Experiment set6IT054 for Klebsiella michiganensis M5al

Compare to:

L-Leucine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18950 -7.2 -6.6 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS11965 -7.0 -5.3 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23920 -7.0 -6.8 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS18940 -6.7 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00390 -6.3 -7.6 two-component system sensor histidine kinase NtrB compare
BWI76_RS18925 -6.3 -8.2 histidinol dehydrogenase compare
BWI76_RS18930 -6.3 -4.7 histidinol-phosphate transaminase compare
BWI76_RS04470 -6.2 -11.6 carbamoyl phosphate synthase large subunit compare
BWI76_RS01210 -6.1 -4.1 tyrosine recombinase XerC compare
BWI76_RS05015 -6.1 -4.2 transcriptional regulator compare
BWI76_RS18935 -6.1 -6.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS26085 -5.9 -3.7 3-dehydroquinate synthase compare
BWI76_RS09755 -5.7 -5.3 phosphoserine transaminase compare
BWI76_RS10990 -5.5 -3.0 dihydroorotase compare
BWI76_RS02995 -5.5 -11.1 aspartate carbamoyltransferase compare
BWI76_RS00385 -5.4 -9.2 nitrogen assimilation regulatory protein compare
BWI76_RS09645 -5.3 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS00850 -5.1 -7.8 acetylglutamate kinase compare
BWI76_RS00400 -5.1 -3.1 glutamine synthetase compare
BWI76_RS23360 -5.0 -5.7 diaminopimelate decarboxylase compare
BWI76_RS08180 -4.8 -9.4 asparagine synthase B compare
BWI76_RS21265 -4.7 -13.5 phosphoribosylformylglycinamidine synthase compare
BWI76_RS09910 -4.7 -17.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS01610 -4.7 -9.3 phosphoribosylamine--glycine ligase compare
BWI76_RS27385 -4.7 -6.1 orotate phosphoribosyltransferase compare
BWI76_RS03010 -4.6 -6.7 ornithine carbamoyltransferase compare
BWI76_RS23220 -4.6 -7.2 amino-acid N-acetyltransferase compare
BWI76_RS04465 -4.6 -6.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23230 -4.6 -3.2 exodeoxyribonuclease V subunit beta compare
BWI76_RS20355 -4.6 -2.6 colicin V production protein compare
BWI76_RS00855 -4.5 -7.5 argininosuccinate lyase compare
BWI76_RS04160 -4.4 -10.9 phosphoserine phosphatase compare
BWI76_RS18920 -4.4 -3.3 ATP phosphoribosyltransferase compare
BWI76_RS07070 -4.4 -7.8 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -4.3 -13.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS20895 -4.2 -5.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS20965 -4.2 -3.8 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23240 -4.1 -4.9 exonuclease V subunit gamma compare
BWI76_RS00845 -4.0 -9.7 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS15825 -4.0 -2.6 hypothetical protein compare
BWI76_RS08385 -4.0 -4.8 citrate (Si)-synthase compare
BWI76_RS05200 -3.9 -3.8 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00975 -3.7 -11.5 dihydroxy-acid dehydratase compare
BWI76_RS20350 -3.7 -5.3 amidophosphoribosyltransferase compare
BWI76_RS27390 -3.4 -5.7 ribonuclease PH compare
BWI76_RS09660 -3.4 -3.2 DNA translocase FtsK compare
BWI76_RS00835 -3.3 -13.8 phosphoenolpyruvate carboxylase compare
BWI76_RS08525 -3.3 -4.9 colicin transporter compare
BWI76_RS25070 -3.3 -2.1 hypothetical protein compare
BWI76_RS06530 -3.3 -6.3 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS20380 -3.2 -2.0 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS27430 -3.2 -1.6 (p)ppGpp synthetase compare
BWI76_RS25115 -3.2 -4.9 argininosuccinate synthase compare
BWI76_RS08535 -3.2 -2.9 translocation protein TolB compare
BWI76_RS05840 -3.2 -7.1 glutamate 5-kinase compare
BWI76_RS05835 -3.1 -3.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS26570 -3.1 -4.5 anion permease compare
BWI76_RS20435 -3.0 -1.4 chorismate synthase compare
BWI76_RS17980 -3.0 -4.3 RNA chaperone ProQ compare
BWI76_RS06525 -2.9 -3.6 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS09760 -2.7 -8.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS02530 -2.6 -2.5 tRNA dimethylallyltransferase compare
BWI76_RS22805 -2.6 -9.8 GTP diphosphokinase compare
BWI76_RS00345 -2.6 -5.3 protein disulfide oxidoreductase DsbA compare
BWI76_RS23480 -2.6 -12.6 EAL domain-containing protein compare
