Experiment set7H11 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Cephalothin sodium salt 0.04 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_0152 -6.4 -4.4 Imidazoleglycerol-phosphate dehydratase compare
Psest_3647 -6.2 -4.3 Indole-3-glycerol phosphate synthase compare
Psest_0153 -5.9 -10.6 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_2584 -5.7 -4.0 Phosphoribosylanthranilate isomerase compare
Psest_2591 -5.2 -3.6 3-isopropylmalate dehydratase, large subunit compare
Psest_0508 -5.2 -7.1 gamma-glutamyl phosphate reductase compare
Psest_3384 -5.1 -7.8 glutamate 5-kinase compare
Psest_2864 -5.0 -5.9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_0954 -4.9 -10.4 Fe-S oxidoreductase compare
Psest_3650 -4.9 -11.4 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_0708 -4.9 -3.4 outer membrane assembly lipoprotein YfiO compare
Psest_3864 -4.9 -13.7 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3648 -4.9 -6.7 anthranilate phosphoribosyltransferase compare
Psest_1037 -4.9 -3.9 acetolactate synthase, small subunit compare
Psest_0279 -4.8 -6.6 methionine biosynthesis protein MetW compare
Psest_3226 -4.8 -1.7 Predicted membrane protein compare
Psest_2088 -4.7 -3.5 Uncharacterized protein conserved in bacteria compare
Psest_3298 -4.7 -7.9 histidinol dehydrogenase compare
Psest_0155 -4.7 -6.4 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_0952 -4.7 -4.5 Uncharacterized conserved protein compare
Psest_3866 -4.6 -17.3 threonine ammonia-lyase, biosynthetic, long form compare
Psest_3944 -4.6 -3.2 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_1295 -4.6 -7.6 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0953 -4.6 -11.2 iron-sulfur cluster-binding protein compare
Psest_2578 -4.5 -14.7 O-succinylhomoserine sulfhydrylase compare
Psest_0062 -4.5 -10.5 tryptophan synthase, alpha subunit compare
Psest_1509 -4.4 -12.1 quinolinate synthetase complex, A subunit compare
Psest_0326 -4.3 -15.5 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_0718 -4.3 -4.2 nicotinate-nucleotide pyrophosphorylase compare
Psest_2579 -4.3 -8.7 amidophosphoribosyltransferase compare
Psest_3299 -4.3 -12.2 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_2589 -4.3 -13.8 3-isopropylmalate dehydrogenase compare
Psest_3649 -4.2 -9.0 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0280 -4.2 -16.3 homoserine O-acetyltransferase compare
Psest_0063 -4.1 -6.9 tryptophan synthase, beta subunit compare
Psest_1473 -4.1 -10.6 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0498 -4.0 -2.3 ribosome small subunit-dependent GTPase A compare
Psest_1452 -4.0 -8.4 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_4084 -3.9 -16.9 oxaloacetate decarboxylase alpha subunit compare
Psest_3810 -3.8 -2.6 orotate phosphoribosyltransferase compare
Psest_1772 -3.8 -5.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0411 -3.8 -11.9 biotin synthetase compare
Psest_2316 -3.8 -17.5 phosphoenolpyruvate synthase compare
Psest_4085 -3.8 -16.5 Biotin carboxylase compare
Psest_2590 -3.8 -1.9 3-isopropylmalate dehydratase, small subunit compare
Psest_0687 -3.7 -8.7 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_0489 -3.7 -2.5 phosphoserine phosphatase SerB compare
Psest_1474 -3.6 -5.0 phosphoribosylaminoimidazole synthetase compare
Psest_1013 -3.6 -3.5 phosphoribosylamine--glycine ligase compare
Psest_3818 -3.5 -7.8 endoribonuclease L-PSP, putative compare
