Experiment set6IT054 for Klebsiella michiganensis M5al

Compare to:

L-Leucine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS25425 +5.1 22.8 arginine repressor compare
BWI76_RS20995 +2.2 12.0 RNA degradosome polyphosphate kinase compare
BWI76_RS10700 +1.9 2.4 XRE family transcriptional regulator compare
BWI76_RS09655 +1.9 11.1 leucine-responsive regulatory protein compare
BWI76_RS23535 +1.6 10.2 hypothetical protein compare
BWI76_RS09650 +1.6 8.8 hypothetical protein compare
BWI76_RS06595 +1.5 4.9 hypothetical protein compare
BWI76_RS02180 +1.5 2.5 hypothetical protein compare
BWI76_RS20910 +1.4 9.5 glycine cleavage system transcriptional repressor compare
BWI76_RS23540 +1.4 7.6 putative lysine exporter protein compare
BWI76_RS24575 +1.3 2.3 hypothetical protein compare
BWI76_RS19705 +1.3 4.6 kinase compare
BWI76_RS26890 +1.2 2.3 hypothetical protein compare
BWI76_RS05810 +1.1 1.9 hypothetical protein compare
BWI76_RS19700 +1.1 2.4 deoxyribonuclease IV compare
BWI76_RS16455 +1.1 3.2 superoxide dismutase compare
BWI76_RS11635 +1.1 2.4 ABC transporter compare
BWI76_RS17935 +1.0 3.3 DUF2627 domain-containing protein compare
BWI76_RS17370 +1.0 1.9 nitrate transporter NasD compare
BWI76_RS25375 +1.0 3.0 hypothetical protein compare
BWI76_RS02580 +1.0 2.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS17930 +1.0 4.1 cold-shock protein CspC compare
BWI76_RS12595 +0.9 2.5 hypothetical protein compare
BWI76_RS01260 +0.9 6.7 lysophospholipase L2 compare
BWI76_RS07510 +0.9 3.0 hypothetical protein compare
BWI76_RS09610 +0.9 3.1 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS08825 +0.9 3.8 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS01195 +0.9 2.6 membrane protein compare
BWI76_RS19770 +0.9 2.3 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS00140 +0.9 1.1 phosphate transport system regulator PhoU compare
BWI76_RS09490 +0.9 2.2 DNA-binding response regulator compare
BWI76_RS13820 +0.9 2.2 hypothetical protein compare
BWI76_RS15980 +0.8 2.4 lysine transporter LysE compare
BWI76_RS24080 +0.8 1.8 DUF179 domain-containing protein compare
BWI76_RS04275 +0.8 4.1 molybdopterin adenylyltransferase compare
BWI76_RS10755 +0.8 1.5 pyrimidine utilization flavin reductase protein F compare
BWI76_RS01190 +0.8 2.5 iron donor protein CyaY compare
BWI76_RS16275 +0.8 2.6 fumarate hydratase FumA compare
BWI76_RS02225 +0.8 3.1 phosphonate C-P lyase system protein PhnG compare
BWI76_RS07075 +0.8 2.8 hypothetical protein compare
BWI76_RS27875 +0.8 0.9 membrane protein compare
BWI76_RS26095 +0.8 1.5 shikimate kinase compare
BWI76_RS20150 +0.8 2.4 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS12465 +0.8 1.2 phage shock protein D compare
BWI76_RS17795 +0.8 2.4 ribonuclease D compare
BWI76_RS06560 +0.8 2.5 7-cyano-7-deazaguanine synthase QueC compare
BWI76_RS12860 +0.8 1.6 hypothetical protein compare
BWI76_RS11445 +0.8 1.8 hypothetical protein compare
BWI76_RS21255 +0.8 3.2 hypothetical protein compare
BWI76_RS00865 +0.7 2.4 DNA-binding transcriptional regulator OxyR compare
BWI76_RS19145 +0.7 1.9 formate dehydrogenase cytochrome b556 subunit compare
