Experiment set7H1 for Pseudomonas stutzeri RCH2

Compare to:

RCH2 defined media with Phosphomycin disodium salt 0.125 mg/ml

200 most important genes:

  gene name fitness t score description  
Psest_2584 -5.3 -7.3 Phosphoribosylanthranilate isomerase compare
Psest_2589 -4.8 -12.4 3-isopropylmalate dehydrogenase compare
Psest_3384 -4.8 -8.6 glutamate 5-kinase compare
Psest_3648 -4.7 -5.6 anthranilate phosphoribosyltransferase compare
Psest_3298 -4.7 -9.6 histidinol dehydrogenase compare
Psest_3647 -4.7 -7.1 Indole-3-glycerol phosphate synthase compare
Psest_0153 -4.7 -12.1 imidazole glycerol phosphate synthase, glutamine amidotransferase subunit compare
Psest_0954 -4.6 -10.6 Fe-S oxidoreductase compare
Psest_0155 -4.6 -5.5 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase (EC 5.3.1.16) (from data) compare
Psest_2591 -4.6 -4.5 3-isopropylmalate dehydratase, large subunit compare
Psest_0325 -4.5 -14.7 Putative threonine efflux protein compare
Psest_0062 -4.4 -6.7 tryptophan synthase, alpha subunit compare
Psest_3299 -4.4 -12.9 ATP phosphoribosyltransferase (EC 2.4.2.17) (from data) compare
Psest_0326 -4.4 -14.5 Taurine catabolism dioxygenase TauD, TfdA family. compare
Psest_2578 -4.4 -14.9 O-succinylhomoserine sulfhydrylase compare
Psest_3864 -4.3 -13.1 Histidinol-phosphatase (EC:3.1.3.15) (from data) compare
Psest_3650 -4.3 -11.5 anthranilate synthase component I, non-proteobacterial lineages compare
Psest_2579 -4.3 -8.7 amidophosphoribosyltransferase compare
Psest_3866 -4.2 -15.7 threonine ammonia-lyase, biosynthetic, long form compare
Psest_0952 -4.1 -4.9 Uncharacterized conserved protein compare
Psest_0508 -4.0 -8.6 gamma-glutamyl phosphate reductase compare
Psest_3159 -4.0 -9.7 phosphoribosylformylglycinamidine synthase, single chain form compare
Psest_1452 -4.0 -8.5 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase compare
Psest_0279 -3.9 -6.6 methionine biosynthesis protein MetW compare
Psest_1772 -3.9 -5.9 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_0152 -3.8 -7.2 Imidazoleglycerol-phosphate dehydratase compare
Psest_0280 -3.8 -13.6 homoserine O-acetyltransferase compare
Psest_0687 -3.7 -9.2 ATP phosphoribosyltransferase, regulatory subunit compare
Psest_3649 -3.7 -8.6 glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase compare
Psest_0063 -3.7 -6.1 tryptophan synthase, beta subunit compare
Psest_0489 -3.5 -2.4 phosphoserine phosphatase SerB compare
Psest_1013 -3.5 -4.1 phosphoribosylamine--glycine ligase compare
Psest_3810 -3.5 -2.4 orotate phosphoribosyltransferase compare
Psest_1474 -3.5 -5.3 phosphoribosylaminoimidazole synthetase compare
Psest_3226 -3.4 -2.3 Predicted membrane protein compare
Psest_1295 -3.3 -8.8 Aspartate/tyrosine/aromatic aminotransferase compare
Psest_2316 -3.3 -16.9 phosphoenolpyruvate synthase compare
Psest_0414 -3.3 -6.2 biotin biosynthesis protein BioC compare
Psest_2232 -3.2 -16.5 UTP-glucose-1-phosphate uridylyltransferase compare
Psest_3818 -3.2 -7.6 endoribonuclease L-PSP, putative compare
Psest_1473 -3.1 -10.3 phosphoribosylglycinamide formyltransferase, formyltetrahydrofolate-dependent compare
Psest_0953 -3.1 -12.2 iron-sulfur cluster-binding protein compare
Psest_2590 -3.1 -2.5 3-isopropylmalate dehydratase, small subunit compare
Psest_3296 -3.1 -2.1 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
Psest_3100 -3.0 -9.8 RNA polymerase sigma factor RpoE compare
Psest_3297 -3.0 -12.0 histidinol-phosphate aminotransferase (EC 2.6.1.9) (from data) compare
Psest_4084 -3.0 -15.3 oxaloacetate decarboxylase alpha subunit compare
Psest_1509 -3.0 -9.5 quinolinate synthetase complex, A subunit compare
