Experiment set7H33 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Nalidixic acid sodium salt 0.001 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0279 -5.7 -7.7 methionine biosynthesis protein MetW compare
Psest_0326 -4.9 -17.1 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0153 -4.8 -16.4 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0152 -4.8 -7.7 Imidazoleglycerol-phosphate dehydratase compare
Psest_3944 -4.7 -5.5 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_3648 -4.7 -7.1 anthranilate phosphoribosyltransferase compare
Psest_0155 -4.5 -9.6 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3307 -4.5 -4.4 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3866 -4.5 -19.0 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3647 -4.2 -7.5 Indole-3-glycerol phosphate synthase compare
Psest_0062 -4.2 -12.2 tryptophan synthase, alpha subunit compare
Psest_0280 -4.2 -17.7 homoserine O-acetyltransferase compare
Psest_0508 -4.1 -10.8 gamma-glutamyl phosphate reductase compare
Psest_3299 -4.0 -12.0 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_3226 -4.0 -1.7 Predicted membrane protein compare
Psest_3864 -4.0 -17.6 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3305 -3.9 -7.9 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_3650 -3.9 -12.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0466 -3.9 -5.2 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_3303 -3.7 -6.6 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0063 -3.6 -9.8 tryptophan synthase, beta subunit compare
Psest_0325 -3.6 -20.8 Putative threonine efflux protein compare
Psest_3298 -3.6 -12.1 histidinol dehydrogenase compare
Psest_2872 -3.5 -2.4 protein RecA compare
Psest_3304 -3.5 -5.8 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_0489 -3.5 -5.2 phosphoserine phosphatase SerB compare
Psest_2578 -3.5 -12.1 O-succinylhomoserine sulfhydrylase compare
Psest_2584 -3.5 -5.7 Phosphoribosylanthranilate isomerase compare
Psest_0013 -3.4 -9.2 Lauroyl/myristoyl acyltransferase compare
Psest_0687 -3.4 -10.0 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_2712 -3.4 -5.2 Surface lipoprotein compare
Psest_0952 -3.3 -3.9 Uncharacterized conserved protein compare
Psest_3384 -3.3 -11.7 glutamate 5-kinase compare
Psest_2590 -3.3 -2.0 3-isopropylmalate dehydratase, small subunit compare
Psest_3306 -3.3 -7.2 conserved hypothetical integral membrane protein compare
Psest_3810 -3.2 -3.7 orotate phosphoribosyltransferase compare
Psest_0954 -3.2 -10.0 Fe-S oxidoreductase compare
Psest_2325 -3.1 -8.4 alpha-L-glutamate ligase-related protein compare
Psest_3649 -3.1 -10.1 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0313 -3.1 -4.6 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3883 -3.0 -7.9 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2591 -2.9 -3.8 3-isopropylmalate dehydratase, large subunit compare
Psest_3943 -2.8 -3.8 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0309 -2.8 -2.8 RND family efflux transporter, MFP subunit compare
Psest_1452 -2.8 -9.8 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_0718 -2.7 -4.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_2579 -2.7 -6.5 amidophosphoribosyltransferase compare
Psest_3960 -2.7 -1.9 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_2324 -2.7 -12.9 hypothetical protein compare
Psest_1532 -2.7 -4.0 DNA recombination-dependent growth factor C compare
Psest_3767 -2.6 -6.7 tyrosine recombinase XerC compare
Psest_4191 -2.6 -3.0 Transcriptional regulator compare
Psest_0953 -2.6 -10.1 iron-sulfur cluster-binding protein compare
Psest_1509 -2.5 -8.8 quinolinate synthetase complex, A subunit compare
Psest_0310 -2.5 -3.3 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_3720 -2.5 -15.5 penicillin-binding protein, 1A family compare
Psest_0311 -2.4 -6.0 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_3535 -2.4 -3.6 hypothetical protein compare
Psest_2323 -2.3 -11.3 Uncharacterized protein conserved in archaea compare
Psest_3129 -2.3 -2.1 tyrosine recombinase XerD compare
Psest_0476 -2.2 -10.8 type I secretion outer membrane protein, TolC family compare
Psest_1474 -2.2 -4.0 phosphoribosylaminoimidazole synthetase compare
Psest_2379 -2.2 -9.3 PAS domain S-box compare
Psest_3884 -2.2 -1.3 Signal transduction histidine kinase compare
Psest_2589 -2.1 -8.6 3-isopropylmalate dehydrogenase compare
Psest_3990 -2.1 -9.2 PAP2 superfamily. compare
Psest_3766 -2.1 -3.7 Uncharacterized protein conserved in bacteria compare