BWI76_RS16160 +0.7 2.4 LysR family transcriptional regulator compare
BWI76_RS18335 +0.7 4.2 DNA-binding response regulator compare
BWI76_RS01585 +0.7 3.3 transcriptional regulator compare
BWI76_RS26245 +0.7 2.4 transcriptional regulator compare
BWI76_RS20165 +0.7 2.5 NADH-quinone oxidoreductase subunit G compare
BWI76_RS02800 +0.7 2.4 ABC transporter compare
BWI76_RS19460 +0.7 1.8 lipoprotein compare
BWI76_RS15195 +0.7 1.4 DUF4186 domain-containing protein compare
BWI76_RS09860 +0.7 2.2 hypothetical protein compare
BWI76_RS13135 +0.7 1.9 3-oxoadipyl-CoA thiolase compare
BWI76_RS20135 +0.7 3.5 NADH-quinone oxidoreductase subunit M compare
BWI76_RS22090 +0.7 2.0 transcriptional regulator compare
BWI76_RS11780 +0.7 1.8 2-deoxyglucose-6-phosphatase compare
BWI76_RS14735 +0.7 2.9 type 11 methyltransferase compare
BWI76_RS22625 +0.7 1.8 transcriptional regulator compare
BWI76_RS24065 +0.7 2.2 deoxyribonuclease I compare
BWI76_RS11150 +0.7 1.2 membrane protein compare
BWI76_RS20170 +0.7 2.6 NADH-quinone oxidoreductase subunit F compare
BWI76_RS05315 +0.7 2.3 Rho-binding antiterminator compare
BWI76_RS23050 +0.7 1.5 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS13470 +0.7 2.0 transporter compare
BWI76_RS24925 +0.7 1.5 DnaA initiator-associating protein DiaA compare
BWI76_RS17420 +0.7 3.2 hypothetical protein compare
BWI76_RS22815 +0.6 4.8 hybrid sensor histidine kinase/response regulator compare
BWI76_RS05360 +0.6 3.9 methionine ABC transporter permease compare
BWI76_RS11480 +0.6 4.3 hypothetical protein compare
BWI76_RS01095 +0.6 1.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS20785 +0.6 1.0 ethanolamine utilization protein EutJ compare
BWI76_RS10400 +0.6 1.7 hypothetical protein compare
BWI76_RS01200 +0.6 1.0 diaminopimelate epimerase compare
BWI76_RS08815 +0.6 4.5 cyclic pyranopterin phosphate synthase compare
BWI76_RS02310 +0.6 2.8 transcriptional regulator compare
BWI76_RS08820 +0.6 1.7 molybdenum cofactor biosynthesis protein compare
BWI76_RS24390 +0.6 3.0 hypothetical protein compare
BWI76_RS11895 +0.6 2.3 AraC family transcriptional regulator compare
BWI76_RS12515 +0.6 1.6 protease compare
BWI76_RS24945 +0.6 1.0 glutamine amidotransferase compare
BWI76_RS20230 +0.6 1.4 hypothetical protein compare
BWI76_RS00725 +0.6 2.2 periplasmic repressor CpxP compare
BWI76_RS04165 +0.6 2.3 DNA repair protein RadA compare
BWI76_RS16200 +0.6 1.4 NAD(P) transhydrogenase subunit beta compare
BWI76_RS22420 +0.6 1.8 LacI family transcriptional regulator compare
BWI76_RS26140 +0.6 1.6 GMP/IMP nucleotidase compare
BWI76_RS25905 +0.6 2.0 hypothetical protein compare
BWI76_RS12490 +0.6 2.8 AbrB family transcriptional regulator compare
BWI76_RS02090 +0.6 1.9 membrane protein compare
BWI76_RS22050 +0.6 1.4 class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI compare
BWI76_RS07460 +0.6 2.0 hypothetical protein compare
BWI76_RS18195 +0.6 2.6 tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB compare
BWI76_RS08650 +0.6 1.7 molybdate ABC transporter permease compare
BWI76_RS08980 +0.6 0.9 DNA starvation/stationary phase protection protein compare