BWI76_RS17720 -2.6 -1.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS08530 -2.6 -3.4 protein TolA compare
BWI76_RS12090 -2.5 -3.0 HNH endonuclease compare
BWI76_RS02410 -2.5 -2.5 EF-P beta-lysylation protein EpmB compare
BWI76_RS17975 -2.4 -6.7 tail-specific protease compare
BWI76_RS18630 -2.4 -5.2 nitrogen assimilation transcriptional regulator compare
BWI76_RS00965 -2.4 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS11845 -2.4 -4.9 tryptophan synthase subunit beta compare
BWI76_RS26075 -2.2 -3.3 DNA adenine methylase compare
BWI76_RS00840 -2.2 -8.1 acetylornithine deacetylase compare
BWI76_RS21370 -2.2 -2.2 ATP-dependent RNA helicase SrmB compare
BWI76_RS18385 -2.2 -1.7 hypothetical protein compare
BWI76_RS24240 -2.2 -2.5 hypothetical protein compare
BWI76_RS04645 -2.1 -5.0 3-dehydroquinase compare
BWI76_RS16965 -2.1 -6.0 murein lipoprotein compare
BWI76_RS11850 -2.0 -8.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS07065 -2.0 -6.4 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS23365 -2.0 -4.9 LysR family transcriptional regulator compare
BWI76_RS17345 -2.0 -5.8 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS09970 -2.0 -6.2 porin OmpA compare
BWI76_RS22755 -1.9 -4.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS08520 -1.8 -2.2 colicin transporter TolQ compare
BWI76_RS05235 -1.8 -1.4 hypothetical protein compare
BWI76_RS25960 -1.8 -5.5 NUDIX hydrolase compare
BWI76_RS23265 -1.8 -1.6 hypothetical protein compare
BWI76_RS25335 -1.8 -4.4 stringent starvation protein A compare
BWI76_RS11840 -1.7 -5.3 tryptophan synthase subunit alpha compare
BWI76_RS25065 -1.7 -2.2 polyribonucleotide nucleotidyltransferase compare
BWI76_RS17735 -1.7 -4.1 D-amino acid dehydrogenase small subunit compare
BWI76_RS21505 -1.7 -1.4 hypothetical protein compare
BWI76_RS06535 -1.6 -3.3 endopeptidase La compare
BWI76_RS24235 -1.6 -5.7 Branched-chain-amino-acid transaminase (EC 2.6.1.42) (from data) conserved
BWI76_RS15990 -1.6 -5.1 serine protease compare
BWI76_RS06395 -1.6 -3.1 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS16235 -1.5 -4.7 membrane protein compare
BWI76_RS01775 -1.5 -1.3 hypothetical protein compare
BWI76_RS05985 -1.5 -5.8 branched-chain amino acid ABC transporter permease compare
BWI76_RS21565 -1.5 -1.4 outer membrane protein assembly factor BamE compare
BWI76_RS19010 -1.4 -2.6 polysaccharide pyruvyl transferase yvff compare
BWI76_RS15835 -1.4 -0.9 hypothetical protein compare
BWI76_RS25600 -1.4 -1.3 tRNA-Thr compare
BWI76_RS21070 -1.4 -1.6 outer membrane protein assembly factor BamB compare
BWI76_RS00430 -1.4 -3.5 GNAT family N-acetyltransferase compare
BWI76_RS27440 -1.4 -3.6 DNA helicase RecG compare
BWI76_RS00970 -1.4 -2.6 branched chain amino acid aminotransferase compare
BWI76_RS07185 -1.3 -1.4 hypothetical protein compare
BWI76_RS05450 -1.3 -1.4 ribonuclease HI compare
BWI76_RS05120 -1.3 -5.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS24340 -1.3 -5.2 two-component sensor histidine kinase compare
BWI76_RS05975 -1.3 -2.7 ABC transporter ATP-binding protein compare
BWI76_RS26395 -1.2 -4.0 cell division protein FtsE compare
BWI76_RS19845 -1.2 -3.3 phosphatase compare
BWI76_RS04270 -1.2 -4.1 transaldolase compare
BWI76_RS19870 -1.2 -2.4 malate:quinone oxidoreductase compare
BWI76_RS25280 -1.2 -1.7 RNase adaptor protein RapZ compare
BWI76_RS15840 -1.2 -2.3 prophage protein compare
BWI76_RS15830 -1.2 -1.9 hypothetical protein compare
BWI76_RS25060 -1.2 -2.2 lipoprotein NlpI compare
BWI76_RS26055 -1.2 -4.6 siroheme synthase compare
BWI76_RS02550 -1.1 -3.3 protease modulator HflC compare
BWI76_RS21450 -1.1 -2.5 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS19840 -1.1 -1.2 hypothetical protein compare
BWI76_RS14005 -1.1 -1.8 TetR family transcriptional regulator compare
BWI76_RS15850 -1.1 -1.1 DUF1317 domain-containing protein compare
BWI76_RS09960 -1.1 -2.5 Lon protease compare
BWI76_RS26455 -1.1 -3.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS06765 -1.1 -2.4 transcriptional regulator compare
BWI76_RS00940 -1.1 -4.1 transcriptional regulator HdfR compare
BWI76_RS22690 -1.1 -3.2 adenylyl-sulfate kinase compare
