Experiment set6IT046 for Klebsiella michiganensis M5al

Compare to:

L-Asparagine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20965 -9.0 -4.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS20355 -8.9 -4.8 colicin V production protein compare
BWI76_RS11965 -8.5 -5.2 orotidine-5'-phosphate decarboxylase compare
BWI76_RS04250 -8.3 -5.7 homoserine kinase compare
BWI76_RS18925 -7.9 -4.8 histidinol dehydrogenase compare
BWI76_RS04255 -7.7 -5.3 threonine synthase compare
BWI76_RS04160 -7.5 -7.1 phosphoserine phosphatase compare
BWI76_RS25115 -7.5 -7.3 argininosuccinate synthase compare
BWI76_RS24285 -7.4 -7.2 cystathionine beta-lyase compare
BWI76_RS20350 -7.3 -6.7 amidophosphoribosyltransferase compare
BWI76_RS18920 -7.3 -4.5 ATP phosphoribosyltransferase compare
BWI76_RS18940 -7.3 -4.7 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS07070 -7.2 -5.0 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00805 -7.2 -5.5 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS27385 -7.1 -4.9 orotate phosphoribosyltransferase compare
BWI76_RS18950 -7.1 -5.7 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00990 -7.0 -8.3 ketol-acid reductoisomerase compare
BWI76_RS00850 -7.0 -9.7 acetylglutamate kinase compare
BWI76_RS09755 -7.0 -6.8 phosphoserine transaminase compare
BWI76_RS18955 -6.9 -5.9 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS01655 -6.8 -8.4 homoserine O-succinyltransferase compare
BWI76_RS05840 -6.8 -4.7 glutamate 5-kinase compare
BWI76_RS11850 -6.8 -8.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00855 -6.7 -8.0 argininosuccinate lyase compare
BWI76_RS23920 -6.7 -5.6 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04675 -6.7 -5.8 3-isopropylmalate dehydrogenase compare
BWI76_RS21475 -6.6 -5.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS04470 -6.6 -11.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS08385 -6.5 -3.2 citrate (Si)-synthase compare
BWI76_RS18935 -6.5 -8.0 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS11860 -6.5 -8.8 anthranilate synthase component I compare
BWI76_RS04680 -6.4 -13.0 2-isopropylmalate synthase compare
BWI76_RS20895 -6.4 -6.0 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04465 -6.3 -5.3 carbamoyl-phosphate synthase small subunit compare
BWI76_RS04245 -6.3 -13.5 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS04665 -6.3 -19.5 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04685 -6.3 -8.7 putative leucine operon leader peptide compare
BWI76_RS00980 -6.3 -11.4 PLP-dependent threonine dehydratase compare
BWI76_RS21265 -6.2 -12.7 phosphoribosylformylglycinamidine synthase compare
BWI76_RS23360 -6.1 -3.6 diaminopimelate decarboxylase compare
BWI76_RS04670 -6.0 -9.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS02995 -5.7 -8.1 aspartate carbamoyltransferase compare
BWI76_RS23220 -5.7 -7.5 amino-acid N-acetyltransferase compare
BWI76_RS05835 -5.6 -4.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS01615 -5.6 -8.2 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS22690 -5.5 -3.6 adenylyl-sulfate kinase compare
BWI76_RS00975 -5.5 -10.3 dihydroxy-acid dehydratase compare
BWI76_RS00785 -5.5 -7.3 cystathionine gamma-synthase compare
BWI76_RS11840 -5.4 -3.7 tryptophan synthase subunit alpha compare
BWI76_RS20380 -5.4 -1.7 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS21465 -5.4 -4.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS22755 -5.4 -8.8 phosphoadenosine phosphosulfate reductase compare
BWI76_RS22805 -5.4 -13.3 GTP diphosphokinase compare
BWI76_RS09760 -5.2 -3.7 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00845 -5.2 -9.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS07065 -5.1 -7.0 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS18930 -5.1 -3.5 histidinol-phosphate transaminase compare
BWI76_RS00965 -5.1 -1.6 acetolactate synthase 2 small subunit compare
BWI76_RS03010 -5.0 -7.2 ornithine carbamoyltransferase compare
BWI76_RS04645 -5.0 -4.8 3-dehydroquinase compare
BWI76_RS22760 -5.0 -9.5 sulfite reductase subunit beta compare
BWI76_RS00400 -4.9 -2.6 glutamine synthetase compare
BWI76_RS01610 -4.8 -6.2 phosphoribosylamine--glycine ligase compare
