Experiment set6IT068 for Klebsiella michiganensis M5al

Compare to:

Thymidine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS10785 +2.2 14.6 transcriptional regulator conserved
BWI76_RS08825 +2.0 6.7 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS25285 +1.8 3.2 HPr family phosphocarrier protein compare
BWI76_RS06595 +1.7 5.3 hypothetical protein compare
BWI76_RS17370 +1.6 4.4 nitrate transporter NasD compare
BWI76_RS17385 +1.6 8.7 nitrate regulatory protein conserved
BWI76_RS18335 +1.5 9.6 DNA-binding response regulator compare
BWI76_RS17375 +1.5 2.4 nitrate ABC transporter, permease protein compare
BWI76_RS22815 +1.4 12.0 hybrid sensor histidine kinase/response regulator compare
BWI76_RS04275 +1.4 8.7 molybdopterin adenylyltransferase compare
BWI76_RS08780 +1.4 6.7 ABC transporter conserved
BWI76_RS08815 +1.4 4.7 cyclic pyranopterin phosphate synthase compare
BWI76_RS08835 +1.4 5.8 molybdopterin guanine dinucleotide biosynthesis protein MoaE compare
BWI76_RS09085 +1.3 7.6 molybdopterin molybdenumtransferase MoeA compare
BWI76_RS23270 +1.3 9.5 phosphoenolpyruvate--protein phosphotransferase PtsP compare
BWI76_RS17380 +1.3 7.0 nitrate transporter component compare
BWI76_RS20785 +1.3 2.1 ethanolamine utilization protein EutJ compare
BWI76_RS21675 +1.2 2.3 hypothetical protein compare
BWI76_RS00330 +1.2 8.1 molybdenum cofactor guanylyltransferase compare
BWI76_RS11990 +1.2 5.2 exoribonuclease II compare
BWI76_RS06540 +1.2 2.3 DNA-binding protein HU-beta compare
BWI76_RS01325 +1.2 2.5 twin-arginine translocase subunit TatB compare
BWI76_RS19770 +1.1 2.4 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS04135 +1.1 7.9 thymidine phosphorylase conserved
BWI76_RS01330 +1.1 2.5 twin-arginine translocase subunit TatC compare
BWI76_RS11635 +1.0 1.8 ABC transporter compare
BWI76_RS24720 +1.0 1.3 hypothetical protein compare
BWI76_RS05570 +1.0 1.5 hypothetical protein compare
BWI76_RS09080 +0.9 1.8 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS17805 +0.9 1.5 membrane protein compare
BWI76_RS06935 +0.9 4.4 co-chaperone YbbN compare
BWI76_RS02570 +0.9 5.2 transcriptional regulator compare
BWI76_RS16360 +0.9 1.6 electron transport complex subunit RsxB compare
BWI76_RS16490 +0.9 2.3 glutaredoxin compare
BWI76_RS20310 +0.9 2.0 hypothetical protein compare
BWI76_RS21165 +0.9 1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS21200 +0.9 2.6 aldose epimerase compare
BWI76_RS01630 +0.9 1.2 16S ribosomal RNA compare
BWI76_RS26875 +0.8 1.6 dipeptide ABC transporter permease DppC compare
BWI76_RS09625 +0.8 1.4 hypothetical protein compare
BWI76_RS11335 +0.8 1.4 tautomerase compare
BWI76_RS26150 +0.8 3.3 molecular chaperone Hsp33 compare
BWI76_RS20720 +0.8 1.5 hypothetical protein compare
BWI76_RS21460 +0.8 1.4 translation inhibitor protein RaiA compare
BWI76_RS18080 +0.8 2.3 protein YebE compare
BWI76_RS07905 +0.8 3.8 trimethylamine-N-oxide reductase (cytochrome c) compare
BWI76_RS15260 +0.8 1.5 hypothetical protein compare
BWI76_RS27425 +0.8 1.1 DNA-directed RNA polymerase subunit omega compare
