Experiment set6IT053 for Klebsiella michiganensis M5al

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS01210 -8.0 -4.8 tyrosine recombinase XerC compare
BWI76_RS18920 -7.4 -5.1 ATP phosphoribosyltransferase compare
BWI76_RS08520 -7.2 -4.2 colicin transporter TolQ compare
BWI76_RS18950 -6.9 -4.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS04465 -6.4 -7.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS18930 -6.3 -4.6 histidinol-phosphate transaminase compare
BWI76_RS04470 -6.2 -12.7 carbamoyl phosphate synthase large subunit compare
BWI76_RS23360 -6.2 -4.1 diaminopimelate decarboxylase compare
BWI76_RS04160 -6.2 -7.2 phosphoserine phosphatase compare
BWI76_RS11965 -5.8 -4.3 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18925 -5.7 -6.4 histidinol dehydrogenase compare
BWI76_RS08385 -5.6 -4.7 citrate (Si)-synthase compare
BWI76_RS18935 -5.5 -7.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS20355 -5.4 -3.1 colicin V production protein compare
BWI76_RS09755 -5.4 -10.4 phosphoserine transaminase compare
BWI76_RS17720 -5.4 -1.9 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS09645 -5.3 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS02995 -5.2 -10.3 aspartate carbamoyltransferase compare
BWI76_RS00390 -5.2 -8.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS08180 -5.1 -8.9 asparagine synthase B compare
BWI76_RS00385 -5.1 -11.0 nitrogen assimilation regulatory protein compare
BWI76_RS00965 -5.1 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS23240 -4.9 -3.4 exonuclease V subunit gamma compare
BWI76_RS00855 -4.8 -8.9 argininosuccinate lyase compare
BWI76_RS23920 -4.6 -7.8 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS11845 -4.6 -2.5 tryptophan synthase subunit beta compare
BWI76_RS05835 -4.5 -3.7 gamma-glutamyl-phosphate reductase compare
BWI76_RS20965 -4.5 -4.9 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS20350 -4.4 -5.9 amidophosphoribosyltransferase compare
BWI76_RS06530 -4.4 -8.5 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS25115 -4.3 -7.2 argininosuccinate synthase compare
BWI76_RS09910 -4.3 -15.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS01615 -4.3 -10.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS09660 -4.2 -2.9 DNA translocase FtsK compare
BWI76_RS04685 -4.1 -12.8 putative leucine operon leader peptide compare
BWI76_RS04675 -4.0 -6.4 3-isopropylmalate dehydrogenase compare
BWI76_RS01610 -4.0 -5.7 phosphoribosylamine--glycine ligase compare
BWI76_RS23230 -4.0 -4.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS11840 -3.9 -6.8 tryptophan synthase subunit alpha compare
BWI76_RS10990 -3.9 -4.5 dihydroorotase compare
BWI76_RS04670 -3.9 -9.9 3-isopropylmalate dehydratase large subunit compare
BWI76_RS21265 -3.7 -11.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18940 -3.7 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS08525 -3.7 -4.8 colicin transporter compare
BWI76_RS26085 -3.7 -2.9 3-dehydroquinate synthase compare
BWI76_RS00990 -3.6 -10.2 ketol-acid reductoisomerase compare
BWI76_RS00400 -3.6 -2.9 glutamine synthetase compare
BWI76_RS22755 -3.5 -7.9 phosphoadenosine phosphosulfate reductase compare
BWI76_RS06525 -3.4 -5.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS27385 -3.4 -6.4 orotate phosphoribosyltransferase compare
BWI76_RS00345 -3.4 -5.5 protein disulfide oxidoreductase DsbA compare
BWI76_RS00975 -3.3 -9.3 dihydroxy-acid dehydratase compare
BWI76_RS05200 -3.3 -3.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS09760 -3.3 -7.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS22690 -3.3 -3.2 adenylyl-sulfate kinase compare
BWI76_RS20895 -3.2 -4.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04680 -3.1 -9.2 2-isopropylmalate synthase compare
BWI76_RS04665 -3.1 -17.3 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09970 -3.1 -5.5 porin OmpA compare
BWI76_RS23265 -3.0 -4.6 hypothetical protein compare
BWI76_RS05840 -2.9 -4.0 glutamate 5-kinase compare
BWI76_RS08530 -2.8 -2.7 protein TolA compare
BWI76_RS11850 -2.8 -5.6 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS17975 -2.8 -6.2 tail-specific protease compare
