Experiment set7H21 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Doxycycline hyclate 0.0002 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0153 -6.4 -6.2 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_1473 -6.1 -7.2 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_2584 -5.8 -5.6 Phosphoribosylanthranilate isomerase compare
Psest_2712 -5.7 -5.5 Surface lipoprotein compare
Psest_3647 -5.6 -6.6 Indole-3-glycerol phosphate synthase compare
Psest_2578 -5.5 -12.8 O-succinylhomoserine sulfhydrylase compare
Psest_2591 -5.5 -3.8 3-isopropylmalate dehydratase, large subunit compare
Psest_2579 -5.4 -3.7 amidophosphoribosyltransferase compare
Psest_2590 -5.4 -2.6 3-isopropylmalate dehydratase, small subunit compare
Psest_3650 -5.4 -9.6 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0155 -5.2 -5.1 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_3648 -5.2 -6.2 anthranilate phosphoribosyltransferase compare
Psest_0152 -5.2 -6.8 Imidazoleglycerol-phosphate dehydratase compare
Psest_3866 -5.2 -16.2 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3864 -5.2 -13.3 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_0952 -5.0 -4.8 Uncharacterized conserved protein compare
Psest_3298 -5.0 -10.1 histidinol dehydrogenase compare
Psest_1509 -5.0 -11.5 quinolinate synthetase complex, A subunit compare
Psest_0508 -5.0 -8.3 gamma-glutamyl phosphate reductase compare
Psest_1295 -4.9 -6.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3384 -4.8 -9.8 glutamate 5-kinase compare
Psest_3299 -4.8 -12.8 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0953 -4.7 -12.8 iron-sulfur cluster-binding protein compare
Psest_3944 -4.7 -3.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0954 -4.6 -12.9 Fe-S oxidoreductase compare
Psest_0062 -4.6 -9.8 tryptophan synthase, alpha subunit compare
Psest_2589 -4.6 -13.6 3-isopropylmalate dehydrogenase compare
Psest_0411 -4.5 -11.2 biotin synthetase compare
Psest_3306 -4.5 -7.4 conserved hypothetical integral membrane protein compare
Psest_3649 -4.4 -9.4 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0279 -4.4 -7.3 methionine biosynthesis protein MetW compare
Psest_0326 -4.3 -14.2 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0280 -4.2 -15.8 homoserine O-acetyltransferase compare
Psest_0325 -4.2 -16.8 Putative threonine efflux protein compare
Psest_0687 -4.2 -9.8 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3159 -4.2 -10.4 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1452 -4.1 -8.4 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_0718 -4.1 -4.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_3307 -4.0 -10.1 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3305 -4.0 -10.9 ABC-type transport system involved in resistance to organic solvents, periplasmic component compare
Psest_0063 -4.0 -7.6 tryptophan synthase, beta subunit compare
Psest_1474 -3.8 -4.6 phosphoribosylaminoimidazole synthetase compare
Psest_3303 -3.8 -9.4 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_1013 -3.6 -4.9 phosphoribosylamine--glycine ligase compare
Psest_3304 -3.6 -7.9 ABC-type transport system involved in resistance to organic solvents, auxiliary component compare
Psest_0489 -3.5 -3.4 phosphoserine phosphatase SerB compare
Psest_3810 -3.5 -3.4 orotate phosphoribosyltransferase compare
Psest_0013 -3.3 -8.7 Lauroyl/myristoyl acyltransferase compare
Psest_1772 -3.2 -6.6 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_3818 -3.1 -8.5 endoribonuclease L-PSP, putative compare
Psest_0313 -3.0 -3.5 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_0266 -3.0 -7.5 thiamine biosynthesis protein ThiS compare
Psest_3721 -3.0 -9.8 Malic enzyme compare
Psest_0477 -3.0 -14.6 thiamine biosynthesis protein ThiC compare
Psest_3226 -2.9 -2.4 Predicted membrane protein compare
Psest_0466 -2.9 -6.7 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0267 -2.9 -13.3 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_4084 -2.8 -16.4 oxaloacetate decarboxylase alpha subunit compare
Psest_3338 -2.8 -2.6 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_1947 -2.7 -2.6 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1115 -2.7 -5.4 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_4085 -2.7 -16.3 Biotin carboxylase compare
Psest_2944 -2.6 -3.1 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_1153 -2.5 -19.7 Cation/multidrug efflux pump conserved
Psest_1154 -2.5 -11.4 RND family efflux transporter, MFP subunit compare