Psest_0457 -2.1 -5.1 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0266 -2.1 -8.7 thiamine biosynthesis protein ThiS compare
Psest_2025 -2.1 -1.5 cold shock domain protein CspD compare
Psest_0267 -2.0 -12.9 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_1837 -2.0 -8.1 Endoglucanase compare
Psest_0536 -2.0 -6.1 thiamine-phosphate pyrophosphorylase compare
Psest_1947 -2.0 -1.9 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_2646 -2.0 -3.5 SOS regulatory protein LexA compare
Psest_1295 -2.0 -6.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0442 -2.0 -5.6 ATPases of the AAA+ class compare
Psest_1037 -2.0 -2.9 acetolactate synthase, small subunit compare
Psest_1496 -1.9 -2.2 Holliday junction DNA helicase, RuvA subunit compare
Psest_2276 -1.9 -6.3 Aldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
Psest_0393 -1.9 -7.0 Methylase of chemotaxis methyl-accepting proteins compare
Psest_0193 -1.9 -1.8 conserved hypothetical protein compare
Psest_3092 -1.9 -2.4 ribonuclease III, bacterial compare
Psest_1013 -1.8 -3.4 phosphoribosylamine--glycine ligase compare
Psest_0257 -1.8 -3.4 Predicted Zn-dependent peptidases compare
Psest_3159 -1.8 -5.8 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_3862 -1.7 -12.0 phosphoenolpyruvate-protein phosphotransferase compare
Psest_3536 -1.7 -2.1 hypothetical protein compare
Psest_1154 -1.7 -8.6 RND family efflux transporter, MFP subunit compare
Psest_0186 -1.6 -3.6 Protein-disulfide isomerase compare
Psest_3373 -1.6 -6.3 Tfp pilus assembly protein PilX compare
Psest_1473 -1.6 -6.2 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_1153 -1.6 -12.9 Cation/multidrug efflux pump compare
Psest_4345 -1.6 -8.7 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_3374 -1.6 -9.3 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_2810 -1.6 -3.8 5'/3'-nucleotidase SurE compare
Psest_3565 -1.6 -1.8 hypothetical protein compare
Psest_0477 -1.6 -10.2 thiamine biosynthesis protein ThiC compare
Psest_4219 -1.5 -3.2 DNA polymerase I compare
Psest_3464 -1.5 -6.6 Signal transduction histidine kinase compare
Psest_3480 -1.5 -1.6 molybdenum cofactor biosynthesis protein B, proteobacterial compare
Psest_2651 -1.5 -2.9 DNA topoisomerase I, bacterial compare
Psest_0537 -1.4 -2.4 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_3664 -1.4 -1.3 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_1486 -1.4 -3.3 hypothetical protein compare
Psest_4307 -1.4 -2.6 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_0485 -1.4 -4.4 clan AA aspartic protease, TIGR02281 family compare
Psest_4363 -1.3 -7.5 ATPases involved in chromosome partitioning compare
Psest_0962 -1.3 -8.2 DNA repair protein RecN conserved
Psest_3222 -1.3 -2.7 Putative threonine efflux protein compare
Psest_3401 -1.3 -5.1 DNA repair protein RadA conserved
Psest_2308 -1.3 -1.3 Predicted Fe-S protein compare
Psest_1870 -1.3 -1.6 Transcriptional regulators compare
Psest_1115 -1.3 -2.9 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_4044 -1.3 -5.3 type I site-specific deoxyribonuclease, HsdR family compare
Psest_3372 -1.2 -7.2 Tfp pilus assembly protein PilW compare
Psest_3230 -1.2 -5.6 Uncharacterized conserved protein compare
Psest_1284 -1.2 -2.7 exodeoxyribonuclease VII, large subunit compare
Psest_3716 -1.2 -7.0 Tfp pilus assembly protein PilP compare
Psest_3322 -1.2 -9.6 TIGR02099 family protein compare
Psest_4310 -1.2 -1.7 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_1840 -1.2 -9.5 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_2333 -1.1 -1.1 Protein of unknown function (DUF3359). compare
Psest_3317 -1.1 -3.9 Phosphotransferase System HPr (HPr) Family compare
Psest_0411 -1.1 -7.2 biotin synthetase compare
Psest_2944 -1.1 -1.8 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_3371 -1.1 -5.9 type IV pilus modification protein PilV compare
Psest_0814 -1.1 -1.8 MoxR-like ATPases compare
Psest_0218 -1.1 -2.8 Acyl-CoA hydrolase compare
Psest_0146 -1.1 -5.4 Uncharacterized protein involved in outer membrane biogenesis compare
Psest_2380 -1.1 -6.9 Uncharacterized conserved protein compare
Psest_3370 -1.1 -6.7 prepilin-type N-terminal cleavage/methylation domain compare
Psest_3718 -1.0 -3.3 Tfp pilus assembly protein PilN compare
Psest_0919 -1.0 -2.7 Permeases of the drug/metabolite transporter (DMT) superfamily compare
Psest_3123 -1.0 -1.9 dihydroorotase, homodimeric type compare
Psest_0300 -1.0 -5.1 Methyl-accepting chemotaxis protein compare