BWI76_RS07070 -2.7 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS16965 -2.6 -5.7 murein lipoprotein compare
BWI76_RS08535 -2.6 -1.6 translocation protein TolB compare
BWI76_RS00835 -2.5 -9.2 phosphoenolpyruvate carboxylase compare
BWI76_RS18630 -2.5 -6.8 nitrogen assimilation transcriptional regulator compare
BWI76_RS21075 -2.4 -2.4 membrane protein compare
BWI76_RS17980 -2.4 -3.5 RNA chaperone ProQ compare
BWI76_RS04305 -2.4 -1.6 molecular chaperone DnaJ compare
BWI76_RS01350 -2.4 -1.4 NAD(P)H-flavin reductase compare
BWI76_RS27430 -2.3 -1.6 (p)ppGpp synthetase compare
BWI76_RS05015 -2.3 -2.8 transcriptional regulator compare
BWI76_RS02530 -2.3 -2.3 tRNA dimethylallyltransferase compare
BWI76_RS15825 -2.3 -2.8 hypothetical protein compare
BWI76_RS23480 -2.3 -10.0 EAL domain-containing protein compare
BWI76_RS07065 -2.2 -7.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04645 -2.2 -6.6 3-dehydroquinase compare
BWI76_RS12145 -2.2 -2.5 hypothetical protein compare
BWI76_RS27390 -2.2 -3.5 ribonuclease PH compare
BWI76_RS18605 -2.2 -2.2 oxidoreductase molybdopterin-binding protein compare
BWI76_RS17735 -2.2 -5.7 D-amino acid dehydrogenase small subunit compare
BWI76_RS19840 -2.2 -1.6 hypothetical protein compare
BWI76_RS06535 -2.1 -4.3 endopeptidase La compare
BWI76_RS22765 -2.1 -7.9 sulfite reductase subunit alpha compare
BWI76_RS27440 -2.0 -4.0 DNA helicase RecG compare
BWI76_RS22805 -2.0 -8.5 GTP diphosphokinase compare
BWI76_RS03010 -2.0 -6.0 ornithine carbamoyltransferase compare
BWI76_RS25280 -2.0 -2.1 RNase adaptor protein RapZ compare
BWI76_RS17345 -2.0 -3.5 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS04060 -2.0 -1.6 hypothetical protein compare
BWI76_RS19010 -1.9 -4.2 polysaccharide pyruvyl transferase yvff compare
BWI76_RS11855 -1.9 -4.4 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS21370 -1.9 -1.4 ATP-dependent RNA helicase SrmB compare
BWI76_RS15835 -1.8 -1.2 hypothetical protein compare
BWI76_RS21565 -1.8 -1.5 outer membrane protein assembly factor BamE compare
BWI76_RS00960 -1.8 -3.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS26570 -1.8 -2.5 anion permease compare
BWI76_RS18715 -1.8 -5.7 hypothetical protein compare
BWI76_RS04255 -1.8 -4.9 threonine synthase compare
BWI76_RS19845 -1.8 -4.3 phosphatase compare
BWI76_RS06765 -1.7 -3.5 transcriptional regulator compare
BWI76_RS00970 -1.7 -2.7 branched chain amino acid aminotransferase compare
BWI76_RS25065 -1.7 -3.0 polyribonucleotide nucleotidyltransferase compare
BWI76_RS18165 -1.7 -2.0 NUDIX pyrophosphatase compare
BWI76_RS20435 -1.7 -1.4 chorismate synthase compare
BWI76_RS19330 -1.7 -1.4 HAD family hydrolase compare
BWI76_RS04715 -1.7 -2.6 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS26460 -1.6 -5.0 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS00785 -1.6 -4.5 cystathionine gamma-synthase compare
BWI76_RS05120 -1.6 -6.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS11860 -1.6 -4.3 anthranilate synthase component I compare
BWI76_RS07725 -1.6 -1.5 iron-enterobactin transporter permease compare
BWI76_RS01630 -1.6 -1.2 16S ribosomal RNA compare
BWI76_RS26455 -1.6 -4.4 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS14410 -1.6 -2.6 hypothetical protein compare
BWI76_RS03105 -1.5 -1.2 myo-inosose-2 dehydratase compare
BWI76_RS02410 -1.5 -1.6 EF-P beta-lysylation protein EpmB compare
BWI76_RS17525 -1.5 -1.7 XshC-Cox1-family protein compare
BWI76_RS14915 -1.5 -3.1 hypothetical protein compare
BWI76_RS22760 -1.5 -3.6 sulfite reductase subunit beta compare
BWI76_RS02545 -1.5 -5.1 protease modulator HflK compare
BWI76_RS01655 -1.5 -4.5 homoserine O-succinyltransferase compare
BWI76_RS05990 -1.5 -4.6 branched-chain amino acid ABC transporter permease compare
BWI76_RS15845 -1.4 -1.2 hypothetical protein compare
BWI76_RS11300 -1.4 -1.2 cupin compare
BWI76_RS00875 -1.4 -5.4 DNA-binding transcriptional regulator FabR compare
BWI76_RS06475 -1.4 -1.6 protoheme IX farnesyltransferase compare
BWI76_RS19495 -1.4 -1.2 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS23365 -1.4 -2.8 LysR family transcriptional regulator compare
BWI76_RS24100 -1.4 -2.9 YggS family pyridoxal phosphate enzyme compare
BWI76_RS20640 -1.4 -3.0 cysteine synthase A compare
