Experiment set7H32 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Nalidixic acid sodium salt 0.0005 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0153 -5.7 -10.2 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0279 -5.5 -6.5 methionine biosynthesis protein MetW compare
Psest_0326 -5.3 -13.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0152 -5.1 -7.0 Imidazoleglycerol-phosphate dehydratase compare
Psest_3647 -5.1 -4.9 Indole-3-glycerol phosphate synthase compare
Psest_0508 -5.0 -8.3 gamma-glutamyl phosphate reductase compare
Psest_3866 -5.0 -15.4 threonine ammonia-lyase, biosynthetic, long form compare
Psest_2590 -5.0 -2.6 3-isopropylmalate dehydratase, small subunit compare
Psest_3864 -5.0 -14.3 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_2584 -4.9 -3.4 Phosphoribosylanthranilate isomerase compare
Psest_3384 -4.9 -9.3 glutamate 5-kinase compare
Psest_3944 -4.8 -4.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0954 -4.8 -8.5 Fe-S oxidoreductase compare
Psest_3298 -4.7 -8.4 histidinol dehydrogenase compare
Psest_3648 -4.6 -7.1 anthranilate phosphoribosyltransferase compare
Psest_0155 -4.6 -7.0 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3650 -4.6 -10.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_3299 -4.5 -11.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0325 -4.3 -16.8 Putative threonine efflux protein compare
Psest_0953 -4.3 -12.0 iron-sulfur cluster-binding protein compare
Psest_0952 -4.3 -3.0 Uncharacterized conserved protein compare
Psest_0280 -4.3 -15.3 homoserine O-acetyltransferase compare
Psest_2589 -4.2 -11.2 3-isopropylmalate dehydrogenase compare
Psest_0062 -4.2 -10.1 tryptophan synthase, alpha subunit compare
Psest_1452 -4.2 -8.1 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_2579 -4.2 -4.1 amidophosphoribosyltransferase compare
Psest_3226 -4.1 -2.1 Predicted membrane protein compare
Psest_2578 -4.1 -12.7 O-succinylhomoserine sulfhydrylase compare
Psest_3649 -4.1 -6.3 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_2591 -3.9 -3.8 3-isopropylmalate dehydratase, large subunit compare
Psest_0063 -3.8 -6.4 tryptophan synthase, beta subunit compare
Psest_2712 -3.8 -6.2 Surface lipoprotein compare
Psest_0489 -3.8 -4.4 phosphoserine phosphatase SerB compare
Psest_3810 -3.5 -2.4 orotate phosphoribosyltransferase compare
Psest_2872 -3.5 -3.4 protein RecA compare
Psest_3305 -3.5 -8.9 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_0309 -3.4 -2.8 RND family efflux transporter, MFP subunit compare
Psest_0687 -3.4 -9.6 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_1473 -3.4 -9.4 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_3306 -3.2 -7.6 conserved hypothetical integral membrane protein compare
Psest_1295 -3.2 -6.4 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2325 -3.2 -10.3 alpha-L-glutamate ligase-related protein compare
Psest_3303 -3.1 -6.7 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1509 -3.1 -10.9 quinolinate synthetase complex, A subunit compare
Psest_1474 -3.0 -4.5 phosphoribosylaminoimidazole synthetase compare
Psest_1947 -3.0 -2.0 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_3123 -3.0 -4.4 dihydroorotase, homodimeric type compare
Psest_3159 -3.0 -9.6 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0313 -2.9 -3.9 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0466 -2.9 -5.9 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_3818 -2.8 -9.1 endoribonuclease L-PSP, putative compare
Psest_1686 -2.7 -6.1 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3129 -2.7 -2.5 tyrosine recombinase XerD compare
Psest_3767 -2.5 -6.3 tyrosine recombinase XerC compare
Psest_3307 -2.5 -8.4 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3766 -2.5 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_1496 -2.5 -2.3 Holliday junction DNA helicase, RuvA subunit compare
Psest_3943 -2.4 -3.6 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0718 -2.4 -4.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_0414 -2.4 -6.5 biotin biosynthesis protein BioC compare
Psest_1772 -2.3 -5.3 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_1013 -2.3 -4.0 phosphoribosylamine--glycine ligase compare
Psest_2324 -2.3 -13.7 hypothetical protein compare
Psest_4084 -2.3 -14.7 oxaloacetate decarboxylase alpha subunit compare
Psest_3304 -2.2 -6.4 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_1037 -2.2 -2.8 acetolactate synthase, small subunit compare
