Experiment set6IT065 for Klebsiella michiganensis M5al

Compare to:

Parabanic Acid nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS11965 -8.6 -5.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18950 -8.6 -5.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00990 -7.6 -7.4 ketol-acid reductoisomerase compare
BWI76_RS18920 -7.5 -5.1 ATP phosphoribosyltransferase compare
BWI76_RS18940 -7.5 -5.1 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS20895 -7.4 -5.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04670 -7.2 -8.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS25115 -7.2 -8.6 argininosuccinate synthase compare
BWI76_RS04160 -7.1 -8.0 phosphoserine phosphatase compare
BWI76_RS18935 -7.0 -6.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS05840 -6.9 -4.8 glutamate 5-kinase compare
BWI76_RS04255 -6.8 -9.4 threonine synthase compare
BWI76_RS04470 -6.8 -11.4 carbamoyl phosphate synthase large subunit compare
BWI76_RS04675 -6.8 -8.0 3-isopropylmalate dehydrogenase compare
BWI76_RS00850 -6.8 -10.6 acetylglutamate kinase compare
BWI76_RS04250 -6.8 -9.3 homoserine kinase compare
BWI76_RS08385 -6.7 -3.6 citrate (Si)-synthase compare
BWI76_RS01615 -6.7 -10.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS21475 -6.6 -6.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS20350 -6.6 -5.7 amidophosphoribosyltransferase compare
BWI76_RS00805 -6.6 -5.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS18930 -6.5 -3.7 histidinol-phosphate transaminase compare
BWI76_RS25320 -6.4 -10.0 glutamate synthase compare
BWI76_RS21265 -6.4 -12.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18925 -6.4 -8.1 histidinol dehydrogenase compare
BWI76_RS02995 -6.3 -9.4 aspartate carbamoyltransferase compare
BWI76_RS20355 -6.3 -4.0 colicin V production protein compare
BWI76_RS04245 -6.3 -15.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04685 -6.2 -9.5 putative leucine operon leader peptide compare
BWI76_RS23360 -6.2 -4.1 diaminopimelate decarboxylase compare
BWI76_RS04645 -6.2 -7.5 3-dehydroquinase compare
BWI76_RS18955 -6.2 -6.5 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00980 -6.1 -12.5 PLP-dependent threonine dehydratase compare
BWI76_RS00855 -6.1 -11.6 argininosuccinate lyase compare
BWI76_RS23220 -6.0 -8.7 amino-acid N-acetyltransferase compare
BWI76_RS04665 -6.0 -22.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS22760 -6.0 -11.4 sulfite reductase subunit beta compare
BWI76_RS09755 -5.9 -8.4 phosphoserine transaminase compare
BWI76_RS04465 -5.8 -6.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS00835 -5.8 -16.4 phosphoenolpyruvate carboxylase compare
BWI76_RS05835 -5.8 -4.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS23920 -5.7 -6.3 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS22755 -5.7 -7.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11860 -5.7 -6.7 anthranilate synthase component I compare
BWI76_RS23365 -5.6 -7.3 LysR family transcriptional regulator compare
BWI76_RS00785 -5.4 -8.3 cystathionine gamma-synthase compare
BWI76_RS07070 -5.4 -6.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00385 -5.4 -10.0 nitrogen assimilation regulatory protein compare
BWI76_RS00390 -5.4 -5.4 two-component system sensor histidine kinase NtrB compare
BWI76_RS20965 -5.3 -5.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00845 -5.3 -10.6 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS27385 -5.3 -7.5 orotate phosphoribosyltransferase compare
BWI76_RS03010 -5.2 -6.8 ornithine carbamoyltransferase compare
BWI76_RS22765 -5.2 -16.8 sulfite reductase subunit alpha compare
BWI76_RS01610 -5.2 -8.4 phosphoribosylamine--glycine ligase compare
BWI76_RS25315 -5.2 -10.4 glutamate synthase large subunit compare
BWI76_RS00400 -5.1 -3.0 glutamine synthetase compare
BWI76_RS04680 -5.0 -12.5 2-isopropylmalate synthase compare
BWI76_RS24285 -4.9 -8.7 cystathionine beta-lyase compare
BWI76_RS21465 -4.9 -4.3 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS01655 -4.8 -6.8 homoserine O-succinyltransferase compare
BWI76_RS09910 -4.8 -14.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS25645 -4.8 -10.2 shikimate dehydrogenase compare