Psest_3297 -2.5 -9.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_0442 -2.4 -8.1 ATPases of the AAA+ class compare
Psest_0536 -2.4 -4.2 thiamine-phosphate pyrophosphorylase compare
Psest_3943 -2.3 -4.0 Phosphoribosyl-AMP cyclohydrolase compare
Psest_3123 -2.3 -3.5 dihydroorotase, homodimeric type compare
Psest_0334 -2.3 -4.0 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0476 -2.3 -9.3 type I secretion outer membrane protein, TolC family compare
Psest_2864 -2.2 -6.6 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_2324 -2.2 -17.2 hypothetical protein compare
Psest_3990 -2.2 -9.5 PAP2 superfamily. compare
Psest_3883 -2.2 -6.1 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0170 -2.2 -6.2 5,10-methenyltetrahydrofolate synthetase compare
Psest_2325 -2.1 -12.4 alpha-L-glutamate ligase-related protein compare
Psest_2650 -2.1 -4.0 hypothetical protein compare
Psest_0306 -1.9 -13.2 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_0412 -1.9 -10.5 8-amino-7-oxononanoate synthase compare
Psest_1496 -1.8 -3.0 Holliday junction DNA helicase, RuvA subunit compare
Psest_0414 -1.7 -5.3 biotin biosynthesis protein BioC compare
Psest_3710 -1.7 -11.3 glutamate synthase small subunit family protein, proteobacterial compare
Psest_0207 -1.7 -2.7 hypothetical protein compare
Psest_1037 -1.7 -2.3 acetolactate synthase, small subunit compare
Psest_1527 -1.7 -11.4 Na+/proline symporter compare
Psest_1837 -1.7 -9.9 Endoglucanase compare
Psest_4086 -1.7 -9.9 Transcriptional regulator compare
Psest_0955 -1.6 -4.0 D,L-lactate:H+ symporter (from data) compare
Psest_3884 -1.6 -1.0 Signal transduction histidine kinase compare
Psest_1012 -1.6 -4.7 Signal transduction histidine kinase compare
Psest_2329 -1.6 -12.0 Transcriptional regulator compare
Psest_3565 -1.6 -2.3 hypothetical protein compare
Psest_3373 -1.6 -6.4 Tfp pilus assembly protein PilX compare
Psest_2104 -1.6 -3.4 IscR-regulated protein YhgI compare
Psest_2025 -1.5 -2.0 cold shock domain protein CspD compare
Psest_2331 -1.5 -9.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
Psest_0310 -1.5 -3.2 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_0457 -1.5 -4.0 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_1920 -1.5 -1.5 Uncharacterized protein conserved in bacteria compare
Psest_2719 -1.4 -4.3 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_0415 -1.4 -4.6 dethiobiotin synthase compare
Psest_3711 -1.4 -10.1 Glutamate synthase domain 2 compare
Psest_3518 -1.4 -1.7 Transcriptional regulators compare
Psest_0346 -1.4 -3.2 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_2316 -1.4 -10.7 phosphoenolpyruvate synthase compare
Psest_3749 -1.4 -8.6 Response regulator of the LytR/AlgR family compare
Psest_3464 -1.4 -7.6 Signal transduction histidine kinase conserved
Psest_4345 -1.3 -6.9 Bacteriophytochrome (light-regulated signal transduction histidine kinase) compare
Psest_0327 -1.3 -4.5 Transcriptional regulator compare
Psest_0413 -1.3 -5.6 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_3371 -1.3 -7.1 type IV pilus modification protein PilV compare
Psest_3372 -1.3 -7.8 Tfp pilus assembly protein PilW compare
Psest_0212 -1.3 -1.4 exodeoxyribonuclease V, gamma subunit compare
Psest_2243 -1.3 -1.8 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_1511 -1.3 -2.9 Predicted redox protein, regulator of disulfide bond formation compare
Psest_0722 -1.2 -6.6 Predicted ATPase compare
Psest_4219 -1.2 -2.1 DNA polymerase I compare
Psest_0218 -1.2 -2.7 Acyl-CoA hydrolase compare
Psest_3374 -1.2 -8.1 Tfp pilus assembly protein, tip-associated adhesin PilY1 compare
Psest_3766 -1.2 -2.0 Uncharacterized protein conserved in bacteria compare
Psest_0951 -1.2 -7.1 FAD/FMN-containing dehydrogenases compare
Psest_3128 -1.1 -4.8 Protein-disulfide isomerase compare
Psest_1054 -1.1 -5.0 Diaminopimelate decarboxylase compare
Psest_2334 -1.1 -9.2 Uncharacterized protein conserved in bacteria compare
Psest_1724 -1.1 -3.9 Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) compare
Psest_0537 -1.1 -1.4 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_0969 -1.1 -2.9 transcription elongation factor GreA compare
Psest_0515 -1.1 -4.1 rare lipoprotein A compare
Psest_3377 -1.1 -1.5 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_1277 -1.1 -7.4 2-isopropylmalate synthase, yeast type compare
Psest_4128 -1.1 -1.2 Universal stress protein UspA and related nucleotide-binding proteins compare