Psest_0466 -3.0 -5.9 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_3721 -3.0 -8.8 Malic enzyme compare
Psest_4085 -2.9 -14.2 Biotin carboxylase compare
Psest_0993 -2.9 -12.5 Glucose-6-phosphate isomerase compare
Psest_2088 -2.9 -4.7 Uncharacterized protein conserved in bacteria compare
Psest_0415 -2.8 -5.2 dethiobiotin synthase compare
Psest_3944 -2.7 -2.6 phosphoribosyl-ATP pyrophosphatase (EC 3.6.1.31) (from data) compare
Psest_0411 -2.7 -10.6 biotin synthetase compare
Psest_1037 -2.7 -4.4 acetolactate synthase, small subunit compare
Psest_4086 -2.7 -11.6 Transcriptional regulator compare
Psest_2066 -2.7 -5.2 ABC-type uncharacterized transport system, permease component compare
Psest_1947 -2.6 -2.5 dihydroorotate dehydrogenase, subfamily 2 compare
Psest_3123 -2.6 -4.8 dihydroorotase, homodimeric type compare
Psest_3910 -2.5 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_3322 -2.5 -17.9 TIGR02099 family protein compare
Psest_0536 -2.5 -3.8 thiamine-phosphate pyrophosphorylase compare
Psest_0013 -2.5 -7.2 Lauroyl/myristoyl acyltransferase compare
Psest_0718 -2.5 -3.8 nicotinate-nucleotide pyrophosphorylase compare
Psest_0313 -2.5 -2.9 5,10-methylenetetrahydrofolate reductase, prokaryotic form compare
Psest_3456 -2.4 -1.8 RNA polymerase sigma factor, sigma-70 family compare
Psest_2945 -2.4 -3.2 septum site-determining protein MinC compare
Psest_0999 -2.4 -4.2 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains compare
Psest_0385 -2.4 -2.2 Conserved secreted protein compare
Psest_0417 -2.4 -4.7 Acyl-CoA dehydrogenases compare
Psest_3449 -2.4 -1.6 DJ-1 family protein compare
Psest_1012 -2.4 -6.3 Signal transduction histidine kinase compare
Psest_4103 -2.3 -2.2 AraC-type DNA-binding domain-containing proteins compare
Psest_0412 -2.3 -10.1 8-amino-7-oxononanoate synthase compare
Psest_3555 -2.3 -3.1 Predicted methyltransferase compare
Psest_1424 -2.3 -2.1 Lipoate-protein ligase A compare
Psest_3301 -2.2 -5.0 Predicted transcriptional regulator, BolA superfamily compare
Psest_2988 -2.2 -7.9 aspartate kinase, monofunctional class compare
Psest_0170 -2.1 -6.0 5,10-methenyltetrahydrofolate synthetase compare
Psest_0306 -2.0 -12.5 adenosylmethionine-8-amino-7-oxononanoate transaminase compare
Psest_1704 -2.0 -3.2 Dehydrogenases (flavoproteins) compare
Psest_1837 -2.0 -9.0 Endoglucanase compare
Psest_3270 -2.0 -3.4 probable S-adenosylmethionine-dependent methyltransferase, YraL family compare
Psest_0359 -1.9 -2.9 Transcriptional regulators compare
Psest_0191 -1.9 -1.0 PAS domain S-box compare
Psest_3316 -1.9 -8.1 Predicted P-loop-containing kinase compare
Psest_0413 -1.8 -6.1 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
Psest_1824 -1.8 -4.1 Sugar transferases involved in lipopolysaccharide synthesis compare
Psest_3174 -1.7 -13.5 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase compare
Psest_0389 -1.7 -2.3 hypothetical protein compare
Psest_3960 -1.7 -2.3 3'(2'),5'-bisphosphate nucleotidase, bacterial compare
Psest_3896 -1.7 -1.9 arsenite-activated ATPase ArsA compare
Psest_0212 -1.7 -1.5 exodeoxyribonuclease V, gamma subunit compare
Psest_3002 -1.6 -1.8 Putative translation initiation inhibitor, yjgF family compare
Psest_1840 -1.6 -14.4 Undecaprenyl-phosphate glucose phosphotransferase compare
Psest_0951 -1.6 -8.3 FAD/FMN-containing dehydrogenases compare
Psest_1819 -1.6 -14.3 Nucleoside-diphosphate-sugar epimerases compare
Psest_0955 -1.6 -5.5 D,L-lactate:H+ symporter (from data) compare
Psest_3943 -1.6 -3.0 Phosphoribosyl-AMP cyclohydrolase compare
Psest_0717 -1.6 -11.3 Protein of unknown function (DUF1631). compare