BWI76_RS26245 +0.8 1.9 transcriptional regulator compare
BWI76_RS17795 +0.8 1.8 ribonuclease D compare
BWI76_RS11980 +0.8 1.2 DeoR family transcriptional regulator compare
BWI76_RS14755 +0.8 1.3 SIS domain-containing protein compare
BWI76_RS18195 +0.8 3.9 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
BWI76_RS09050 +0.7 1.7 MFS transporter compare
BWI76_RS24180 +0.7 1.3 hypothetical protein compare
BWI76_RS00725 +0.7 3.1 periplasmic repressor CpxP compare
BWI76_RS14065 +0.7 0.9 hypothetical protein compare
BWI76_RS07955 +0.7 2.3 nucleoside diphosphate kinase regulator compare
BWI76_RS26290 +0.7 3.0 glycerol-3-phosphate ABC transporter ATP-binding protein compare
BWI76_RS10465 +0.7 1.9 hypothetical protein compare
BWI76_RS22960 +0.7 1.6 YgdI/YgdR family lipoprotein compare
BWI76_RS22265 +0.7 2.9 NADH:flavorubredoxin oxidoreductase compare
BWI76_RS26185 +0.7 2.5 thiosulfate sulfurtransferase compare
BWI76_RS05045 +0.7 2.6 general secretion pathway protein GspM compare
BWI76_RS13470 +0.7 2.0 transporter compare
BWI76_RS20395 +0.7 3.9 flagella biosynthesis regulator compare
BWI76_RS01585 +0.7 3.1 transcriptional regulator compare
BWI76_RS18190 +0.7 2.6 carboxy-S-adenosyl-L-methionine synthase CmoA compare
BWI76_RS25220 +0.7 2.7 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS03025 +0.7 2.1 N-acetyltransferase compare
BWI76_RS01580 +0.7 1.7 hypothetical protein compare
BWI76_RS10540 +0.7 2.7 allantoinase compare
BWI76_RS16315 +0.7 1.3 SirA-like protein compare
BWI76_RS06060 +0.7 2.3 DNA-binding response regulator compare
BWI76_RS24035 +0.7 1.8 hypothetical protein compare
BWI76_RS11300 +0.7 1.0 cupin compare
BWI76_RS12585 +0.7 2.1 transcriptional regulator compare
BWI76_RS06780 +0.7 2.9 MexE family multidrug efflux RND transporter periplasmic adaptor subunit compare
BWI76_RS06905 +0.7 3.8 Cu+ exporting ATPase compare
BWI76_RS13710 +0.7 2.0 benzoate 1,2-dioxygenase small subunit compare
BWI76_RS09165 +0.7 1.4 phosphatase YbjI compare
BWI76_RS11435 +0.7 1.1 hypothetical protein compare
BWI76_RS20730 +0.7 1.3 hypothetical protein compare
BWI76_RS18125 +0.7 1.8 murein DD-endopeptidase MepM compare
BWI76_RS10395 +0.7 3.6 cold-shock protein compare
BWI76_RS10260 +0.6 1.9 creatinase compare
BWI76_RS27875 +0.6 0.9 membrane protein compare
BWI76_RS07510 +0.6 1.8 hypothetical protein compare
BWI76_RS05655 +0.6 1.6 hypothetical protein compare
BWI76_RS11820 +0.6 0.9 short-chain dehydrogenase/reductase SDR compare
BWI76_RS21740 +0.6 1.8 transcriptional regulator, LysR family protein compare
BWI76_RS09015 +0.6 1.6 aldo/keto reductase compare
BWI76_RS15970 +0.6 1.7 carboxypeptidase M32 compare
BWI76_RS20715 +0.6 1.4 RpoE-regulated lipoprotein compare
BWI76_RS11275 +0.6 3.9 sensor protein PhoQ compare
BWI76_RS13480 +0.6 1.2 XRE family transcriptional regulator compare
BWI76_RS09615 +0.6 1.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS17330 +0.6 1.7 nitrate reductase subunit beta compare
BWI76_RS24390 +0.6 2.4 hypothetical protein compare
BWI76_RS16075 +0.6 1.1 oxidoreductase compare
