Experiment set6IT058 for Klebsiella michiganensis M5al

Compare to:

D-Serine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20355 -8.9 -6.1 colicin V production protein compare
BWI76_RS00805 -8.8 -6.0 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS04250 -8.3 -5.8 homoserine kinase compare
BWI76_RS25115 -8.2 -5.7 argininosuccinate synthase compare
BWI76_RS18925 -7.9 -5.5 histidinol dehydrogenase compare
BWI76_RS00850 -7.8 -8.2 acetylglutamate kinase compare
BWI76_RS00990 -7.8 -7.6 ketol-acid reductoisomerase compare
BWI76_RS04470 -7.6 -7.4 carbamoyl phosphate synthase large subunit compare
BWI76_RS18930 -7.6 -6.0 histidinol-phosphate transaminase compare
BWI76_RS00980 -7.6 -7.4 PLP-dependent threonine dehydratase compare
BWI76_RS04245 -7.4 -10.2 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS18920 -7.4 -5.1 ATP phosphoribosyltransferase compare
BWI76_RS20895 -7.4 -5.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS18935 -7.3 -8.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00855 -7.3 -7.1 argininosuccinate lyase compare
BWI76_RS07070 -7.3 -5.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS05835 -7.3 -5.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS01655 -7.2 -8.2 homoserine O-succinyltransferase compare
BWI76_RS21265 -7.1 -14.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS11965 -6.9 -5.0 orotidine-5'-phosphate decarboxylase compare
BWI76_RS24285 -6.9 -8.2 cystathionine beta-lyase compare
BWI76_RS05840 -6.9 -4.8 glutamate 5-kinase compare
BWI76_RS23220 -6.8 -8.1 amino-acid N-acetyltransferase compare
BWI76_RS04670 -6.8 -9.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS18950 -6.8 -5.6 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS11850 -6.8 -9.5 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS09760 -6.7 -4.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS27385 -6.7 -6.5 orotate phosphoribosyltransferase compare
BWI76_RS00985 -6.7 -6.5 transcriptional regulator IlvY compare
BWI76_RS04685 -6.6 -7.9 putative leucine operon leader peptide compare
BWI76_RS04255 -6.6 -9.1 threonine synthase compare
BWI76_RS18940 -6.6 -6.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08385 -6.6 -3.9 citrate (Si)-synthase compare
BWI76_RS21475 -6.6 -5.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04665 -6.5 -18.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS20350 -6.3 -6.4 amidophosphoribosyltransferase compare
BWI76_RS11860 -6.3 -9.6 anthranilate synthase component I compare
BWI76_RS25320 -6.3 -11.0 glutamate synthase compare
BWI76_RS00785 -6.2 -7.4 cystathionine gamma-synthase compare
BWI76_RS23360 -6.2 -4.3 diaminopimelate decarboxylase compare
BWI76_RS18955 -6.2 -5.3 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS00845 -6.1 -10.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS09755 -6.0 -10.1 phosphoserine transaminase compare
BWI76_RS05015 -6.0 -4.1 transcriptional regulator compare
BWI76_RS26085 -5.9 -4.0 3-dehydroquinate synthase compare
BWI76_RS07065 -5.9 -9.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23365 -5.8 -6.2 LysR family transcriptional regulator compare
BWI76_RS20965 -5.7 -4.0 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS03010 -5.7 -8.4 ornithine carbamoyltransferase compare
BWI76_RS25315 -5.7 -11.1 glutamate synthase large subunit compare
BWI76_RS01610 -5.7 -6.4 phosphoribosylamine--glycine ligase compare
BWI76_RS04680 -5.7 -14.6 2-isopropylmalate synthase compare
BWI76_RS00835 -5.6 -14.8 phosphoenolpyruvate carboxylase compare
BWI76_RS04675 -5.6 -8.6 3-isopropylmalate dehydrogenase compare
BWI76_RS02995 -5.5 -8.8 aspartate carbamoyltransferase compare
BWI76_RS04645 -5.4 -6.5 3-dehydroquinase compare
BWI76_RS01615 -5.4 -12.6 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11855 -5.4 -5.7 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS11840 -5.4 -4.4 tryptophan synthase subunit alpha compare
BWI76_RS09910 -5.3 -18.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS17720 -5.3 -2.1 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS02530 -5.2 -3.6 tRNA dimethylallyltransferase compare
BWI76_RS25645 -5.2 -8.6 shikimate dehydrogenase compare
BWI76_RS26000 -5.1 -8.3 aspartate aminotransferase family protein compare
