Experiment set6IT067 for Klebsiella michiganensis M5al

Compare to:

Uridine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.3 -3.3 histidinol-phosphate transaminase compare
BWI76_RS20965 -8.9 -3.1 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS11855 -8.6 -4.9 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS18950 -8.3 -3.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00385 -8.2 -5.7 nitrogen assimilation regulatory protein compare
BWI76_RS21465 -8.0 -3.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS11850 -8.0 -7.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS11860 -7.9 -5.3 anthranilate synthase component I compare
BWI76_RS04470 -7.9 -5.5 carbamoyl phosphate synthase large subunit compare
BWI76_RS18925 -7.8 -3.3 histidinol dehydrogenase compare
BWI76_RS04465 -7.5 -3.7 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23365 -7.5 -2.8 LysR family transcriptional regulator compare
BWI76_RS22805 -7.4 -8.8 GTP diphosphokinase compare
BWI76_RS18935 -7.4 -6.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS22755 -7.3 -4.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS23220 -7.2 -6.1 amino-acid N-acetyltransferase compare
BWI76_RS18920 -7.2 -2.9 ATP phosphoribosyltransferase compare
BWI76_RS18940 -7.2 -3.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00785 -7.2 -4.8 cystathionine gamma-synthase compare
BWI76_RS05835 -7.1 -2.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS04160 -6.9 -5.8 phosphoserine phosphatase compare
BWI76_RS23920 -6.7 -4.2 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00390 -6.6 -5.0 two-component system sensor histidine kinase NtrB compare
BWI76_RS10775 -6.4 -6.1 pyrimidine utilization protein B conserved
BWI76_RS07070 -6.4 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00855 -6.3 -6.8 argininosuccinate lyase compare
BWI76_RS00835 -6.3 -12.9 phosphoenolpyruvate carboxylase compare
BWI76_RS25315 -6.2 -14.5 glutamate synthase large subunit compare
BWI76_RS25065 -6.2 -2.8 polyribonucleotide nucleotidyltransferase compare
BWI76_RS04645 -6.2 -6.3 3-dehydroquinase compare
BWI76_RS00990 -6.2 -7.0 ketol-acid reductoisomerase compare
BWI76_RS25115 -6.1 -6.6 argininosuccinate synthase compare
BWI76_RS01615 -6.1 -8.0 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00850 -6.0 -4.5 acetylglutamate kinase compare
BWI76_RS25320 -6.0 -6.4 glutamate synthase compare
BWI76_RS21070 -6.0 -2.1 outer membrane protein assembly factor BamB compare
BWI76_RS23360 -6.0 -2.4 diaminopimelate decarboxylase compare
BWI76_RS20350 -6.0 -4.9 amidophosphoribosyltransferase compare
BWI76_RS25645 -5.9 -8.0 shikimate dehydrogenase compare
BWI76_RS09755 -5.9 -6.1 phosphoserine transaminase compare
BWI76_RS05840 -5.8 -3.9 glutamate 5-kinase compare
BWI76_RS05015 -5.8 -2.4 transcriptional regulator compare
BWI76_RS10780 -5.6 -3.6 pyrimidine utilization protein A compare
BWI76_RS25920 -5.6 -2.0 peptidylprolyl isomerase compare
BWI76_RS04525 -5.6 -2.0 4-hydroxythreonine-4-phosphate dehydrogenase PdxA compare
BWI76_RS00845 -5.5 -7.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS08405 -5.5 -2.4 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS08385 -5.4 -2.7 citrate (Si)-synthase compare
BWI76_RS10765 -5.2 -3.5 pyrimidine utilization protein D compare
BWI76_RS08180 -5.2 -7.5 asparagine synthase B compare
BWI76_RS17720 -5.2 -1.1 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS10755 -5.2 -1.1 pyrimidine utilization flavin reductase protein F compare
BWI76_RS13560 -5.1 -1.0 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS11430 -5.1 -1.0 lipoprotein compare
BWI76_RS04305 -5.1 -1.0 molecular chaperone DnaJ compare
BWI76_RS02530 -5.0 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS12790 -5.0 -1.0 lactate dehydrogenase compare
BWI76_RS02725 -5.0 -1.0 HxlR family transcriptional regulator compare
BWI76_RS00345 -5.0 -3.0 protein disulfide oxidoreductase DsbA compare
BWI76_RS25600 -5.0 -1.0 tRNA-Thr compare
BWI76_RS09615 -5.0 -2.0 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS04245 -4.9 -10.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11440 -4.9 -1.0 hypothetical protein compare