BWI76_RS09910 -4.8 -13.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS22765 -4.8 -10.4 sulfite reductase subunit alpha compare
BWI76_RS23240 -4.8 -3.3 exonuclease V subunit gamma compare
BWI76_RS23365 -4.6 -5.3 LysR family transcriptional regulator compare
BWI76_RS11845 -4.6 -2.3 tryptophan synthase subunit beta compare
BWI76_RS10990 -4.6 -3.4 dihydroorotase compare
BWI76_RS20640 -4.5 -4.4 cysteine synthase A compare
BWI76_RS00985 -4.5 -8.2 transcriptional regulator IlvY compare
BWI76_RS23230 -4.4 -3.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS05200 -4.3 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS26085 -4.3 -2.9 3-dehydroquinate synthase compare
BWI76_RS09660 -4.1 -2.8 DNA translocase FtsK compare
BWI76_RS26000 -4.1 -6.4 aspartate aminotransferase family protein compare
BWI76_RS27390 -4.1 -3.2 ribonuclease PH compare
BWI76_RS02735 -4.1 -5.9 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS11855 -3.8 -5.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS25645 -3.6 -5.5 shikimate dehydrogenase compare
BWI76_RS26055 -3.5 -7.1 siroheme synthase compare
BWI76_RS11580 -3.3 -2.8 L-asparaginase 1 compare
BWI76_RS25320 -3.2 -4.8 glutamate synthase compare
BWI76_RS25315 -3.1 -8.6 glutamate synthase large subunit compare
BWI76_RS11335 -3.0 -1.6 tautomerase compare
BWI76_RS04240 -3.0 -1.6 thr operon leader peptide compare
BWI76_RS20435 -2.9 -1.2 chorismate synthase compare
BWI76_RS20880 -2.8 -2.4 esterase compare
BWI76_RS25065 -2.8 -3.7 polyribonucleotide nucleotidyltransferase compare
BWI76_RS24900 -2.6 -2.1 DeoR family transcriptional regulator compare
BWI76_RS00345 -2.6 -4.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS22695 -2.5 -6.4 sulfate adenylyltransferase compare
BWI76_RS05015 -2.5 -2.0 transcriptional regulator compare
BWI76_RS26095 -2.4 -1.4 shikimate kinase compare
BWI76_RS22700 -2.4 -4.6 sulfate adenylyltransferase subunit 2 compare
BWI76_RS00960 -2.4 -2.9 acetolactate synthase 2 catalytic subunit compare
BWI76_RS20650 -2.4 -2.8 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS14075 -2.3 -1.5 TetR family transcriptional regulator compare
BWI76_RS00385 -2.3 -4.5 nitrogen assimilation regulatory protein compare
BWI76_RS27430 -2.3 -1.4 (p)ppGpp synthetase compare
BWI76_RS00390 -2.2 -4.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS10835 -2.2 -1.7 hypothetical protein compare
BWI76_RS23895 -2.2 -1.6 Xaa-Pro aminopeptidase compare
BWI76_RS05450 -2.2 -1.8 ribonuclease HI compare
BWI76_RS09655 -2.1 -3.8 leucine-responsive regulatory protein compare
BWI76_RS14415 -2.1 -2.8 transcriptional regulator, TetR family protein compare
BWI76_RS16965 -2.0 -1.7 murein lipoprotein compare
BWI76_RS04100 -2.0 -3.3 peptide chain release factor 3 compare
BWI76_RS23125 -2.0 -2.3 propanediol dehydratase small subunit compare
BWI76_RS23480 -1.9 -8.5 EAL domain-containing protein compare
BWI76_RS01800 -1.9 -2.7 glucose-6-phosphate isomerase compare
BWI76_RS25060 -1.9 -3.1 lipoprotein NlpI compare
BWI76_RS09970 -1.8 -3.5 porin OmpA compare
BWI76_RS10755 -1.8 -1.3 pyrimidine utilization flavin reductase protein F compare
BWI76_RS24945 -1.8 -1.2 glutamine amidotransferase compare
BWI76_RS06185 -1.7 -9.1 shikimate kinase II compare
BWI76_RS01275 -1.7 -5.9 LysR family transcriptional regulator compare
BWI76_RS11040 -1.7 -3.3 ribonuclease E compare
BWI76_RS06525 -1.7 -4.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS07185 -1.7 -1.8 hypothetical protein compare
BWI76_RS03665 -1.6 -1.5 ABC transporter ATP-binding protein compare
BWI76_RS26570 -1.6 -2.5 anion permease compare
BWI76_RS08720 -1.6 -1.7 imidazolonepropionase compare
BWI76_RS13955 -1.6 -2.0 hypothetical protein compare
BWI76_RS01210 -1.5 -2.4 tyrosine recombinase XerC compare
BWI76_RS14390 -1.5 -1.7 hypothetical protein compare
BWI76_RS23915 -1.5 -2.3 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS23970 -1.5 -1.6 mechanosensitive ion channel protein MscS compare
BWI76_RS13820 -1.5 -1.7 hypothetical protein compare
BWI76_RS08520 -1.5 -1.2 colicin transporter TolQ compare
BWI76_RS15835 -1.4 -0.9 hypothetical protein compare
BWI76_RS16360 -1.4 -1.2 electron transport complex subunit RsxB compare
BWI76_RS10950 -1.4 -2.4 MFS transporter compare
BWI76_RS15435 -1.4 -1.2 hypothetical protein compare
