Experiment set6IT084 for Cupriavidus basilensis FW507-4G11

Compare to:

R2A with Cobalt chloride hexahydrate 0.3 mM

200 most detrimental genes:

  gene name fitness t score description  
RR42_RS17560 +5.7 45.7 Fur family transcriptional regulator compare
RR42_RS26935 +4.3 11.2 farnesyl-diphosphate farnesyltransferase compare
RR42_RS31530 +3.5 14.9 histidine kinase compare
RR42_RS21435 +3.4 9.8 hypothetical protein compare
RR42_RS05860 +3.3 10.7 phospho-2-dehydro-3-deoxyheptonate aldolase compare
RR42_RS19005 +3.2 10.9 3-dehydroquinate synthase compare
RR42_RS06630 +3.1 2.1 integration host factor subunit alpha compare
RR42_RS21095 +3.0 10.3 GntR family transcriptional regulator compare
RR42_RS17055 +3.0 13.2 LuxR family transcriptional regulator compare
RR42_RS17565 +2.8 17.0 LysR family transcriptional regulator compare
RR42_RS19475 +2.8 17.7 general secretion pathway protein compare
RR42_RS18150 +2.7 14.9 long-chain fatty acid--CoA ligase compare
RR42_RS02045 +2.7 15.8 GTPase compare
RR42_RS17060 +2.6 20.2 histidine kinase compare
RR42_RS13735 +2.6 10.2 ADP-heptose--LPS heptosyltransferase compare
RR42_RS35445 +2.5 5.7 ArsR family transcriptional regulator compare
RR42_RS04895 +2.5 14.7 serine/threonine protein phosphatase compare
RR42_RS09260 +2.5 5.8 TetR family transcriptional regulator compare
RR42_RS17355 +2.3 3.4 hypothetical protein compare
RR42_RS35865 +2.2 4.1 membrane protein compare
RR42_RS15415 +2.1 6.2 membrane protein compare
RR42_RS30955 +2.1 5.3 histidine kinase compare
RR42_RS33180 +2.1 10.2 hypothetical protein compare
RR42_RS11930 +2.0 7.0 succinyldiaminopimelate aminotransferase compare
RR42_RS15410 +2.0 11.6 membrane protein compare
RR42_RS17635 +1.8 6.5 magnesium transporter CorA compare
RR42_RS15050 +1.6 7.9 DNA polymerase I compare
RR42_RS17930 +1.6 5.7 RNA pyrophosphohydrolase compare
RR42_RS09045 +1.6 9.9 peptidylprolyl isomerase compare
RR42_RS06125 +1.6 4.9 phosphogluconate dehydratase compare
RR42_RS13515 +1.6 5.5 membrane protein compare
RR42_RS07905 +1.6 8.1 phytoene synthase compare
RR42_RS04265 +1.6 7.6 chemotaxis protein CheY compare
RR42_RS35645 +1.6 4.5 MFS transporter compare
RR42_RS21470 +1.6 2.3 hypothetical protein compare
RR42_RS20195 +1.5 1.8 ATPase F0F1 compare
RR42_RS01565 +1.5 6.0 hypothetical protein compare
RR42_RS17645 +1.5 5.4 shikimate dehydrogenase compare
RR42_RS06355 +1.5 3.0 Fe-S cluster assembly protein HesB compare
RR42_RS04260 +1.5 4.5 chemotaxis protein compare
RR42_RS13130 +1.5 3.0 membrane protein compare
RR42_RS01720 +1.5 3.6 membrane protein compare
RR42_RS30965 +1.4 4.2 hypothetical protein compare
RR42_RS14775 +1.4 7.3 peptidase M48 compare
RR42_RS03095 +1.4 2.3 succinyl-CoA synthetase subunit beta compare
RR42_RS21755 +1.4 1.8 shikimate dehydrogenase compare
RR42_RS13055 +1.4 6.3 NAD-dependent protein deacylase compare
RR42_RS19045 +1.4 2.0 frataxin compare