BWI76_RS14755 +0.6 2.0 SIS domain-containing protein compare
BWI76_RS13170 +0.6 2.0 methyltransferase compare
BWI76_RS06465 +0.6 0.8 IclR family transcriptional regulator compare
BWI76_RS16000 +0.6 1.0 multidrug transporter subunit MdtI compare
BWI76_RS18605 +0.6 0.6 oxidoreductase molybdopterin-binding protein compare
BWI76_RS21810 +0.6 1.0 universal stress protein compare
BWI76_RS14030 +0.6 2.2 ABC transporter permease compare
BWI76_RS17350 +0.6 1.4 DNA-binding response regulator compare
BWI76_RS03045 +0.6 0.9 hypothetical protein compare
BWI76_RS09450 +0.6 1.7 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS02570 +0.6 3.5 transcriptional regulator compare
BWI76_RS22365 +0.6 2.8 hydrogenase expression/formation protein HypE compare
BWI76_RS07810 +0.6 1.9 sugar ABC transporter periplasmic sugar-binding protein compare
BWI76_RS06125 +0.6 2.8 D-alanine--D-alanine ligase A compare
BWI76_RS12270 +0.6 2.4 hypothetical protein compare
BWI76_RS24110 +0.6 1.6 YggU family protein compare
BWI76_RS17470 +0.6 2.2 MerR family transcriptional regulator compare
BWI76_RS14870 +0.6 1.2 hypothetical protein compare
BWI76_RS02745 +0.6 1.0 hypothetical protein compare
BWI76_RS06945 +0.6 2.0 multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1 compare
BWI76_RS14480 +0.6 3.4 hypothetical protein compare
BWI76_RS08620 +0.6 2.7 galactose-1-phosphate uridylyltransferase compare
BWI76_RS14000 +0.6 1.6 glutamine amidotransferase compare
BWI76_RS11060 +0.6 1.4 septum formation inhibitor Maf compare
BWI76_RS17400 +0.6 0.9 transporter compare
BWI76_RS23530 +0.6 1.8 MarR family transcriptional regulator compare
BWI76_RS17955 +0.6 1.7 hypothetical protein compare
BWI76_RS23860 +0.6 1.6 protein disulfide oxidoreductase compare
BWI76_RS16925 +0.6 2.4 3-(3-hydroxyphenyl)propionate hydroxylase compare
BWI76_RS13785 +0.6 0.9 ABC transporter permease compare
BWI76_RS14835 +0.5 1.0 hypothetical protein compare
BWI76_RS05480 +0.5 2.6 class II glutamine amidotransferase compare
BWI76_RS10430 +0.5 1.4 thiol:disulfide interchange protein DsbG compare
BWI76_RS04175 +0.5 1.8 energy-dependent translational throttle protein EttA compare
BWI76_RS23755 +0.5 1.9 transcriptional regulator compare
BWI76_RS00640 +0.5 1.4 L-rhamnose mutarotase compare
BWI76_RS19025 +0.5 3.7 phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating) compare
BWI76_RS15150 +0.5 1.5 outer membrane efflux protein compare
BWI76_RS06505 +0.5 2.3 hypothetical protein compare
BWI76_RS21375 +0.5 1.3 autonomous glycyl radical cofactor GrcA compare
BWI76_RS15365 +0.5 1.8 hypothetical protein compare
BWI76_RS14860 +0.5 3.4 ABC transporter compare
BWI76_RS18225 +0.5 2.1 universal stress protein C compare
BWI76_RS21850 +0.5 1.7 AraC family transcriptional regulator compare
BWI76_RS21495 +0.5 2.9 outer membrane lipoprotein compare
BWI76_RS00240 +0.5 0.9 FMN-binding protein MioC compare
BWI76_RS10730 +0.5 0.6 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS08025 +0.5 2.2 septal ring lytic transglycosylase RlpA compare
BWI76_RS27890 +0.5 1.8 GntR family transcriptional regulator compare
BWI76_RS20375 +0.5 0.7 membrane protein compare