BWI76_RS04305 -1.4 -1.1 molecular chaperone DnaJ compare
BWI76_RS10935 -1.3 -3.4 glucan biosynthesis glucosyltransferase H compare
BWI76_RS09650 -1.3 -3.4 hypothetical protein compare
BWI76_RS25160 -1.3 -1.8 transcription elongation factor GreA compare
BWI76_RS19035 -1.3 -4.8 dTDP-rhamnosyl transferase compare
BWI76_RS11125 -1.3 -1.4 metal-dependent hydrolase compare
BWI76_RS06530 -1.3 -2.9 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS11835 -1.3 -1.8 putative regulatory protein MarR compare
BWI76_RS19690 -1.3 -2.4 LysR family transcriptional regulator compare
BWI76_RS08530 -1.3 -1.5 protein TolA compare
BWI76_RS17110 -1.3 -1.5 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS02410 -1.2 -1.4 EF-P beta-lysylation protein EpmB compare
BWI76_RS09335 -1.2 -1.2 baseplate assembly protein W compare
BWI76_RS13160 -1.2 -1.8 azoreductase compare
BWI76_RS07640 -1.2 -0.7 short chain dehydrogenase compare
BWI76_RS19010 -1.2 -1.8 polysaccharide pyruvyl transferase yvff compare
BWI76_RS21480 -1.2 -2.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS24100 -1.2 -3.6 YggS family pyridoxal phosphate enzyme compare
BWI76_RS23265 -1.2 -1.5 hypothetical protein compare
BWI76_RS10745 -1.2 -0.9 hypothetical protein compare
BWI76_RS05880 -1.2 -1.6 AraC-type DNA-binding domain-containing protein compare
BWI76_RS20695 -1.2 -2.8 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS18770 -1.2 -0.9 DNA gyrase inhibitor compare
BWI76_RS01350 -1.1 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS12155 -1.1 -2.8 hypothetical protein compare
BWI76_RS19330 -1.1 -0.9 HAD family hydrolase compare
BWI76_RS15825 -1.1 -1.2 hypothetical protein compare
BWI76_RS08535 -1.1 -1.6 translocation protein TolB compare
BWI76_RS21340 -1.1 -1.4 SoxR reducing system protein RseC compare
BWI76_RS02990 -1.1 -1.8 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS12495 -1.1 -1.4 2-Cys peroxiredoxin compare
BWI76_RS15060 -1.1 -1.9 MarR family transcriptional regulator compare
BWI76_RS02985 -1.1 -2.7 reactive intermediate/imine deaminase compare
BWI76_RS24075 -1.1 -1.8 glutathione synthase compare
BWI76_RS22705 -1.1 -3.8 siroheme synthase compare
BWI76_RS02530 -1.1 -1.6 tRNA dimethylallyltransferase compare
BWI76_RS25505 -1.1 -3.8 RNase E specificity factor CsrD compare
BWI76_RS01070 -1.0 -2.7 thiol reductase thioredoxin compare
BWI76_RS12145 -1.0 -0.9 hypothetical protein compare
BWI76_RS19325 -1.0 -0.8 mandelate racemase compare
BWI76_RS08525 -1.0 -0.9 colicin transporter compare
BWI76_RS20930 -1.0 -1.5 arsenate reductase (glutaredoxin) compare
BWI76_RS16635 -1.0 -1.9 carbonate dehydratase compare
BWI76_RS17200 -1.0 -1.2 hypothetical protein compare
BWI76_RS19205 -1.0 -2.7 putative proline iminopeptidase compare
BWI76_RS20490 -1.0 -1.6 hypothetical protein compare
BWI76_RS01200 -1.0 -1.1 diaminopimelate epimerase compare
BWI76_RS24585 -1.0 -1.3 glycerol dehydrogenase compare
BWI76_RS17030 -1.0 -2.8 cyclic nucleotide-binding domain-containing protein compare
BWI76_RS14320 -1.0 -1.7 hypothetical protein compare
BWI76_RS24485 -1.0 -1.4 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS14005 -1.0 -1.4 TetR family transcriptional regulator compare
BWI76_RS04845 -1.0 -2.9 nicotinate-nucleotide pyrophosphorylase compare
BWI76_RS10055 -1.0 -1.9 AraC family transcriptional regulator compare
BWI76_RS16035 -1.0 -1.4 biotin-independent malonate decarboxylase subunit beta compare
BWI76_RS16130 -1.0 -1.8 3-carboxy-cis,cis-muconate cycloisomerase compare
BWI76_RS23760 -1.0 -1.2 tRNA-Gly compare
BWI76_RS12780 -1.0 -1.8 hypothetical protein compare
BWI76_RS16485 -0.9 -1.2 ribonuclease T compare
BWI76_RS01095 -0.9 -1.3 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS00355 -0.9 -0.8 DNA polymerase I compare
BWI76_RS06800 -0.9 -0.9 DUF2496 domain-containing protein compare
BWI76_RS06880 -0.9 -1.4 biopolymer transport protein ExbD/TolR compare
BWI76_RS24920 -0.9 -1.3 YraN family protein compare
BWI76_RS02610 -0.9 -2.6 transcriptional regulator compare
BWI76_RS26410 -0.9 -1.2 membrane protein compare


Specific Phenotypes

None in this experiment

For Klebsiella michiganensis M5al in nitrogen source experiments

For nitrogen source L-Asparagine across organisms