Psest_0325 -3.5 -16.0 Putative threonine efflux protein compare
Psest_3145 -3.5 -2.1 hypothetical protein compare
Psest_1686 -3.5 -6.6 fatty acid/phospholipid synthesis protein PlsX compare
Psest_3322 -3.3 -20.1 TIGR02099 family protein compare
Psest_1837 -3.3 -10.0 Endoglucanase compare
Psest_0310 -3.3 -2.3 The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family compare
Psest_3297 -3.3 -12.5 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_3159 -3.3 -9.3 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_0536 -3.3 -3.2 thiamine-phosphate pyrophosphorylase compare
Psest_2945 -3.2 -2.9 septum site-determining protein MinC compare
Psest_4086 -3.1 -10.9 Transcriptional regulator compare
Psest_0412 -3.1 -12.3 8-amino-7-oxononanoate synthase compare
Psest_0951 -3.1 -12.1 FAD/FMN-containing dehydrogenases compare
Psest_0415 -3.0 -6.0 dethiobiotin synthase compare
Psest_3910 -3.0 -2.1 Uncharacterized protein conserved in bacteria compare
Psest_3721 -3.0 -8.9 Malic enzyme compare
Psest_0413 -3.0 -9.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_2104 -3.0 -3.5 IscR-regulated protein YhgI compare
Psest_0266 -2.9 -8.7 thiamine biosynthesis protein ThiS compare
Psest_0267 -2.9 -12.1 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_0013 -2.8 -8.7 Lauroyl/myristoyl acyltransferase compare
Psest_0306 -2.8 -15.0 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_3178 -2.8 -3.4 formyltetrahydrofolate deformylase compare
Psest_3494 -2.8 -1.9 hypothetical protein compare
Psest_0313 -2.7 -3.7 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_1814 -2.7 -17.6 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_3177 -2.7 -2.4 hypothetical protein compare
Psest_3123 -2.7 -5.1 dihydroorotase, homodimeric type compare
Psest_0955 -2.7 -6.8 D,L-lactate:H+ symporter (from data) compare
Psest_0442 -2.7 -6.9 ATPases of the AAA+ class compare
Psest_4243 -2.7 -1.8 type VI secretion lipoprotein, VC_A0113 family compare
Psest_1527 -2.6 -13.2 Na+/proline symporter compare
Psest_2946 -2.6 -6.7 septum site-determining protein MinD compare
Psest_2329 -2.6 -14.7 Transcriptional regulator compare
Psest_1511 -2.6 -5.3 Predicted redox protein, regulator of disulfide bond formation compare
Psest_2120 -2.6 -2.4 Transcriptional regulator compare
Psest_1704 -2.5 -3.4 Dehydrogenases (flavoproteins) compare
Psest_3338 -2.5 -2.4 Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain compare
Psest_0359 -2.5 -2.4 Transcriptional regulators compare
Psest_2067 -2.5 -2.2 ABC-type oligopeptide transport system, periplasmic component compare
Psest_0309 -2.5 -1.4 RND family efflux transporter, MFP subunit compare
Psest_3185 -2.5 -2.8 MoxR-like ATPases compare
Psest_3943 -2.4 -4.0 Phosphoribosyl-AMP cyclohydrolase compare
Psest_2988 -2.4 -7.3 aspartate kinase, monofunctional class compare
Psest_3565 -2.4 -2.4 hypothetical protein compare
Psest_0477 -2.4 -12.6 thiamine biosynthesis protein ThiC compare
Psest_3301 -2.4 -2.9 Predicted transcriptional regulator, BolA superfamily compare
Psest_1115 -2.4 -3.9 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_0078 -2.4 -1.2 hypothetical protein compare
Psest_2066 -2.4 -2.5 ABC-type uncharacterized transport system, permease component compare
Psest_1947 -2.3 -2.3 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_1496 -2.3 -2.3 Holliday junction DNA helicase, RuvA subunit compare