BWI76_RS02735 -5.1 -4.1 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS22805 -5.1 -9.0 GTP diphosphokinase compare
BWI76_RS22760 -5.1 -8.9 sulfite reductase subunit beta compare
BWI76_RS00400 -5.0 -3.3 glutamine synthetase compare
BWI76_RS22765 -5.0 -15.0 sulfite reductase subunit alpha compare
BWI76_RS04465 -4.9 -5.4 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23920 -4.8 -7.8 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS27390 -4.7 -4.0 ribonuclease PH compare
BWI76_RS09655 -4.7 -6.1 leucine-responsive regulatory protein compare
BWI76_RS27860 -4.6 -11.2 D-serine dehydratase conserved
BWI76_RS22755 -4.5 -8.2 phosphoadenosine phosphosulfate reductase compare
BWI76_RS11845 -4.5 -2.7 tryptophan synthase subunit beta compare
BWI76_RS00975 -4.5 -6.6 dihydroxy-acid dehydratase compare
BWI76_RS04160 -4.4 -7.0 phosphoserine phosphatase compare
BWI76_RS27850 -4.3 -7.0 DNA-binding transcriptional regulator DsdC conserved
BWI76_RS04240 -4.0 -2.7 thr operon leader peptide compare
BWI76_RS26455 -3.9 -5.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS05120 -3.9 -7.7 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS22690 -3.8 -5.1 adenylyl-sulfate kinase compare
BWI76_RS06525 -3.8 -4.1 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS26055 -3.8 -9.9 siroheme synthase compare
BWI76_RS00385 -3.6 -8.0 nitrogen assimilation regulatory protein compare
BWI76_RS10990 -3.6 -2.1 dihydroorotase compare
BWI76_RS21465 -3.6 -5.4 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS09645 -3.6 -2.0 thioredoxin-disulfide reductase compare
BWI76_RS00965 -3.5 -1.9 acetolactate synthase 2 small subunit compare
BWI76_RS00390 -3.5 -5.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS25600 -3.4 -1.9 tRNA-Thr compare
BWI76_RS26460 -3.3 -7.1 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS20640 -3.2 -6.2 cysteine synthase A compare
BWI76_RS01350 -3.0 -1.7 NAD(P)H-flavin reductase compare
BWI76_RS20435 -2.9 -1.5 chorismate synthase compare
BWI76_RS12145 -2.9 -2.8 hypothetical protein compare
BWI76_RS00960 -2.9 -7.6 acetolactate synthase 2 catalytic subunit compare
BWI76_RS05200 -2.7 -4.1 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS23230 -2.7 -5.4 exodeoxyribonuclease V subunit beta compare
BWI76_RS26570 -2.6 -3.6 anion permease compare
BWI76_RS17980 -2.6 -4.6 RNA chaperone ProQ compare
BWI76_RS08525 -2.5 -3.5 colicin transporter compare
BWI76_RS25060 -2.5 -4.1 lipoprotein NlpI compare
BWI76_RS23240 -2.4 -4.1 exonuclease V subunit gamma compare
BWI76_RS09650 -2.3 -6.1 hypothetical protein compare
BWI76_RS27855 -2.3 -4.4 D-serine transporter DsdX compare
BWI76_RS01200 -2.2 -2.2 diaminopimelate epimerase compare
BWI76_RS21140 -2.2 -3.0 molecular chaperone HscA compare
BWI76_RS01210 -2.2 -2.5 tyrosine recombinase XerC compare
BWI76_RS09970 -2.1 -6.3 porin OmpA compare
BWI76_RS20440 -2.1 -1.4 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS21310 -2.0 -1.6 DNA repair protein RecO compare
BWI76_RS02985 -2.0 -5.8 reactive intermediate/imine deaminase compare
BWI76_RS17290 -2.0 -6.4 formyltetrahydrofolate deformylase compare
BWI76_RS25070 -2.0 -1.9 hypothetical protein compare
BWI76_RS04270 -2.0 -5.7 transaldolase compare
BWI76_RS14305 -1.9 -4.4 metallophosphoesterase compare
BWI76_RS02410 -1.8 -2.3 EF-P beta-lysylation protein EpmB compare
BWI76_RS16965 -1.8 -5.4 murein lipoprotein compare
BWI76_RS08580 -1.8 -4.2 quinolinate synthetase compare
BWI76_RS25065 -1.8 -2.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS02990 -1.7 -4.5 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS21480 -1.6 -3.1 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS04845 -1.5 -7.4 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS20650 -1.5 -2.1 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19010 -1.5 -3.4 polysaccharide pyruvyl transferase yvff compare
BWI76_RS10955 -1.4 -2.3 hypothetical protein compare
BWI76_RS09615 -1.4 -1.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS06295 -1.4 -6.2 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS06185 -1.4 -5.7 shikimate kinase II compare
BWI76_RS06765 -1.4 -3.6 transcriptional regulator compare
BWI76_RS24465 -1.4 -8.4 adenylate cyclase compare
