Experiment set6IT089 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Alanine

200 most important genes:

  gene name fitness t score description  
MMP_RS06355 -5.3 -3.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07345 -4.8 -9.5 glycine synthesis protein GlyXL (from data) compare
MMP_RS03450 -4.7 -2.3 glycine synthesis protein GlyXS (from data) compare
MMP_RS08435 -4.6 -3.0 Era-like GTP-binding protein compare
MMP_RS06475 -4.4 -6.9 FAD-dependent oxidoreductase compare
MMP_RS05500 -4.3 -10.3 2-isopropylmalate synthase compare
MMP_RS01175 -4.2 -4.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS08300 -4.1 -1.8 metal-sulfur cluster assembly factor compare
MMP_RS02900 -4.1 -0.7 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS03035 -4.0 -4.7 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02145 -3.8 -12.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS05510 -3.8 -10.0 Rrf2 family transcriptional regulator compare
MMP_RS07845 -3.7 -3.3 LL-diaminopimelate aminotransferase compare
MMP_RS07635 -3.7 -8.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS06400 -3.7 -2.5 4Fe-4S binding protein compare
MMP_RS08165 -3.7 -3.2 phosphoglycerate dehydrogenase compare
MMP_RS07775 -3.7 -7.1 alanine dehydrogenase compare
MMP_RS07365 -3.7 -14.0 2-phosphoglycerate kinase compare
MMP_RS05515 -3.6 -10.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS03640 -3.6 -4.4 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS06350 -3.6 -10.0 HesA/MoeB/ThiF family protein compare
MMP_RS08720 -3.6 -2.3 4Fe-4S binding protein compare
MMP_RS03015 -3.6 -12.6 GTP 3' 8-cyclase MoaA compare
MMP_RS01545 -3.5 -1.4 CBS domain-containing protein compare
MMP_RS07525 -3.5 -9.0 4Fe-4S binding protein compare
MMP_RS04215 -3.5 -9.3 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS01800 -3.4 -5.6 TIGR00303 family protein compare
MMP_RS01385 -3.4 -0.8 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06895 -3.4 -2.0 selenocysteine-specific translation elongation factor compare
MMP_RS00300 -3.4 -1.0 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05845 -3.3 -2.7 tRNA-intron lyase compare
MMP_RS01610 -3.2 -4.5 hypothetical protein compare
MMP_RS04605 -3.2 -7.1 cobalt ECF transporter T component CbiQ compare
MMP_RS06285 -3.2 -3.7 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS03435 -3.2 -2.3 ketol-acid reductoisomerase compare
MMP_RS01455 -3.2 -8.8 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS08790 -3.1 -2.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS02010 -3.1 -15.8 PHP domain-containing protein compare
MMP_RS06270 -3.1 -6.6 TIGR00300 family protein compare
MMP_RS03700 -3.0 -10.8 sodium:proton antiporter compare
MMP_RS01500 -3.0 -3.2 CBS domain-containing protein compare
MMP_RS02240 -3.0 -5.5 methanogenesis marker 7 protein compare
MMP_RS04900 -3.0 -20.6 hypothetical protein compare
MMP_RS06375 -3.0 -4.6 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS02135 -3.0 -8.0 DUF5612 domain-containing protein compare
MMP_RS08650 -2.9 -3.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS04710 -2.9 -2.1 hypothetical protein compare
MMP_RS06625 -2.9 -2.6 DNA primase compare
MMP_RS08745 -2.9 -8.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06730 -2.8 -2.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS06295 -2.8 -9.6 methanogenesis marker 14 protein compare
MMP_RS07630 -2.8 -1.4 ATP-binding cassette domain-containing protein compare
MMP_RS03600 -2.8 -2.9 triose-phosphate isomerase compare
MMP_RS00455 -2.7 -7.9 orotate phosphoribosyltransferase-like protein compare
MMP_RS01755 -2.7 -1.7 DUF2097 domain-containing protein compare
MMP_RS08715 -2.7 -1.8 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01225 -2.7 -7.8 DUF5379 domain-containing protein compare
MMP_RS04890 -2.7 -1.1 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS00915 -2.7 -8.7 DUF116 domain-containing protein compare
MMP_RS01325 -2.7 -2.8 dihydroneopterin aldolase family protein compare
MMP_RS02245 -2.7 -4.4 hypothetical protein compare
MMP_RS08210 -2.6 -2.6 phosphatidylglycerophosphatase A compare
MMP_RS01375 -2.6 -16.5 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS01265 -2.6 -4.3 hypothetical protein compare