BWI76_RS07985 -4.9 -1.0 fluoride ion transporter CrcB compare
BWI76_RS00400 -4.9 -1.7 glutamine synthetase compare
BWI76_RS14915 -4.9 -2.4 hypothetical protein compare
BWI76_RS26620 -4.8 -1.0 Fe-S biogenesis protein NfuA compare
BWI76_RS15845 -4.7 -1.0 hypothetical protein compare
BWI76_RS01630 -4.7 -1.0 16S ribosomal RNA compare
BWI76_RS00980 -4.7 -7.3 PLP-dependent threonine dehydratase compare
BWI76_RS07595 -4.7 -1.9 putative oxidoreductase compare
BWI76_RS12090 -4.6 -2.3 HNH endonuclease compare
BWI76_RS08765 -4.5 -2.7 8-amino-7-oxononanoate synthase compare
BWI76_RS04250 -4.5 -4.3 homoserine kinase compare
BWI76_RS11845 -4.5 -1.7 tryptophan synthase subunit beta compare
BWI76_RS00805 -4.5 -3.1 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS14615 -4.5 -1.3 hypothetical protein compare
BWI76_RS01655 -4.5 -3.1 homoserine O-succinyltransferase compare
BWI76_RS04670 -4.4 -5.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS08110 -4.3 -2.2 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS24285 -4.3 -4.2 cystathionine beta-lyase compare
BWI76_RS20355 -4.2 -2.3 colicin V production protein compare
BWI76_RS05200 -4.2 -2.3 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS20895 -4.2 -3.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS26085 -4.2 -2.0 3-dehydroquinate synthase compare
BWI76_RS00140 -4.1 -0.8 phosphate transport system regulator PhoU compare
BWI76_RS07065 -4.1 -3.9 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS22760 -4.0 -5.9 sulfite reductase subunit beta compare
BWI76_RS10835 -4.0 -1.2 hypothetical protein compare
BWI76_RS00975 -4.0 -5.7 dihydroxy-acid dehydratase compare
BWI76_RS25000 -3.9 -1.1 malonate decarboxylase acyl carrier protein compare
BWI76_RS09660 -3.9 -1.8 DNA translocase FtsK compare
BWI76_RS11840 -3.9 -3.9 tryptophan synthase subunit alpha compare
BWI76_RS04255 -3.9 -6.1 threonine synthase compare
BWI76_RS25070 -3.8 -1.1 hypothetical protein compare
BWI76_RS23230 -3.8 -4.5 exodeoxyribonuclease V subunit beta compare
BWI76_RS10760 -3.8 -2.7 nitroreductase family protein compare
BWI76_RS10770 -3.8 -1.6 pyrimidine utilization protein C compare
BWI76_RS04675 -3.8 -2.9 3-isopropylmalate dehydrogenase compare
BWI76_RS11980 -3.7 -1.1 DeoR family transcriptional regulator compare
BWI76_RS22765 -3.7 -5.2 sulfite reductase subunit alpha compare
BWI76_RS07185 -3.7 -1.6 hypothetical protein compare
BWI76_RS21475 -3.7 -3.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS23520 -3.6 -1.3 hypothetical protein compare
BWI76_RS04240 -3.6 -1.8 thr operon leader peptide compare
BWI76_RS26570 -3.6 -3.5 anion permease compare
BWI76_RS11435 -3.6 -1.7 hypothetical protein compare
BWI76_RS09760 -3.5 -2.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS09645 -3.5 -1.0 thioredoxin-disulfide reductase compare
BWI76_RS17045 -3.5 -1.2 hypothetical protein compare
BWI76_RS26440 -3.4 -1.2 hypothetical protein compare
BWI76_RS23240 -3.4 -3.8 exonuclease V subunit gamma compare
BWI76_RS19495 -3.4 -1.0 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS07785 -3.3 -1.4 transcriptional regulator compare
BWI76_RS03010 -3.3 -4.5 ornithine carbamoyltransferase compare
BWI76_RS21265 -3.3 -5.8 phosphoribosylformylglycinamidine synthase compare
BWI76_RS03045 -3.3 -0.9 hypothetical protein compare
BWI76_RS15035 -3.3 -0.8 metal ABC transporter permease compare
BWI76_RS04665 -3.2 -10.6 3-isopropylmalate dehydratase small subunit compare
BWI76_RS01295 -3.2 -5.5 Uridine phosphorylase (EC 2.4.2.3) (from data) compare
BWI76_RS01210 -3.1 -1.8 tyrosine recombinase XerC compare
BWI76_RS17300 -3.1 -0.9 tRNA-Tyr compare
BWI76_RS01195 -3.1 -1.5 membrane protein compare
BWI76_RS02735 -3.1 -4.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS19705 -3.1 -3.6 kinase compare
BWI76_RS04680 -3.0 -6.4 2-isopropylmalate synthase compare
BWI76_RS18360 -3.0 -1.8 aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase family protein compare
BWI76_RS22690 -3.0 -1.9 adenylyl-sulfate kinase compare
BWI76_RS23480 -3.0 -10.0 EAL domain-containing protein compare
BWI76_RS00180 -3.0 -1.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS04685 -3.0 -5.3 putative leucine operon leader peptide compare
