Experiment set6IT094 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM D-Alanine

200 most important genes:

  gene name fitness t score description  
MMP_RS03450 -6.5 -3.0 glycine synthesis protein GlyXS (from data) compare
MMP_RS07345 -4.9 -8.7 glycine synthesis protein GlyXL (from data) compare
MMP_RS01545 -4.8 -1.3 CBS domain-containing protein compare
MMP_RS03315 -4.7 -1.6 ferrous iron transport protein A compare
MMP_RS01385 -4.4 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06475 -4.3 -7.0 FAD-dependent oxidoreductase compare
MMP_RS05500 -4.2 -13.5 2-isopropylmalate synthase compare
MMP_RS06355 -4.2 -3.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01175 -4.2 -5.4 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05920 -4.2 -0.8 50S ribosomal protein L37e compare
MMP_RS02900 -4.1 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS08165 -3.8 -3.3 phosphoglycerate dehydrogenase compare
MMP_RS06350 -3.7 -9.6 HesA/MoeB/ThiF family protein compare
MMP_RS07775 -3.7 -6.5 alanine dehydrogenase compare
MMP_RS04605 -3.7 -6.9 cobalt ECF transporter T component CbiQ compare
MMP_RS03435 -3.7 -2.6 ketol-acid reductoisomerase compare
MMP_RS03035 -3.7 -5.5 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03700 -3.7 -12.6 sodium:proton antiporter compare
MMP_RS07635 -3.6 -9.0 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08210 -3.6 -3.3 phosphatidylglycerophosphatase A compare
MMP_RS02145 -3.6 -12.9 winged helix-turn-helix transcriptional regulator compare
MMP_RS06375 -3.6 -7.5 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS01455 -3.6 -8.8 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS08720 -3.5 -2.6 4Fe-4S binding protein compare
MMP_RS01020 -3.5 -1.3 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS04215 -3.5 -8.9 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS04710 -3.5 -2.5 hypothetical protein compare
MMP_RS03015 -3.5 -10.5 GTP 3' 8-cyclase MoaA compare
MMP_RS05515 -3.4 -7.7 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04615 -3.4 -5.1 PDGLE domain-containing protein compare
MMP_RS02010 -3.4 -14.2 PHP domain-containing protein compare
MMP_RS05510 -3.4 -10.0 Rrf2 family transcriptional regulator compare
MMP_RS06270 -3.4 -9.1 TIGR00300 family protein compare
MMP_RS02280 -3.3 -1.2 DUF211 domain-containing protein compare
MMP_RS03475 -3.3 -0.9 hypothetical protein compare
MMP_RS07525 -3.3 -8.3 4Fe-4S binding protein compare
MMP_RS07770 -3.3 -12.2 alanine racemase conserved
MMP_RS01325 -3.2 -2.8 dihydroneopterin aldolase family protein compare
MMP_RS00040 -3.2 -6.6 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07005 -3.2 -0.8 4Fe-4S binding protein compare
MMP_RS02240 -3.2 -4.4 methanogenesis marker 7 protein compare
MMP_RS03600 -3.2 -3.4 triose-phosphate isomerase compare
MMP_RS06400 -3.1 -2.4 4Fe-4S binding protein compare
MMP_RS06120 -3.1 -2.8 UPF0147 family protein compare
MMP_RS08745 -3.1 -7.4 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS08715 -3.1 -2.5 formylmethanofuran dehydrogenase subunit B compare
MMP_RS07845 -3.1 -3.2 LL-diaminopimelate aminotransferase compare
MMP_RS07355 -3.0 -1.4 transcription factor S compare
MMP_RS07365 -3.0 -15.7 2-phosphoglycerate kinase compare
MMP_RS01830 -3.0 -2.3 tRNA-Val compare
MMP_RS06295 -3.0 -9.1 methanogenesis marker 14 protein compare
MMP_RS00915 -3.0 -9.8 DUF116 domain-containing protein compare
MMP_RS04900 -3.0 -20.5 hypothetical protein compare
MMP_RS01755 -3.0 -1.6 DUF2097 domain-containing protein compare
MMP_RS04620 -2.9 -13.7 cobalt transporter CbiM compare
MMP_RS07765 -2.9 -9.8 sodium:alanine symporter family protein compare
MMP_RS07075 -2.9 -6.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS01610 -2.9 -4.6 hypothetical protein compare
MMP_RS04790 -2.9 -13.7 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS00300 -2.8 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06885 -2.8 -3.1 50S ribosome-binding GTPase compare
MMP_RS07435 -2.8 -2.3 GMP synthase subunit A compare
MMP_RS01800 -2.8 -4.9 TIGR00303 family protein compare
MMP_RS06370 -2.7 -6.2 biotin synthase BioB compare
MMP_RS04585 -2.7 -12.3 AIR synthase related protein compare
MMP_RS00110 -2.7 -3.0 hypothetical protein compare