RR42_RS31435 +1.4 1.8 hypothetical protein compare
RR42_RS36985 +1.4 6.5 amino acid ABC transporter substrate-binding protein compare
RR42_RS31535 +1.4 3.3 transcriptional regulator compare
RR42_RS04735 +1.3 2.2 hypothetical protein compare
RR42_RS12925 +1.3 3.6 ATPase compare
RR42_RS02840 +1.3 3.9 cation transporter compare
RR42_RS08180 +1.3 1.8 hypothetical protein compare
RR42_RS16910 +1.3 2.2 histidine utilization protein HutD compare
RR42_RS13830 +1.3 2.0 hypothetical protein compare
RR42_RS04255 +1.3 2.9 chemotaxis protein CheW compare
RR42_RS07410 +1.3 5.3 peptidase S11 compare
RR42_RS28955 +1.3 4.8 transcriptional regulator compare
RR42_RS04145 +1.2 1.0 peptidase A24 compare
RR42_RS15420 +1.2 3.5 hypothetical protein compare
RR42_RS04405 +1.2 5.1 cyanophycin synthetase compare
RR42_RS10150 +1.2 2.4 hypothetical protein compare
RR42_RS19655 +1.2 1.8 tRNA-Ala compare
RR42_RS17165 +1.2 2.4 hypothetical protein compare
RR42_RS21085 +1.2 6.6 3-isopropylmalate dehydratase compare
RR42_RS33425 +1.2 2.9 cobalt-zinc-cadmium resistance protein compare
RR42_RS25510 +1.2 1.9 short-chain dehydrogenase compare
RR42_RS14155 +1.2 8.3 pseudouridine synthase compare
RR42_RS18485 +1.2 1.4 glutaredoxin compare
RR42_RS17715 +1.2 2.6 thiol peroxidase compare
RR42_RS06345 +1.2 3.2 hypothetical protein compare
RR42_RS13380 +1.2 5.5 microcin ABC transporter permease compare
RR42_RS30710 +1.2 5.4 TetR family transcriptional regulator compare
RR42_RS19685 +1.2 1.4 thiosulfate oxidation carrier complex protein SoxZ compare
RR42_RS20655 +1.2 4.6 multidrug transporter compare
RR42_RS04250 +1.1 3.1 chemotaxis protein CheY compare
RR42_RS04410 +1.1 5.7 cyanophycin synthetase compare
RR42_RS13385 +1.1 5.3 peptide ABC transporter substrate-binding protein compare
RR42_RS32590 +1.1 1.9 cytochrome o ubiquinol oxidase subunit III compare
RR42_RS13375 +1.1 4.6 peptide ABC transporter permease compare
RR42_RS15865 +1.1 1.9 uracil phosphoribosyltransferase compare
RR42_RS19760 +1.1 3.2 hypothetical protein compare
RR42_RS14885 +1.1 2.5 DNA-directed RNA polymerase sigma-70 factor compare
RR42_RS28125 +1.1 1.9 hypothetical protein compare
RR42_RS22275 +1.1 1.9 hypothetical protein compare
RR42_RS00510 +1.1 1.6 transcriptional regulator compare
RR42_RS28615 +1.1 1.8 ABC transporter substrate-binding protein compare
RR42_RS35630 +1.1 3.1 ArsR family transcriptional regulator compare
RR42_RS08185 +1.1 2.8 hypothetical protein compare
RR42_RS07150 +1.1 1.3 hypothetical protein compare
RR42_RS37410 +1.0 4.1 PaaX family transcriptional regulator compare
RR42_RS23650 +1.0 2.5 flagellar protein compare
RR42_RS01690 +1.0 1.8 ferredoxin compare
RR42_RS19010 +1.0 5.8 shikimate kinase compare
RR42_RS27120 +1.0 1.5 amino acid ABC transporter permease compare
RR42_RS33415 +1.0 3.8 RND transporter MFP subunit compare
RR42_RS10195 +1.0 2.1 hypothetical protein compare
