Experiment set7H29 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Tetracycline hydrochloride 0.0004 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0152 -5.9 -5.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_0153 -5.2 -12.0 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_3944 -5.2 -3.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_2590 -5.1 -2.5 3-isopropylmalate dehydratase, small subunit compare
Psest_2584 -5.1 -3.5 Phosphoribosylanthranilate isomerase compare
Psest_3650 -4.8 -8.1 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0155 -4.8 -6.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3298 -4.8 -9.7 histidinol dehydrogenase compare
Psest_3648 -4.7 -5.5 anthranilate phosphoribosyltransferase compare
Psest_0954 -4.6 -8.7 Fe-S oxidoreductase compare
Psest_3647 -4.5 -6.1 Indole-3-glycerol phosphate synthase compare
Psest_0953 -4.5 -12.2 iron-sulfur cluster-binding protein compare
Psest_3299 -4.5 -12.3 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0508 -4.5 -9.0 gamma-glutamyl phosphate reductase compare
Psest_2578 -4.4 -13.2 O-succinylhomoserine sulfhydrylase compare
Psest_0279 -4.4 -7.3 methionine biosynthesis protein MetW compare
Psest_3866 -4.4 -17.7 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3864 -4.4 -15.0 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0062 -4.3 -8.7 tryptophan synthase, alpha subunit compare
Psest_2579 -4.2 -5.7 amidophosphoribosyltransferase compare
Psest_1473 -4.1 -9.8 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0325 -4.0 -20.0 Putative threonine efflux protein compare
Psest_0687 -3.9 -7.0 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0489 -3.9 -3.8 phosphoserine phosphatase SerB compare
Psest_0280 -3.8 -15.8 homoserine O-acetyltransferase compare
Psest_2591 -3.8 -4.5 3-isopropylmalate dehydratase, large subunit compare
Psest_1452 -3.8 -10.7 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_3384 -3.8 -11.6 glutamate 5-kinase compare
Psest_0063 -3.8 -5.7 tryptophan synthase, beta subunit compare
Psest_0013 -3.7 -5.6 Lauroyl/myristoyl acyltransferase compare
Psest_2589 -3.6 -12.4 3-isopropylmalate dehydrogenase compare
Psest_0952 -3.5 -4.1 Uncharacterized conserved protein compare
Psest_0326 -3.4 -13.6 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_1474 -3.4 -4.1 phosphoribosylaminoimidazole synthetase compare
Psest_1509 -3.2 -11.1 quinolinate synthetase complex, A subunit compare
Psest_3810 -3.1 -3.0 orotate phosphoribosyltransferase compare
Psest_3159 -3.1 -10.1 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0718 -3.1 -4.6 nicotinate-nucleotide pyrophosphorylase compare
Psest_0313 -3.0 -3.0 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3884 -3.0 -1.4 Signal transduction histidine kinase compare
Psest_1013 -2.9 -2.8 phosphoribosylamine--glycine ligase compare
Psest_3226 -2.9 -1.9 Predicted membrane protein compare
Psest_1295 -2.9 -6.9 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3649 -2.8 -8.9 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_2325 -2.8 -10.3 alpha-L-glutamate ligase-related protein compare
Psest_1947 -2.7 -3.1 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_3372 -2.6 -10.7 Tfp pilus assembly protein PilW compare
Psest_0537 -2.5 -3.2 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_3373 -2.5 -7.7 Tfp pilus assembly protein PilX compare
Psest_2324 -2.5 -14.6 hypothetical protein compare
Psest_2308 -2.4 -2.1 Predicted Fe-S protein compare
Psest_3374 -2.4 -11.4 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_0466 -2.4 -5.5 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_2944 -2.3 -2.6 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_0691 -2.3 -14.0 ribonuclease R compare
Psest_0334 -2.2 -4.0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_3943 -2.2 -3.4 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0266 -2.1 -6.2 thiamine biosynthesis protein ThiS compare
Psest_1772 -2.1 -5.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0536 -2.1 -5.7 thiamine-phosphate pyrophosphorylase compare
Psest_0442 -2.1 -5.2 ATPases of the AAA+ class compare
Psest_3371 -2.0 -8.5 type IV pilus modification protein PilV compare
Psest_0097 -2.0 -1.8 phosphonates metabolism transcriptional regulator PhnF compare
Psest_1154 -1.9 -10.0 RND family efflux transporter, MFP subunit compare
Psest_1115 -1.9 -4.7 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1940 -1.9 -4.2 Uncharacterized protein containing a von Willebrand factor type A (vWA) domain compare