BWI76_RS04510 -4.7 -3.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS11840 -4.7 -2.2 tryptophan synthase subunit alpha compare
BWI76_RS22690 -4.7 -5.5 adenylyl-sulfate kinase compare
BWI76_RS26455 -4.6 -5.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS00975 -4.6 -7.2 dihydroxy-acid dehydratase compare
BWI76_RS09760 -4.6 -3.4 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS11850 -4.5 -5.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS26085 -4.4 -3.4 3-dehydroquinate synthase compare
BWI76_RS23240 -4.4 -4.2 exonuclease V subunit gamma compare
BWI76_RS02735 -4.4 -6.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS02530 -4.3 -4.0 tRNA dimethylallyltransferase compare
BWI76_RS00985 -4.3 -7.7 transcriptional regulator IlvY compare
BWI76_RS09660 -4.3 -2.9 DNA translocase FtsK compare
BWI76_RS07065 -4.2 -5.3 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04240 -4.2 -2.5 thr operon leader peptide compare
BWI76_RS15825 -4.1 -2.5 hypothetical protein compare
BWI76_RS21140 -4.1 -3.9 molecular chaperone HscA compare
BWI76_RS10990 -4.1 -4.7 dihydroorotase compare
BWI76_RS15975 -4.0 -2.0 hypothetical protein compare
BWI76_RS11845 -4.0 -3.8 tryptophan synthase subunit beta compare
BWI76_RS23230 -4.0 -4.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS05200 -3.9 -3.8 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS27390 -3.9 -4.4 ribonuclease PH compare
BWI76_RS26000 -3.8 -10.2 aspartate aminotransferase family protein compare
BWI76_RS22805 -3.8 -10.4 GTP diphosphokinase compare
BWI76_RS11855 -3.8 -5.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS23265 -3.6 -4.0 hypothetical protein compare
BWI76_RS00965 -3.6 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS09970 -3.5 -6.3 porin OmpA compare
BWI76_RS05015 -3.5 -3.4 transcriptional regulator compare
BWI76_RS26460 -3.4 -5.2 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS24520 -3.3 -7.3 urease accessory protein UreF conserved
BWI76_RS16965 -3.1 -6.1 murein lipoprotein compare
BWI76_RS26055 -3.1 -8.1 siroheme synthase compare
BWI76_RS16235 -3.0 -3.0 membrane protein compare
BWI76_RS20435 -3.0 -1.4 chorismate synthase compare
BWI76_RS24495 -2.9 -5.6 urease accessory protein conserved
BWI76_RS20640 -2.8 -6.1 cysteine synthase A compare
BWI76_RS24505 -2.6 -4.4 urease subunit beta compare
BWI76_RS01200 -2.6 -2.5 diaminopimelate epimerase compare
BWI76_RS02410 -2.6 -2.5 EF-P beta-lysylation protein EpmB compare
BWI76_RS01210 -2.5 -2.6 tyrosine recombinase XerC compare
BWI76_RS24525 -2.5 -3.8 urease accessory protein UreG conserved
BWI76_RS20155 -2.4 -3.1 NADH-quinone oxidoreductase subunit I compare
BWI76_RS22695 -2.4 -3.7 sulfate adenylyltransferase compare
BWI76_RS12145 -2.4 -2.2 hypothetical protein compare
BWI76_RS22700 -2.4 -6.4 sulfate adenylyltransferase subunit 2 compare
BWI76_RS24515 -2.3 -6.7 urease accessory protein UreE conserved
BWI76_RS24465 -2.3 -8.4 adenylate cyclase compare
BWI76_RS24510 -2.2 -6.4 urease subunit alpha conserved
BWI76_RS24500 -2.2 -3.0 urease subunit gamma compare
BWI76_RS09645 -2.2 -1.7 thioredoxin-disulfide reductase compare
BWI76_RS08520 -2.1 -2.7 colicin transporter TolQ compare
BWI76_RS09655 -2.1 -3.4 leucine-responsive regulatory protein compare
BWI76_RS15835 -2.0 -1.2 hypothetical protein compare
BWI76_RS00960 -2.0 -4.6 acetolactate synthase 2 catalytic subunit compare
BWI76_RS13755 -1.9 -2.3 hypothetical protein compare
BWI76_RS04305 -1.8 -1.5 molecular chaperone DnaJ compare
BWI76_RS12090 -1.8 -2.1 HNH endonuclease compare
BWI76_RS25425 -1.8 -2.3 arginine repressor compare
BWI76_RS17720 -1.7 -1.5 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS23895 -1.7 -2.1 Xaa-Pro aminopeptidase compare
BWI76_RS24925 -1.7 -1.9 DnaA initiator-associating protein DiaA compare
BWI76_RS21070 -1.7 -2.8 outer membrane protein assembly factor BamB compare
BWI76_RS17975 -1.7 -3.2 tail-specific protease compare
BWI76_RS26570 -1.7 -2.8 anion permease compare
BWI76_RS15990 -1.7 -5.5 serine protease compare
BWI76_RS00345 -1.6 -3.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS06530 -1.6 -4.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS15115 -1.6 -5.3 MFS transporter compare
BWI76_RS09650 -1.5 -3.4 hypothetical protein compare
