Experiment set6IT060 for Klebsiella michiganensis M5al

Compare to:

Gly-DL-Asp nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20965 -9.0 -5.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS00805 -8.7 -6.0 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01210 -7.9 -5.3 tyrosine recombinase XerC compare
BWI76_RS18930 -7.5 -5.9 histidinol-phosphate transaminase compare
BWI76_RS24285 -7.4 -7.2 cystathionine beta-lyase compare
BWI76_RS18920 -7.3 -5.0 ATP phosphoribosyltransferase compare
BWI76_RS18940 -7.3 -5.0 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS05835 -7.1 -4.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS18925 -7.1 -6.9 histidinol dehydrogenase compare
BWI76_RS20355 -6.9 -4.4 colicin V production protein compare
BWI76_RS04250 -6.8 -8.1 homoserine kinase compare
BWI76_RS04470 -6.7 -11.2 carbamoyl phosphate synthase large subunit compare
BWI76_RS25115 -6.6 -7.9 argininosuccinate synthase compare
BWI76_RS08385 -6.5 -3.8 citrate (Si)-synthase compare
BWI76_RS07070 -6.4 -6.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS20895 -6.4 -5.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS20350 -6.3 -6.7 amidophosphoribosyltransferase compare
BWI76_RS05840 -6.2 -6.0 glutamate 5-kinase compare
BWI76_RS18935 -6.1 -5.6 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23220 -6.1 -8.3 amino-acid N-acetyltransferase compare
BWI76_RS27385 -6.0 -7.2 orotate phosphoribosyltransferase compare
BWI76_RS04465 -6.0 -7.1 carbamoyl-phosphate synthase small subunit compare
BWI76_RS00850 -5.9 -12.2 acetylglutamate kinase compare
BWI76_RS00990 -5.6 -10.1 ketol-acid reductoisomerase compare
BWI76_RS00785 -5.5 -8.4 cystathionine gamma-synthase compare
BWI76_RS04255 -5.5 -9.9 threonine synthase compare
BWI76_RS01655 -5.4 -8.5 homoserine O-succinyltransferase compare
BWI76_RS02995 -5.4 -10.0 aspartate carbamoyltransferase compare
BWI76_RS00855 -5.3 -8.1 argininosuccinate lyase compare
BWI76_RS10990 -5.3 -3.0 dihydroorotase compare
BWI76_RS04645 -5.3 -8.0 3-dehydroquinase compare
BWI76_RS04245 -5.2 -14.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS01615 -5.1 -9.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS00845 -5.1 -9.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS21265 -5.1 -10.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18955 -5.0 -7.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS22755 -5.0 -8.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11860 -5.0 -8.7 anthranilate synthase component I compare
BWI76_RS11855 -4.9 -6.5 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS11850 -4.9 -6.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS03010 -4.8 -7.8 ornithine carbamoyltransferase compare
BWI76_RS09910 -4.8 -16.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS18950 -4.8 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS11840 -4.8 -6.0 tryptophan synthase subunit alpha compare
BWI76_RS23360 -4.7 -5.6 diaminopimelate decarboxylase compare
BWI76_RS00980 -4.7 -9.9 PLP-dependent threonine dehydratase compare
BWI76_RS01610 -4.6 -5.4 phosphoribosylamine--glycine ligase compare
BWI76_RS09760 -4.5 -7.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00975 -4.4 -7.3 dihydroxy-acid dehydratase compare
BWI76_RS23230 -4.4 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS04675 -4.2 -7.6 3-isopropylmalate dehydrogenase compare
BWI76_RS09660 -4.1 -2.8 DNA translocase FtsK compare
BWI76_RS21475 -4.0 -5.5 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS11845 -4.0 -3.6 tryptophan synthase subunit beta compare
BWI76_RS11965 -4.0 -3.1 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23365 -3.9 -9.1 LysR family transcriptional regulator compare
BWI76_RS04665 -3.9 -17.8 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04670 -3.8 -8.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04680 -3.7 -10.9 2-isopropylmalate synthase compare
BWI76_RS23240 -3.7 -4.3 exonuclease V subunit gamma compare
BWI76_RS04685 -3.6 -10.3 putative leucine operon leader peptide compare
BWI76_RS21465 -3.6 -3.5 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04240 -3.6 -3.1 thr operon leader peptide compare
BWI76_RS22765 -3.5 -12.3 sulfite reductase subunit alpha compare
BWI76_RS25645 -3.5 -10.1 shikimate dehydrogenase compare