Psest_1292 -2.3 -8.9 monothiol glutaredoxin, Grx4 family compare
Psest_0277 -2.3 -2.0 non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family compare
Psest_1031 -2.2 -8.1 Uncharacterized protein conserved in bacteria compare
Psest_3092 -2.2 -2.9 ribonuclease III, bacterial compare
Psest_1080 -2.2 -7.3 Acetyl/propionyl-CoA carboxylase, alpha subunit compare
Psest_0719 -2.2 -6.3 Uncharacterized protein conserved in bacteria compare
Psest_0367 -2.2 -2.1 Predicted branched-chain amino acid permease (azaleucine resistance) compare
Psest_1083 -2.1 -7.7 3-methylcrotonyl-CoA carboxylase, beta subunit (EC 6.4.1.4) (from data) compare
Psest_1056 -2.1 -2.7 2-isopropylmalate synthase, bacterial type compare
Psest_3732 -2.1 -7.9 polyphosphate kinase 1 compare
Psest_4323 -2.0 -11.2 Predicted acyltransferases compare
Psest_3550 -2.0 -2.1 3,4-dihydroxy-2-butanone 4-phosphate synthase compare
Psest_1804 -2.0 -3.5 Superfamily II DNA and RNA helicases compare
Psest_4098 -2.0 -3.0 Superfamily I DNA and RNA helicases compare
Psest_3128 -2.0 -4.1 Protein-disulfide isomerase compare
Psest_3148 -2.0 -2.2 hypothetical protein compare
Psest_0722 -1.9 -8.3 Predicted ATPase compare
Psest_2532 -1.9 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_3031 -1.9 -1.1 hypothetical protein compare
Psest_3749 -1.9 -10.2 Response regulator of the LytR/AlgR family compare
Psest_2531 -1.9 -11.2 cytochrome c oxidase accessory protein FixG compare
Psest_3496 -1.9 -1.3 Predicted metal-binding protein compare
Psest_4142 -1.9 -1.5 hypothetical protein compare
Psest_0958 -1.8 -6.8 Oligoketide cyclase/lipid transport protein compare
Psest_2719 -1.8 -4.6 acetylornithine and succinylornithine aminotransferases/succinylornithine transaminase family compare
Psest_3720 -1.8 -12.6 penicillin-binding protein, 1A family compare
Psest_1012 -1.8 -5.7 Signal transduction histidine kinase compare
Psest_2001 -1.8 -2.0 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_1075 -1.8 -3.9 Predicted transcriptional regulators compare
Psest_3546 -1.7 -1.1 Phosphatidylglycerophosphatase A and related proteins compare
Psest_0349 -1.7 -4.5 DNA polymerase III, alpha subunit (gram-positive type) compare
Psest_0311 -1.7 -4.2 efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family compare
Psest_1999 -1.7 -1.8 pseudouridine synthase compare
Psest_0414 -1.7 -4.6 biotin biosynthesis protein BioC compare
Psest_3862 -1.7 -9.6 phosphoenolpyruvate-protein phosphotransferase compare
Psest_0368 -1.7 -1.4 Transcriptional regulator compare
Psest_3377 -1.7 -1.4 FKBP-type peptidyl-prolyl cis-trans isomerases 2 compare
Psest_0347 -1.7 -10.4 large component of pyruvate/D-alanine transporter (actP-like) (from data) compare
Psest_1884 -1.7 -2.6 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_0514 -1.6 -5.3 lytic murein transglycosylase B compare
Psest_4103 -1.6 -1.5 AraC-type DNA-binding domain-containing proteins compare
Psest_1510 -1.6 -3.4 Putative Zn-dependent protease, contains TPR repeats compare
Psest_1840 -1.6 -12.8 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_0959 -1.5 -2.6 Uncharacterized protein conserved in bacteria compare
Psest_1498 -1.5 -2.0 tol-pal system-associated acyl-CoA thioesterase compare
Psest_0691 -1.5 -8.5 ribonuclease R compare
Psest_1640 -1.5 -7.1 (p)ppGpp synthetase, RelA/SpoT family compare
Psest_1122 -1.5 -10.7 putative adhesin (DUF1302) (from data) compare
Psest_3762 -1.5 -3.9 iron donor protein CyaY compare