BWI76_RS06525 -1.5 -5.3 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS17980 -1.5 -4.0 RNA chaperone ProQ compare
BWI76_RS25335 -1.5 -3.2 stringent starvation protein A compare
BWI76_RS26395 -1.5 -4.8 cell division protein FtsE compare
BWI76_RS09030 -1.5 -6.1 transpeptidase compare
BWI76_RS15850 -1.5 -2.3 DUF1317 domain-containing protein compare
BWI76_RS20440 -1.5 -1.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS21480 -1.4 -3.3 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS21685 -1.4 -1.5 hypothetical protein compare
BWI76_RS26405 -1.4 -1.7 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS26075 -1.4 -3.1 DNA adenine methylase compare
BWI76_RS23480 -1.4 -7.9 EAL domain-containing protein compare
BWI76_RS20650 -1.3 -2.0 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS26775 -1.3 -3.5 endo-1,4-D-glucanase compare
BWI76_RS01870 -1.3 -4.2 diacylglycerol kinase compare
BWI76_RS20695 -1.3 -3.5 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS08180 -1.2 -5.6 asparagine synthase B compare
BWI76_RS08720 -1.2 -1.5 imidazolonepropionase compare
BWI76_RS15110 -1.2 -7.0 putative excinuclease ABC subunit A compare
BWI76_RS14005 -1.2 -1.9 TetR family transcriptional regulator compare
BWI76_RS22950 -1.2 -2.7 membrane protein compare
BWI76_RS06765 -1.2 -1.8 transcriptional regulator compare
BWI76_RS11105 -1.2 -2.4 aminodeoxychorismate lyase compare
BWI76_RS01095 -1.2 -1.7 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS23915 -1.2 -2.0 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS20900 -1.2 -1.3 outer membrane protein assembly factor BamC compare
BWI76_RS02990 -1.2 -3.1 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS25280 -1.1 -1.6 RNase adaptor protein RapZ compare
BWI76_RS13560 -1.1 -1.2 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS22705 -1.1 -3.3 siroheme synthase compare
BWI76_RS18000 -1.1 -2.4 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF compare
BWI76_RS20970 -1.1 -1.3 phosphoribosylglycinamide formyltransferase compare
BWI76_RS12390 -1.1 -2.2 antibiotic biosynthesis monooxygenase compare
BWI76_RS08525 -1.1 -1.9 colicin transporter compare
BWI76_RS14050 -1.1 -2.1 AP endonuclease, family 2 compare
BWI76_RS12895 -1.1 -1.9 hypothetical protein compare
BWI76_RS02855 -1.1 -2.7 cytochrome B562 compare
BWI76_RS07115 -1.1 -4.0 hypothetical protein compare
BWI76_RS09615 -1.0 -1.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS01775 -1.0 -1.0 hypothetical protein compare
BWI76_RS15840 -1.0 -2.7 prophage protein compare
BWI76_RS25065 -1.0 -3.0 polyribonucleotide nucleotidyltransferase compare
BWI76_RS09145 -1.0 -2.1 serine-type D-Ala-D-Ala carboxypeptidase compare
BWI76_RS18165 -1.0 -1.4 NUDIX pyrophosphatase compare
BWI76_RS00970 -1.0 -2.0 branched chain amino acid aminotransferase compare
BWI76_RS15640 -1.0 -5.1 hypothetical protein compare
BWI76_RS16935 -1.0 -1.3 shikimate dehydrogenase compare
BWI76_RS04715 -1.0 -1.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS06485 -1.0 -2.1 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS15830 -1.0 -1.8 hypothetical protein compare
BWI76_RS12790 -1.0 -1.0 lactate dehydrogenase compare
BWI76_RS06475 -1.0 -1.3 protoheme IX farnesyltransferase compare
BWI76_RS12885 -1.0 -2.0 hypothetical protein compare
BWI76_RS20490 -1.0 -2.0 hypothetical protein compare
BWI76_RS00760 -1.0 -3.1 cell division protein FtsN compare
BWI76_RS20845 -0.9 -2.1 GDP-mannose pyrophosphatase NudK compare
BWI76_RS09315 -0.9 -1.8 hypothetical protein compare
BWI76_RS21375 -0.9 -1.4 autonomous glycyl radical cofactor GrcA compare
BWI76_RS25505 -0.9 -3.4 RNase E specificity factor CsrD compare
BWI76_RS06535 -0.9 -2.2 endopeptidase La compare
BWI76_RS09255 -0.9 -1.7 hypothetical protein compare
BWI76_RS15735 -0.9 -0.9 hypothetical protein compare
BWI76_RS10930 -0.9 -5.6 glucan biosynthesis protein G compare
BWI76_RS16425 -0.9 -3.3 hypothetical protein compare
BWI76_RS11430 -0.9 -1.0 lipoprotein compare
BWI76_RS13730 -0.9 -1.6 hypothetical protein compare


Specific Phenotypes

For 5 genes in this experiment

For nitrogen source Parabanic Acid in Klebsiella michiganensis M5al

For nitrogen source Parabanic Acid across organisms