Psest_4323 -1.1 -8.2 Predicted acyltransferases compare
Psest_1055 -1.1 -6.3 Saccharopine dehydrogenase and related proteins compare
Psest_3664 -1.1 -1.5 Predicted phosphotransferase related to Ser/Thr protein kinases compare
Psest_3339 -1.1 -4.6 Signal transduction histidine kinase compare
Psest_3047 -1.1 -1.7 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_2323 -1.1 -6.3 Uncharacterized protein conserved in archaea compare
Psest_3932 -1.0 -3.5 nitrogen regulation protein NR(I) compare
Psest_2585 -1.0 -1.0 pseudouridylate synthase I compare
Psest_0257 -1.0 -2.5 Predicted Zn-dependent peptidases compare
Psest_2757 -1.0 -1.9 hypothetical protein compare
Psest_1292 -1.0 -6.0 monothiol glutaredoxin, Grx4 family compare
Psest_2809 -1.0 -3.4 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
Psest_3962 -1.0 -2.1 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_3296 -1.0 -3.2 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_0867 -1.0 -1.6 hypothetical protein compare
Psest_3998 -1.0 -4.4 glutamate--cysteine ligase compare
Psest_2126 -1.0 -3.9 Transcriptional regulators compare
Psest_0193 -1.0 -1.2 conserved hypothetical protein compare
Psest_3177 -1.0 -1.9 hypothetical protein compare
Psest_1417 -1.0 -1.3 hypothetical protein compare
Psest_0393 -1.0 -4.5 Methylase of chemotaxis methyl-accepting proteins compare
Psest_2531 -1.0 -7.6 cytochrome c oxidase accessory protein FixG compare
Psest_2988 -1.0 -3.7 aspartate kinase, monofunctional class compare
Psest_3447 -1.0 -0.6 Uncharacterized MobA-related protein compare
Psest_3092 -1.0 -2.1 ribonuclease III, bacterial compare
Psest_3370 -1.0 -6.3 prepilin-type N-terminal cleavage/methylation domain compare
Psest_1636 -1.0 -2.5 putative transporter, required for glycine utilization (from data) compare
Psest_2945 -1.0 -1.4 septum site-determining protein MinC compare
Psest_2070 -1.0 -5.3 FOG: LysM repeat compare
Psest_0164 -0.9 -1.0 Glutaredoxin, GrxC family compare
Psest_1640 -0.9 -6.8 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_3536 -0.9 -1.6 hypothetical protein compare
Psest_0511 -0.9 -1.3 rRNA large subunit m3Psi methyltransferase RlmH compare
Psest_2946 -0.9 -2.9 septum site-determining protein MinD compare
Psest_1686 -0.9 -3.6 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3231 -0.9 -1.5 hypothetical protein compare
Psest_2646 -0.9 -2.1 SOS regulatory protein LexA compare
Psest_3853 -0.9 -2.3 ABC-type branched-chain amino acid transport systems, ATPase component compare
Psest_3100 -0.9 -5.7 RNA polymerase sigma factor RpoE compare
Psest_3455 -0.9 -1.1 Dihaem cytochrome c. compare
Psest_4044 -0.9 -3.5 type I site-specific deoxyribonuclease, HsdR family compare
Psest_2434 -0.8 -1.3 Protein of unknown function (DUF2892). compare
Psest_2632 -0.8 -3.6 ribosomal protein S12 methylthiotransferase RimO compare
Psest_3931 -0.8 -2.4 Signal transduction histidine kinase, nitrogen specific compare
Psest_1306 -0.8 -1.3 hypothetical protein compare
Psest_3862 -0.8 -6.4 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0998 -0.8 -2.1 poly(A) polymerase compare
Psest_1942 -0.8 -4.1 Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) compare
Psest_2317 -0.8 -4.8 Uncharacterized protein conserved in bacteria compare
Psest_3788 -0.8 -2.4 xanthine phosphoribosyltransferase compare
Psest_2446 -0.8 -1.3 acetyl-CoA acetyltransferases compare
Psest_0031 -0.8 -0.8 Uncharacterized conserved protein compare
Psest_2629 -0.8 -1.8 Flp pilus assembly protein, pilin Flp compare
Psest_2130 -0.8 -2.5 exodeoxyribonuclease III compare
Psest_0709 -0.8 -4.7 pseudouridine synthase, RluA family compare
Psest_3367 -0.8 -1.2 translation initation factor SUI1, putative, prokaryotic compare
Psest_0691 -0.8 -5.3 ribonuclease R compare
Psest_2530 -0.7 -3.6 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_4390 -0.7 -2.7 hypothetical protein compare
Psest_2634 -0.7 -2.5 glycine betaine aldehyde dehydrogenase compare
Psest_3860 -0.7 -1.5 Predicted permeases compare
Psest_1305 -0.7 -2.3 Heat shock protein compare
Psest_0349 -0.7 -3.7 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_1419 -0.7 -2.8 Transcriptional regulator compare
Psest_3809 -0.7 -2.8 hypothetical protein compare
Psest_1438 -0.7 -3.5 Transcriptional regulator compare
Psest_1031 -0.7 -3.8 Uncharacterized protein conserved in bacteria compare


Specific Phenotypes

For 5 genes in this experiment

For stress Doxycycline hyclate in Pseudomonas stutzeri RCH2

For stress Doxycycline hyclate across organisms