Psest_0442 -2.2 -5.5 ATPases of the AAA+ class compare
Psest_0013 -2.2 -7.3 Lauroyl/myristoyl acyltransferase compare
Psest_0411 -2.1 -10.7 biotin synthetase compare
Psest_0498 -2.1 -1.9 ribosome small subunit-dependent GTPase A compare
Psest_4085 -2.1 -14.7 Biotin carboxylase compare
Psest_0955 -2.1 -5.1 D,L-lactate:H+ symporter (from data) compare
Psest_3998 -2.0 -7.9 glutamate--cysteine ligase compare
Psest_0537 -2.0 -2.8 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_1532 -1.9 -4.5 DNA recombination-dependent growth factor C compare
Psest_2123 -1.8 -2.4 fusion of gluconokinase (EC 2.7.1.12) and the small permease component of the D-gluconate TRAP transporter (from data) compare
Psest_3720 -1.8 -12.7 penicillin-binding protein, 1A family compare
Psest_3297 -1.8 -9.2 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_2329 -1.8 -12.5 Transcriptional regulator compare
Psest_0267 -1.8 -11.1 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_2651 -1.8 -4.1 DNA topoisomerase I, bacterial compare
Psest_0310 -1.8 -3.2 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_0536 -1.7 -5.2 thiamine-phosphate pyrophosphorylase compare
Psest_4086 -1.7 -9.8 Transcriptional regulator compare
Psest_3883 -1.7 -6.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0393 -1.7 -5.8 Methylase of chemotaxis methyl-accepting proteins compare
Psest_0346 -1.7 -3.6 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_0266 -1.7 -5.5 thiamine biosynthesis protein ThiS compare
Psest_0306 -1.7 -12.2 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0477 -1.6 -10.8 thiamine biosynthesis protein ThiC compare
Psest_3449 -1.6 -1.3 DJ-1 family protein compare
Psest_0413 -1.6 -5.4 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_4191 -1.6 -2.3 Transcriptional regulator compare
Psest_3092 -1.6 -2.3 ribonuclease III, bacterial compare
Psest_2953 -1.6 -3.6 Histone acetyltransferase compare
Psest_3565 -1.6 -2.4 hypothetical protein compare
Psest_0412 -1.6 -9.4 8-amino-7-oxononanoate synthase compare
Psest_1115 -1.5 -3.2 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_2323 -1.5 -9.7 Uncharacterized protein conserved in archaea compare
Psest_0218 -1.5 -3.3 Acyl-CoA hydrolase compare
Psest_0951 -1.4 -8.2 FAD/FMN-containing dehydrogenases compare
Psest_0485 -1.4 -3.3 clan AA aspartic protease, TIGR02281 family compare
Psest_0186 -1.4 -2.8 Protein-disulfide isomerase compare
Psest_2088 -1.4 -2.5 Uncharacterized protein conserved in bacteria compare
Psest_2276 -1.4 -5.4 Aldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
Psest_4363 -1.4 -7.2 ATPases involved in chromosome partitioning compare
Psest_3464 -1.4 -6.3 Signal transduction histidine kinase compare
Psest_1870 -1.4 -2.0 Transcriptional regulators compare
Psest_2566 -1.3 -1.7 Uncharacterized protein conserved in bacteria compare
Psest_4098 -1.3 -3.1 Superfamily I DNA and RNA helicases compare
Psest_0415 -1.3 -4.2 dethiobiotin synthase compare
Psest_2316 -1.3 -8.9 phosphoenolpyruvate synthase compare
Psest_4345 -1.3 -7.2 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_3828 -1.3 -0.9 zinc-binding alcohol dehydrogenase family protein compare
Psest_1031 -1.3 -6.2 Uncharacterized protein conserved in bacteria compare
Psest_3322 -1.3 -10.1 TIGR02099 family protein compare
Psest_0133 -1.3 -2.0 type VI secretion protein, VC_A0107 family compare
Psest_2786 -1.2 -2.0 Domain of unknown function (DUF3597). compare
Psest_3890 -1.2 -1.1 Multisubunit Na+/H+ antiporter, MnhB subunit compare
Psest_0146 -1.2 -5.6 Uncharacterized protein involved in outer membrane biogenesis compare
Psest_3374 -1.2 -7.8 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_4219 -1.2 -2.6 DNA polymerase I compare
Psest_1888 -1.2 -1.3 Sua5/YciO/YrdC/YwlC family protein compare
Psest_1837 -1.2 -6.5 Endoglucanase compare
Psest_3721 -1.2 -5.6 Malic enzyme compare
Psest_2136 -1.1 -5.4 Predicted homoserine dehydrogenase compare
Psest_0311 -1.1 -3.5 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_2379 -1.1 -6.4 PAS domain S-box compare
Psest_3990 -1.1 -6.5 PAP2 superfamily. compare
Psest_4307 -1.1 -2.1 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_1920 -1.1 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_3317 -1.1 -3.9 Phosphotransferase System HPr (HPr) Family compare
Psest_2646 -1.1 -2.4 SOS regulatory protein LexA compare
Psest_4049 -1.1 -2.1 hypothetical protein compare