BWI76_RS24885 -1.1 -1.3 PTS galactitol transporter subunit IIB compare
BWI76_RS05990 -1.1 -3.4 branched-chain amino acid ABC transporter permease compare
BWI76_RS14325 -1.1 -1.8 maturase compare
BWI76_RS15810 -1.1 -3.5 hypothetical protein compare
BWI76_RS18715 -1.0 -3.9 hypothetical protein compare
BWI76_RS01350 -1.0 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS06770 -1.0 -6.0 Hha toxicity attenuator compare
BWI76_RS16935 -1.0 -1.4 shikimate dehydrogenase compare
BWI76_RS13560 -1.0 -1.1 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS04255 -1.0 -3.9 threonine synthase compare
BWI76_RS26390 -1.0 -3.3 cell division protein FtsX compare
BWI76_RS18955 -1.0 -1.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS20700 -1.0 -2.4 sulfate/thiosulfate transporter subunit compare
BWI76_RS12450 -1.0 -1.2 phage shock protein PspA compare
BWI76_RS11040 -1.0 -3.1 ribonuclease E compare
BWI76_RS23885 -1.0 -1.3 2-octaprenylphenol hydroxylase compare
BWI76_RS03800 -1.0 -2.9 hypothetical protein compare
BWI76_RS26175 -1.0 -2.3 DeoR/GlpR family transcriptional regulator compare
BWI76_RS08925 -1.0 -3.8 DNA-binding protein YbiB compare
BWI76_RS26440 -1.0 -1.3 hypothetical protein compare
BWI76_RS00990 -1.0 -4.3 ketol-acid reductoisomerase compare
BWI76_RS19685 -0.9 -3.6 lysine transporter compare
BWI76_RS11855 -0.9 -3.8 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS09470 -0.9 -1.9 putrescine ABC transporter permease compare
BWI76_RS16485 -0.9 -1.6 ribonuclease T compare
BWI76_RS10770 -0.9 -2.7 pyrimidine utilization protein C compare
BWI76_RS20650 -0.9 -1.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS13325 -0.9 -2.6 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS11125 -0.9 -1.3 metal-dependent hydrolase compare
BWI76_RS23760 -0.9 -1.4 tRNA-Gly compare
BWI76_RS22765 -0.9 -5.2 sulfite reductase subunit alpha compare
BWI76_RS04570 -0.9 -3.9 RNA polymerase-associated protein RapA compare
BWI76_RS19035 -0.9 -4.0 dTDP-rhamnosyl transferase compare
BWI76_RS04305 -0.9 -1.0 molecular chaperone DnaJ compare
BWI76_RS22630 -0.9 -2.9 LysR family transcriptional regulator compare
BWI76_RS11860 -0.9 -4.8 anthranilate synthase component I compare
BWI76_RS09940 -0.9 -3.1 paraquat-inducible protein B compare
BWI76_RS17300 -0.9 -1.0 tRNA-Tyr compare
BWI76_RS09030 -0.9 -3.0 transpeptidase compare
BWI76_RS20705 -0.9 -2.7 thiosulfate transporter subunit compare
BWI76_RS15635 -0.9 -3.0 hypothetical protein compare
BWI76_RS10060 -0.9 -1.2 acylphosphatase compare
BWI76_RS22760 -0.9 -3.2 sulfite reductase subunit beta compare
BWI76_RS03105 -0.9 -0.8 myo-inosose-2 dehydratase compare
BWI76_RS21350 -0.9 -1.7 anti-RNA polymerase sigma factor SigE compare
BWI76_RS16955 -0.9 -0.8 hypothetical protein compare
BWI76_RS08705 -0.9 -3.1 putative LuxR family regulatory protein compare
BWI76_RS15770 -0.9 -3.0 hypothetical protein compare
BWI76_RS18595 -0.9 -3.2 hypothetical protein compare
BWI76_RS05980 -0.9 -5.0 ABC transporter ATP-binding protein compare
BWI76_RS01205 -0.9 -1.6 DUF484 family protein compare
BWI76_RS23270 -0.8 -5.6 phosphoenolpyruvate--protein phosphotransferase PtsP compare
BWI76_RS12750 -0.8 -2.6 hypothetical protein compare
BWI76_RS17880 -0.8 -3.7 c-di-GMP phosphodiesterase compare
BWI76_RS02545 -0.8 -3.7 protease modulator HflK compare
BWI76_RS13755 -0.8 -1.3 hypothetical protein compare
BWI76_RS06000 -0.8 -6.0 ethanolamine ammonia-lyase small subunit compare
BWI76_RS14075 -0.8 -1.0 TetR family transcriptional regulator compare
BWI76_RS21980 -0.8 -2.1 hypothetical protein compare
BWI76_RS16795 -0.8 -1.4 amino acid ABC transporter ATPase compare
BWI76_RS26460 -0.8 -3.9 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS15695 -0.8 -1.7 hypothetical protein compare
BWI76_RS16120 -0.8 -2.2 4-carboxymuconolactone decarboxylase compare
BWI76_RS01185 -0.8 -1.6 adenylate cyclase compare
BWI76_RS18710 -0.8 -5.2 GGDEF-domain containing protein compare
BWI76_RS04530 -0.8 -1.0 peptidylprolyl isomerase SurA compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Leucine in Klebsiella michiganensis M5al

For nitrogen source L-Leucine across organisms