Psest_0257 -1.5 -2.3 Predicted Zn-dependent peptidases compare
Psest_1293 -1.4 -1.6 VanZ like family. compare
Psest_1923 -1.4 -3.0 adhesin-associated BNR repeat protein (from data) compare
Psest_2136 -1.4 -5.0 Predicted homoserine dehydrogenase compare
Psest_2331 -1.4 -6.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
Psest_0298 -1.4 -4.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
Psest_2643 -1.4 -1.3 Beta-glucosidase-related glycosidases compare
Psest_0292 -1.4 -2.5 Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase compare
Psest_2646 -1.4 -2.6 SOS regulatory protein LexA compare
Psest_3101 -1.4 -8.3 L-aspartate oxidase compare
Psest_2018 -1.3 -2.4 Uncharacterized conserved protein compare
Psest_0170 -1.3 -5.6 5,10-methenyltetrahydrofolate synthetase compare
Psest_3112 -1.3 -3.6 electron transport complex, RnfABCDGE type, A subunit compare
Psest_4310 -1.3 -1.5 ABC-type Mn2+/Zn2+ transport systems, permease components compare
Psest_3998 -1.3 -5.2 glutamate--cysteine ligase compare
Psest_2938 -1.3 -9.3 transporter, SSS family compare
Psest_3323 -1.3 -3.3 ribonuclease, Rne/Rng family compare
Psest_3637 -1.3 -1.2 Predicted molecular chaperone distantly related to HSP70-fold metalloproteases compare
Psest_4307 -1.3 -1.8 ABC-type Zn2+ transport system, periplasmic component/surface adhesin compare
Psest_1144 -1.3 -1.5 AmpG-related permease compare
Psest_2585 -1.3 -1.3 pseudouridylate synthase I compare
Psest_2520 -1.3 -1.5 Predicted SAM-dependent methyltransferase compare
Psest_2090 -1.3 -3.3 Protein of unknown function (DUF2970). compare
Psest_1132 -1.3 -2.8 mutator mutT protein compare
Psest_0521 -1.3 -6.7 lytic murein transglycosylase compare
Psest_1819 -1.3 -10.2 Nucleoside-diphosphate-sugar epimerases compare
Psest_2718 -1.2 -0.8 hypothetical protein compare
Psest_0218 -1.2 -2.8 Acyl-CoA hydrolase compare
Psest_1480 -1.2 -1.9 arsenate reductase (glutaredoxin) compare
Psest_3934 -1.2 -3.1 rRNA methylase, putative, group 2 compare
Psest_2285 -1.2 -2.8 ATP-dependent protease La compare
Psest_1277 -1.2 -7.3 2-isopropylmalate synthase, yeast type compare
Psest_2545 -1.2 -2.4 recombination protein RecR compare
Psest_2530 -1.2 -4.6 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_1082 -1.2 -1.0 Enoyl-CoA hydratase/carnithine racemase compare
Psest_1557 -1.2 -4.5 Phosphoenolpyruvate carboxylase compare
Psest_1479 -1.2 -3.1 NAD(P)H:quinone oxidoreductase, type IV compare
Psest_0993 -1.1 -6.6 Glucose-6-phosphate isomerase compare
Psest_4256 -1.1 -1.3 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_2863 -1.1 -4.5 Transcriptional regulator compare
Psest_2000 -1.1 -3.3 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) compare
Psest_4184 -1.1 -3.4 hypothetical protein compare
Psest_2379 -1.1 -5.2 PAS domain S-box compare
Psest_2317 -1.1 -5.3 Uncharacterized protein conserved in bacteria compare
Psest_3296 -1.1 -3.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_3464 -1.1 -5.6 Signal transduction histidine kinase compare
Psest_4363 -1.1 -4.5 ATPases involved in chromosome partitioning compare
Psest_0174 -1.1 -3.6 Uncharacterized protein conserved in bacteria compare
Psest_3113 -1.1 -1.8 electron transport complex, RnfABCDGE type, B subunit compare


Specific Phenotypes

For 5 genes in this experiment

For stress Cephalothin sodium salt in Pseudomonas stutzeri RCH2

For stress Cephalothin sodium salt across organisms