Experiment set6IT088 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Alanine

200 most important genes:

  gene name fitness t score description  
MMP_RS03450 -6.4 -2.3 glycine synthesis protein GlyXS (from data) compare
MMP_RS01795 -5.2 -2.0 methanogenesis marker 6 protein compare
MMP_RS08165 -4.8 -2.9 phosphoglycerate dehydrogenase compare
MMP_RS07635 -4.6 -10.5 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS08790 -4.6 -2.4 translation initiation factor IF-2 subunit alpha compare
MMP_RS05500 -4.5 -12.1 2-isopropylmalate synthase compare
MMP_RS07345 -4.5 -6.9 glycine synthesis protein GlyXL (from data) compare
MMP_RS01175 -4.5 -5.1 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS01385 -4.4 -0.7 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS01545 -4.2 -1.1 CBS domain-containing protein compare
MMP_RS05920 -4.2 -0.7 50S ribosomal protein L37e compare
MMP_RS06475 -4.1 -6.4 FAD-dependent oxidoreductase compare
MMP_RS07525 -4.0 -9.7 4Fe-4S binding protein compare
MMP_RS01610 -4.0 -3.4 hypothetical protein compare
MMP_RS01005 -4.0 -1.2 riboflavin synthase compare
MMP_RS00300 -3.9 -0.9 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS07365 -3.9 -14.8 2-phosphoglycerate kinase compare
MMP_RS08720 -3.8 -2.2 4Fe-4S binding protein compare
MMP_RS04710 -3.8 -2.0 hypothetical protein compare
MMP_RS00515 -3.8 -0.8 DUF655 domain-containing protein compare
MMP_RS00455 -3.7 -12.6 orotate phosphoribosyltransferase-like protein compare
MMP_RS03600 -3.7 -2.7 triose-phosphate isomerase compare
MMP_RS06350 -3.6 -9.3 HesA/MoeB/ThiF family protein compare
MMP_RS00040 -3.6 -8.3 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS05510 -3.6 -8.6 Rrf2 family transcriptional regulator compare
MMP_RS01455 -3.6 -5.7 nickel pincer cofactor biosynthesis protein LarC compare
MMP_RS07380 -3.6 -2.2 transcription elongation factor Spt5 compare
MMP_RS01020 -3.6 -1.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06270 -3.6 -8.1 TIGR00300 family protein compare
MMP_RS08435 -3.5 -2.4 Era-like GTP-binding protein compare
MMP_RS06355 -3.5 -2.6 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS07775 -3.5 -7.3 alanine dehydrogenase compare
MMP_RS06120 -3.5 -2.3 UPF0147 family protein compare
MMP_RS03445 -3.5 -1.1 methanogenesis marker 17 protein compare
MMP_RS04605 -3.4 -6.4 cobalt ECF transporter T component CbiQ compare
MMP_RS02010 -3.4 -12.1 PHP domain-containing protein compare
MMP_RS03960 -3.4 -1.2 hypothetical protein compare
MMP_RS01755 -3.4 -1.5 DUF2097 domain-containing protein compare
MMP_RS08500 -3.4 -6.6 pyridoxal 5'-phosphate synthase glutaminase subunit PdxT compare
MMP_RS04615 -3.3 -4.1 PDGLE domain-containing protein compare
MMP_RS01325 -3.3 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS08635 -3.3 -2.1 UbiA family prenyltransferase compare
MMP_RS01800 -3.3 -4.8 TIGR00303 family protein compare
MMP_RS05930 -3.2 -2.6 3-isopropylmalate dehydratase large subunit compare
MMP_RS03315 -3.2 -1.2 ferrous iron transport protein A compare
MMP_RS03640 -3.2 -3.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS02145 -3.2 -9.5 winged helix-turn-helix transcriptional regulator compare
