Experiment set6IT059 for Klebsiella michiganensis M5al

Compare to:

D-Alanine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS21810 +1.3 2.6 universal stress protein compare
BWI76_RS19770 +1.2 2.0 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS17470 +1.0 2.2 MerR family transcriptional regulator compare
BWI76_RS23320 +1.0 1.9 hypothetical protein compare
BWI76_RS08825 +1.0 2.5 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS07510 +1.0 3.3 hypothetical protein compare
BWI76_RS03595 +1.0 1.5 ethanolamine utilization protein EutM compare
BWI76_RS02785 +0.9 3.8 AIG2 family protein compare
BWI76_RS15350 +0.9 1.7 hypothetical protein compare
BWI76_RS02180 +0.9 1.2 hypothetical protein compare
BWI76_RS19465 +0.9 2.6 hypothetical protein compare
BWI76_RS18425 +0.9 2.2 phosphohydrolase compare
BWI76_RS14935 +0.9 1.4 NIPSNAP family containing protein compare
BWI76_RS10910 +0.8 2.9 hypothetical protein compare
BWI76_RS07805 +0.8 2.1 sugar ABC transporter permease compare
BWI76_RS11580 +0.8 2.7 L-asparaginase 1 compare
BWI76_RS13055 +0.8 4.4 NmrA family protein compare
BWI76_RS01775 +0.8 1.3 hypothetical protein compare
BWI76_RS11775 +0.8 2.5 2-deoxy-D-gluconate 3-dehydrogenase compare
BWI76_RS08405 +0.8 2.8 succinate dehydrogenase flavoprotein subunit compare
BWI76_RS09870 +0.8 3.6 aromatic amino acid aminotransferase compare
BWI76_RS09230 +0.8 1.4 hypothetical protein compare
BWI76_RS25000 +0.8 1.6 malonate decarboxylase acyl carrier protein compare
BWI76_RS04815 +0.8 2.3 cell division protein ZapD compare
BWI76_RS14775 +0.8 2.1 creatinine amidohydrolase compare
BWI76_RS24080 +0.8 1.0 DUF179 domain-containing protein compare
BWI76_RS09625 +0.8 1.4 hypothetical protein compare
BWI76_RS06130 +0.8 2.3 extensin family protein compare
BWI76_RS26590 +0.8 2.7 transcriptional regulator compare
BWI76_RS10575 +0.8 1.3 polar amino acid ABC transporter permease compare
BWI76_RS03825 +0.8 2.8 4-hydroxyphenylacetate 3-monooxygenase compare
BWI76_RS24035 +0.7 2.0 hypothetical protein compare
BWI76_RS17155 +0.7 1.5 hypothetical protein compare
BWI76_RS20885 +0.7 2.6 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS14300 +0.7 2.1 hypothetical protein compare
BWI76_RS24660 +0.7 2.6 autoinducer 2 ABC transporter ATP-binding protein LsrA compare
BWI76_RS09050 +0.7 2.5 MFS transporter compare
BWI76_RS11435 +0.7 1.7 hypothetical protein compare
BWI76_RS27200 +0.7 2.4 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL compare
BWI76_RS10745 +0.7 1.0 hypothetical protein compare
BWI76_RS12670 +0.7 1.8 DNA polymerase V subunit UmuD compare
BWI76_RS11980 +0.7 1.3 DeoR family transcriptional regulator compare
BWI76_RS11170 +0.7 1.2 hypothetical protein compare
BWI76_RS21245 +0.7 2.0 nitrogen regulatory protein P-II compare
BWI76_RS15920 +0.7 1.1 hypothetical protein compare
BWI76_RS06465 +0.7 0.8 IclR family transcriptional regulator compare
BWI76_RS13645 +0.7 2.2 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS16230 +0.7 1.9 dihydromonapterin reductase compare
BWI76_RS14735 +0.6 2.7 type 11 methyltransferase compare