BWI76_RS15110 -1.4 -8.9 putative excinuclease ABC subunit A compare
BWI76_RS25960 -1.4 -2.6 NUDIX hydrolase compare
BWI76_RS25335 -1.4 -1.7 stringent starvation protein A compare
BWI76_RS24900 -1.4 -1.6 DeoR family transcriptional regulator compare
BWI76_RS26620 -1.4 -1.3 Fe-S biogenesis protein NfuA compare
BWI76_RS12195 -1.3 -2.4 hypothetical protein compare
BWI76_RS07730 -1.3 -1.6 iron-enterobactin transporter membrane protein compare
BWI76_RS01385 -1.3 -2.4 potassium transporter compare
BWI76_RS13095 -1.3 -1.3 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS16485 -1.3 -2.3 ribonuclease T compare
BWI76_RS14650 -1.3 -2.0 helix-turn-helix transcriptional regulator compare
BWI76_RS06535 -1.3 -4.3 endopeptidase La compare
BWI76_RS06530 -1.3 -5.2 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS27430 -1.3 -1.3 (p)ppGpp synthetase compare
BWI76_RS21370 -1.3 -0.9 ATP-dependent RNA helicase SrmB compare
BWI76_RS17975 -1.2 -4.8 tail-specific protease compare
BWI76_RS04530 -1.2 -1.0 peptidylprolyl isomerase SurA compare
BWI76_RS20970 -1.2 -1.5 phosphoribosylglycinamide formyltransferase compare
BWI76_RS21070 -1.2 -2.4 outer membrane protein assembly factor BamB compare
BWI76_RS08395 -1.2 -2.2 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS23480 -1.2 -7.0 EAL domain-containing protein compare
BWI76_RS22695 -1.2 -4.6 sulfate adenylyltransferase compare
BWI76_RS24460 -1.2 -4.9 bifunctional glutamine synthetase adenylyltransferase/deadenyltransferase compare
BWI76_RS18770 -1.2 -1.2 DNA gyrase inhibitor compare
BWI76_RS14625 -1.2 -1.3 protein TolA compare
BWI76_RS08520 -1.2 -2.9 colicin transporter TolQ compare
BWI76_RS09190 -1.2 -2.9 hypothetical protein compare
BWI76_RS19690 -1.2 -2.6 LysR family transcriptional regulator compare
BWI76_RS18755 -1.1 -1.4 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS04705 -1.1 -4.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS15990 -1.1 -4.5 serine protease compare
BWI76_RS19685 -1.1 -3.4 lysine transporter compare
BWI76_RS15835 -1.1 -0.7 hypothetical protein compare
BWI76_RS09610 -1.1 -2.5 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS13595 -1.1 -3.4 transcriptional regulator compare
BWI76_RS15115 -1.1 -4.6 MFS transporter compare
BWI76_RS14415 -1.1 -2.0 transcriptional regulator, TetR family protein compare
BWI76_RS22955 -1.1 -2.6 transcriptional regulator GcvA compare
BWI76_RS01935 -1.1 -2.2 thiamin phosphate synthase compare
BWI76_RS15060 -1.1 -2.2 MarR family transcriptional regulator compare
BWI76_RS20995 -1.1 -4.2 RNA degradosome polyphosphate kinase compare
BWI76_RS22950 -1.1 -1.7 membrane protein compare
BWI76_RS25870 -1.1 -1.7 elongation factor Tu compare
BWI76_RS08380 -1.1 -0.9 endonuclease VIII compare
BWI76_RS26575 -1.1 -2.0 universal stress protein B compare
BWI76_RS11155 -1.1 -1.3 penicillin-binding protein activator LpoB compare
BWI76_RS14320 -1.0 -1.9 hypothetical protein compare
BWI76_RS24260 -1.0 -2.3 hypothetical protein compare
BWI76_RS19870 -1.0 -1.6 malate:quinone oxidoreductase compare
BWI76_RS17065 -1.0 -5.3 phosphoenolpyruvate synthase compare
BWI76_RS19700 -1.0 -2.2 deoxyribonuclease IV compare
BWI76_RS16210 -1.0 -1.3 hypothetical protein compare
BWI76_RS06190 -1.0 -1.7 hypothetical protein compare
BWI76_RS16275 -1.0 -2.3 fumarate hydratase FumA compare
BWI76_RS17770 -1.0 -2.1 isomerase/hydrolase compare
BWI76_RS07475 -1.0 -1.0 DNA-binding transcriptional regulator RamA compare
BWI76_RS20380 -1.0 -1.2 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS25285 -1.0 -1.0 HPr family phosphocarrier protein compare
BWI76_RS00940 -1.0 -3.8 transcriptional regulator HdfR compare
BWI76_RS12860 -1.0 -1.4 hypothetical protein compare
BWI76_RS21285 -1.0 -1.6 HAD family hydrolase compare
BWI76_RS08535 -0.9 -1.4 translocation protein TolB compare
BWI76_RS09660 -0.9 -1.2 DNA translocase FtsK compare
BWI76_RS13755 -0.9 -1.5 hypothetical protein compare
BWI76_RS25425 -0.9 -1.8 arginine repressor compare
BWI76_RS24025 -0.9 -4.1 agmatinase compare
BWI76_RS25355 -0.9 -4.1 cell division protein ZapE compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source D-Serine in Klebsiella michiganensis M5al

For nitrogen source D-Serine across organisms