Experiment set6IT090 for Klebsiella michiganensis M5al

Compare to:

LB with Nickel (II) chloride hexahydrate 1.5 mM

200 most important genes:

  gene name fitness t score description  
BWI76_RS11260 -4.5 -2.4 hypothetical protein compare
BWI76_RS08605 -4.5 -3.7 phosphoglyceromutase compare
BWI76_RS27225 -4.3 -4.6 rhodanese-like domain-containing protein compare
BWI76_RS11255 -4.1 -2.7 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS21165 -3.9 -2.0 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS11250 -3.8 -2.0 spermidine/putrescine ABC transporter permease PotB compare
BWI76_RS00875 -3.7 -7.2 DNA-binding transcriptional regulator FabR compare
BWI76_RS08730 -3.7 -4.5 histidine utilization repressor compare
BWI76_RS06540 -3.4 -2.3 DNA-binding protein HU-beta compare
BWI76_RS00140 -3.4 -1.3 phosphate transport system regulator PhoU compare
BWI76_RS11240 -3.4 -5.2 spermidine/putrescine ABC transporter substrate-binding protein PotD compare
BWI76_RS16990 -3.4 -4.5 ABC transporter ATP-binding protein compare
BWI76_RS16490 -3.4 -2.5 glutaredoxin compare
BWI76_RS01125 -3.4 -4.6 4-alpha-L-fucosyltransferase compare
BWI76_RS16995 -3.3 -7.1 Fe-S cluster assembly protein SufB compare
BWI76_RS16975 -3.3 -5.4 cysteine desufuration protein SufE compare
BWI76_RS22805 -3.3 -8.5 GTP diphosphokinase compare
BWI76_RS11245 -3.2 -7.2 spermidine/putrescine ABC transporter permease PotC compare
BWI76_RS02530 -3.2 -2.8 tRNA dimethylallyltransferase compare
BWI76_RS21010 -3.1 -3.4 Negative regulator of nickel and cobalt uptake (YfgG) (from data) compare
BWI76_RS23240 -3.0 -2.9 exonuclease V subunit gamma compare
BWI76_RS25160 -3.0 -2.5 transcription elongation factor GreA compare
BWI76_RS05015 -3.0 -3.2 transcriptional regulator compare
BWI76_RS01095 -2.9 -3.0 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS26455 -2.9 -4.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS06675 -2.9 -9.1 nickel/cobalt efflux protein RcnA conserved
BWI76_RS09660 -2.7 -1.9 DNA translocase FtsK compare
BWI76_RS11275 -2.6 -6.9 sensor protein PhoQ compare
BWI76_RS01210 -2.6 -4.3 tyrosine recombinase XerC compare
BWI76_RS19935 -2.6 -1.9 hypothetical protein compare
BWI76_RS01800 -2.6 -5.1 glucose-6-phosphate isomerase compare
BWI76_RS08395 -2.5 -2.5 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS26460 -2.5 -5.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS01115 -2.5 -2.9 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS01110 -2.4 -6.9 TDP-fucosamine acetyltransferase compare
BWI76_RS03665 -2.4 -1.6 ABC transporter ATP-binding protein compare
BWI76_RS15825 -2.4 -2.2 hypothetical protein compare
BWI76_RS18935 -2.3 -7.3 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23330 -2.3 -4.8 transcriptional regulator GalR compare
BWI76_RS04305 -2.3 -1.5 molecular chaperone DnaJ compare
BWI76_RS25280 -2.3 -2.0 RNase adaptor protein RapZ compare
BWI76_RS26175 -2.2 -5.5 DeoR/GlpR family transcriptional regulator compare
BWI76_RS08535 -2.2 -3.1 translocation protein TolB compare
BWI76_RS06245 -2.2 -4.1 proline-specific permease ProY compare
BWI76_RS27450 -2.2 -3.9 ferredoxin--NADP(+) reductase compare
BWI76_RS26665 -2.2 -3.8 DNA-binding response regulator compare
BWI76_RS26245 -2.1 -3.6 transcriptional regulator compare
BWI76_RS09970 -2.1 -4.1 porin OmpA compare
