Experiment set6IT053 for Klebsiella michiganensis M5al

Compare to:

L-Isoleucine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS25425 +2.0 5.9 arginine repressor compare
BWI76_RS20995 +1.8 7.3 RNA degradosome polyphosphate kinase compare
BWI76_RS09655 +1.7 7.5 leucine-responsive regulatory protein compare
BWI76_RS09650 +1.7 8.3 hypothetical protein compare
BWI76_RS24575 +1.5 3.2 hypothetical protein compare
BWI76_RS08650 +1.2 3.8 molybdate ABC transporter permease compare
BWI76_RS08825 +1.2 4.7 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS19770 +1.2 3.1 bifunctional murein DD-endopeptidase/murein LD-carboxypeptidase compare
BWI76_RS09085 +1.2 6.2 molybdopterin molybdenumtransferase MoeA compare
BWI76_RS14065 +1.2 1.6 hypothetical protein compare
BWI76_RS20910 +1.2 4.7 glycine cleavage system transcriptional repressor compare
BWI76_RS08815 +1.2 8.4 cyclic pyranopterin phosphate synthase compare
BWI76_RS17375 +1.2 2.8 nitrate ABC transporter, permease protein compare
BWI76_RS09080 +1.1 4.2 molybdopterin-synthase adenylyltransferase MoeB compare
BWI76_RS07740 +1.1 2.5 Fe2+-enterobactin ABC transporter substrate-binding protein compare
BWI76_RS09625 +1.1 1.9 hypothetical protein compare
BWI76_RS04275 +1.1 5.7 molybdopterin adenylyltransferase compare
BWI76_RS17370 +1.1 3.0 nitrate transporter NasD compare
BWI76_RS16230 +1.1 3.0 dihydromonapterin reductase compare
BWI76_RS02580 +1.0 1.3 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS17155 +1.0 2.3 hypothetical protein compare
BWI76_RS16455 +1.0 2.3 superoxide dismutase compare
BWI76_RS01325 +1.0 2.6 twin-arginine translocase subunit TatB compare
BWI76_RS12420 +1.0 1.5 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS11820 +1.0 1.4 short-chain dehydrogenase/reductase SDR compare
BWI76_RS11460 +0.9 3.0 DUF441 family protein compare
BWI76_RS12040 +0.9 1.6 hypothetical protein compare
BWI76_RS09610 +0.9 2.4 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS03665 +0.9 1.3 ABC transporter ATP-binding protein compare
BWI76_RS00330 +0.9 5.3 molybdenum cofactor guanylyltransferase compare
BWI76_RS16355 +0.9 2.1 electron transport complex subunit A compare
BWI76_RS27820 +0.9 1.5 ilvB operon leader peptide IvbL compare
BWI76_RS11235 +0.9 1.3 hypothetical protein compare
BWI76_RS05810 +0.9 1.3 hypothetical protein compare
BWI76_RS08835 +0.9 4.9 molybdopterin guanine dinucleotide biosynthesis protein MoaE compare
BWI76_RS05965 +0.9 2.2 hypothetical protein compare
BWI76_RS05570 +0.9 1.3 hypothetical protein compare
BWI76_RS21140 +0.9 2.0 molecular chaperone HscA compare
BWI76_RS07185 +0.8 1.0 hypothetical protein compare
BWI76_RS12465 +0.8 1.3 phage shock protein D compare
BWI76_RS24180 +0.8 2.0 hypothetical protein compare
BWI76_RS09615 +0.8 1.4 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS23895 +0.8 1.3 Xaa-Pro aminopeptidase compare
BWI76_RS06340 +0.8 1.1 hypothetical protein compare
BWI76_RS00180 +0.8 0.8 F0F1 ATP synthase subunit epsilon compare
BWI76_RS17380 +0.8 4.2 nitrate transporter component compare
BWI76_RS21560 +0.8 2.2 DNA repair protein RecN compare
BWI76_RS17385 +0.8 5.8 nitrate regulatory protein compare