Psest_3565 -1.9 -2.7 hypothetical protein compare
Psest_1153 -1.8 -15.2 Cation/multidrug efflux pump compare
Psest_3990 -1.8 -7.7 PAP2 superfamily. compare
Psest_0257 -1.7 -3.4 Predicted Zn-dependent peptidases compare
Psest_0476 -1.7 -8.4 type I secretion outer membrane protein, TolC family compare
Psest_0267 -1.7 -9.9 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_3092 -1.6 -2.4 ribonuclease III, bacterial compare
Psest_3370 -1.6 -6.5 prepilin-type N-terminal cleavage/methylation domain compare
Psest_3123 -1.6 -3.0 dihydroorotase, homodimeric type compare
Psest_3303 -1.6 -6.2 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1686 -1.5 -5.3 fatty acid/phospholipid synthesis protein PlsX compare
Psest_0477 -1.5 -9.5 thiamine biosynthesis protein ThiC compare
Psest_0393 -1.5 -5.3 Methylase of chemotaxis methyl-accepting proteins compare
Psest_3896 -1.4 -2.0 arsenite-activated ATPase ArsA compare
Psest_0311 -1.4 -4.0 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_2304 -1.4 -1.8 Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family compare
Psest_3883 -1.4 -5.3 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_4191 -1.4 -2.0 Transcriptional regulator compare
Psest_4345 -1.4 -7.6 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_3535 -1.3 -3.4 hypothetical protein compare
Psest_0411 -1.3 -7.9 biotin synthetase compare
Psest_3862 -1.3 -9.7 phosphoenolpyruvate-protein phosphotransferase compare
Psest_3766 -1.3 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_2067 -1.3 -1.6 ABC-type oligopeptide transport system, periplasmic component compare
Psest_0484 -1.3 -3.2 hypothetical protein compare
Psest_0955 -1.3 -4.7 D,L-lactate:H+ symporter (from data) compare
Psest_1496 -1.3 -1.5 Holliday junction DNA helicase, RuvA subunit compare
Psest_1144 -1.3 -1.7 AmpG-related permease compare
Psest_1054 -1.3 -5.7 Diaminopimelate decarboxylase compare
Psest_3818 -1.2 -5.8 endoribonuclease L-PSP, putative compare
Psest_0292 -1.2 -2.7 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_1510 -1.2 -3.3 Putative Zn-dependent protease, contains TPR repeats compare
Psest_1724 -1.2 -3.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1532 -1.2 -3.7 DNA recombination-dependent growth factor C compare
Psest_0186 -1.2 -2.5 Protein-disulfide isomerase compare
Psest_1923 -1.2 -4.3 adhesin-associated BNR repeat protein (from data) compare
Psest_2323 -1.1 -7.3 Uncharacterized protein conserved in archaea compare
Psest_3395 -1.1 -1.8 hypothetical protein compare
Psest_3045 -1.1 -2.8 Cold shock proteins compare
Psest_3720 -1.1 -8.3 penicillin-binding protein, 1A family compare
Psest_3464 -1.1 -6.6 Signal transduction histidine kinase compare
Psest_0725 -1.1 -1.8 Negative regulator of beta-lactamase expression compare
Psest_3767 -1.0 -3.8 tyrosine recombinase XerC compare
Psest_2586 -1.0 -9.0 FimV N-terminal domain compare
Psest_3998 -1.0 -4.8 glutamate--cysteine ligase compare
Psest_2945 -1.0 -1.6 septum site-determining protein MinC compare
Psest_3927 -1.0 -3.3 thiazole biosynthesis/tRNA modification protein ThiI compare
Psest_0031 -1.0 -1.7 Uncharacterized conserved protein compare
Psest_3304 -1.0 -3.4 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_1540 -1.0 -1.7 biotin-dependent carboxylase uncharacterized domain compare
Psest_0309 -1.0 -1.3 RND family efflux transporter, MFP subunit compare
Psest_4307 -0.9 -1.7 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_4044 -0.9 -3.5 type I site-specific deoxyribonuclease, HsdR family compare
Psest_0103 -0.9 -1.3 triphosphoribosyl-dephospho-CoA synthase MdcB compare
Psest_0538 -0.9 -8.9 Signal transduction histidine kinase compare
Psest_4335 -0.9 -2.3 Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems compare
Psest_1122 -0.9 -7.9 putative adhesin (DUF1302) (from data) compare
Psest_0041 -0.9 -3.4 Uncharacterized protein conserved in bacteria compare
Psest_3317 -0.9 -3.2 Phosphotransferase System HPr (HPr) Family compare
Psest_0951 -0.9 -5.7 FAD/FMN-containing dehydrogenases compare
Psest_3128 -0.9 -3.1 Protein-disulfide isomerase compare
Psest_0310 -0.9 -2.0 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_4274 -0.9 -2.4 hypothetical protein compare
Psest_0277 -0.9 -1.7 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_1227 -0.9 -2.5 Predicted SAM-dependent methyltransferase compare
Psest_3322 -0.9 -7.4 TIGR02099 family protein compare
Psest_2864 -0.9 -2.5 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_3718 -0.9 -4.1 Tfp pilus assembly protein PilN compare
