Experiment set6IT088 for Methanococcus maripaludis S2

Compare to:

H2 N-free with 10mM L-Alanine

200 most detrimental genes:

  gene name fitness t score description  
MMP_RS05425 +3.5 11.3 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS07555 +3.0 2.5 monovalent cation/H+ antiporter subunit E compare
MMP_RS05555 +2.7 4.5 DUF4040 domain-containing protein compare
MMP_RS08350 +2.7 2.3 hypothetical protein compare
MMP_RS05550 +2.5 2.0 cation:proton antiporter compare
MMP_RS08330 +2.3 7.7 NADH-quinone oxidoreductase subunit H compare
MMP_RS08310 +2.0 4.3 TMEM165/GDT1 family protein compare
MMP_RS08370 +1.9 1.2 cation:proton antiporter subunit C compare
MMP_RS06575 +1.8 4.9 fluoride efflux transporter CrcB compare
MMP_RS00185 +1.8 13.2 potassium channel protein compare
MMP_RS02290 +1.6 7.4 MBL fold metallo-hydrolase compare
MMP_RS03550 +1.6 2.3 DUF2124 domain-containing protein compare
MMP_RS06860 +1.6 3.1 4Fe-4S binding protein compare
MMP_RS05695 +1.4 7.6 phospholipase D-like domain-containing protein compare
MMP_RS05975 +1.4 2.1 hypothetical protein compare
MMP_RS08365 +1.3 4.7 energy conserving hydrogenase EhbF compare
MMP_RS08335 +1.3 4.1 NADH-quinone oxidoreductase subunit B family protein compare
MMP_RS02045 +1.3 2.2 tRNA-Met compare
MMP_RS07730 +1.3 1.8 pyruvate synthase subunit beta compare
MMP_RS06325 +1.2 1.7 hypothetical protein compare
MMP_RS02805 +1.2 1.4 HEPN domain-containing protein compare
MMP_RS05950 +1.2 4.3 nickel-dependent hydrogenase large subunit compare
MMP_RS06930 +1.2 5.4 MBL fold metallo-hydrolase compare
MMP_RS00855 +1.2 3.9 DUF367 family protein compare
MMP_RS02675 +1.1 1.4 hypothetical protein compare
MMP_RS08070 +1.1 4.1 DUF2096 domain-containing protein compare
MMP_RS05795 +1.1 2.5 redox-regulated ATPase YchF compare
MMP_RS07840 +1.1 1.8 ribonuclease III compare
MMP_RS02110 +1.0 2.1 hypothetical protein compare
MMP_RS03065 +1.0 2.3 AzlC family ABC transporter permease compare
MMP_RS07615 +1.0 3.9 energy-coupling factor ABC transporter permease compare
MMP_RS00430 +1.0 1.7 hypothetical protein compare
MMP_RS08075 +0.9 2.7 DUF749 domain-containing protein compare
MMP_RS00295 +0.9 1.6 gamma carbonic anhydrase family protein compare
MMP_RS08355 +0.9 4.0 Na(+)/H(+) antiporter subunit B compare
MMP_RS03465 +0.9 1.1 adenine phosphoribosyltransferase compare
MMP_RS07890 +0.9 1.4 OB-fold nucleic acid binding domain-containing protein compare
MMP_RS06515 +0.9 1.2 UPF0489 family protein compare
MMP_RS01525 +0.9 1.4 nucleoside-diphosphate kinase compare
MMP_RS06335 +0.9 1.9 HAD family hydrolase compare
MMP_RS03080 +0.8 2.2 universal stress protein compare
MMP_RS05985 +0.8 2.7 hypothetical protein compare
MMP_RS03890 +0.8 1.7 DUF2540 domain-containing protein compare
MMP_RS02390 +0.8 2.6 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS08980 +0.8 2.1 hypothetical protein compare
MMP_RS07915 +0.8 3.3 DUF4870 domain-containing protein compare
MMP_RS06540 +0.8 1.9 3-methyl-2-oxobutanoate dehydrogenase subunit VorB compare
MMP_RS06570 +0.8 1.6 DUF190 domain-containing protein compare
MMP_RS08665 +0.8 4.8 hypothetical protein compare
