Experiment set7H33 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Nalidixic acid sodium salt 0.001 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
Psest_0740 +4.9 15.5 Transcriptional regulator compare
Psest_4273 +2.4 18.2 Lysophospholipase compare
Psest_1815 +2.2 16.3 pseudaminic acid synthase compare
Psest_2950 +2.1 8.3 putative NAD(P)H quinone oxidoreductase, PIG3 family compare
Psest_1974 +2.1 6.9 integration host factor, alpha subunit compare
Psest_1986 +2.1 4.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
Psest_1292 +2.1 15.9 monothiol glutaredoxin, Grx4 family compare
Psest_1805 +2.1 8.7 integration host factor, beta subunit compare
Psest_1661 +1.9 4.8 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_0999 +1.9 6.8 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_1704 +1.8 4.8 Dehydrogenases (flavoproteins) compare
Psest_1813 +1.8 13.8 pseudaminic acid biosynthesis-associated protein PseG compare
Psest_1819 +1.8 15.9 Nucleoside-diphosphate-sugar epimerases compare
Psest_2104 +1.7 4.7 IscR-regulated protein YhgI compare
Psest_0307 +1.7 6.6 Cytochrome B561 compare
Psest_0417 +1.7 7.2 Acyl-CoA dehydrogenases compare
Psest_1657 +1.7 4.4 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_1994 +1.6 7.8 Amidases related to nicotinamidase compare
Psest_1655 +1.6 7.9 NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit compare
Psest_1659 +1.6 5.7 NADH:ubiquinone oxidoreductase, Na(+)-translocating, E subunit compare
Psest_3296 +1.5 9.6 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_2719 +1.5 7.1 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_1235 +1.5 9.9 Leucyl aminopeptidase compare
Psest_2857 +1.5 10.6 Rad3-related DNA helicases conserved
Psest_3910 +1.5 2.2 Uncharacterized protein conserved in bacteria compare
Psest_3100 +1.5 11.4 RNA polymerase sigma factor RpoE compare
Psest_3697 +1.4 1.8 Outer membrane lipoprotein carrier protein LolA. compare
Psest_2038 +1.4 11.2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2268 +1.4 7.0 Alcohol dehydrogenase, class IV compare
Psest_2288 +1.4 5.0 trigger factor compare
Psest_1656 +1.4 4.8 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_2581 +1.4 4.0 Uncharacterized protein conserved in bacteria compare
Psest_2267 +1.3 9.8 PAS domain S-box compare
Psest_2643 +1.3 2.4 Beta-glucosidase-related glycosidases compare
Psest_2285 +1.3 4.7 ATP-dependent protease La compare
Psest_0164 +1.3 1.8 Glutaredoxin, GrxC family compare
Psest_1660 +1.3 4.4 NADH:ubiquinone oxidoreductase, Na(+)-translocating, F subunit compare
Psest_0161 +1.2 3.9 Membrane-bound metallopeptidase compare
Psest_1725 +1.2 10.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4141 +1.2 7.4 3-carboxymuconate cyclase compare
Psest_1809 +1.2 8.6 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_0378 +1.2 2.8 Lactate dehydrogenase and related dehydrogenases compare
Psest_3113 +1.2 3.8 electron transport complex, RnfABCDGE type, B subunit compare
Psest_1804 +1.2 4.1 Superfamily II DNA and RNA helicases compare
Psest_0515 +1.2 5.3 rare lipoprotein A compare
Psest_0259 +1.2 2.8 cell division ATP-binding protein FtsE compare
Psest_3115 +1.1 7.7 electron transport complex, RnfABCDGE type, D subunit compare
Psest_0697 +1.1 3.7 ribosomal protein L9 compare
Psest_3936 +1.1 4.2 ATP-dependent protease HslVU, peptidase subunit compare