MMP_RS05930 -2.7 -3.1 3-isopropylmalate dehydratase large subunit compare
MMP_RS08650 -2.6 -4.5 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01005 -2.6 -1.7 riboflavin synthase compare
MMP_RS05845 -2.6 -2.1 tRNA-intron lyase compare
MMP_RS01500 -2.6 -3.6 CBS domain-containing protein compare
MMP_RS02135 -2.6 -7.4 DUF5612 domain-containing protein compare
MMP_RS02355 -2.6 -4.1 30S ribosomal protein S27ae compare
MMP_RS03640 -2.5 -4.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS00750 -2.5 -3.0 fumarate hydratase compare
MMP_RS00455 -2.5 -8.5 orotate phosphoribosyltransferase-like protein compare
MMP_RS04500 -2.5 -16.1 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS02195 -2.5 -5.4 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS08300 -2.5 -1.4 metal-sulfur cluster assembly factor compare
MMP_RS01265 -2.4 -2.5 hypothetical protein compare
MMP_RS05250 -2.4 -1.9 NFYB/HAP3 family transcription factor subunit compare
MMP_RS08790 -2.4 -2.7 translation initiation factor IF-2 subunit alpha compare
MMP_RS04685 -2.4 -3.8 DUF126 domain-containing protein compare
MMP_RS03440 -2.4 -1.6 MoaD/ThiS family protein compare
MMP_RS08500 -2.3 -6.1 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS00305 -2.3 -2.5 phosphoribosyl-ATP diphosphatase compare
MMP_RS01220 -2.3 -9.0 hypothetical protein compare
MMP_RS03580 -2.3 -4.9 signal recognition particle-docking protein FtsY compare
MMP_RS07630 -2.3 -2.0 ATP-binding cassette domain-containing protein compare
MMP_RS05815 -2.3 -2.5 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01795 -2.3 -2.3 methanogenesis marker 6 protein compare
MMP_RS01225 -2.3 -7.3 DUF5379 domain-containing protein compare
MMP_RS07605 -2.3 -5.0 diadenylate cyclase compare
MMP_RS08095 -2.2 -8.3 dethiobiotin synthase compare
MMP_RS07445 -2.2 -4.9 helix-turn-helix domain-containing protein compare
MMP_RS05925 -2.2 -4.7 small nuclear ribonucleoprotein compare
MMP_RS06315 -2.2 -1.1 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS03025 -2.2 -5.4 molybdenum cofactor guanylyltransferase compare
MMP_RS02245 -2.1 -3.9 hypothetical protein compare
MMP_RS03960 -2.1 -1.3 hypothetical protein compare
MMP_RS00685 -2.1 -3.6 2-phospho-L-lactate guanylyltransferase compare
MMP_RS07390 -2.1 -2.9 cell division protein FtsZ compare
MMP_RS01375 -2.1 -12.7 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS06625 -2.1 -2.1 DNA primase compare
MMP_RS05285 -2.1 -9.5 MMPL family transporter compare
MMP_RS04775 -2.1 -4.0 adenosylhomocysteinase compare
MMP_RS08435 -2.1 -2.5 Era-like GTP-binding protein compare
MMP_RS00895 -2.1 -5.0 hypothetical protein compare
MMP_RS00985 -2.0 -5.7 CDC48 family AAA ATPase compare
MMP_RS05265 -2.0 -2.8 2-isopropylmalate synthase compare
MMP_RS00310 -2.0 -6.0 CBS domain-containing protein compare
MMP_RS07600 -2.0 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01725 -2.0 -5.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS00515 -1.9 -1.1 DUF655 domain-containing protein compare
MMP_RS07955 -1.9 -5.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS07545 -1.9 -1.4 HTH domain-containing protein compare
MMP_RS06020 -1.9 -5.1 archaeoflavoprotein AfpA compare
MMP_RS08635 -1.8 -2.3 UbiA family prenyltransferase compare
MMP_RS02800 -1.8 -7.8 nucleotidyltransferase domain-containing protein compare
MMP_RS09020 -1.8 -1.8 hypothetical protein compare
MMP_RS06895 -1.8 -1.6 selenocysteine-specific translation elongation factor compare
MMP_RS03250 -1.8 -4.7 MJ1244 family protein compare
MMP_RS01380 -1.8 -4.4 PHP domain-containing protein compare
MMP_RS06285 -1.8 -2.1 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07420 -1.8 -6.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS08100 -1.8 -7.4 8-amino-7-oxononanoate synthase compare
MMP_RS08460 -1.8 -3.3 proteasome-activating nucleotidase compare
MMP_RS07200 -1.7 -6.1 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS07755 -1.7 -1.1 DUF555 domain-containing protein compare
MMP_RS08105 -1.7 -6.3 6-carboxyhexanoate--CoA ligase compare
MMP_RS05430 -1.7 -3.9 TIGR00288 family NYN domain-containing protein compare
MMP_RS06175 -1.7 -7.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07380 -1.7 -2.0 transcription elongation factor Spt5 compare