Psest_3155 -1.0 -2.6 hypothetical protein compare
Psest_0529 -1.0 -5.8 Putative Mg2+ and Co2+ transporter CorC compare
Psest_4098 -1.0 -2.8 Superfamily I DNA and RNA helicases compare
Psest_1049 -1.0 -3.7 Uncharacterized paraquat-inducible protein A compare
Psest_2641 -1.0 -6.0 Conserved secreted protein compare
Psest_3044 -1.0 -4.1 deoxycytidine triphosphate deaminase compare
Psest_2809 -1.0 -1.5 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_0349 -1.0 -4.9 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_2030 -1.0 -2.9 leucyl/phenylalanyl-tRNA--protein transferase compare
Psest_2667 -1.0 -2.0 Uncharacterized protein involved in propionate catabolism compare
Psest_2586 -1.0 -7.5 FimV N-terminal domain compare
Psest_1120 -1.0 -4.0 uracil phosphoribosyltransferase compare
Psest_1054 -0.9 -4.3 Diaminopimelate decarboxylase compare
Psest_2768 -0.9 -2.2 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_1184 -0.9 -2.5 Uncharacterized protein, possibly involved in utilization of glycolate and propanediol compare
Psest_0181 -0.9 -3.8 glycine cleavage system T protein compare
Psest_1597 -0.9 -2.5 Protein of unknown function (DUF2933). compare
Psest_0484 -0.9 -2.7 hypothetical protein compare
Psest_3719 -0.9 -6.2 type IV pilus assembly protein PilM compare
Psest_3148 -0.9 -1.2 hypothetical protein compare
Psest_0462 -0.9 -8.6 Lipid A core - O-antigen ligase and related enzymes compare
Psest_2405 -0.9 -1.8 NAD-dependent protein deacetylases, SIR2 family compare
Psest_1082 -0.9 -2.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_3286 -0.9 -3.6 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_3477 -0.9 -2.2 Signal transduction histidine kinase compare
Psest_1055 -0.9 -5.4 Saccharopine dehydrogenase and related proteins compare
Psest_3927 -0.9 -3.6 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_3904 -0.9 -0.6 hypothetical protein compare
Psest_1724 -0.9 -2.3 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_2243 -0.9 -1.2 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_2885 -0.9 -2.3 Acyl carrier protein compare
Psest_2177 -0.9 -2.8 Protein of unknown function (DUF1652). compare
Psest_2964 -0.9 -3.6 flagellar basal-body rod protein FlgF compare
Psest_2613 -0.9 -1.3 hypothetical protein compare
Psest_1222 -0.9 -6.1 Nucleoid-associated protein compare
Psest_0334 -0.9 -1.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0346 -0.9 -1.7 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_0575 -0.8 -0.7 HrpA-like helicases compare
Psest_1640 -0.8 -5.0 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_0955 -0.8 -2.6 D,L-lactate:H+ symporter (from data) compare
Psest_3715 -0.8 -6.5 type IV pilus secretin (or competence protein) PilQ compare
Psest_1951 -0.8 -1.1 Uncharacterized protein conserved in bacteria compare
Psest_3400 -0.8 -1.3 Copper resistance protein D. compare
Psest_0207 -0.8 -2.0 hypothetical protein compare
Psest_4163 -0.8 -2.1 hypothetical protein compare
Psest_3962 -0.8 -0.8 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_1022 -0.8 -4.6 Thiol:disulfide interchange protein compare
Psest_1179 -0.8 -1.4 2-hydroxy-3-oxopropionate reductase compare
Psest_0327 -0.8 -3.3 Transcriptional regulator compare
Psest_1940 -0.8 -2.1 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain compare
Psest_1514 -0.8 -3.3 Glycine cleavage system regulatory protein compare
Psest_3828 -0.8 -0.7 zinc-binding alcohol dehydrogenase family protein compare
Psest_2786 -0.8 -1.1 Domain of unknown function (DUF3597). compare
Psest_0707 -0.8 -4.0 MYND finger. compare
Psest_0347 -0.8 -6.2 large component of pyruvate/D-alanine transporter (actP-like) (from data) compare
Psest_0708 -0.8 -1.1 outer membrane assembly lipoprotein YfiO compare
Psest_3992 -0.8 -4.3 Uncharacterized protein conserved in archaea compare
Psest_1510 -0.8 -1.9 Putative Zn-dependent protease, contains TPR repeats compare
Psest_1636 -0.8 -2.4 putative transporter, required for glycine utilization (from data) compare
Psest_2744 -0.8 -1.1 Uncharacterized conserved protein compare
Psest_2758 -0.8 -1.7 Predicted transcriptional regulators compare
Psest_1017 -0.8 -3.8 Protein of unknown function (DUF3426). compare
Psest_3128 -0.8 -2.8 Protein-disulfide isomerase compare
Psest_0684 -0.8 -2.5 GTP-binding protein HflX compare


Specific Phenotypes

For 16 genes in this experiment

For stress Nalidixic acid sodium salt in Pseudomonas stutzeri RCH2

For stress Nalidixic acid sodium salt across organisms