MMP_RS03340 +0.8 0.7 ABC transporter ATP-binding protein compare
MMP_RS08345 +0.8 3.4 4Fe-4S binding protein compare
MMP_RS00655 +0.7 1.9 hypothetical protein compare
MMP_RS01540 +0.7 1.8 DUF504 domain-containing protein compare
MMP_RS00155 +0.7 1.7 heavy metal-binding domain-containing protein compare
MMP_RS08285 +0.7 2.7 serine/threonine protein kinase compare
MMP_RS07550 +0.7 4.4 L-serine ammonia-lyase iron-sulfur-dependent subunit alpha compare
MMP_RS03495 +0.7 2.7 Na/Pi cotransporter family protein compare
MMP_RS02790 +0.7 0.7 class III signal peptide-containing protein compare
MMP_RS05090 +0.7 2.5 CO dehydrogenase/CO-methylating acetyl-CoA synthase complex subunit beta compare
MMP_RS08930 +0.7 1.1 hypothetical protein compare
MMP_RS00665 +0.7 1.8 hypothetical protein compare
MMP_RS08260 +0.7 3.2 DUF99 family protein compare
MMP_RS08555 +0.6 1.4 hypothetical protein compare
MMP_RS03150 +0.6 3.3 phosphoglycerate mutase compare
MMP_RS00545 +0.6 1.4 XRE family transcriptional regulator compare
MMP_RS09055 +0.6 0.6 CAP domain-containing protein compare
MMP_RS00380 +0.6 2.2 P-II family nitrogen regulator compare
MMP_RS03540 +0.6 2.2 DUF2178 domain-containing protein compare
MMP_RS07560 +0.6 1.6 prefoldin subunit alpha compare
MMP_RS04100 +0.6 1.2 hypothetical protein compare
MMP_RS06440 +0.6 1.6 CBS domain-containing protein compare
MMP_RS02300 +0.6 2.2 NAD(P)H-dependent oxidoreductase compare
MMP_RS06150 +0.6 2.7 hypothetical protein compare
MMP_RS06910 +0.6 3.5 RlmF-related methyltransferase compare
MMP_RS04205 +0.6 1.9 carboxymuconolactone decarboxylase family protein compare
MMP_RS05505 +0.6 2.0 class IV adenylate cyclase compare
MMP_RS08995 +0.6 0.6 hypothetical protein compare
MMP_RS00290 +0.5 1.7 hypothetical protein compare
MMP_RS08340 +0.5 1.6 4Fe-4S binding protein compare
MMP_RS04015 +0.5 0.9 hypothetical protein compare
MMP_RS08275 +0.5 2.3 hypothetical protein compare
MMP_RS05175 +0.5 2.2 hypothetical protein compare
MMP_RS01620 +0.5 1.5 hypothetical protein compare
MMP_RS08390 +0.5 1.1 DUF5400 domain-containing protein compare
MMP_RS00640 +0.5 2.0 ABC transporter substrate-binding protein compare
MMP_RS08850 +0.5 3.1 hypothetical protein compare
MMP_RS05315 +0.5 0.7 hypothetical protein compare
MMP_RS00650 +0.5 1.6 ABC transporter ATP-binding protein compare
MMP_RS05435 +0.5 1.7 5'/3'-nucleotidase SurE compare
MMP_RS04165 +0.5 1.8 TetR/AcrR family transcriptional regulator compare
MMP_RS00660 +0.5 2.7 alkaline phosphatase family protein compare
MMP_RS07620 +0.5 1.0 energy-coupling factor ABC transporter substrate-binding protein compare
MMP_RS03785 +0.5 1.4 cupin domain-containing protein compare
MMP_RS08410 +0.5 1.9 DUF169 domain-containing protein compare
MMP_RS02470 +0.5 0.7 helix-turn-helix transcriptional regulator compare
MMP_RS08675 +0.5 0.8 class III signal peptide-containing protein compare
MMP_RS01485 +0.5 2.1 right-handed parallel beta-helix repeat-containing protein compare
MMP_RS06545 +0.5 0.8 ferredoxin family protein compare
MMP_RS02495 +0.5 0.6 hypothetical protein compare
MMP_RS04885 +0.5 2.7 sulfite exporter TauE/SafE family protein compare
MMP_RS00865 +0.5 1.0 SLC13 family permease compare