BWI76_RS20640 -2.1 -6.2 cysteine synthase A compare
BWI76_RS09195 -2.1 -1.9 N-acetyltransferase compare
BWI76_RS26075 -2.0 -4.9 DNA adenine methylase compare
BWI76_RS19370 -2.0 -7.9 fructose-bisphosphate aldolase compare
BWI76_RS11010 -2.0 -3.0 30S ribosomal protein S5 alanine N-acetyltransferase compare
BWI76_RS26425 -2.0 -7.9 zinc/cadmium/mercury/lead-transporting ATPase compare
BWI76_RS19850 -2.0 -1.9 tRNA-Pro compare
BWI76_RS17720 -2.0 -1.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS23230 -1.9 -3.4 exodeoxyribonuclease V subunit beta compare
BWI76_RS06525 -1.9 -4.1 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS06930 -1.9 -6.7 iron export ABC transporter permease subunit FetB conserved
BWI76_RS15835 -1.9 -1.3 hypothetical protein compare
BWI76_RS16980 -1.9 -2.7 bifunctional cysteine desulfurase/selenocysteine lyase compare
BWI76_RS13095 -1.8 -2.3 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS08205 -1.8 -4.2 DNA-binding transcriptional dual regulator NagC compare
BWI76_RS06530 -1.8 -4.7 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS17000 -1.8 -3.3 Fe-S cluster assembly scaffold SufA compare
BWI76_RS17565 -1.8 -2.2 hypothetical protein compare
BWI76_RS20915 -1.8 -5.0 peroxiredoxin compare
BWI76_RS06185 -1.8 -8.1 shikimate kinase II compare
BWI76_RS01120 -1.7 -5.1 O-antigen translocase compare
BWI76_RS06925 -1.7 -9.5 iron ABC transporter ATP-binding protein FetA compare
BWI76_RS19035 -1.7 -6.5 dTDP-rhamnosyl transferase compare
BWI76_RS05880 -1.7 -1.9 AraC-type DNA-binding domain-containing protein compare
BWI76_RS24900 -1.7 -2.1 DeoR family transcriptional regulator compare
BWI76_RS19050 -1.7 -8.7 NAD(P)-dependent oxidoreductase compare
BWI76_RS18950 -1.7 -3.2 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS19040 -1.6 -6.7 hypothetical protein compare
BWI76_RS26610 -1.6 -9.1 oligopeptidase A conserved
BWI76_RS02505 -1.6 -7.9 tRNA epoxyqueuosine(34) reductase QueG compare
BWI76_RS26570 -1.6 -2.9 anion permease compare
BWI76_RS14915 -1.6 -2.8 hypothetical protein compare
BWI76_RS19055 -1.6 -7.0 dTDP-4-dehydrorhamnose 3,5-epimerase compare
BWI76_RS05205 -1.6 -4.8 type I methionyl aminopeptidase conserved
BWI76_RS20995 -1.6 -2.8 RNA degradosome polyphosphate kinase compare
BWI76_RS08530 -1.6 -1.8 protein TolA compare
BWI76_RS20910 -1.6 -3.2 glycine cleavage system transcriptional repressor compare
BWI76_RS18555 -1.5 -6.4 MATE family multidrug exporter compare
BWI76_RS11155 -1.5 -2.7 penicillin-binding protein activator LpoB compare
BWI76_RS27290 -1.5 -5.6 hypothetical protein compare
BWI76_RS05005 -1.5 -2.4 polynucleotide adenylyltransferase compare
BWI76_RS08215 -1.5 -3.8 glucosamine-6-phosphate deaminase compare
BWI76_RS26620 -1.5 -1.1 Fe-S biogenesis protein NfuA compare
BWI76_RS01135 -1.5 -4.8 lipopolysaccharide N-acetylmannosaminouronosyltransferase compare
BWI76_RS01900 -1.5 -4.1 tRNA-dihydrouridine synthase A compare
BWI76_RS11700 -1.5 -1.4 hypothetical protein compare
BWI76_RS00740 -1.4 -3.1 ribonuclease E activity regulator RraA compare
BWI76_RS14005 -1.4 -1.8 TetR family transcriptional regulator compare
BWI76_RS16205 -1.4 -5.1 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS18925 -1.4 -5.7 histidinol dehydrogenase compare
BWI76_RS09890 -1.4 -6.6 aminopeptidase N conserved