Psest_1016 +1.1 4.5 putative TIM-barrel protein, nifR3 family compare
Psest_0692 +1.1 4.1 rRNA methylase, putative, group 3 compare
Psest_3693 +1.1 2.4 Glycosyltransferases involved in cell wall biogenesis compare
Psest_0192 +1.1 7.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3014 +1.1 2.0 cob(I)alamin adenosyltransferase compare
Psest_2427 +1.1 6.0 SH3 domain protein compare
Psest_1000 +1.1 7.7 PAS domain S-box compare
Psest_3670 +1.1 8.4 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
Psest_0487 +1.1 5.2 Uncharacterized protein conserved in bacteria compare
Psest_1910 +1.1 3.4 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase compare
Psest_3926 +1.1 8.2 GTP-binding protein TypA/BipA compare
Psest_1824 +1.1 3.2 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_2585 +1.1 1.9 pseudouridylate synthase I compare
Psest_1505 +1.1 2.3 Organic radical activating enzymes compare
Psest_3784 +1.1 2.7 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_2229 +1.1 3.5 Uncharacterized protein conserved in bacteria compare
Psest_0227 +1.0 2.0 Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific compare
Psest_1470 +1.0 6.7 succinyldiaminopimelate transaminase compare
Psest_2088 +1.0 1.3 Uncharacterized protein conserved in bacteria compare
Psest_2764 +1.0 1.9 hypothetical protein compare
Psest_3016 +1.0 7.4 TonB-dependent vitamin B12 receptor compare
Psest_1595 +1.0 1.9 Copper chaperone compare
Psest_2130 +1.0 3.7 exodeoxyribonuclease III compare
Psest_3496 +1.0 1.6 Predicted metal-binding protein compare
Psest_1489 +1.0 3.3 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Psest_0538 +1.0 9.6 Signal transduction histidine kinase compare
Psest_3938 +1.0 2.9 Uncharacterized protein conserved in bacteria compare
Psest_0464 +1.0 8.8 Mannosyltransferase OCH1 and related enzymes compare
Psest_2148 +1.0 3.0 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_0100 +1.0 3.0 phosphonate ABC transporter, ATP-binding protein compare
Psest_0379 +1.0 3.8 Galactose mutarotase and related enzymes compare
Psest_1679 +1.0 1.4 ribonuclease, Rne/Rng family compare
Psest_0385 +1.0 2.4 Conserved secreted protein compare
Psest_3301 +1.0 4.3 Predicted transcriptional regulator, BolA superfamily compare
Psest_0959 +1.0 2.6 Uncharacterized protein conserved in bacteria compare
Psest_0119 +1.0 2.1 hypothetical protein compare
Psest_1424 +1.0 2.2 Lipoate-protein ligase A compare
Psest_2752 +1.0 2.1 Uncharacterized protein conserved in bacteria compare
Psest_0655 +1.0 2.4 Chemotaxis signal transduction protein compare
Psest_3114 +1.0 6.5 electron transport complex, RnfABCDGE type, C subunit compare
Psest_4265 +0.9 6.0 dTDP-4-dehydrorhamnose reductase compare
Psest_2441 +0.9 4.6 hypothetical protein compare
Psest_3575 +0.9 3.3 Arabinose efflux permease compare
Psest_2039 +0.9 3.2 PQQ-dependent catabolism-associated CXXCW motif protein compare
Psest_1277 +0.9 7.1 2-isopropylmalate synthase, yeast type compare
Psest_3112 +0.9 4.5 electron transport complex, RnfABCDGE type, A subunit compare
Psest_0558 +0.9 1.3 urease, beta subunit compare
Psest_1304 +0.9 6.8 Nucleotidyltransferase/DNA polymerase involved in DNA repair compare
Psest_4149 +0.9 3.3 fagellar hook-basal body proteins compare
Psest_3478 +0.9 1.2 Cytochrome B561 compare
Psest_0857 +0.9 0.8 Membrane transporters of cations and cationic drugs compare