MMP_RS08300 -3.2 -1.6 metal-sulfur cluster assembly factor compare
MMP_RS02135 -3.1 -6.5 DUF5612 domain-containing protein compare
MMP_RS04685 -3.1 -3.5 DUF126 domain-containing protein compare
MMP_RS05515 -3.1 -9.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS04890 -3.1 -1.0 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS07845 -3.1 -2.4 LL-diaminopimelate aminotransferase compare
MMP_RS03035 -3.1 -4.6 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07435 -3.0 -2.1 GMP synthase subunit A compare
MMP_RS06285 -3.0 -3.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00305 -3.0 -2.2 phosphoribosyl-ATP diphosphatase compare
MMP_RS06730 -3.0 -1.8 phosphopantothenate/pantothenate synthetase compare
MMP_RS04900 -3.0 -18.9 hypothetical protein compare
MMP_RS08745 -3.0 -7.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03015 -2.9 -9.6 GTP 3' 8-cyclase MoaA compare
MMP_RS06375 -2.9 -4.2 ATP-dependent sacrificial sulfur transferase LarE compare
MMP_RS05265 -2.9 -2.5 2-isopropylmalate synthase compare
MMP_RS00915 -2.9 -7.5 DUF116 domain-containing protein compare
MMP_RS03700 -2.9 -10.0 sodium:proton antiporter compare
MMP_RS04585 -2.9 -11.7 AIR synthase related protein compare
MMP_RS06885 -2.8 -2.7 50S ribosome-binding GTPase compare
MMP_RS01375 -2.8 -16.8 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS03580 -2.8 -4.1 signal recognition particle-docking protein FtsY compare
MMP_RS01225 -2.8 -5.4 DUF5379 domain-containing protein compare
MMP_RS04500 -2.8 -18.6 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS04215 -2.7 -4.4 nickel pincer cofactor biosynthesis protein LarB compare
MMP_RS06670 -2.7 -7.2 glucose-6-phosphate isomerase compare
MMP_RS07390 -2.7 -3.1 cell division protein FtsZ compare
MMP_RS08210 -2.7 -2.5 phosphatidylglycerophosphatase A compare
MMP_RS06295 -2.7 -8.6 methanogenesis marker 14 protein compare
MMP_RS05250 -2.6 -1.5 NFYB/HAP3 family transcription factor subunit compare
MMP_RS00750 -2.6 -2.7 fumarate hydratase compare
MMP_RS07445 -2.6 -5.9 helix-turn-helix domain-containing protein compare
MMP_RS01220 -2.6 -9.9 hypothetical protein compare
MMP_RS07005 -2.6 -0.7 4Fe-4S binding protein compare
MMP_RS04790 -2.6 -11.1 4-hydroxy-tetrahydrodipicolinate reductase compare
MMP_RS07765 -2.5 -12.2 sodium:alanine symporter family protein compare
MMP_RS06020 -2.5 -5.5 archaeoflavoprotein AfpA compare
MMP_RS04620 -2.5 -11.9 cobalt transporter CbiM compare
MMP_RS06625 -2.5 -2.1 DNA primase compare
MMP_RS02280 -2.5 -1.0 DUF211 domain-containing protein compare
MMP_RS07955 -2.5 -6.1 FumA C-terminus/TtdB family hydratase beta subunit compare
MMP_RS08760 -2.5 -3.3 hypothetical protein compare
MMP_RS06400 -2.5 -1.8 4Fe-4S binding protein compare
MMP_RS08650 -2.5 -3.7 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS01265 -2.5 -2.2 hypothetical protein compare
MMP_RS01365 -2.4 -3.4 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS07545 -2.4 -1.1 HTH domain-containing protein compare
MMP_RS02195 -2.4 -4.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07075 -2.4 -4.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS03025 -2.4 -4.9 molybdenum cofactor guanylyltransferase compare