BWI76_RS19195 +0.8 2.4 nickel ABC transporter permease compare
BWI76_RS04815 +0.8 1.6 cell division protein ZapD compare
BWI76_RS23140 +0.8 1.9 carboxysome shell protein compare
BWI76_RS11060 +0.8 1.9 septum formation inhibitor Maf compare
BWI76_RS12700 +0.8 2.4 hypothetical protein compare
BWI76_RS01815 +0.8 3.4 phosphate-starvation-inducible protein PsiE compare
BWI76_RS26140 +0.8 2.7 GMP/IMP nucleotidase compare
BWI76_RS20155 +0.8 1.1 NADH-quinone oxidoreductase subunit I compare
BWI76_RS10635 +0.8 3.2 GGDEF domain-containing protein compare
BWI76_RS12595 +0.8 3.2 hypothetical protein compare
BWI76_RS10500 +0.8 1.9 flavoprotein monooxygenase compare
BWI76_RS01330 +0.8 1.6 twin-arginine translocase subunit TatC compare
BWI76_RS18885 +0.8 1.3 nitrogen fixation regulatory protein compare
BWI76_RS03595 +0.8 0.9 ethanolamine utilization protein EutM compare
BWI76_RS07640 +0.8 1.2 short chain dehydrogenase compare
BWI76_RS21345 +0.8 2.5 sigma-E factor regulatory protein RseB compare
BWI76_RS26065 +0.7 2.9 phosphoglycolate phosphatase compare
BWI76_RS20150 +0.7 1.9 NADH:ubiquinone oxidoreductase subunit J compare
BWI76_RS23320 +0.7 1.2 hypothetical protein compare
BWI76_RS05425 +0.7 2.5 EEP domain-containing protein compare
BWI76_RS15095 +0.7 2.0 isochorismatase compare
BWI76_RS11610 +0.7 1.5 glutamate dehydrogenase compare
BWI76_RS19860 +0.7 1.3 hypothetical protein compare
BWI76_RS04515 +0.7 1.3 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS00865 +0.7 2.7 DNA-binding transcriptional regulator OxyR compare
BWI76_RS00240 +0.7 1.7 FMN-binding protein MioC compare
BWI76_RS00060 +0.7 1.7 N-acetylneuraminate lyase compare
BWI76_RS10575 +0.7 1.3 polar amino acid ABC transporter permease compare
BWI76_RS00140 +0.7 0.8 phosphate transport system regulator PhoU compare
BWI76_RS19705 +0.7 1.9 kinase compare
BWI76_RS24740 +0.7 2.6 GntR family transcriptional regulator compare
BWI76_RS07710 +0.7 1.2 invasin-like protein compare
BWI76_RS06125 +0.7 3.2 D-alanine--D-alanine ligase A compare
BWI76_RS00065 +0.7 2.7 MurR/RpiR family transcriptional regulator compare
BWI76_RS01195 +0.7 1.6 membrane protein compare
BWI76_RS12855 +0.7 1.3 enamine deaminase RidA compare
BWI76_RS12050 +0.7 1.7 hypothetical protein compare
BWI76_RS20885 +0.7 2.5 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS15240 +0.7 3.5 alcohol dehydrogenase compare
BWI76_RS16170 +0.7 2.5 amidohydrolase compare
BWI76_RS02570 +0.7 4.4 transcriptional regulator compare
BWI76_RS00880 +0.7 3.6 membrane protein compare
BWI76_RS19695 +0.7 1.8 membrane protein compare
BWI76_RS21165 +0.7 1.4 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS06405 +0.7 1.8 2-dehydropantoate 2-reductase compare
BWI76_RS08820 +0.7 1.9 molybdenum cofactor biosynthesis protein compare
BWI76_RS26875 +0.7 2.0 dipeptide ABC transporter permease DppC compare
BWI76_RS07475 +0.7 1.0 DNA-binding transcriptional regulator RamA compare
BWI76_RS04510 +0.7 1.8 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS00080 +0.7 2.2 N-acetylmannosamine kinase compare
BWI76_RS21460 +0.7 1.1 translation inhibitor protein RaiA compare
BWI76_RS14735 +0.7 3.0 type 11 methyltransferase compare