BWI76_RS12040 +0.6 0.9 hypothetical protein compare
BWI76_RS11610 +0.6 1.0 glutamate dehydrogenase compare
BWI76_RS15985 +0.6 2.2 LysR family transcriptional regulator compare
BWI76_RS24740 +0.6 1.4 GntR family transcriptional regulator compare
BWI76_RS18230 +0.6 2.4 trehalose-6-phosphate synthase compare
BWI76_RS13950 +0.6 1.3 hypothetical protein compare
BWI76_RS16450 +0.6 3.1 fusaric acid resistance protein compare
BWI76_RS19785 +0.6 1.4 microcin C ABC transporter permease YejB compare
BWI76_RS11180 +0.6 3.6 hypothetical protein compare
BWI76_RS16150 +0.6 1.7 IclR family transcriptional regulator compare
BWI76_RS20245 +0.6 1.7 transketolase subunit B compare
BWI76_RS12870 +0.6 1.7 putative phytanoyl-CoA dioxygenase compare
BWI76_RS21375 +0.6 1.0 autonomous glycyl radical cofactor GrcA compare
BWI76_RS13380 +0.6 2.0 hypothetical protein compare
BWI76_RS16025 +0.6 1.3 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS03585 +0.6 2.0 ethanolamine utilization protein EutN compare
BWI76_RS17920 +0.6 0.9 23S rRNA (guanine(745)-N(1))-methyltransferase compare
BWI76_RS16335 +0.6 1.1 division septum protein Blr compare
BWI76_RS00830 +0.6 3.9 metal-binding protein ZinT compare
BWI76_RS07730 +0.6 1.0 iron-enterobactin transporter membrane protein compare
BWI76_RS10475 +0.6 1.7 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS21410 +0.6 2.3 lipoprotein compare
BWI76_RS15760 +0.6 1.0 hypothetical protein compare
BWI76_RS19390 +0.6 1.5 LysR family transcriptional regulator compare
BWI76_RS04655 +0.6 0.7 shikimate dehydrogenase compare
BWI76_RS10995 +0.6 3.2 lipoprotein compare
BWI76_RS08795 +0.6 2.4 DNA-binding response regulator compare
BWI76_RS23030 +0.6 1.2 cobalamin biosynthesis protein CbiM compare
BWI76_RS09570 +0.6 2.0 hydroxylamine reductase compare
BWI76_RS27760 +0.5 1.2 lactam utilization protein LamB compare
BWI76_RS00335 +0.5 2.0 hypothetical protein compare
BWI76_RS08590 +0.5 2.9 zinc transporter ZitB compare
BWI76_RS19275 +0.5 1.8 DNA-binding response regulator compare
BWI76_RS16445 +0.5 1.2 auxiliary transporter membrane fusion protein compare
BWI76_RS16370 +0.5 1.6 electron transport complex subunit D compare
BWI76_RS13630 +0.5 2.0 ABC transporter compare
BWI76_RS23825 +0.5 3.6 hypothetical protein compare
BWI76_RS06400 +0.5 0.9 oxidative-stress-resistance chaperone compare
BWI76_RS26620 +0.5 0.7 Fe-S biogenesis protein NfuA compare
BWI76_RS16095 +0.5 1.0 thiamine biosynthesis protein ApbE compare
BWI76_RS25375 +0.5 1.2 hypothetical protein compare
BWI76_RS17835 +0.5 2.3 sugar ABC transporter permease compare
BWI76_RS15915 +0.5 3.1 YnfC family lipoprotein compare
BWI76_RS12480 +0.5 2.2 TIGR01620 family protein compare
BWI76_RS22210 +0.5 1.7 murein transglycosylase B compare
BWI76_RS07640 +0.5 1.1 short chain dehydrogenase compare
BWI76_RS11060 +0.5 1.0 septum formation inhibitor Maf compare
BWI76_RS26380 +0.5 2.7 decarboxylase compare
BWI76_RS06200 +0.5 1.5 hypothetical protein compare
BWI76_RS23120 +0.5 0.8 propanediol dehydratase medium subunit compare
BWI76_RS08310 +0.5 1.5 potassium-transporting ATPase subunit C compare