RR42_RS05325 +1.0 5.7 adenine deaminase compare
RR42_RS27995 +1.0 2.9 RelE toxin compare
RR42_RS23040 +1.0 3.0 hypothetical protein compare
RR42_RS29340 +1.0 3.8 hypothetical protein compare
RR42_RS35770 +1.0 2.9 flagellar biosynthesis protein FlhB compare
RR42_RS02935 +1.0 2.5 malonate decarboxylase subunit epsilon compare
RR42_RS10675 +1.0 3.5 hypothetical protein compare
RR42_RS19645 +1.0 1.9 DNA topoisomerase compare
RR42_RS08945 +1.0 1.0 hypothetical protein compare
RR42_RS03320 +1.0 2.1 transcriptional regulator compare
RR42_RS25650 +1.0 0.6 hypothetical protein compare
RR42_RS36975 +1.0 2.8 polar amino acid ABC transporter permease compare
RR42_RS31830 +1.0 1.8 short-chain dehydrogenase compare
RR42_RS28720 +1.0 2.2 hypothetical protein compare
RR42_RS18950 +1.0 4.7 hypothetical protein compare
RR42_RS31695 +1.0 2.8 hypothetical protein compare
RR42_RS22940 +1.0 1.6 TetR family transcriptional regulator compare
RR42_RS06475 +1.0 5.3 glycerol acyltransferase compare
RR42_RS21080 +1.0 1.7 3-isopropylmalate dehydratase compare
RR42_RS33410 +1.0 5.4 cytochrome C peroxidase compare
RR42_RS19460 +1.0 3.6 GCN5 family acetyltransferase compare
RR42_RS06700 +1.0 2.8 hypothetical protein compare
RR42_RS05115 +1.0 1.9 LysR family transcriptional regulator compare
RR42_RS37240 +1.0 1.2 hypothetical protein compare
RR42_RS09835 +1.0 1.6 chemotaxis protein compare
RR42_RS19830 +0.9 2.0 LysR family transcriptional regulator compare
RR42_RS31920 +0.9 1.3 acetyl-CoA acetyltransferase compare
RR42_RS37420 +0.9 2.7 AraC family transcriptional regulator compare
RR42_RS02870 +0.9 2.9 RNA helicase compare
RR42_RS09060 +0.9 0.7 glucose-6-phosphate isomerase compare
RR42_RS35660 +0.9 3.1 hypothetical protein compare
RR42_RS19920 +0.9 4.3 membrane protein compare
RR42_RS29505 +0.9 2.2 hypothetical protein compare
RR42_RS13210 +0.9 5.9 porin compare
RR42_RS19895 +0.9 1.4 elongation factor GreAB compare
RR42_RS34935 +0.9 1.8 cytochrome C oxidase subunit IV compare
RR42_RS36715 +0.9 3.2 alanine acetyltransferase compare
RR42_RS33385 +0.9 4.4 XpsR family transcriptional regulator compare
RR42_RS16940 +0.9 2.5 ABC transporter permease compare
RR42_RS23675 +0.9 3.4 hypothetical protein compare
RR42_RS06675 +0.9 3.6 hypothetical protein compare
RR42_RS24760 +0.9 1.2 hypothetical protein compare
RR42_RS10465 +0.9 1.4 hypothetical protein compare
RR42_RS16835 +0.9 2.8 6-phosphogluconate dehydrogenase compare
RR42_RS05210 +0.9 4.6 malic enzyme compare
RR42_RS27480 +0.9 1.6 AraC family transcriptional regulator compare
RR42_RS04655 +0.9 5.3 glycosyl transferase compare
RR42_RS21450 +0.9 1.0 hypothetical protein compare
RR42_RS32385 +0.9 2.7 citrate synthase compare
RR42_RS06710 +0.9 1.9 hypothetical protein compare
RR42_RS06470 +0.9 1.4 hypothetical protein compare
RR42_RS29285 +0.9 1.4 hypothetical protein compare
RR42_RS00765 +0.9 2.4 sulfurtransferase compare