BWI76_RS21675 +0.7 1.1 hypothetical protein compare
BWI76_RS24720 +0.7 0.8 hypothetical protein compare
BWI76_RS16335 +0.7 1.2 division septum protein Blr compare
BWI76_RS26245 +0.7 2.3 transcriptional regulator compare
BWI76_RS09135 +0.7 2.1 oxidoreductase compare
BWI76_RS14845 +0.6 1.3 hypothetical protein compare
BWI76_RS07325 +0.6 2.5 aminoimidazole riboside kinase compare
BWI76_RS08395 +0.6 1.7 succinate dehydrogenase cytochrome b556 large subunit compare
BWI76_RS13645 +0.6 1.6 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS20805 +0.6 1.3 phosphate acetyltransferase compare
BWI76_RS01585 +0.6 3.4 transcriptional regulator compare
BWI76_RS13630 +0.6 2.1 ABC transporter compare
BWI76_RS13175 +0.6 2.9 NodT family RND efflux system outer membrane lipoprotein compare
BWI76_RS02090 +0.6 0.9 membrane protein compare
BWI76_RS11335 +0.6 1.0 tautomerase compare
BWI76_RS27850 +0.6 2.0 DNA-binding transcriptional regulator DsdC compare
BWI76_RS17945 +0.6 1.2 hypothetical protein compare
BWI76_RS26605 +0.6 3.4 16S rRNA (guanine(1516)-N(2))-methyltransferase compare
BWI76_RS11200 +0.6 2.2 transpeptidase compare
BWI76_RS16500 +0.6 1.1 superoxide dismutase [Fe] compare
BWI76_RS11110 +0.6 2.1 cell division protein YceG compare
BWI76_RS14835 +0.6 1.1 hypothetical protein compare
BWI76_RS02745 +0.6 1.0 hypothetical protein compare
BWI76_RS00720 +0.6 1.7 DNA-binding response regulator compare
BWI76_RS10700 +0.6 1.0 XRE family transcriptional regulator compare
BWI76_RS19460 +0.6 1.5 lipoprotein compare
BWI76_RS16360 +0.6 1.0 electron transport complex subunit RsxB compare
BWI76_RS22350 +0.6 1.9 hydrogenase nickel incorporation protein HypB compare
BWI76_RS08425 +0.6 2.9 succinyl-CoA ligase subunit beta compare
BWI76_RS16330 +0.6 1.5 oxidoreductase compare
BWI76_RS25320 +0.6 3.5 glutamate synthase compare
BWI76_RS21255 +0.6 2.6 hypothetical protein compare
BWI76_RS27015 +0.6 2.2 hypothetical protein compare
BWI76_RS11810 +0.6 1.6 outer membrane protein OmpW compare
BWI76_RS13240 +0.6 0.9 hypothetical protein compare
BWI76_RS15295 +0.6 2.6 MDR efflux pump AcrAB transcriptional activator MarA compare
BWI76_RS12820 +0.6 2.7 NAD-dependent phenylacetaldehyde dehydrogenase compare
BWI76_RS22365 +0.6 2.4 hydrogenase expression/formation protein HypE compare
BWI76_RS00095 +0.6 1.6 DNA-binding transcriptional regulator compare
BWI76_RS10740 +0.6 1.8 NAD(P)H:quinone oxidoreductase compare
BWI76_RS18270 +0.6 1.5 hypothetical protein compare
BWI76_RS16075 +0.6 1.0 oxidoreductase compare
BWI76_RS04955 +0.6 1.0 hypoxanthine phosphoribosyltransferase compare
BWI76_RS08280 +0.6 1.1 acyl-CoA esterase compare
BWI76_RS11970 +0.6 1.9 stress response translation initiation inhibitor YciH compare
BWI76_RS27610 +0.6 1.9 hydroxyacid dehydrogenase compare
BWI76_RS06295 +0.6 1.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS03165 +0.6 2.7 phage polarity suppression protein compare
BWI76_RS03285 +0.6 1.7 hypothetical protein compare
BWI76_RS14775 +0.6 1.1 creatinine amidohydrolase compare
BWI76_RS19700 +0.6 1.0 deoxyribonuclease IV compare
BWI76_RS27200 +0.6 2.3 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL compare