Psest_3465 +0.9 5.4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0402 +0.9 2.8 glycosyltransferase, MGT family compare
Psest_4302 +0.9 4.6 hypothetical protein compare
Psest_1414 +0.9 3.9 Lactoylglutathione lyase and related lyases compare
Psest_1322 +0.9 2.1 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases compare
Psest_4008 +0.9 7.1 PAS domain S-box compare
Psest_0389 +0.9 2.3 hypothetical protein compare
Psest_2369 +0.9 2.9 Transcriptional regulator compare
Psest_1087 +0.8 1.4 uncharacterized peroxidase-related enzyme compare
Psest_3878 +0.8 3.0 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_3694 +0.8 3.8 Predicted acyltransferase compare
Psest_1506 +0.8 3.9 queuosine biosynthesis protein QueC compare
Psest_1635 +0.8 7.4 Signal transduction histidine kinase compare
Psest_1782 +0.8 1.7 Predicted transcriptional regulators compare
Psest_2150 +0.8 2.2 DNA polymerase LigD, polymerase domain compare
Psest_3462 +0.8 3.1 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_2083 +0.8 3.7 Putative sterol carrier protein compare
Psest_2119 +0.8 2.7 Glycine/D-amino acid oxidases (deaminating) compare
Psest_3490 +0.8 2.9 Signal transduction histidine kinase, nitrate/nitrite-specific compare
Psest_0779 +0.8 2.4 tyrosine aminotransferase (EC 2.6.1.57) (from data) compare
Psest_2253 +0.8 1.7 small redox-active disulfide protein 2 compare
Psest_3351 +0.8 4.7 peptide chain release factor 3 compare
Psest_2949 +0.8 5.0 Aspartyl aminopeptidase compare
Psest_3070 +0.8 1.7 3-oxoadipyl-CoA thiolase compare
Psest_0734 +0.8 2.0 RND family efflux transporter, MFP subunit compare
Psest_3459 +0.8 2.4 hypothetical protein compare
Psest_0226 +0.8 2.5 Domain of unknown function (DUF3482)./GTPase of unknown function. compare
Psest_4128 +0.8 2.0 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_2976 +0.8 1.1 hypothetical protein compare
Psest_0696 +0.8 4.3 hypothetical protein compare
Psest_3840 +0.8 2.6 D-lactate/glycolate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_0725 +0.8 1.8 Negative regulator of beta-lactamase expression compare
Psest_1306 +0.8 1.0 hypothetical protein compare
Psest_0201 +0.8 3.4 PAS domain S-box compare
Psest_1522 +0.8 2.5 hypothetical protein compare
Psest_2429 +0.8 2.3 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_4393 +0.8 3.4 Capsule polysaccharide export protein compare
Psest_0722 +0.8 5.2 Predicted ATPase compare
Psest_2628 +0.8 2.3 Flp pilus assembly protein, protease CpaA compare
Psest_3117 +0.8 3.8 electron transport complex, RnfABCDGE type, E subunit compare
Psest_3042 +0.7 1.3 Nitrate reductase cytochrome c-type subunit compare
Psest_0778 +0.7 2.4 Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin compare
Psest_1814 +0.7 5.9 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_4100 +0.7 2.7 Uncharacterized protein conserved in bacteria compare
Psest_3463 +0.7 4.1 Methylase involved in ubiquinone/menaquinone biosynthesis compare
Psest_0771 +0.7 5.6 Acyl-CoA hydrolase compare
Psest_3963 +0.7 5.9 PAS domain S-box compare
Psest_1653 +0.7 6.1 transcription-repair coupling factor (mfd) compare
Psest_2023 +0.7 2.8 isocitrate dehydrogenase, NADP-dependent, monomeric type compare
Psest_0095 +0.7 2.3 phosphonate C-P lyase system protein PhnH compare
Psest_3839 +0.7 2.9 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_0198 +0.7 4.6 TRAP transporter solute receptor, TAXI family compare