RR42_RS08995 +0.9 3.4 hypothetical protein compare
RR42_RS25400 +0.8 2.1 MarR family transcriptional regulator compare
RR42_RS12730 +0.8 2.4 membrane protein compare
RR42_RS11580 +0.8 2.1 hypothetical protein compare
RR42_RS36305 +0.8 2.2 TetR family transcriptional regulator compare
RR42_RS27190 +0.8 1.7 chemotaxis protein compare
RR42_RS11085 +0.8 3.3 acetyl-CoA acetyltransferase compare
RR42_RS03005 +0.8 1.5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase compare
RR42_RS27475 +0.8 1.3 phospholipid-binding protein compare
RR42_RS00725 +0.8 2.1 hypothetical protein compare
RR42_RS35900 +0.8 3.6 hypothetical protein compare
RR42_RS06665 +0.8 3.8 reverse transcriptase compare
RR42_RS11805 +0.8 1.3 ribonuclease HII compare
RR42_RS22360 +0.8 1.7 hypothetical protein compare
RR42_RS05475 +0.8 4.8 ABC transporter permease compare
RR42_RS20440 +0.8 1.2 histidine kinase compare
RR42_RS20610 +0.8 3.0 tripartite tricarboxylate transporter TctA compare
RR42_RS07310 +0.8 2.2 hypothetical protein compare
RR42_RS13200 +0.8 4.6 stationary phase survival protein SurE compare
RR42_RS07380 +0.8 1.5 dihydrolipoamide dehydrogenase compare
RR42_RS04415 +0.8 3.4 ABC transporter compare
RR42_RS06225 +0.8 4.2 phosphoesterase compare
RR42_RS10910 +0.8 4.2 aminodeoxychorismate lyase compare
RR42_RS19635 +0.8 1.3 hypothetical protein compare
RR42_RS10105 +0.8 1.8 phosphonate ABC transporter compare
RR42_RS07420 +0.8 4.1 GntR family transcriptional regulator compare
RR42_RS15440 +0.8 4.5 transporter compare
RR42_RS31275 +0.8 3.8 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) (from data) compare
RR42_RS15665 +0.8 1.8 sulfurtransferase compare
RR42_RS37400 +0.8 0.9 6-phosphogluconolactonase compare
RR42_RS12550 +0.8 1.6 hypothetical protein compare
RR42_RS11145 +0.8 4.5 ABC transporter permease compare
RR42_RS30705 +0.8 5.6 FAD-containing monooxygenase EthA compare
RR42_RS22955 +0.8 3.5 isocitrate dehydrogenase compare
RR42_RS13610 +0.8 2.0 IclR family transcriptional regulator compare
RR42_RS19845 +0.8 2.2 hypothetical protein compare
RR42_RS02750 +0.8 3.0 mannose-1-phosphate guanylyltransferase compare
RR42_RS32850 +0.8 1.9 universal stress protein UspA compare
RR42_RS23205 +0.8 0.8 hypothetical protein compare
RR42_RS14520 +0.8 1.1 mobilization protein compare
RR42_RS24490 +0.8 1.7 hypothetical protein compare
RR42_RS37290 +0.8 3.9 PadR family transcriptional regulator compare
RR42_RS07325 +0.8 3.9 exodeoxyribonuclease III compare
RR42_RS36170 +0.8 1.9 hypothetical protein compare
RR42_RS33850 +0.8 1.5 hypothetical protein compare
RR42_RS13810 +0.8 2.9 glycerol kinase compare
RR42_RS14955 +0.8 2.7 hypothetical protein compare
RR42_RS08805 +0.8 1.4 nitrate reductase compare


Specific Phenotypes

For 22 genes in this experiment

For stress Cobalt chloride hexahydrate in Cupriavidus basilensis FW507-4G11

For stress Cobalt chloride hexahydrate across organisms