BWI76_RS12485 +0.6 1.8 TyrR family transcriptional regulator compare
BWI76_RS06395 +0.6 2.3 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS23120 +0.6 2.0 propanediol dehydratase medium subunit compare
BWI76_RS08745 +0.6 3.1 proline-specific permease compare
BWI76_RS07640 +0.6 0.8 short chain dehydrogenase compare
BWI76_RS11265 +0.6 1.3 peptidase T compare
BWI76_RS05235 +0.6 0.9 hypothetical protein compare
BWI76_RS07785 +0.6 1.4 transcriptional regulator compare
BWI76_RS24345 +0.6 2.0 NADPH quinone reductase MdaB compare
BWI76_RS21675 +0.6 0.9 hypothetical protein compare
BWI76_RS16025 +0.6 1.3 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS24965 +0.6 1.7 SCP2 domain-containing protein compare
BWI76_RS08430 +0.6 2.0 succinate--CoA ligase subunit alpha compare
BWI76_RS13135 +0.6 1.2 3-oxoadipyl-CoA thiolase compare
BWI76_RS10725 +0.6 1.3 hypothetical protein compare
BWI76_RS15980 +0.6 1.6 lysine transporter LysE compare
BWI76_RS00600 +0.6 2.3 LacI family transcriptional regulator compare
BWI76_RS07810 +0.6 2.1 sugar ABC transporter periplasmic sugar-binding protein compare
BWI76_RS13170 +0.6 2.8 methyltransferase compare
BWI76_RS27460 +0.6 1.6 hypothetical protein compare
BWI76_RS01185 +0.6 1.2 adenylate cyclase compare
BWI76_RS15190 +0.6 3.3 GGDEF domain-containing protein compare
BWI76_RS05070 +0.6 1.4 type II secretion system protein GspH compare
BWI76_RS15290 +0.6 1.0 transcriptional regulator compare
BWI76_RS17765 +0.6 2.0 hypothetical protein compare
BWI76_RS01200 +0.6 1.0 diaminopimelate epimerase compare
BWI76_RS11820 +0.6 0.8 short-chain dehydrogenase/reductase SDR compare
BWI76_RS08645 +0.6 2.0 molybdate ABC transporter substrate-binding protein compare
BWI76_RS08330 +0.6 1.1 hypothetical protein compare
BWI76_RS12420 +0.6 0.9 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS06250 +0.6 2.3 alpha-glycosidase compare
BWI76_RS25925 +0.6 1.7 hypothetical protein compare
BWI76_RS27510 +0.6 1.9 aquaporin compare
BWI76_RS13710 +0.6 1.9 benzoate 1,2-dioxygenase small subunit compare
BWI76_RS22855 +0.6 1.5 hypothetical protein compare
BWI76_RS19520 +0.6 3.1 acetyltransferase GCN5 compare
BWI76_RS26875 +0.6 1.0 dipeptide ABC transporter permease DppC compare
BWI76_RS26015 +0.6 1.5 DUF2559 domain-containing protein compare
BWI76_RS27820 +0.6 1.1 ilvB operon leader peptide IvbL compare
BWI76_RS00710 +0.6 1.4 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS21570 +0.6 1.5 RnfH family protein compare
BWI76_RS11610 +0.5 1.1 glutamate dehydrogenase compare
BWI76_RS10375 +0.5 3.1 polar amino acid ABC transporter inner membrane subunit compare
BWI76_RS10245 +0.5 1.2 aspartate aminotransferase compare
BWI76_RS05350 +0.5 2.4 Rcs stress response system protein RcsF compare
BWI76_RS15020 +0.5 2.5 2-oxobutyrate oxidase compare
BWI76_RS20715 +0.5 1.3 RpoE-regulated lipoprotein compare
BWI76_RS07360 +0.5 2.9 phenylalanine transporter compare
BWI76_RS07730 +0.5 1.0 iron-enterobactin transporter membrane protein compare
BWI76_RS10475 +0.5 2.3 binding-protein-dependent transport system inner membrane protein compare
BWI76_RS06745 +0.5 0.8 N-acetyltransferase GCN5 compare