Psest_2648 +0.7 2.3 hypothetical protein compare
Psest_1879 +0.7 2.6 Trk-type K+ transport systems, membrane components compare
Psest_3295 +0.7 2.8 dinuclear metal center protein, YbgI/SA1388 family compare
Psest_0020 +0.7 3.7 K+ transport systems, NAD-binding component compare
Psest_2327 +0.7 3.8 phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein compare
Psest_1147 +0.7 2.5 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_1012 +0.7 2.9 Signal transduction histidine kinase compare
Psest_1639 +0.7 2.7 23S rRNA (uracil-5-)-methyltransferase RumA compare
Psest_1241 +0.7 4.6 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
Psest_1677 +0.7 1.3 Protein-tyrosine-phosphatase compare
Psest_0720 +0.7 4.2 Predicted hydrolase of the alpha/beta superfamily compare
Psest_0368 +0.7 1.4 Transcriptional regulator compare
Psest_4303 +0.7 1.0 HEAT repeat. compare
Psest_4305 +0.7 3.2 NAD-dependent aldehyde dehydrogenases compare
Psest_3039 +0.7 1.2 periplasmic nitrate reductase, NapE protein compare
Psest_0106 +0.7 2.9 malonate decarboxylase, gamma subunit compare
Psest_3518 +0.7 1.1 Transcriptional regulators compare
Psest_1907 +0.7 1.1 hypothetical protein compare
Psest_2551 +0.7 4.4 1-aminocyclopropane-1-carboxylate deaminase compare
Psest_3482 +0.7 2.5 Parvulin-like peptidyl-prolyl isomerase compare
Psest_0194 +0.7 4.2 hypothetical protein compare
Psest_0098 +0.7 3.1 phosphonate ABC transporter, permease protein PhnE compare
Psest_3688 +0.7 4.1 1-acyl-sn-glycerol-3-phosphate acyltransferase compare
Psest_2454 +0.7 1.1 Rhodanese-related sulfurtransferase compare
Psest_2437 +0.7 2.3 Enoyl-CoA hydratase [valine degradation] (EC 4.2.1.17) (from data) compare
Psest_2219 +0.7 3.5 pyruvate dehydrogenase E1 component, alpha subunit compare
Psest_1471 +0.7 2.7 Predicted membrane protein compare
Psest_1320 +0.7 2.5 phosphate/phosphite/phosphonate ABC transporters, periplasmic binding protein compare
Psest_0744 +0.7 1.0 Uncharacterized conserved protein compare
Psest_0243 +0.7 1.1 hypothetical protein compare
Psest_2663 +0.7 3.9 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_2629 +0.7 1.9 Flp pilus assembly protein, pilin Flp compare
Psest_0747 +0.7 2.5 Putative GTPases (G3E family) compare
Psest_4082 +0.7 2.8 hypothetical protein compare
Psest_0401 +0.7 1.0 isopentenyl-diphosphate delta-isomerase, type 2 compare
Psest_2447 +0.7 0.9 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_0510 +0.6 2.7 iojap-like ribosome-associated protein compare
Psest_3703 +0.6 4.8 3-oxoacyl-(acyl-carrier-protein) reductase, putative compare
Psest_2714 +0.6 1.5 7-cyano-7-deazaguanine reductase compare
Psest_3212 +0.6 2.5 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_1417 +0.6 0.8 hypothetical protein compare
Psest_2773 +0.6 4.3 glycerol kinase compare
Psest_2711 +0.6 1.3 PilZ domain. compare
Psest_3822 +0.6 3.2 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
Psest_1031 +0.6 3.8 Uncharacterized protein conserved in bacteria compare
Psest_1149 +0.6 1.8 Protein affecting phage T7 exclusion by the F plasmid compare
Psest_2274 +0.6 3.0 coenzyme PQQ biosynthesis protein A compare
Psest_1816 +0.6 2.7 hypothetical protein compare


Specific Phenotypes

For 16 genes in this experiment

For stress Nalidixic acid sodium salt in Pseudomonas stutzeri RCH2

For stress Nalidixic acid sodium salt across organisms