hypothetical protein compare
Psest_0368 -0.7 -1.1 Transcriptional regulator compare
Psest_3301 -0.7 -2.1 Predicted transcriptional regulator, BolA superfamily compare
Psest_2177 -0.7 -2.5 Protein of unknown function (DUF1652). compare
Psest_1063 -0.7 -3.7 Predicted permease, DMT superfamily compare
Psest_2419 -0.7 -2.6 AraC-type DNA-binding domain-containing proteins compare
Psest_3496 -0.7 -0.6 Predicted metal-binding protein compare
Psest_3084 -0.7 -1.6 methyltransferase, putative compare
Psest_2650 -0.7 -1.8 hypothetical protein compare
Psest_1144 -0.7 -1.3 AmpG-related permease compare
Psest_1361 -0.7 -3.1 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_1562 -0.7 -1.6 Uncharacterized protein conserved in bacteria compare
Psest_4252 -0.7 -1.8 Uncharacterized protein conserved in bacteria compare
Psest_1054 -0.7 -3.0 Diaminopimelate decarboxylase compare
Psest_0498 -0.7 -0.8 ribosome small subunit-dependent GTPase A compare
Psest_1601 -0.7 -1.4 Signal transduction histidine kinase compare
Psest_3535 -0.7 -1.3 hypothetical protein compare
Psest_0744 -0.7 -0.7 Uncharacterized conserved protein compare
Psest_2138 -0.7 -2.4 RND family efflux transporter, MFP subunit compare
Psest_0886 -0.7 -2.2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_3717 -0.7 -3.0 Tfp pilus assembly protein PilO compare
Psest_1405 -0.7 -3.5 hypothetical protein compare
Psest_0054 -0.7 -2.1 hypothetical protein compare
Psest_3286 -0.7 -2.5 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_3377 -0.7 -0.7 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_2885 -0.6 -2.0 Acyl carrier protein compare
Psest_3806 -0.6 -3.3 Phosphomannomutase compare
Psest_2370 -0.6 -0.8 Protein of unknown function (DUF1652). compare
Psest_3522 -0.6 -2.5 3-hydroxybutyrate dehydrogenase compare
Psest_2923 -0.6 -1.0 hypothetical protein compare
Psest_3955 -0.6 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_2866 -0.6 -2.5 Uncharacterized conserved protein compare
Psest_2680 -0.6 -3.1 transcriptional regulator, BolA protein family compare
Psest_4297 -0.6 -3.9 PAS domain S-box compare


Specific Phenotypes

None in this experiment

For Pseudomonas stutzeri RCH2 in stress experiments

For stress 5-Hydroxymethylfurfural across organisms