Psest_2643 -1.6 -1.5 Beta-glucosidase-related glycosidases compare
Psest_0064 -1.6 -1.1 Transcriptional regulator compare
Psest_2944 -1.6 -2.7 lipid A biosynthesis lauroyl (or palmitoleoyl) acyltransferase compare
Psest_4191 -1.6 -1.1 Transcriptional regulator compare
Psest_0477 -1.6 -9.3 thiamine biosynthesis protein ThiC compare
Psest_3565 -1.6 -2.0 hypothetical protein compare
Psest_4256 -1.6 -1.8 ABC-type transport system involved in resistance to organic solvents, ATPase component compare
Psest_3502 -1.6 -2.5 flavoprotein, HI0933 family/uncharacterized flavoprotein, PP_4765 family compare
Psest_3988 -1.5 -5.5 phosphoenolpyruvate carboxykinase (ATP) compare
Psest_0487 -1.5 -3.7 Uncharacterized protein conserved in bacteria compare
Psest_1144 -1.5 -1.8 AmpG-related permease compare
Psest_3894 -1.5 -3.0 Carbon starvation protein, predicted membrane protein compare
Psest_0725 -1.5 -2.4 Negative regulator of beta-lactamase expression compare
Psest_2243 -1.5 -1.9 glyceraldehyde-3-phosphate dehydrogenase, type I compare
Psest_3700 -1.5 -0.6 hypothetical protein compare
Psest_3790 -1.5 -5.9 Cytochrome c5 compare
Psest_2329 -1.5 -10.5 Transcriptional regulator compare
Psest_2050 -1.5 -8.1 Arabinose efflux permease compare
Psest_3092 -1.5 -2.6 ribonuclease III, bacterial compare
Psest_0368 -1.5 -1.9 Transcriptional regulator compare
Psest_2527 -1.4 -7.4 cytochrome c oxidase, cbb3-type, subunit I compare
Psest_2946 -1.4 -4.4 septum site-determining protein MinD compare
Psest_0267 -1.4 -8.3 Uncharacterized enzyme of thiazole biosynthesis compare
Psest_1656 -1.4 -3.3 NADH:ubiquinone oxidoreductase, Na(+)-translocating, B subunit compare
Psest_1657 -1.4 -2.8 NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit compare
Psest_2001 -1.4 -2.2 2-phosphoglycolate phosphatase, prokaryotic compare
Psest_3448 -1.4 -3.9 Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family compare
Psest_0722 -1.4 -6.6 Predicted ATPase compare
Psest_0327 -1.4 -5.2 Transcriptional regulator compare
Psest_2532 -1.4 -3.4 Uncharacterized protein conserved in bacteria compare
Psest_1180 -1.4 -4.0 hydroxypyruvate isomerase compare
Psest_0030 -1.4 -1.8 Putative NADH-flavin reductase compare
Psest_1115 -1.3 -3.0 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 compare
Psest_1814 -1.3 -9.4 pseudaminic acid biosynthesis N-acetyl transferase compare
Psest_2764 -1.3 -1.8 hypothetical protein compare
Psest_0266 -1.3 -4.8 thiamine biosynthesis protein ThiS compare
Psest_3893 -1.3 -2.5 Multisubunit Na+/H+ antiporter, MnhE subunit compare
Psest_2862 -1.3 -7.9 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 compare
Psest_3117 -1.3 -4.5 electron transport complex, RnfABCDGE type, E subunit compare
Psest_2090 -1.3 -3.6 Protein of unknown function (DUF2970). compare
Psest_4219 -1.3 -2.0 DNA polymerase I compare
Psest_2360 -1.2 -2.6 Uncharacterized protein, putative amidase compare
Psest_1070 -1.2 -2.5 Predicted membrane protein compare
Psest_3899 -1.2 -2.6 Predicted phosphoribosyltransferases compare
Psest_1354 -1.2 -1.3 Uncharacterized protein conserved in bacteria compare
Psest_3962 -1.2 -1.5 haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED compare
Psest_3355 -1.2 -2.9 fructose-specific PTS system (fructose 1-phosphate forming), EI, Hpr, and EII-A components (from data) compare
Psest_0537 -1.2 -1.3 Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase compare
Psest_1022 -1.2 -6.5 Thiol:disulfide interchange protein compare
Psest_3128 -1.2 -3.7 Protein-disulfide isomerase compare
Psest_1809 -1.2 -7.1 Membrane protein involved in the export of O-antigen and teichoic acid compare