BWI76_RS05260 -1.4 -1.5 chaperone compare
BWI76_RS27305 -1.4 -6.2 glycosyl transferase compare
BWI76_RS04970 -1.4 -2.4 ABC transporter permease compare
BWI76_RS23265 -1.4 -3.3 hypothetical protein compare
BWI76_RS08525 -1.4 -2.5 colicin transporter compare
BWI76_RS01090 -1.4 -4.2 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
BWI76_RS27280 -1.4 -7.2 polymerase compare
BWI76_RS21395 -1.3 -2.0 DTW domain-containing protein compare
BWI76_RS08210 -1.3 -2.2 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS11940 -1.3 -4.6 aconitate hydratase 1 compare
BWI76_RS08385 -1.3 -2.6 citrate (Si)-synthase compare
BWI76_RS22055 -1.3 -6.8 ribonucleotide-diphosphate reductase compare
BWI76_RS11150 -1.3 -1.3 membrane protein compare
BWI76_RS01885 -1.3 -1.2 CsbD family protein compare
BWI76_RS08520 -1.3 -1.7 colicin transporter TolQ compare
BWI76_RS18605 -1.3 -1.5 oxidoreductase molybdopterin-binding protein compare
BWI76_RS27440 -1.3 -2.7 DNA helicase RecG compare
BWI76_RS24380 -1.3 -4.8 esterase YqiA compare
BWI76_RS00225 -1.3 -4.4 16S rRNA methyltransferase G conserved
BWI76_RS05120 -1.3 -6.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS22120 -1.3 -3.5 glutamate--cysteine ligase compare
BWI76_RS18940 -1.3 -2.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS25505 -1.3 -4.7 RNase E specificity factor CsrD compare
BWI76_RS19010 -1.3 -2.3 polysaccharide pyruvyl transferase yvff compare
BWI76_RS17190 -1.3 -1.7 TonB system transport protein TonB compare
BWI76_RS01890 -1.2 -2.9 transcriptional regulator Zur compare
BWI76_RS05425 -1.2 -4.3 EEP domain-containing protein compare
BWI76_RS18985 -1.2 -7.5 LPS O-antigen ABC transporter ATP-binding protein compare
BWI76_RS11430 -1.2 -1.1 lipoprotein compare
BWI76_RS16390 -1.2 -4.9 dipeptide/tripeptide permease A compare
BWI76_RS22060 -1.2 -5.9 ribonucleotide-diphosphate reductase subunit beta compare
BWI76_RS27275 -1.2 -4.8 hypothetical protein compare
BWI76_RS13125 -1.2 -2.7 3-hydroxyacyl-CoA dehydrogenase compare
BWI76_RS22095 -1.2 -2.7 multidrug export protein EmrA compare
BWI76_RS25065 -1.2 -3.1 polyribonucleotide nucleotidyltransferase compare
BWI76_RS18420 -1.2 -5.8 DNA (cytosine-5-)-methyltransferase compare
BWI76_RS11190 -1.2 -2.2 putative TetR/AcrR family transcriptional regulatory protein compare
BWI76_RS22085 -1.2 -1.9 L-valine transporter subunit YgaH compare
BWI76_RS13245 -1.2 -2.2 DNA-damage-inducible protein I compare
BWI76_RS24100 -1.2 -2.7 YggS family pyridoxal phosphate enzyme compare
BWI76_RS04955 -1.2 -1.2 hypoxanthine phosphoribosyltransferase compare
BWI76_RS08370 -1.2 -2.4 membrane protein compare
BWI76_RS08425 -1.2 -3.2 succinyl-CoA ligase subunit beta compare
BWI76_RS09530 -1.1 -1.0 hypothetical protein compare
BWI76_RS18930 -1.1 -3.2 histidinol-phosphate transaminase compare
BWI76_RS13755 -1.1 -1.5 hypothetical protein compare
BWI76_RS15840 -1.1 -3.4 prophage protein compare
BWI76_RS18990 -1.1 -7.8 ABC transporter permease compare
BWI76_RS20375 -1.1 -1.5 membrane protein compare
BWI76_RS00715 -1.1 -1.7 two-component sensor histidine kinase compare
BWI76_RS01190 -1.1 -1.5 iron donor protein CyaY compare
BWI76_RS12450 -1.1 -1.0 phage shock protein PspA compare
BWI76_RS24385 -1.1 -5.5 phosphodiesterase compare
BWI76_RS15645 -1.1 -5.1 gp6 compare