MMP_RS07925 +0.5 1.5 haloacid dehalogenase compare
MMP_RS02415 +0.5 0.7 site-specific integrase compare
MMP_RS01080 +0.5 1.8 DUF2202 domain-containing protein compare
MMP_RS02310 +0.5 0.7 RimK-like ATPgrasp N-terminal domain-containing protein compare
MMP_RS08835 +0.4 1.6 H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein compare
MMP_RS01635 +0.4 1.5 thiamine pyrophosphate-dependent enzyme compare
MMP_RS03320 +0.4 0.9 metal-dependent transcriptional regulator compare
MMP_RS03430 +0.4 2.0 bile acid:sodium symporter family protein compare
MMP_RS08775 +0.4 1.0 methanogenesis marker 9 domain-containing protein compare
MMP_RS01940 +0.4 0.9 MoxR family ATPase compare
MMP_RS04875 +0.4 1.5 energy-converting hydrogenase B subunit P compare
MMP_RS00120 +0.4 0.7 LysR family transcriptional regulator compare
MMP_RS04050 +0.4 1.4 hypothetical protein compare
MMP_RS01150 +0.4 1.5 aldo/keto reductase compare
MMP_RS01650 +0.4 0.3 sulfurtransferase TusA family protein compare
MMP_RS04060 +0.4 1.4 hypothetical protein compare
MMP_RS00975 +0.4 2.0 HD domain-containing protein compare
MMP_RS00645 +0.4 1.7 iron ABC transporter permease compare
MMP_RS06665 +0.4 1.6 glycogen/starch synthase compare
MMP_RS00435 +0.4 2.4 CPBP family intramembrane metalloprotease compare
MMP_RS02550 +0.4 1.1 helix-turn-helix transcriptional regulator compare
MMP_RS05675 +0.4 1.1 phosphate ABC transporter ATP-binding protein PstB compare
MMP_RS05970 +0.4 1.2 class II SORL domain-containing protein compare
MMP_RS01290 +0.4 1.8 class III signal peptide-containing protein compare
MMP_RS07625 +0.4 0.6 cobalt ECF transporter T component CbiQ compare
MMP_RS02835 +0.4 1.0 CGGC domain-containing protein compare
MMP_RS06530 +0.4 1.0 bifunctional hexulose-6-phosphate synthase/ribonuclease regulator compare
MMP_RS01275 +0.4 1.3 class III signal peptide-containing protein compare
MMP_RS01065 +0.4 2.0 alpha/beta hydrolase compare
MMP_RS08945 +0.4 1.8 hypothetical protein compare
MMP_RS06535 +0.4 0.8 2-oxoacid:acceptor oxidoreductase family protein compare
MMP_RS07150 +0.4 1.5 MTH895/ArsE family thioredoxin-like protein compare
MMP_RS00395 +0.4 0.5 MGMT family protein compare
MMP_RS05895 +0.4 2.2 metallophosphoesterase compare
MMP_RS02765 +0.4 1.3 ABC transporter ATP-binding protein compare
MMP_RS04405 +0.4 1.9 hypothetical protein compare
MMP_RS07155 +0.4 1.5 MFS transporter compare
MMP_RS02370 +0.4 0.8 NifB/NifX family molybdenum-iron cluster-binding protein compare
MMP_RS01930 +0.4 2.5 hypothetical protein compare
MMP_RS08235 +0.4 1.2 hypothetical protein compare
MMP_RS01855 +0.4 1.4 2-hydroxyacyl-CoA dehydratase family protein compare
MMP_RS02305 +0.4 1.7 DUF378 domain-containing protein compare
MMP_RS08750 +0.4 0.5 hypothetical protein compare
MMP_RS07805 +0.4 1.7 ABC transporter permease compare
MMP_RS06430 +0.4 1.0 6-carboxytetrahydropterin synthase QueD compare
MMP_RS06075 +0.4 1.1 class I SAM-dependent methyltransferase compare
MMP_RS06320 +0.4 1.4 hypothetical protein compare
MMP_RS00530 +0.4 1.0 tRNA pseudouridine(54/55) synthase Pus10 compare
MMP_RS03575 +0.4 2.0 ECF transporter S component compare