MMP_RS04615 -2.6 -4.7 PDGLE domain-containing protein compare
MMP_RS00040 -2.5 -4.8 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS07445 -2.5 -5.7 helix-turn-helix domain-containing protein compare
MMP_RS04780 -2.5 -3.2 ribonuclease P compare
MMP_RS02355 -2.5 -3.8 30S ribosomal protein S27ae compare
MMP_RS07380 -2.5 -2.4 transcription elongation factor Spt5 compare
MMP_RS03025 -2.5 -6.6 molybdenum cofactor guanylyltransferase compare
MMP_RS04790 -2.5 -13.9 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS06940 -2.5 -4.3 polyprenyl diphosphate synthase compare
MMP_RS04500 -2.5 -18.8 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS07075 -2.5 -5.9 phosphomannomutase/phosphoglucomutase compare
MMP_RS07600 -2.4 -2.7 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS04620 -2.4 -13.3 cobalt transporter CbiM compare
MMP_RS04720 -2.4 -4.0 DedA family protein compare
MMP_RS07435 -2.4 -2.2 GMP synthase subunit A compare
MMP_RS07765 -2.4 -13.3 sodium:alanine symporter family protein compare
MMP_RS08635 -2.4 -2.1 UbiA family prenyltransferase compare
MMP_RS01005 -2.4 -1.6 riboflavin synthase compare
MMP_RS03445 -2.3 -1.2 methanogenesis marker 17 protein compare
MMP_RS05925 -2.3 -3.9 small nuclear ribonucleoprotein compare
MMP_RS03960 -2.3 -1.3 hypothetical protein compare
MMP_RS03475 -2.3 -0.8 hypothetical protein compare
MMP_RS03315 -2.3 -1.4 ferrous iron transport protein A compare
MMP_RS06120 -2.3 -2.5 UPF0147 family protein compare
MMP_RS05930 -2.3 -2.7 3-isopropylmalate dehydratase large subunit compare
MMP_RS00310 -2.3 -7.7 CBS domain-containing protein compare
MMP_RS04585 -2.3 -8.6 AIR synthase related protein compare
MMP_RS03250 -2.3 -3.4 MJ1244 family protein compare
MMP_RS02195 -2.2 -4.6 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07955 -2.2 -5.7 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS06370 -2.2 -5.6 biotin synthase BioB compare
MMP_RS08500 -2.2 -6.2 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS08460 -2.2 -3.1 proteasome-activating nucleotidase compare
MMP_RS00375 -2.1 -5.7 ammonium transporter compare
MMP_RS01380 -2.1 -4.6 PHP domain-containing protein compare
MMP_RS08095 -2.1 -6.6 dethiobiotin synthase compare
MMP_RS09020 -2.1 -1.7 hypothetical protein compare
MMP_RS05920 -2.1 -0.7 50S ribosomal protein L37e compare
MMP_RS00985 -2.1 -5.6 CDC48 family AAA ATPase compare
MMP_RS00515 -2.0 -1.0 DUF655 domain-containing protein compare
MMP_RS07390 -2.0 -2.1 cell division protein FtsZ compare
MMP_RS05430 -2.0 -4.1 TIGR00288 family NYN domain-containing protein compare
MMP_RS00685 -2.0 -4.3 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01220 -2.0 -7.2 hypothetical protein compare
MMP_RS01900 -2.0 -10.8 hypothetical protein compare
MMP_RS01905 -1.9 -11.8 glycosyltransferase compare
MMP_RS00750 -1.9 -2.4 fumarate hydratase compare
MMP_RS05815 -1.9 -2.4 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS01960 -1.9 -1.0 hypothetical protein compare
MMP_RS00305 -1.9 -2.1 phosphoribosyl-ATP diphosphatase compare
MMP_RS05250 -1.9 -1.6 NFYB/HAP3 family transcription factor subunit compare
MMP_RS06315 -1.9 -0.8 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS01795 -1.9 -1.6 methanogenesis marker 6 protein compare
MMP_RS04685 -1.8 -2.9 DUF126 domain-containing protein compare
MMP_RS04955 -1.8 -5.8 DNA topoisomerase I compare
MMP_RS06230 -1.8 -2.7 helix-turn-helix domain-containing protein compare
MMP_RS01020 -1.8 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS01955 -1.8 -2.5 hypothetical protein compare
MMP_RS02280 -1.8 -1.0 DUF211 domain-containing protein compare
MMP_RS07535 -1.8 -8.0 4Fe-4S binding protein compare
MMP_RS08760 -1.7 -1.8 hypothetical protein compare
MMP_RS00110 -1.7 -2.2 hypothetical protein compare
MMP_RS04775 -1.7 -3.3 adenosylhomocysteinase compare
MMP_RS08440 -1.7 -2.7 cell division protein SepF compare
MMP_RS01365 -1.7 -3.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS03485 -1.7 -3.5 TIGR00267 family protein compare
MMP_RS07355 -1.7 -1.1 transcription factor S compare
MMP_RS00555 -1.7 -5.6 MFS transporter compare
MMP_RS00695 -1.7 -0.9 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08100 -1.7 -6.8 8-amino-7-oxononanoate synthase compare