BWI76_RS07905 +0.6 2.9 trimethylamine-N-oxide reductase (cytochrome c) compare
BWI76_RS03180 +0.6 0.8 phage transcriptional regulator, AlpA compare
BWI76_RS02210 +0.6 2.5 carbon-phosphorus lyase complex subunit PhnJ compare
BWI76_RS16810 +0.6 3.0 RpiR family transcriptional regulator compare
BWI76_RS16205 +0.5 1.9 NAD(P) transhydrogenase subunit alpha compare
BWI76_RS21490 +0.5 3.2 GGDEF domain-containing protein compare
BWI76_RS24255 +0.5 1.4 thiol:disulfide oxidoreductase compare
BWI76_RS20810 +0.5 1.9 ethanolamine utilization cobalamin adenosyltransferase compare
BWI76_RS14840 +0.5 1.4 hypothetical protein compare
BWI76_RS13770 +0.5 2.1 alkylhydroperoxidase domain protein compare
BWI76_RS02310 +0.5 3.0 transcriptional regulator compare
BWI76_RS13300 +0.5 2.3 carboxylesterase compare
BWI76_RS13990 +0.5 2.2 allophanate hydrolase compare
BWI76_RS02800 +0.5 2.0 ABC transporter compare
BWI76_RS06895 +0.5 3.1 biopolymer transporter ExbB compare
BWI76_RS26850 +0.5 3.0 cellulose synthase catalytic subunit (UDP-forming) compare
BWI76_RS01260 +0.5 3.3 lysophospholipase L2 compare
BWI76_RS21290 +0.5 1.8 DNA-binding transcriptional regulator compare
BWI76_RS24110 +0.5 0.8 YggU family protein compare
BWI76_RS23530 +0.5 1.7 MarR family transcriptional regulator compare
BWI76_RS25000 +0.5 0.8 malonate decarboxylase acyl carrier protein compare
BWI76_RS11440 +0.5 0.8 hypothetical protein compare
BWI76_RS26840 +0.5 4.0 cellulose synthase compare
BWI76_RS15945 +0.5 2.2 voltage-gated ClC-type chloride channel ClcB compare
BWI76_RS05335 +0.5 1.9 copper homeostasis/adhesion lipoprotein NlpE compare
BWI76_RS21410 +0.5 1.2 lipoprotein compare
BWI76_RS07200 +0.5 1.7 MFS transporter compare
BWI76_RS06400 +0.5 1.0 oxidative-stress-resistance chaperone compare
BWI76_RS15980 +0.5 1.2 lysine transporter LysE compare
BWI76_RS24765 +0.5 0.8 membrane protein compare
BWI76_RS08750 +0.5 0.8 kinase inhibitor compare
BWI76_RS24975 +0.5 2.6 U32 family peptidase compare
BWI76_RS08360 +0.5 1.0 LamB/YcsF family protein compare
BWI76_RS09560 +0.5 1.0 DoxX family membrane protein compare
BWI76_RS07510 +0.5 1.1 hypothetical protein compare
BWI76_RS06240 +0.5 2.1 branched-chain amino acid transport system 2 carrier protein BrnQ compare
BWI76_RS11895 +0.5 1.0 AraC family transcriptional regulator compare
BWI76_RS22960 +0.5 1.3 YgdI/YgdR family lipoprotein compare
BWI76_RS22625 +0.5 1.2 transcriptional regulator compare
BWI76_RS21780 +0.5 1.4 S-(hydroxymethyl)glutathione synthase compare
BWI76_RS16015 +0.5 1.6 pheromone autoinducer 2 transporter compare
BWI76_RS19730 +0.5 1.8 1-phosphofructokinase compare
BWI76_RS24795 +0.5 2.6 hypothetical protein compare
BWI76_RS19220 +0.5 1.4 hypothetical protein compare
BWI76_RS11915 +0.5 1.8 protease SohB compare
BWI76_RS00985 +0.5 2.3 transcriptional regulator IlvY compare
BWI76_RS25375 +0.5 1.1 hypothetical protein compare
BWI76_RS23810 +0.5 1.2 bifunctional protein-disulfide isomerase/oxidoreductase DsbC compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Isoleucine in Klebsiella michiganensis M5al

For nitrogen source L-Isoleucine across organisms