BWI76_RS24340 -1.4 -5.0 two-component sensor histidine kinase compare
BWI76_RS05985 -1.3 -3.7 branched-chain amino acid ABC transporter permease compare
BWI76_RS18955 -1.3 -2.5 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS25920 -1.3 -1.5 peptidylprolyl isomerase compare
BWI76_RS16955 -1.3 -1.0 hypothetical protein compare
BWI76_RS17045 -1.3 -1.6 hypothetical protein compare
BWI76_RS26395 -1.3 -3.5 cell division protein FtsE compare
BWI76_RS11260 -1.3 -2.0 hypothetical protein compare
BWI76_RS21465 -1.3 -3.2 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS21475 -1.3 -3.7 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS20205 -1.3 -3.2 aminotransferase AlaT compare
BWI76_RS25910 -1.3 -2.6 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS26830 -1.2 -5.8 endoglucanase compare
BWI76_RS18770 -1.2 -1.1 DNA gyrase inhibitor compare
BWI76_RS11700 -1.2 -1.4 hypothetical protein compare
BWI76_RS06540 -1.2 -3.0 DNA-binding protein HU-beta compare
BWI76_RS04250 -1.2 -4.4 homoserine kinase compare
BWI76_RS00715 -1.2 -2.6 two-component sensor histidine kinase compare
BWI76_RS02550 -1.2 -4.1 protease modulator HflC compare
BWI76_RS05975 -1.2 -4.5 ABC transporter ATP-binding protein compare
BWI76_RS01115 -1.2 -1.8 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS00805 -1.2 -2.0 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS21070 -1.2 -1.7 outer membrane protein assembly factor BamB compare
BWI76_RS18710 -1.2 -7.2 GGDEF-domain containing protein compare
BWI76_RS09030 -1.2 -5.9 transpeptidase compare
BWI76_RS05980 -1.2 -5.4 ABC transporter ATP-binding protein compare
BWI76_RS13595 -1.2 -3.1 transcriptional regulator compare
BWI76_RS23970 -1.2 -1.8 mechanosensitive ion channel protein MscS compare
BWI76_RS12390 -1.2 -1.8 antibiotic biosynthesis monooxygenase compare
BWI76_RS06800 -1.2 -1.2 DUF2496 domain-containing protein compare
BWI76_RS12590 -1.2 -2.9 helix-turn-helix-type transcriptional regulator compare
BWI76_RS01070 -1.1 -4.7 thiol reductase thioredoxin compare
BWI76_RS26390 -1.1 -3.6 cell division protein FtsX compare
BWI76_RS05915 -1.1 -1.9 helix-turn-helix transcriptional regulator compare
BWI76_RS26055 -1.1 -4.7 siroheme synthase compare
BWI76_RS25960 -1.1 -2.2 NUDIX hydrolase compare
BWI76_RS19325 -1.1 -1.6 mandelate racemase compare
BWI76_RS19685 -1.1 -4.4 lysine transporter compare
BWI76_RS15810 -1.1 -3.0 hypothetical protein compare
BWI76_RS00575 -1.1 -5.6 DNA-binding protein compare
BWI76_RS00790 -1.1 -4.1 bifunctional aspartokinase II/homoserine dehydrogenase II compare
BWI76_RS13330 -1.1 -1.5 tellurite resistance methyltransferase TehB compare
BWI76_RS26775 -1.1 -4.4 endo-1,4-D-glucanase compare
BWI76_RS06485 -1.0 -2.2 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS06770 -1.0 -5.2 Hha toxicity attenuator compare
BWI76_RS26405 -1.0 -1.3 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS15840 -1.0 -1.9 prophage protein compare
BWI76_RS08210 -1.0 -1.9 N-acetylglucosamine-6-phosphate deacetylase compare
BWI76_RS16190 -1.0 -3.4 universal stress protein UspE compare
BWI76_RS13480 -1.0 -1.4 XRE family transcriptional regulator compare
BWI76_RS11285 -1.0 -1.4 transcriptional regulator compare
BWI76_RS22640 -1.0 -1.6 hypothetical protein compare
BWI76_RS24285 -1.0 -4.7 cystathionine beta-lyase compare
BWI76_RS13600 -1.0 -1.9 hypothetical protein compare
BWI76_RS11675 -1.0 -1.5 arginine N-succinyltransferase compare
BWI76_RS14415 -1.0 -1.3 transcriptional regulator, TetR family protein compare
BWI76_RS00025 -1.0 -0.7 hypothetical protein compare
BWI76_RS08925 -1.0 -3.4 DNA-binding protein YbiB compare
BWI76_RS12090 -1.0 -1.0 HNH endonuclease compare
BWI76_RS25300 -1.0 -2.2 hybrid sensor histidine kinase/response regulator compare
BWI76_RS00430 -1.0 -3.0 GNAT family N-acetyltransferase compare
BWI76_RS25600 -1.0 -1.0 tRNA-Thr compare
BWI76_RS15620 -0.9 -1.7 hypothetical protein compare
BWI76_RS13820 -0.9 -1.0 hypothetical protein compare
BWI76_RS06080 -0.9 -2.4 taurine dioxygenase compare
BWI76_RS01885 -0.9 -1.0 CsbD family protein compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Isoleucine in Klebsiella michiganensis M5al

For nitrogen source L-Isoleucine across organisms