BWI76_RS14835 +0.5 0.7 hypothetical protein compare
BWI76_RS01195 +0.5 0.6 membrane protein compare
BWI76_RS27200 +0.5 1.8 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL compare
BWI76_RS26755 +0.5 3.6 peptidase M16 compare
BWI76_RS04440 +0.5 2.2 citrate lyase ACP compare
BWI76_RS10815 +0.5 1.5 iron permease compare
BWI76_RS25920 +0.5 0.9 peptidylprolyl isomerase compare
BWI76_RS10535 +0.5 1.1 Asp/Glu/hydantoin racemase compare
BWI76_RS02930 +0.5 2.7 anaerobic ribonucleoside-triphosphate reductase activating protein compare
BWI76_RS22285 +0.5 2.4 transcriptional regulator compare
BWI76_RS16820 +0.5 2.0 iron ABC transporter compare
BWI76_RS23750 +0.5 2.2 arsenical efflux pump membrane protein ArsB compare
BWI76_RS01685 +0.5 2.8 methionine synthase compare
BWI76_RS10805 +0.5 1.9 hypothetical protein compare
BWI76_RS13415 +0.5 2.3 spermidine/putrescine ABC transporter permease compare
BWI76_RS13990 +0.5 2.4 allophanate hydrolase compare
BWI76_RS11835 +0.5 1.0 putative regulatory protein MarR compare
BWI76_RS05425 +0.5 2.1 EEP domain-containing protein compare
BWI76_RS03310 +0.5 0.9 AraC family transcriptional regulator compare
BWI76_RS12975 +0.5 2.5 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS08380 +0.5 0.5 endonuclease VIII compare
BWI76_RS15020 +0.5 1.8 2-oxobutyrate oxidase compare
BWI76_RS02635 +0.5 2.8 3-keto-L-gulonate-6-phosphate decarboxylase compare
BWI76_RS15185 +0.5 1.1 N-acetyltransferase compare
BWI76_RS11490 +0.5 1.8 MltA-interacting protein MipA compare
BWI76_RS18600 +0.5 2.4 HupC/HyaC/HydC family protein compare
BWI76_RS10560 +0.5 1.7 gamma-glutamyltransferase compare
BWI76_RS13685 +0.5 0.7 IclR family transcriptional regulator compare
BWI76_RS23335 +0.5 2.6 GNAT family acetyltransferase compare
BWI76_RS24770 +0.5 1.1 hypothetical protein compare
BWI76_RS02745 +0.5 0.8 hypothetical protein compare
BWI76_RS01540 +0.5 0.8 thiamine biosynthesis protein ThiS compare
BWI76_RS25905 +0.5 1.4 hypothetical protein compare
BWI76_RS22270 +0.5 1.8 nickel transporter compare
BWI76_RS25680 +0.5 2.6 16S rRNA m5C967 methyltransferase compare
BWI76_RS14225 +0.5 2.0 anti-ECF sigma factor ChrR compare
BWI76_RS04895 +0.5 0.9 hypothetical protein compare
BWI76_RS13785 +0.5 0.9 ABC transporter permease compare
BWI76_RS04165 +0.5 2.3 DNA repair protein RadA compare
BWI76_RS22850 +0.5 1.3 tRNA pseudouridine synthase TruC compare
BWI76_RS24380 +0.5 2.2 esterase YqiA compare
BWI76_RS17080 +0.5 2.4 hypothetical protein compare
BWI76_RS24825 +0.5 1.3 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS15015 +0.5 0.8 DUF2132 domain-containing protein compare
BWI76_RS08370 +0.5 1.1 membrane protein compare
BWI76_RS07545 +0.5 2.8 amidase compare
BWI76_RS13155 +0.5 1.7 hypothetical protein compare
BWI76_RS23015 +0.5 0.8 cobalt transporter ATP-binding subunit compare
BWI76_RS13125 +0.5 1.8 3-hydroxyacyl-CoA dehydrogenase compare


Specific Phenotypes

For 10 genes in this experiment

For nitrogen source Thymidine in Klebsiella michiganensis M5al

For nitrogen source Thymidine across organisms