MMP_RS02915 +0.4 1.0 amino acid ABC transporter permease compare
MMP_RS00085 +0.4 1.6 DNA cytosine methyltransferase compare
MMP_RS05080 +0.4 1.5 acetyl-CoA decarbonylase/synthase complex subunit delta compare
MMP_RS06065 +0.4 2.2 iron ABC transporter substrate-binding protein compare
MMP_RS01945 +0.4 1.8 DUF4350 domain-containing protein compare
MMP_RS06250 +0.4 1.2 hypothetical protein compare
MMP_RS00825 +0.4 1.1 fumarylacetoacetate hydrolase family protein compare
MMP_RS02935 +0.4 1.0 A24 family peptidase compare
MMP_RS00240 +0.4 2.0 type II secretion system F family protein compare
MMP_RS04120 +0.4 1.5 hypothetical protein compare
MMP_RS02230 +0.4 2.3 sodium-dependent transporter compare
MMP_RS09050 +0.3 0.5 CAP domain-containing protein compare
MMP_RS02910 +0.3 1.3 ABC transporter substrate-binding protein compare
MMP_RS05235 +0.3 1.5 exodeoxyribonuclease III compare
MMP_RS09065 +0.3 2.0 hypothetical protein compare
MMP_RS04520 +0.3 1.0 nucleoside deaminase compare
MMP_RS06990 +0.3 1.0 CatB-related O-acetyltransferase compare
MMP_RS01435 +0.3 1.0 DMT family transporter compare
MMP_RS01630 +0.3 1.7 N-glycosylase/DNA lyase compare
MMP_RS05960 +0.3 1.4 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS01115 +0.3 1.6 molybdopterin molybdotransferase MoeA compare
MMP_RS06590 +0.3 0.6 GNAT family N-acetyltransferase compare
MMP_RS02540 +0.3 1.2 DUF2283 domain-containing protein compare
MMP_RS08630 +0.3 1.3 archaellar assembly protein FlaJ compare
MMP_RS08380 +0.3 1.1 phosphatase PAP2 family protein compare
MMP_RS01085 +0.3 0.5 hypothetical protein compare
MMP_RS02580 +0.3 1.1 cupin domain-containing protein compare
MMP_RS08770 +0.3 1.4 hypothetical protein compare
MMP_RS02170 +0.3 1.2 CBS domain-containing protein compare
MMP_RS03545 +0.3 1.3 ATP-binding protein compare
MMP_RS03480 +0.3 1.7 SulP family inorganic anion transporter compare
MMP_RS02555 +0.3 2.4 AIPR family protein compare
MMP_RS07135 +0.3 1.5 coenzyme F420 hydrogenase subunit beta compare
MMP_RS01055 +0.3 0.9 hypothetical protein compare
MMP_RS00990 +0.3 1.3 hypothetical protein compare
MMP_RS07125 +0.3 0.6 coenzyme F420-reducing hydrogenase FrhD protein compare
MMP_RS08830 +0.3 0.8 GTP-binding protein compare
MMP_RS05780 +0.3 1.5 multidrug resistance efflux transporter family protein compare
MMP_RS08610 +0.3 1.2 flagellar protein F compare
MMP_RS08455 +0.3 0.9 multiprotein bridging factor aMBF1 compare
MMP_RS05995 +0.3 1.6 FprA family A-type flavoprotein compare
MMP_RS00325 +0.3 0.4 RNA-binding protein compare
MMP_RS04315 +0.3 1.0 corrinoid protein compare
MMP_RS07350 +0.3 0.5 preprotein translocase subunit Sec61beta compare
MMP_RS05820 +0.3 0.8 RNA-binding transcriptional accessory protein compare
MMP_RS00385 +0.3 0.8 P-II family nitrogen regulator compare
MMP_RS00105 +0.3 1.3 hypothetical protein compare
MMP_RS02320 +0.3 1.7 glutamate-cysteine ligase family protein compare
MMP_RS03980 +0.3 1.6 hypothetical protein compare
MMP_RS05275 +0.3 1.8 AI-2E family transporter compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source L-Alanine in Methanococcus maripaludis S2

For nitrogen source L-Alanine across organisms