MMP_RS05925 -2.4 -3.3 small nuclear ribonucleoprotein compare
MMP_RS01500 -2.4 -2.5 CBS domain-containing protein compare
MMP_RS01380 -2.4 -4.8 PHP domain-containing protein compare
MMP_RS07755 -2.4 -1.3 DUF555 domain-containing protein compare
MMP_RS03205 -2.4 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS00110 -2.4 -2.7 hypothetical protein compare
MMP_RS03435 -2.4 -1.7 ketol-acid reductoisomerase compare
MMP_RS07355 -2.3 -1.1 transcription factor S compare
MMP_RS02900 -2.3 -0.6 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07600 -2.3 -3.2 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS00310 -2.3 -7.4 CBS domain-containing protein compare
MMP_RS04775 -2.3 -4.0 adenosylhomocysteinase compare
MMP_RS06630 -2.3 -1.1 UPF0058 family protein compare
MMP_RS09020 -2.2 -1.5 hypothetical protein compare
MMP_RS03475 -2.2 -0.7 hypothetical protein compare
MMP_RS07750 -2.2 -4.0 DUF357 domain-containing protein compare
MMP_RS08095 -2.2 -7.4 dethiobiotin synthase compare
MMP_RS01700 -2.2 -0.8 dihydroxy-acid dehydratase compare
MMP_RS06925 -2.1 -2.4 ribonuclease VapC4 compare
MMP_RS06855 -2.1 -8.6 hypothetical protein compare
MMP_RS05430 -2.1 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS06370 -2.1 -5.5 biotin synthase BioB compare
MMP_RS02245 -2.1 -3.0 hypothetical protein compare
MMP_RS01725 -2.1 -4.7 class I SAM-dependent methyltransferase family protein compare
MMP_RS07580 -2.1 -2.3 DUF356 domain-containing protein compare
MMP_RS05280 -2.1 -8.5 COG1361 S-layer family protein compare
MMP_RS03390 -2.0 -7.7 malate dehydrogenase compare
MMP_RS08100 -2.0 -6.6 8-amino-7-oxononanoate synthase compare
MMP_RS05540 -2.0 -2.9 hypothetical protein compare
MMP_RS02240 -2.0 -2.4 methanogenesis marker 7 protein compare
MMP_RS07630 -2.0 -1.7 ATP-binding cassette domain-containing protein compare
MMP_RS04955 -2.0 -6.8 DNA topoisomerase I compare
MMP_RS03440 -1.9 -1.2 MoaD/ThiS family protein compare
MMP_RS08105 -1.9 -7.1 6-carboxyhexanoate--CoA ligase compare
MMP_RS03250 -1.9 -2.9 MJ1244 family protein compare
MMP_RS05285 -1.9 -5.5 MMPL family transporter compare
MMP_RS07420 -1.9 -5.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04460 -1.9 -10.1 nitrogenase molybdenum-iron protein subunit beta compare
MMP_RS04780 -1.9 -2.6 ribonuclease P compare
MMP_RS00375 -1.9 -5.4 ammonium transporter compare
MMP_RS02355 -1.9 -2.5 30S ribosomal protein S27ae compare
MMP_RS00695 -1.9 -1.0 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS08595 -1.9 -1.0 flagellar protein C compare
MMP_RS04470 -1.9 -9.6 nitrogenase compare
MMP_RS01830 -1.8 -1.8 tRNA-Val compare
MMP_RS06725 -1.8 -8.2 hypothetical protein compare
MMP_RS02340 -1.8 -2.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS00985 -1.8 -4.4 CDC48 family AAA ATPase compare
MMP_RS06980 -1.8 -5.4 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS06895 -1.8 -1.3 selenocysteine-specific translation elongation factor compare
MMP_RS01955 -1.8 -3.0 hypothetical protein compare
MMP_RS01975 -1.8 -11.2 hypothetical protein compare
MMP_RS07535 -1.8 -7.9 4Fe-4S binding protein compare
MMP_RS07605 -1.8 -2.5 diadenylate cyclase compare
MMP_RS01900 -1.7 -10.0 hypothetical protein compare