BWI76_RS22935 +0.5 1.5 L-fucose mutarotase compare
BWI76_RS09305 +0.5 1.7 hypothetical protein compare
BWI76_RS13220 +0.5 2.3 N-acetyltransferase compare
BWI76_RS12225 +0.5 1.5 hypothetical protein compare
BWI76_RS14065 +0.5 0.8 hypothetical protein compare
BWI76_RS10035 +0.5 1.1 hypothetical protein compare
BWI76_RS13150 +0.5 1.5 carnitine operon protein CaiE compare
BWI76_RS27820 +0.5 1.0 ilvB operon leader peptide IvbL compare
BWI76_RS17570 +0.5 1.2 iron-sulfur-binding protein compare
BWI76_RS05365 +0.5 3.7 D-methionine ABC transporter, ATP-binding protein compare
BWI76_RS26015 +0.5 1.3 DUF2559 domain-containing protein compare
BWI76_RS06805 +0.5 1.7 primosomal replication protein N'' compare
BWI76_RS27850 +0.5 1.4 DNA-binding transcriptional regulator DsdC compare
BWI76_RS06870 +0.5 2.4 aminoacyl-tRNA deacylase compare
BWI76_RS07645 +0.5 1.4 short-chain dehydrogenase/reductase compare
BWI76_RS18175 +0.5 1.3 hydrolase compare
BWI76_RS19100 +0.5 2.3 putative acid phosphatase compare
BWI76_RS17620 +0.5 1.9 ABC transporter ATP-binding protein compare
BWI76_RS20280 +0.5 2.1 phosphodiesterase compare
BWI76_RS20930 +0.5 1.4 arsenate reductase (glutaredoxin) compare
BWI76_RS20140 +0.5 1.8 NADH-quinone oxidoreductase subunit L compare
BWI76_RS01905 +0.5 1.9 envelope stress response protein PspG compare
BWI76_RS19775 +0.5 1.2 phage resistance protein compare
BWI76_RS02820 +0.5 3.8 UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase compare
BWI76_RS08835 +0.5 2.8 molybdopterin guanine dinucleotide biosynthesis protein MoaE compare
BWI76_RS11675 +0.5 1.3 arginine N-succinyltransferase compare
BWI76_RS19515 +0.5 1.6 D-lactate dehydrogenase (cytochrome c-553) (EC 1.1.2.5) (from data) compare
BWI76_RS26130 +0.5 2.4 ADP compounds hydrolase NudE compare
BWI76_RS08510 +0.5 2.4 cyd operon protein YbgE compare
BWI76_RS27660 +0.5 2.1 hypothetical protein compare
BWI76_RS10745 +0.5 0.7 hypothetical protein compare
BWI76_RS10365 +0.5 1.6 class IV aminotransferase compare
BWI76_RS10585 +0.5 1.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS12585 +0.5 1.7 transcriptional regulator compare
BWI76_RS16230 +0.5 0.8 dihydromonapterin reductase compare
BWI76_RS23065 +0.5 2.1 cobalt-precorrin-6Y C(15)-methyltransferase compare
BWI76_RS16810 +0.5 1.6 RpiR family transcriptional regulator compare
BWI76_RS06190 +0.5 0.9 hypothetical protein compare
BWI76_RS08310 +0.5 1.4 potassium-transporting ATPase subunit C compare
BWI76_RS16400 +0.5 1.7 pyridoxal kinase compare
BWI76_RS21485 +0.5 2.8 DUF4154 domain-containing protein compare
BWI76_RS06060 +0.5 1.8 DNA-binding response regulator compare
BWI76_RS06290 +0.5 1.2 ACP phosphodiesterase compare
BWI76_RS22285 +0.5 2.7 transcriptional regulator compare
BWI76_RS21490 +0.5 3.3 GGDEF domain-containing protein compare
BWI76_RS23945 +0.5 2.2 methylmalonyl-CoA decarboxylase compare
BWI76_RS18575 +0.5 0.8 transcriptional regulator compare
BWI76_RS09555 +0.5 1.5 pyruvate oxidase compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Leucine in Klebsiella michiganensis M5al

For nitrogen source L-Leucine across organisms