BWI76_RS20435 -2.9 -0.8 chorismate synthase compare
BWI76_RS17195 -2.9 -1.8 hypothetical protein compare
BWI76_RS15835 -2.8 -1.8 hypothetical protein compare
BWI76_RS01610 -2.8 -3.3 phosphoribosylamine--glycine ligase compare
BWI76_RS08535 -2.8 -2.1 translocation protein TolB compare
BWI76_RS27875 -2.7 -0.8 membrane protein compare
BWI76_RS20050 -2.7 -1.2 hypothetical protein compare
BWI76_RS08375 -2.7 -1.5 pyroglutamyl-peptidase I compare
BWI76_RS07790 -2.7 -1.5 plasmid stabilization protein compare
BWI76_RS14870 -2.7 -1.9 hypothetical protein compare
BWI76_RS18770 -2.5 -0.9 DNA gyrase inhibitor compare
BWI76_RS26410 -2.5 -1.4 membrane protein compare
BWI76_RS21480 -2.5 -4.1 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS23320 -2.4 -1.0 hypothetical protein compare
BWI76_RS06535 -2.4 -2.5 endopeptidase La compare
BWI76_RS09970 -2.4 -3.0 porin OmpA compare
BWI76_RS16210 -2.4 -1.1 hypothetical protein compare
BWI76_RS14805 -2.3 -1.3 hypothetical protein compare
BWI76_RS04140 -2.3 -3.6 phosphopentomutase compare
BWI76_RS20795 -2.3 -0.9 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS18955 -2.3 -4.3 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21340 -2.3 -1.1 SoxR reducing system protein RseC compare
BWI76_RS07640 -2.3 -1.2 short chain dehydrogenase compare
BWI76_RS26685 -2.2 -3.9 glutathione-disulfide reductase compare
BWI76_RS09655 -2.2 -1.9 leucine-responsive regulatory protein compare
BWI76_RS07995 -2.2 -2.4 twin-arginine translocase subunit TatA compare
BWI76_RS08605 -2.2 -1.7 phosphoglyceromutase compare
BWI76_RS15620 -2.2 -1.5 hypothetical protein compare
BWI76_RS15825 -2.2 -1.1 hypothetical protein compare
BWI76_RS11780 -2.2 -1.7 2-deoxyglucose-6-phosphatase compare
BWI76_RS24110 -2.2 -1.6 YggU family protein compare
BWI76_RS18430 -2.2 -1.5 hypothetical protein compare
BWI76_RS04270 -2.1 -2.1 transaldolase compare
BWI76_RS12750 -2.1 -2.9 hypothetical protein compare
BWI76_RS16470 -2.1 -1.0 transcriptional repressor NemR compare
BWI76_RS22645 -2.1 -2.5 RNA polymerase sigma factor RpoS compare
BWI76_RS21980 -2.1 -2.5 hypothetical protein compare
BWI76_RS21580 -2.1 -1.4 SsrA-binding protein compare
BWI76_RS14305 -2.1 -2.4 metallophosphoesterase compare
BWI76_RS19405 -2.1 -2.0 LysR family transcriptional regulator compare
BWI76_RS06530 -2.1 -2.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS12465 -2.0 -0.8 phage shock protein D compare
BWI76_RS00355 -2.0 -1.8 DNA polymerase I compare
BWI76_RS05810 -2.0 -0.8 hypothetical protein compare
BWI76_RS16645 -2.0 -1.6 DeoR family transcriptional regulator compare
BWI76_RS05120 -2.0 -4.0 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS09145 -2.0 -2.1 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS13545 -2.0 -1.0 N-acetyltransferase compare
BWI76_RS20490 -2.0 -2.3 hypothetical protein compare
BWI76_RS00565 -1.9 -1.7 branched-chain amino acid transport compare
BWI76_RS14320 -1.9 -1.4 hypothetical protein compare
BWI76_RS25960 -1.9 -3.0 NUDIX hydrolase compare
BWI76_RS18565 -1.8 -1.6 pemk protein compare
BWI76_RS13820 -1.8 -1.2 hypothetical protein compare
BWI76_RS23340 -1.8 -1.5 transcriptional regulator compare
BWI76_RS23030 -1.8 -1.2 cobalamin biosynthesis protein CbiM compare
BWI76_RS11040 -1.8 -2.5 ribonuclease E compare
BWI76_RS26015 -1.8 -1.3 DUF2559 domain-containing protein compare
BWI76_RS10500 -1.8 -1.5 flavoprotein monooxygenase compare
BWI76_RS12495 -1.8 -1.2 2-Cys peroxiredoxin compare
BWI76_RS08210 -1.8 -1.3 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS25280 -1.7 -1.1 RNase adaptor protein RapZ compare
BWI76_RS26395 -1.7 -2.4 cell division protein FtsE compare
BWI76_RS14245 -1.7 -1.7 carboxymuconolactone decarboxylase family protein compare
BWI76_RS11920 -1.7 -2.3 hypothetical protein compare
BWI76_RS12515 -1.7 -1.4 protease compare
BWI76_RS07740 -1.7 -1.0 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS09025 -1.7 -1.4 GntR family transcriptional regulator compare
BWI76_RS16075 -1.7 -0.9 oxidoreductase compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source Uridine in Klebsiella michiganensis M5al

For nitrogen source Uridine across organisms