BWI76_RS19310 +0.5 1.8 ABC transporter permease compare
BWI76_RS19240 +0.5 1.2 ABC transporter substrate-binding protein compare
BWI76_RS05965 +0.5 1.0 hypothetical protein compare
BWI76_RS01060 +0.5 3.7 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
BWI76_RS20375 +0.5 0.5 membrane protein compare
BWI76_RS25865 +0.5 2.6 ferredoxin compare
BWI76_RS20785 +0.5 0.8 ethanolamine utilization protein EutJ compare
BWI76_RS07165 +0.5 2.1 hypothetical protein compare
BWI76_RS16840 +0.5 2.2 ABC transporter compare
BWI76_RS13630 +0.5 2.2 ABC transporter compare
BWI76_RS24020 +0.5 2.0 peptidase M48 compare
BWI76_RS08620 +0.5 1.9 galactose-1-phosphate uridylyltransferase compare
BWI76_RS09440 +0.5 1.1 hypothetical protein compare
BWI76_RS11125 +0.5 1.1 metal-dependent hydrolase compare
BWI76_RS13240 +0.5 0.9 hypothetical protein compare
BWI76_RS25905 +0.5 1.6 hypothetical protein compare
BWI76_RS08885 +0.5 2.3 transcriptional regulator compare
BWI76_RS11205 +0.5 1.6 transcription-repair coupling factor compare
BWI76_RS18745 +0.5 1.2 adenosylhomocysteinase compare
BWI76_RS23755 +0.5 1.7 transcriptional regulator compare
BWI76_RS01790 +0.5 3.5 lysine-sensitive aspartokinase 3 compare
BWI76_RS07565 +0.5 2.1 LysE type translocator family protein compare
BWI76_RS19935 +0.5 1.0 hypothetical protein compare
BWI76_RS26960 +0.5 1.8 bifunctional glyoxylate/hydroxypyruvate reductase B compare
BWI76_RS16455 +0.5 1.0 superoxide dismutase compare
BWI76_RS04605 +0.5 0.9 thiamine ABC transporter ATP-binding protein compare
BWI76_RS14825 +0.5 1.0 dienelactone hydrolase family protein compare
BWI76_RS09515 +0.5 1.9 arginine ABC transporter substrate-binding protein compare
BWI76_RS10995 +0.5 2.7 lipoprotein compare
BWI76_RS23530 +0.5 1.1 MarR family transcriptional regulator compare
BWI76_RS06120 +0.5 1.4 membrane protein compare
BWI76_RS14170 +0.5 1.5 hypothetical protein compare
BWI76_RS15970 +0.5 1.8 carboxypeptidase M32 compare
BWI76_RS00720 +0.5 1.1 DNA-binding response regulator compare
BWI76_RS20390 +0.5 1.1 erythronate-4-phosphate dehydrogenase compare
BWI76_RS14000 +0.5 2.0 glutamine amidotransferase compare
BWI76_RS05025 +0.5 1.5 2'-5' RNA ligase compare
BWI76_RS14540 +0.5 1.2 yersiniabactin biosynthetic protein YbtU compare
BWI76_RS13960 +0.5 1.1 urea ABC transporter periplasmic protein compare
BWI76_RS00885 +0.5 1.8 tRNA (uridine(54)-C5)-methyltransferase TrmA compare
BWI76_RS13545 +0.5 0.9 N-acetyltransferase compare
BWI76_RS15900 +0.5 2.1 hypothetical protein compare
BWI76_RS19910 +0.5 2.6 phosphotransferase RcsD compare
BWI76_RS22815 +0.5 3.3 hybrid sensor histidine kinase/response regulator compare
BWI76_RS06190 +0.5 1.2 hypothetical protein compare
BWI76_RS20310 +0.5 2.1 hypothetical protein compare
BWI76_RS13810 +0.5 3.0 MarR family transcriptional regulator compare
BWI76_RS17525 +0.5 0.7 XshC-Cox1-family protein compare
BWI76_RS18225 +0.5 1.9 universal stress protein C compare
BWI76_RS21660 +0.5 1.0 antirestriction protein compare
BWI76_RS16035 +0.5 1.8 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS18845 +0.5 2.4 nitrogen fixation protein NifX compare