Psest_1686 -1.2 -4.5 fatty acid/phospholipid synthesis protein PlsX compare
Psest_2530 -1.2 -4.4 cytochrome c oxidase, cbb3-type, subunit III compare
Psest_2651 -1.2 -3.6 DNA topoisomerase I, bacterial compare
Psest_0716 -1.2 -1.4 Protein of unknown function (DUF3094). compare
Psest_1366 -1.1 -0.9 hypothetical protein compare
Psest_2566 -1.1 -1.2 Uncharacterized protein conserved in bacteria compare
Psest_3832 -1.1 -1.2 hypothetical protein compare
Psest_2531 -1.1 -8.1 cytochrome c oxidase accessory protein FixG compare
Psest_3188 -1.1 -3.4 hypothetical protein compare
Psest_1661 -1.1 -2.7 Membrane-associated lipoprotein involved in thiamine biosynthesis compare
Psest_4146 -1.1 -3.0 Flagellar basal-body P-ring protein compare
Psest_0457 -1.1 -3.0 Lipopolysaccharide kinase (Kdo/WaaP) family. compare
Psest_0740 -1.1 -1.7 Transcriptional regulator compare
Psest_3998 -1.1 -4.1 glutamate--cysteine ligase compare
Psest_0032 -1.1 -5.5 D-alanyl-D-alanine carboxypeptidase compare
Psest_2317 -1.1 -4.0 Uncharacterized protein conserved in bacteria conserved
Psest_2413 -1.1 -1.6 Periplasmic protein TonB, links inner and outer membranes compare
Psest_2646 -1.1 -2.6 SOS regulatory protein LexA compare
Psest_0226 -1.1 -1.5 Domain of unknown function (DUF3482)./GTPase of unknown function. compare
Psest_3047 -1.0 -1.6 methionyl-tRNA synthetase/methionyl-tRNA synthetase C-terminal region/beta chain compare
Psest_1238 -1.0 -5.3 Predicted membrane protein/domain compare
Psest_1924 -1.0 -7.5 adhesin-associated MmpL efflux pump (from data) compare
Psest_2121 -1.0 -3.5 Predicted ATPase compare
Psest_2864 -1.0 -3.9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain compare
Psest_4271 -1.0 -2.7 Predicted proline hydroxylase compare
Psest_1873 -1.0 -3.9 Predicted permease, DMT superfamily compare
Psest_0730 -1.0 -3.2 O-6-methylguanine DNA methyltransferase compare
Psest_0201 -1.0 -2.2 PAS domain S-box compare
Psest_0575 -1.0 -0.8 HrpA-like helicases compare
Psest_0040 -1.0 -3.4 Protein of unknown function (DUF2934). compare
Psest_3087 -1.0 -4.1 Transcriptional regulator compare
Psest_4054 -1.0 -2.0 alkanesulfonate monooxygenase, FMNH(2)-dependent compare
Psest_2104 -1.0 -2.4 IscR-regulated protein YhgI compare
Psest_1031 -1.0 -4.8 Uncharacterized protein conserved in bacteria compare
Psest_1516 -1.0 -2.2 Uncharacterized lipoprotein compare
Psest_0041 -1.0 -2.4 Uncharacterized protein conserved in bacteria compare
Psest_2888 -1.0 -3.2 Transcriptional activator of acetoin/glycerol metabolism compare
Psest_1511 -1.0 -3.4 Predicted redox protein, regulator of disulfide bond formation compare
Psest_1071 -1.0 -2.8 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains compare
Psest_3455 -1.0 -1.8 Dihaem cytochrome c. compare
Psest_3839 -1.0 -2.3 D-lactate/glycolate dehydrogenase, iron-sulfur subunit GlcF (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_3012 -1.0 -1.9 cob(II)yrinic acid a,c-diamide reductase compare
Psest_0346 -1.0 -1.4 small component of pyruvate/D-alanine transporter (TIGR03647) (from data) compare
Psest_1087 -1.0 -1.0 uncharacterized peroxidase-related enzyme compare
Psest_3840 -0.9 -2.7 D-lactate/glycolate dehydrogenase, FAD binding subunit GlcE (EC 1.1.99.6; EC 1.1.99.14) (from data) compare
Psest_3115 -0.9 -5.1 electron transport complex, RnfABCDGE type, D subunit compare
Psest_4004 -0.9 -1.4 Uncharacterized conserved protein compare


Specific Phenotypes

For 3 genes in this experiment

For stress Phosphomycin disodium salt in Pseudomonas stutzeri RCH2

For stress Phosphomycin disodium salt across organisms