MMP_RS01600 -1.6 -2.2 50S ribosomal protein L15e compare
MMP_RS07580 -1.6 -2.3 DUF356 domain-containing protein compare
MMP_RS06670 -1.6 -5.1 glucose-6-phosphate isomerase compare
MMP_RS07200 -1.6 -5.6 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06175 -1.6 -5.4 winged helix-turn-helix transcriptional regulator compare
MMP_RS05765 -1.6 -4.0 M42 family metallopeptidase compare
MMP_RS03400 -1.6 -2.7 archease compare
MMP_RS05265 -1.6 -1.7 2-isopropylmalate synthase compare
MMP_RS01925 -1.6 -7.6 DUF1616 domain-containing protein compare
MMP_RS01880 -1.6 -5.9 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS03390 -1.6 -7.3 malate dehydrogenase compare
MMP_RS06885 -1.5 -2.2 50S ribosome-binding GTPase compare
MMP_RS04465 -1.5 -9.6 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS05540 -1.5 -1.8 hypothetical protein compare
MMP_RS03580 -1.5 -2.9 signal recognition particle-docking protein FtsY compare
MMP_RS02345 -1.5 -3.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS06925 -1.5 -2.3 ribonuclease VapC4 compare
MMP_RS06725 -1.5 -8.6 hypothetical protein compare
MMP_RS07420 -1.5 -4.6 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS01700 -1.5 -1.0 dihydroxy-acid dehydratase compare
MMP_RS07750 -1.5 -3.6 DUF357 domain-containing protein compare
MMP_RS08105 -1.5 -5.5 6-carboxyhexanoate--CoA ligase compare
MMP_RS05345 -1.5 -5.7 hypothetical protein compare
MMP_RS07545 -1.5 -1.2 HTH domain-containing protein compare
MMP_RS07605 -1.5 -2.7 diadenylate cyclase compare
MMP_RS08820 -1.5 -4.4 hypothetical protein compare
MMP_RS00895 -1.5 -4.1 hypothetical protein compare
MMP_RS06630 -1.5 -0.9 UPF0058 family protein compare
MMP_RS00520 -1.5 -1.5 RNA polymerase Rpb4 family protein compare
MMP_RS04470 -1.5 -8.7 nitrogenase compare
MMP_RS01830 -1.5 -1.8 tRNA-Val compare
MMP_RS08785 -1.4 -1.0 RNA-protein complex protein Nop10 compare
MMP_RS01840 -1.4 -5.6 TIGR00289 family protein compare
MMP_RS02480 -1.4 -2.5 hypothetical protein compare
MMP_RS06020 -1.4 -4.0 archaeoflavoprotein AfpA compare
MMP_RS01665 -1.4 -2.3 DUF2111 domain-containing protein compare
MMP_RS01725 -1.4 -4.2 class I SAM-dependent methyltransferase family protein compare
MMP_RS04460 -1.4 -9.0 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS06855 -1.4 -6.0 hypothetical protein compare
MMP_RS01440 -1.4 -4.1 NAAT family transporter compare
MMP_RS03340 -1.4 -0.9 ABC transporter ATP-binding protein compare
MMP_RS03095 -1.4 -4.7 diphthine synthase compare
MMP_RS00810 -1.4 -5.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07005 -1.3 -0.6 4Fe-4S binding protein compare
MMP_RS07755 -1.3 -0.9 DUF555 domain-containing protein compare
MMP_RS02340 -1.3 -1.4 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05485 -1.3 -5.7 cysteine--tRNA ligase compare
MMP_RS05640 -1.3 -5.4 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS04485 -1.3 -7.5 putative beta-lysine N-acetyltransferase compare
MMP_RS01910 -1.3 -7.3 UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing) compare
MMP_RS02800 -1.3 -5.1 nucleotidyltransferase domain-containing protein compare
MMP_RS01575 -1.3 -2.8 aldolase compare
MMP_RS03440 -1.2 -1.1 MoaD/ThiS family protein compare
MMP_RS01885 -1.2 -5.2 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS05245 -1.2 -5.4 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08660 -1.2 -5.7 DHH family phosphoesterase compare
MMP_RS04785 -1.2 -7.6 hypothetical protein compare
MMP_RS05295 -1.2 -7.4 minichromosome maintenance protein MCM compare
MMP_RS05460 -1.2 -6.1 YcaO-related McrA-glycine thioamidation protein compare
MMP_RS06980 -1.2 -4.8 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS07645 -1.2 -4.8 aldehyde dehydrogenase family protein compare
MMP_RS05285 -1.2 -5.4 MMPL family transporter compare
MMP_RS05315 -1.1 -1.5 hypothetical protein compare
MMP_RS03110 -1.1 -3.6 glycosyltransferase family 2 protein compare
MMP_RS08195 -1.1 -5.5 hypothetical protein compare
MMP_RS07090 -1.1 -4.2 tRNA (adenine-N1)-methyltransferase compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source L-Alanine in Methanococcus maripaludis S2

For nitrogen source L-Alanine across organisms