MMP_RS07200 -1.7 -5.9 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS06230 -1.7 -2.1 helix-turn-helix domain-containing protein compare
MMP_RS08715 -1.7 -1.4 formylmethanofuran dehydrogenase subunit B compare
MMP_RS08460 -1.7 -2.2 proteasome-activating nucleotidase compare
MMP_RS08440 -1.7 -2.1 cell division protein SepF compare
MMP_RS00895 -1.7 -4.2 hypothetical protein compare
MMP_RS03400 -1.7 -2.2 archease compare
MMP_RS00810 -1.6 -7.2 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS00320 -1.6 -1.7 class I SAM-dependent methyltransferase compare
MMP_RS04465 -1.6 -9.4 nitrogenase iron-molybdenum cofactor biosynthesis protein NifE compare
MMP_RS01905 -1.6 -10.1 glycosyltransferase compare
MMP_RS05640 -1.6 -5.4 UTP--glucose-1-phosphate uridylyltransferase GalU compare
MMP_RS00555 -1.6 -3.8 MFS transporter compare
MMP_RS01720 -1.6 -1.8 replication factor C large subunit compare
MMP_RS03095 -1.6 -4.5 diphthine synthase compare
MMP_RS00685 -1.6 -3.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS05815 -1.6 -1.8 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS05535 -1.6 -4.3 hypothetical protein compare
MMP_RS04485 -1.5 -8.6 putative beta-lysine N-acetyltransferase compare
MMP_RS05845 -1.5 -1.8 tRNA-intron lyase compare
MMP_RS06315 -1.5 -0.9 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08590 -1.5 -3.0 flagellin compare
MMP_RS08605 -1.5 -4.5 flagellar protein E compare
MMP_RS06865 -1.5 -2.0 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS01140 -1.5 -2.7 molybdate ABC transporter permease subunit compare
MMP_RS06770 -1.5 -6.6 DHH family phosphoesterase compare
MMP_RS08660 -1.4 -5.5 DHH family phosphoesterase compare
MMP_RS01885 -1.4 -5.4 Gfo/Idh/MocA family oxidoreductase compare
MMP_RS08820 -1.4 -4.3 hypothetical protein compare
MMP_RS05295 -1.4 -6.8 minichromosome maintenance protein MCM compare
MMP_RS08195 -1.4 -5.0 hypothetical protein compare
MMP_RS06940 -1.4 -3.0 polyprenyl diphosphate synthase compare
MMP_RS07645 -1.4 -5.3 aldehyde dehydrogenase family protein compare
MMP_RS00315 -1.4 -4.6 Nif3-like dinuclear metal center hexameric protein compare
MMP_RS01100 -1.4 -1.3 ABC transporter ATP-binding protein compare
MMP_RS08840 -1.4 -8.2 class I SAM-dependent methyltransferase compare
MMP_RS06340 -1.4 -6.1 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS07575 -1.4 -2.5 RNA ligase partner protein compare
MMP_RS01840 -1.4 -6.3 TIGR00289 family protein compare
MMP_RS04720 -1.4 -2.2 DedA family protein compare
MMP_RS05345 -1.4 -5.1 hypothetical protein compare
MMP_RS06175 -1.4 -3.0 winged helix-turn-helix transcriptional regulator compare
MMP_RS08600 -1.4 -2.0 flagellar protein D compare
MMP_RS04690 -1.3 -3.5 class III signal peptide-containing protein compare
MMP_RS04450 -1.3 -5.1 P-II family nitrogen regulator compare
MMP_RS00830 -1.3 -1.6 purine phosphoribosyltransferase family protein compare
MMP_RS01880 -1.3 -4.0 DegT/DnrJ/EryC1/StrS family aminotransferase compare
MMP_RS01875 -1.3 -5.8 N-acetyltransferase compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source L-Alanine in Methanococcus maripaludis S2

For nitrogen source L-Alanine across organisms