Psest_0218 -0.9 -2.1 Acyl-CoA hydrolase compare
Psest_3716 -0.9 -5.4 Tfp pilus assembly protein PilP compare
Psest_0457 -0.9 -2.7 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1527 -0.9 -6.3 Na+/proline symporter compare
Psest_0300 -0.9 -5.5 Methyl-accepting chemotaxis protein compare
Psest_1260 -0.9 -4.3 type IV pilus biogenesis/stability protein PilW compare
Psest_0170 -0.9 -4.0 5,10-methenyltetrahydrofolate synthetase compare
Psest_2712 -0.9 -3.3 Surface lipoprotein compare
Psest_3832 -0.9 -1.4 hypothetical protein compare
Psest_3921 -0.8 -2.2 Uncharacterized protein conserved in bacteria compare
Psest_2329 -0.8 -6.4 Transcriptional regulator compare
Psest_3339 -0.8 -3.7 Signal transduction histidine kinase compare
Psest_1567 -0.8 -3.6 Transcriptional regulator compare
Psest_1339 -0.8 -4.9 ATP-dependent helicase HrpA compare
Psest_0028 -0.8 -2.7 Coproporphyrinogen III oxidase compare
Psest_1625 -0.8 -2.7 hypothetical protein compare
Psest_1511 -0.8 -2.5 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0485 -0.8 -2.3 clan AA aspartic protease, TIGR02281 family compare
Psest_3715 -0.8 -6.2 type IV pilus secretin (or competence protein) PilQ compare
Psest_3297 -0.8 -4.9 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_4341 -0.8 -3.5 hypothetical protein compare
Psest_0181 -0.8 -4.0 glycine cleavage system T protein compare
Psest_3305 -0.8 -4.5 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_3458 -0.8 -1.0 hypothetical protein compare
Psest_1924 -0.8 -6.5 adhesin-associated MmpL efflux pump (from data) compare
Psest_2645 -0.8 -4.3 Transcriptional regulator compare
Psest_2276 -0.8 -2.8 Aldehyde dehydrogenase (EC 1.2.1.3) (from data) compare
Psest_3145 -0.8 -1.7 hypothetical protein compare
Psest_0327 -0.8 -3.9 Transcriptional regulator compare
Psest_1643 -0.7 -1.2 hypothetical protein compare
Psest_3719 -0.7 -5.1 type IV pilus assembly protein PilM compare
Psest_1022 -0.7 -4.6 Thiol:disulfide interchange protein compare
Psest_0349 -0.7 -3.9 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_4370 -0.7 -1.5 Multisubunit Na+/H+ antiporter, MnhC subunit compare
Psest_0696 -0.7 -4.0 hypothetical protein compare
Psest_1055 -0.7 -4.8 Saccharopine dehydrogenase and related proteins compare
Psest_4363 -0.7 -4.1 ATPases involved in chromosome partitioning compare
Psest_2726 -0.7 -1.7 Rhodanese-related sulfurtransferase compare
Psest_0260 -0.7 -1.5 Cell division protein compare
Psest_2104 -0.7 -1.8 IscR-regulated protein YhgI compare
Psest_2718 -0.7 -1.1 hypothetical protein compare
Psest_2316 -0.7 -5.4 phosphoenolpyruvate synthase compare
Psest_3275 -0.7 -3.2 Stringent starvation protein B compare
Psest_3228 -0.7 -4.7 Zn-dependent protease with chaperone function compare
Psest_3286 -0.7 -3.3 Type II secretory pathway, prepilin signal peptidase PulO and related peptidases compare
Psest_2379 -0.7 -4.6 PAS domain S-box compare
Psest_0744 -0.7 -0.8 Uncharacterized conserved protein compare
Psest_3960 -0.7 -1.2 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_0302 -0.7 -6.4 Chemotaxis protein histidine kinase and related kinases compare
Psest_3749 -0.7 -5.0 Response regulator of the LytR/AlgR family compare
Psest_0708 -0.7 -1.1 outer membrane assembly lipoprotein YfiO compare
Psest_2667 -0.7 -1.5 Uncharacterized protein involved in propionate catabolism compare
Psest_1459 -0.7 -2.4 hypothetical protein compare
Psest_2218 -0.7 -1.8 Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit compare
Psest_2531 -0.7 -5.2 cytochrome c oxidase accessory protein FixG compare
Psest_3296 -0.7 -3.0 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_0998 -0.7 -2.0 poly(A) polymerase compare
Psest_3717 -0.6 -3.1 Tfp pilus assembly protein PilO compare
Psest_0958 -0.6 -3.5 Oligoketide cyclase/lipid transport protein compare
Psest_0741 -0.6 -3.1 drug resistance transporter, Bcr/CflA subfamily compare
Psest_2243 -0.6 -1.0 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1939 -0.6 -3.3 Tetratricopeptide repeat. compare
Psest_3790 -0.6 -3.9 Cytochrome c5 compare
Psest_4202 -0.6 -3.2 general secretory pathway protein E compare
Psest_1640 -0.6 -4.7 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_2173 -0.6 -2.6 competence/damage-inducible protein CinA C-terminal domain compare


Specific Phenotypes

For 4 genes in this experiment

For stress Tetracycline hydrochloride in Pseudomonas stutzeri RCH2

For stress Tetracycline hydrochloride across organisms