Psest_2104 -1.0 -2.4 IscR-regulated protein YhgI compare
Psest_3128 -1.0 -3.6 Protein-disulfide isomerase compare
Psest_2810 -1.0 -4.2 5'/3'-nucleotidase SurE compare
Psest_2711 -1.0 -2.0 PilZ domain. compare
Psest_0334 -1.0 -3.0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3286 -1.0 -4.3 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_1144 -1.0 -1.8 AmpG-related permease compare
Psest_1704 -1.0 -1.6 Dehydrogenases (flavoproteins) compare
Psest_1054 -1.0 -4.5 Diaminopimelate decarboxylase compare
Psest_3476 -1.0 -1.2 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0257 -1.0 -2.1 Predicted Zn-dependent peptidases compare
Psest_1752 -1.0 -1.7 Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB compare
Psest_3399 -1.0 -1.9 Uncharacterized protein conserved in bacteria compare
Psest_3862 -1.0 -7.5 phosphoenolpyruvate-protein phosphotransferase compare
Psest_2864 -0.9 -3.7 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_3717 -0.9 -4.3 Tfp pilus assembly protein PilO compare
Psest_4044 -0.9 -3.8 type I site-specific deoxyribonuclease, HsdR family compare
Psest_3458 -0.9 -1.2 hypothetical protein compare
Psest_0484 -0.9 -2.9 hypothetical protein compare
Psest_1640 -0.9 -6.4 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_2232 -0.9 -6.4 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_3707 -0.9 -1.9 Transcriptional regulator compare
Psest_2988 -0.9 -3.6 aspartate kinase, monofunctional class compare
Psest_2308 -0.9 -1.3 Predicted Fe-S protein compare
Psest_0031 -0.9 -1.7 Uncharacterized conserved protein compare
Psest_4406 -0.9 -1.5 hypothetical protein compare
Psest_0300 -0.9 -5.3 Methyl-accepting chemotaxis protein compare
Psest_1078 -0.9 -2.8 acetyl-CoA:acetoacetate CoA transferase, A subunit (EC 2.8.3.8) (from data) compare
Psest_3222 -0.9 -1.3 Putative threonine efflux protein compare
Psest_2460 -0.9 -2.0 hypothetical protein compare
Psest_3719 -0.8 -5.9 type IV pilus assembly protein PilM compare
Psest_3447 -0.8 -0.8 Uncharacterized MobA-related protein compare
Psest_3031 -0.8 -1.0 hypothetical protein compare
Psest_1284 -0.8 -2.6 exodeoxyribonuclease VII, large subunit compare
Psest_1292 -0.8 -4.7 monothiol glutaredoxin, Grx4 family compare
Psest_3555 -0.8 -2.2 Predicted methyltransferase compare
Psest_1022 -0.8 -5.2 Thiol:disulfide interchange protein compare
Psest_3373 -0.8 -3.9 Tfp pilus assembly protein PilX compare
Psest_0327 -0.8 -2.8 Transcriptional regulator compare
Psest_2809 -0.8 -1.7 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_4201 -0.8 -1.5 general secretion pathway protein F compare
Psest_3884 -0.8 -0.7 Signal transduction histidine kinase compare
Psest_2887 -0.8 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_3908 -0.8 -0.9 Cytochrome c553 compare
Psest_1511 -0.8 -2.8 Predicted redox protein, regulator of disulfide bond formation compare
Psest_3749 -0.8 -5.5 Response regulator of the LytR/AlgR family compare
Psest_3230 -0.8 -3.9 Uncharacterized conserved protein compare
Psest_2532 -0.8 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_4298 -0.7 -0.9 Response regulator containing a CheY-like receiver domain and a GGDEF domain compare
Psest_3372 -0.7 -4.5 Tfp pilus assembly protein PilW compare
Psest_1153 -0.7 -6.5 Cation/multidrug efflux pump compare
Psest_1397 -0.7 -2.2 ABC-type nitrate/sulfonate/bicarbonate transport system, permease component compare
Psest_0284 -0.7 -5.4 pyridoxal phosphate enzyme, YggS family compare
Psest_1940 -0.7 -2.2 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain compare
Psest_2641 -0.7 -4.8 Conserved secreted protein compare
Psest_1218 -0.7 -2.6 Predicted endonuclease containing a URI domain compare
Psest_1591 -0.7 -3.8 hypothetical protein compare
Psest_2768 -0.7 -1.5 Kef-type K+ transport systems, predicted NAD-binding component compare
Psest_4325 -0.7 -2.3 hypothetical protein compare
Psest_0275 -0.7 -2.9 Protein of unknown function (DUF3392). compare
Psest_0078 -0.7 -1.0 hypothetical protein compare
Psest_2643 -0.7 -0.9 Beta-glucosidase-related glycosidases compare
Psest_0962 -0.7 -4.4 DNA repair protein RecN conserved
Psest_0316 -0.7 -1.8 Cytochrome c556 compare
Psest_0114 -0.7 -1.2 RNA polymerase sigma factor, sigma-70 family compare
Psest_2586 -0.7 -5.8 FimV N-terminal domain compare


Specific Phenotypes

For 2 genes in this experiment

For stress Nalidixic acid sodium salt in Pseudomonas stutzeri RCH2

For stress Nalidixic acid sodium salt across organisms