MMP_RS05280 -1.7 -10.8 COG1361 S-layer family protein compare
MMP_RS04780 -1.7 -2.9 ribonuclease P compare
MMP_RS00375 -1.7 -7.6 ammonium transporter compare
MMP_RS03445 -1.6 -1.1 methanogenesis marker 17 protein compare
MMP_RS06340 -1.6 -7.3 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS08820 -1.6 -5.2 hypothetical protein compare
MMP_RS07090 -1.6 -7.9 tRNA (adenine-N1)-methyltransferase compare
MMP_RS06730 -1.6 -1.4 phosphopantothenate/pantothenate synthetase compare
MMP_RS01700 -1.6 -1.1 dihydroxy-acid dehydratase compare
MMP_RS06925 -1.6 -2.3 ribonuclease VapC4 compare
MMP_RS08785 -1.6 -1.1 RNA-protein complex protein Nop10 compare
MMP_RS01905 -1.6 -10.2 glycosyltransferase compare
MMP_RS08440 -1.6 -2.2 cell division protein SepF compare
MMP_RS04955 -1.6 -5.8 DNA topoisomerase I compare
MMP_RS03095 -1.6 -6.7 diphthine synthase compare
MMP_RS01925 -1.6 -6.7 DUF1616 domain-containing protein compare
MMP_RS06725 -1.6 -8.7 hypothetical protein compare
MMP_RS01440 -1.5 -4.6 NAAT family transporter compare
MMP_RS05540 -1.5 -2.1 hypothetical protein compare
MMP_RS08760 -1.5 -1.4 hypothetical protein compare
MMP_RS04485 -1.5 -9.1 putative beta-lysine N-acetyltransferase compare
MMP_RS07685 -1.5 -7.0 TIGR01212 family radical SAM protein compare
MMP_RS06940 -1.5 -2.8 polyprenyl diphosphate synthase compare
MMP_RS06980 -1.5 -5.1 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS07750 -1.5 -3.8 DUF357 domain-containing protein compare
MMP_RS03390 -1.5 -5.9 malate dehydrogenase compare
MMP_RS05640 -1.5 -5.8 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00810 -1.4 -6.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS01900 -1.4 -8.9 hypothetical protein compare
MMP_RS07710 -1.4 -5.8 cell division protein FtsZ compare
MMP_RS06670 -1.4 -4.4 glucose-6-phosphate isomerase compare
MMP_RS04785 -1.4 -8.3 hypothetical protein compare
MMP_RS06855 -1.4 -5.8 hypothetical protein compare
MMP_RS01365 -1.4 -1.8 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07580 -1.4 -2.2 DUF356 domain-containing protein compare
MMP_RS00555 -1.4 -4.4 MFS transporter compare
MMP_RS00115 -1.4 -7.9 radical SAM protein compare
MMP_RS01975 -1.4 -10.2 hypothetical protein compare
MMP_RS01885 -1.3 -6.9 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS01840 -1.3 -7.0 TIGR00289 family protein compare
MMP_RS01875 -1.3 -6.4 N-acetyltransferase compare
MMP_RS08320 -1.3 -5.6 molybdopterin molybdotransferase MoeA compare
MMP_RS02345 -1.3 -2.8 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS05345 -1.3 -5.4 hypothetical protein compare
MMP_RS02875 -1.3 -6.3 chorismate pyruvate-lyase family protein compare
MMP_RS02930 -1.3 -1.8 class I SAM-dependent methyltransferase compare
MMP_RS03400 -1.3 -2.0 archease compare
MMP_RS00900 -1.3 -1.9 50S ribosomal protein L39e compare
MMP_RS00720 -1.3 -6.0 metal-dependent hydrolase compare
MMP_RS01880 -1.3 -4.7 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS06215 -1.3 -2.2 30S ribosomal protein S6e compare
MMP_RS03485 -1.3 -4.3 TIGR00267 family protein compare
MMP_RS06230 -1.2 -2.3 helix-turn-helix domain-containing protein compare
MMP_RS03080 -1.2 -1.5 universal stress protein compare
MMP_RS07645 -1.2 -3.8 aldehyde dehydrogenase family protein compare
MMP_RS05765 -1.2 -5.2 M42 family metallopeptidase compare
MMP_RS00695 -1.2 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04890 -1.2 -0.8 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03420 -1.2 -2.3 acetolactate synthase small subunit compare
MMP_RS07535 -1.2 -6.4 4Fe-4S binding protein compare
MMP_RS05440 -1.2 -6.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS01600 -1.2 -1.7 50S ribosomal protein L15e compare
MMP_RS06840 -1.2 -0.8 DNA-directed RNA polymerase subunit N compare
MMP_RS07575 -1.2 -2.2 RNA ligase partner protein compare
MMP_RS08195 -1.2 -5.0 hypothetical protein compare
MMP_RS08645 -1.2 -3.9 UPF0179 family protein compare
MMP_RS00320 -1.2 -1.4 class I SAM-dependent methyltransferase compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source D-Alanine in Methanococcus maripaludis S2

For nitrogen source D-Alanine across organisms