BWI76_RS26085 -3.3 -3.3 3-dehydroquinate synthase compare
BWI76_RS07065 -3.2 -7.4 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS26455 -3.0 -6.0 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS22760 -3.0 -6.0 sulfite reductase subunit beta compare
BWI76_RS20435 -2.9 -1.5 chorismate synthase compare
BWI76_RS05200 -2.9 -3.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS25320 -2.9 -6.9 glutamate synthase compare
BWI76_RS23875 -2.8 -4.5 glycine cleavage system protein H compare
BWI76_RS23870 -2.8 -9.7 Glycine dehydrogenase (aminomethyl-transferring) (EC 1.4.4.2) (from data) conserved
BWI76_RS09755 -2.7 -4.1 phosphoserine transaminase compare
BWI76_RS22690 -2.7 -3.7 adenylyl-sulfate kinase compare
BWI76_RS00965 -2.7 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS25315 -2.7 -12.6 glutamate synthase large subunit compare
BWI76_RS26875 -2.7 -2.1 dipeptide ABC transporter permease DppC compare
BWI76_RS23880 -2.5 -6.7 Aminomethyltransferase (EC 2.1.2.10) (from data) conserved
BWI76_RS22805 -2.5 -10.4 GTP diphosphokinase compare
BWI76_RS00400 -2.5 -1.8 glutamine synthetase compare
BWI76_RS08180 -2.4 -9.2 asparagine synthase B compare
BWI76_RS05015 -2.4 -2.3 transcriptional regulator compare
BWI76_RS09970 -2.4 -3.1 porin OmpA compare
BWI76_RS00390 -2.3 -5.0 two-component system sensor histidine kinase NtrB compare
BWI76_RS02530 -2.3 -2.8 tRNA dimethylallyltransferase compare
BWI76_RS22695 -2.3 -4.6 sulfate adenylyltransferase compare
BWI76_RS04305 -2.2 -1.7 molecular chaperone DnaJ compare
BWI76_RS16965 -2.2 -4.6 murein lipoprotein compare
BWI76_RS23480 -2.2 -10.6 EAL domain-containing protein compare
BWI76_RS27390 -2.2 -2.7 ribonuclease PH compare
BWI76_RS00385 -2.0 -7.2 nitrogen assimilation regulatory protein compare
BWI76_RS15835 -2.0 -1.4 hypothetical protein compare
BWI76_RS00985 -2.0 -5.7 transcriptional regulator IlvY compare
BWI76_RS06540 -2.0 -4.2 DNA-binding protein HU-beta compare
BWI76_RS26880 -2.0 -7.8 dipeptide ABC transporter permease DppB conserved
BWI76_RS09645 -1.9 -1.6 thioredoxin-disulfide reductase compare
BWI76_RS18630 -1.9 -5.3 nitrogen assimilation transcriptional regulator conserved
BWI76_RS02735 -1.9 -4.0 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS26865 -1.9 -4.8 dipeptide ABC transporter ATP-binding protein compare
BWI76_RS26440 -1.8 -2.0 hypothetical protein compare
BWI76_RS26460 -1.8 -5.5 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS04530 -1.7 -2.6 peptidylprolyl isomerase SurA compare
BWI76_RS17980 -1.7 -3.2 RNA chaperone ProQ compare
BWI76_RS04510 -1.7 -2.6 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS26885 -1.7 -9.6 ABC transporter substrate-binding protein conserved
BWI76_RS27430 -1.7 -1.4 (p)ppGpp synthetase compare
BWI76_RS22955 -1.6 -3.2 transcriptional regulator GcvA compare
BWI76_RS26870 -1.6 -3.0 dipeptide ABC transporter ATP-binding protein compare
BWI76_RS01800 -1.6 -3.4 glucose-6-phosphate isomerase compare
BWI76_RS00960 -1.6 -4.2 acetolactate synthase 2 catalytic subunit compare
BWI76_RS13820 -1.6 -2.0 hypothetical protein compare
BWI76_RS23915 -1.6 -2.8 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS24100 -1.5 -4.0 YggS family pyridoxal phosphate enzyme compare
BWI76_RS09030 -1.5 -5.0 transpeptidase compare
BWI76_RS22700 -1.5 -6.2 sulfate adenylyltransferase subunit 2 compare
BWI76_RS21235 -1.4 -1.4 hypothetical protein compare
BWI76_RS21480 -1.4 -4.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS16485 -1.4 -1.5 ribonuclease T compare
BWI76_RS11255 -1.4 -1.4 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS21450 -1.3 -2.9 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS03665 -1.3 -1.6 ABC transporter ATP-binding protein compare
BWI76_RS17530 -1.3 -2.4 hypothetical protein compare
BWI76_RS20970 -1.3 -1.5 phosphoribosylglycinamide formyltransferase compare
BWI76_RS13755 -1.3 -1.8 hypothetical protein compare
BWI76_RS26890 -1.3 -0.9 hypothetical protein compare
BWI76_RS00140 -1.2 -0.9 phosphate transport system regulator PhoU compare
BWI76_RS12470 -1.2 -1.7 thiosulfate sulfurtransferase PspE compare
BWI76_RS27440 -1.2 -3.2 DNA helicase RecG compare
BWI76_RS00345 -1.2 -2.4 protein disulfide oxidoreductase DsbA compare