BWI76_RS02865 +0.5 2.3 hypothetical protein compare
BWI76_RS03865 +0.5 2.2 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase compare
BWI76_RS21345 +0.5 0.9 sigma-E factor regulatory protein RseB compare
BWI76_RS27350 +0.5 1.7 hypothetical protein compare
BWI76_RS16130 +0.5 1.6 3-carboxy-cis,cis-muconate cycloisomerase compare
BWI76_RS16535 +0.5 2.9 MATE family efflux transporter compare
BWI76_RS24925 +0.5 0.9 DnaA initiator-associating protein DiaA compare
BWI76_RS12680 +0.5 1.1 oxidoreductase compare
BWI76_RS05655 +0.5 0.8 hypothetical protein compare
BWI76_RS06335 +0.5 1.7 nucleoside-specific channel-forming protein Tsx compare
BWI76_RS24765 +0.5 1.0 membrane protein compare
BWI76_RS26155 +0.5 3.2 phosphoenolpyruvate carboxykinase (ATP) compare
BWI76_RS05525 +0.5 1.1 glycerophosphodiester phosphodiesterase compare
BWI76_RS13110 +0.5 1.5 phenylacetic acid degradation protein compare
BWI76_RS12615 +0.4 2.0 LysR family transcriptional regulator compare
BWI76_RS04275 +0.4 1.9 molybdopterin adenylyltransferase compare
BWI76_RS18565 +0.4 1.5 pemk protein compare
BWI76_RS15915 +0.4 2.0 YnfC family lipoprotein compare
BWI76_RS23735 +0.4 2.0 sugar diacid utilization regulator compare
BWI76_RS10875 +0.4 2.0 quercetin 2,3-dioxygenase compare
BWI76_RS04200 +0.4 2.2 phosphoglycerate mutase GpmB compare
BWI76_RS09710 +0.4 1.2 transketolase compare
BWI76_RS09490 +0.4 1.5 DNA-binding response regulator compare
BWI76_RS13050 +0.4 1.1 transcriptional regulator compare
BWI76_RS22110 +0.4 2.6 putative helix-turn-helix AraC-type transcriptional regulator compare
BWI76_RS14835 +0.4 0.8 hypothetical protein compare
BWI76_RS12875 +0.4 1.5 bifunctional deaminase-reductase compare
BWI76_RS09165 +0.4 1.3 phosphatase YbjI compare
BWI76_RS22185 +0.4 1.5 hypothetical protein compare
BWI76_RS17805 +0.4 0.7 membrane protein compare
BWI76_RS00655 +0.4 1.7 inner-membrane translocator compare
BWI76_RS24825 +0.4 0.9 2-hydroxy-3-oxopropionate reductase compare
BWI76_RS14860 +0.4 2.2 ABC transporter compare
BWI76_RS08510 +0.4 1.5 cyd operon protein YbgE compare
BWI76_RS19100 +0.4 1.7 putative acid phosphatase compare
BWI76_RS12550 +0.4 0.9 hypothetical protein compare
BWI76_RS13215 +0.4 0.8 type I glyceraldehyde-3-phosphate dehydrogenase compare
BWI76_RS13480 +0.4 0.9 XRE family transcriptional regulator compare
BWI76_RS06435 +0.4 1.1 MFS transporter compare
BWI76_RS16085 +0.4 1.5 two-component system sensor histidine kinase DcuS compare
BWI76_RS26260 +0.4 1.3 hypothetical protein compare
BWI76_RS16160 +0.4 1.3 LysR family transcriptional regulator compare
BWI76_RS20225 +0.4 1.1 hypothetical protein compare
BWI76_RS19140 +0.4 1.7 citrate (Si)-synthase compare
BWI76_RS21360 +0.4 2.9 L-aspartate oxidase compare
BWI76_RS17375 +0.4 0.8 nitrate ABC transporter, permease protein compare
BWI76_RS16420 +0.4 2.1 anhydro-N-acetylmuramic acid kinase compare
BWI76_RS09630 +0.4 1.3 leucyl/phenylalanyl-tRNA--protein transferase compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source D-Alanine in Klebsiella michiganensis M5al

For nitrogen source D-Alanine across organisms