BWI76_RS12090 -1.1 -1.0 HNH endonuclease compare
BWI76_RS21130 -1.1 -1.3 Fe-S assembly protein IscX compare
BWI76_RS21450 -1.1 -2.1 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS27460 -1.0 -2.6 hypothetical protein compare
BWI76_RS09150 -1.0 -2.0 DNA-binding transcriptional repressor DeoR compare
BWI76_RS00440 -1.0 -1.2 CopG family transcriptional regulator compare
BWI76_RS19770 -1.0 -1.6 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS06240 -1.0 -2.4 branched-chain amino acid transport system 2 carrier protein BrnQ compare
BWI76_RS09760 -1.0 -4.0 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS15990 -1.0 -3.2 serine protease compare
BWI76_RS06325 -1.0 -2.4 hypothetical protein compare
BWI76_RS25960 -1.0 -3.2 NUDIX hydrolase compare
BWI76_RS19495 -1.0 -0.9 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS26005 -1.0 -2.8 glutamine amidotransferase compare
BWI76_RS06665 -1.0 -2.1 membrane protein compare
BWI76_RS21115 -1.0 -1.5 3-mercaptopyruvate sulfurtransferase compare
BWI76_RS05175 -1.0 -8.3 dGTPase compare
BWI76_RS26890 -1.0 -0.9 hypothetical protein compare
BWI76_RS24620 -1.0 -3.5 PadR family transcriptional regulator compare
BWI76_RS20320 -1.0 -3.4 histidine/lysine/arginine/ornithine ABC transporter ATP-binding protein HisP compare
BWI76_RS10710 -1.0 -3.6 Glutamate--putrescine ligase (EC 6.3.1.11) (from data) compare
BWI76_RS11765 -1.0 -2.7 bifunctional transporter/kinase compare
BWI76_RS26670 -1.0 -5.0 two-component sensor histidine kinase compare
BWI76_RS00240 -1.0 -1.5 FMN-binding protein MioC compare
BWI76_RS15850 -1.0 -1.0 DUF1317 domain-containing protein compare
BWI76_RS18000 -1.0 -1.6 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
BWI76_RS22975 -1.0 -1.7 tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA compare
BWI76_RS20430 -0.9 -1.9 penicillin-insensitive murein endopeptidase compare
BWI76_RS06590 -0.9 -4.5 multidrug ABC transporter permease/ATP-binding protein compare
BWI76_RS20330 -0.9 -2.4 histidine/lysine/arginine/ornithine ABC transporter permease HisQ compare
BWI76_RS09755 -0.9 -2.9 phosphoserine transaminase compare
BWI76_RS14390 -0.9 -1.4 hypothetical protein compare
BWI76_RS11015 -0.9 -1.7 hypothetical protein compare
BWI76_RS26730 -0.9 -1.9 inner membrane protein YhjD compare
BWI76_RS22950 -0.9 -2.0 membrane protein compare
BWI76_RS19905 -0.9 -2.6 OmpK36 porin compare
BWI76_RS06800 -0.9 -0.9 DUF2496 domain-containing protein compare
BWI76_RS00940 -0.9 -4.6 transcriptional regulator HdfR compare
BWI76_RS19690 -0.9 -2.0 LysR family transcriptional regulator compare
BWI76_RS09455 -0.9 -1.7 YbjN domain-containing protein compare
BWI76_RS18165 -0.9 -1.3 NUDIX pyrophosphatase compare
BWI76_RS08405 -0.9 -1.3 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS16965 -0.9 -2.4 murein lipoprotein compare
BWI76_RS21535 -0.9 -4.5 inner membrane protein YpjD compare
BWI76_RS20920 -0.9 -3.9 AI-2E family transporter compare
BWI76_RS22050 -0.9 -3.0 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
BWI76_RS06295 -0.9 -2.4 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare


Specific Phenotypes

For 24 genes in this experiment

For stress Nickel (II) chloride hexahydrate in Klebsiella michiganensis M5al

For stress Nickel (II) chloride hexahydrate across organisms