BWI76_RS18755 -1.2 -1.3 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS05880 -1.2 -2.2 AraC-type DNA-binding domain-containing protein compare
BWI76_RS23020 -1.2 -2.5 cobalamin biosynthesis protein CbiQ compare
BWI76_RS26055 -1.2 -5.3 siroheme synthase compare
BWI76_RS26670 -1.2 -6.1 two-component sensor histidine kinase compare
BWI76_RS27950 -1.2 -3.9 transcriptional regulator compare
BWI76_RS06190 -1.2 -1.5 hypothetical protein compare
BWI76_RS26665 -1.2 -3.3 DNA-binding response regulator compare
BWI76_RS08380 -1.1 -1.4 endonuclease VIII compare
BWI76_RS23265 -1.1 -2.4 hypothetical protein compare
BWI76_RS15115 -1.1 -4.6 MFS transporter compare
BWI76_RS19010 -1.1 -2.9 polysaccharide pyruvyl transferase yvff compare
BWI76_RS12090 -1.1 -1.0 HNH endonuclease compare
BWI76_RS01995 -1.1 -1.3 AraC family transcriptional regulator compare
BWI76_RS08525 -1.1 -1.9 colicin transporter compare
BWI76_RS11015 -1.1 -1.2 hypothetical protein compare
BWI76_RS14650 -1.1 -2.3 helix-turn-helix transcriptional regulator compare
BWI76_RS09255 -1.1 -1.8 hypothetical protein compare
BWI76_RS11040 -1.1 -2.1 ribonuclease E compare
BWI76_RS15990 -1.1 -3.4 serine protease compare
BWI76_RS01220 -1.1 -3.7 DNA-dependent helicase II compare
BWI76_RS15840 -1.1 -2.2 prophage protein compare
BWI76_RS21565 -1.1 -1.2 outer membrane protein assembly factor BamE compare
BWI76_RS15825 -1.0 -0.9 hypothetical protein compare
BWI76_RS02410 -1.0 -1.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS25920 -1.0 -1.7 peptidylprolyl isomerase compare
BWI76_RS21375 -1.0 -1.4 autonomous glycyl radical cofactor GrcA compare
BWI76_RS16240 -1.0 -1.8 anti-adapter protein IraM compare
BWI76_RS25600 -1.0 -1.1 tRNA-Thr compare
BWI76_RS13560 -1.0 -1.1 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS17200 -1.0 -1.5 hypothetical protein compare
BWI76_RS26620 -1.0 -1.0 Fe-S biogenesis protein NfuA compare
BWI76_RS20995 -1.0 -2.6 RNA degradosome polyphosphate kinase compare
BWI76_RS25480 -1.0 -2.1 ribonuclease E/G compare
BWI76_RS00075 -1.0 -2.5 N-acetylmannosamine-6-phosphate 2-epimerase compare
BWI76_RS19495 -1.0 -1.0 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS20050 -1.0 -1.4 hypothetical protein compare
BWI76_RS21070 -1.0 -2.0 outer membrane protein assembly factor BamB compare
BWI76_RS08535 -1.0 -2.0 translocation protein TolB compare
BWI76_RS21370 -1.0 -1.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS19685 -1.0 -4.0 lysine transporter compare
BWI76_RS15765 -1.0 -2.1 hypothetical protein compare
BWI76_RS15830 -1.0 -1.8 hypothetical protein compare
BWI76_RS26000 -1.0 -5.3 aspartate aminotransferase family protein compare
BWI76_RS22645 -1.0 -3.5 RNA polymerase sigma factor RpoS compare
BWI76_RS08520 -1.0 -1.6 colicin transporter TolQ compare
BWI76_RS13420 -1.0 -1.6 ABC transporter permease compare
BWI76_RS06485 -1.0 -2.2 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS19040 -1.0 -3.9 hypothetical protein compare
BWI76_RS14915 -0.9 -1.8 hypothetical protein compare
BWI76_RS17770 -0.9 -1.6 isomerase/hydrolase compare
BWI76_RS15035 -0.9 -0.9 metal ABC transporter permease compare
BWI76_RS09190 -0.9 -2.3 hypothetical protein compare
BWI76_RS25160 -0.9 -1.7 transcription elongation factor GreA compare
BWI76_RS07760 -0.9 -3.2 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase compare
BWI76_RS15215 -0.9 -1.0 N-acetyltransferase compare
BWI76_RS26775 -0.9 -2.6 endo-1,4-D-glucanase compare
BWI76_RS25285 -0.9 -0.9 HPr family phosphocarrier protein compare
BWI76_RS19035 -0.9 -3.7 dTDP-rhamnosyl transferase compare
BWI76_RS15665 -0.9 -2.1 hypothetical protein compare
BWI76_RS15640 -0.9 -3.3 hypothetical protein compare
BWI76_RS15110 -0.9 -5.5 putative excinuclease ABC subunit A compare
BWI76_RS20440 -0.9 -1.2 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS26075 -0.9 -2.7 DNA adenine methylase compare
BWI76_RS00440 -0.9 -1.2 CopG family transcriptional regulator compare
BWI76_RS26405 -0.9 -1.3 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS10835 -0.9 -1.2 hypothetical protein compare
BWI76_RS13435 -0.9 -1.2 hypothetical protein compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare


Specific Phenotypes

For 6 genes in this experiment

For nitrogen source Gly-DL-Asp in Klebsiella michiganensis M5al

For nitrogen source Gly-DL-Asp across organisms