Experiment set6IT042 for Bacteroides thetaiotaomicron VPI-5482

Compare to:

BHIS with Dimetridazole 0.025 mM

200 most detrimental genes:

  gene name fitness t score description  
BT0877 +7.2 13.4 ferredoxin domain containing protein (NCBI ptt file) compare
BT4703 +4.5 16.7 chloromuconate cycloisomerase (NCBI ptt file) compare
BT2080 +4.1 22.1 L-cysteine desulfidase cdsB (from data) compare
BT1112 +3.1 2.7 transposase (NCBI ptt file) compare
BT2706 +2.5 11.5 methionine aminopeptidase (NCBI ptt file) compare
BT0405 +2.2 2.2 hypothetical protein (NCBI ptt file) compare
BT2184 +2.1 5.0 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2853 +2.1 3.2 hypothetical protein (NCBI ptt file) compare
BT4757 +2.1 9.7 hypothetical protein (NCBI ptt file) compare
BT0944 +1.9 2.5 hypothetical protein (NCBI ptt file) compare
BT0927 +1.9 2.5 two-component system sensor histidine kinase (NCBI ptt file) compare
BT4755 +1.9 8.9 putative two-component system sensor histidine kinase, putative heat shock protein (NCBI ptt file) compare
BT0572 +1.8 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1868 +1.8 2.4 conserved hypothetical protein (NCBI ptt file) compare
BT3770 +1.8 3.1 transcriptional regulator (NCBI ptt file) compare
BT1212 +1.8 4.6 outer membrane efflux protein (NCBI ptt file) compare
BT2487 +1.8 2.4 hypothetical protein (NCBI ptt file) compare
BT1195 +1.8 3.0 monofunctional biosynthetic peptidoglycan transglycosylase (NCBI ptt file) compare
BT1524 +1.7 1.5 hypothetical protein (NCBI ptt file) compare
BT4609 +1.7 4.9 conserved hypothetical protein (NCBI ptt file) compare
BT1607 +1.7 4.1 methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase (NCBI ptt file) compare
BT1080 +1.7 3.1 hypothetical protein (NCBI ptt file) compare
BT4756 +1.7 5.8 hypothetical protein (NCBI ptt file) compare
BT1419 +1.7 3.2 hypothetical protein (NCBI ptt file) compare
BT2323 +1.6 2.8 conserved hypothetical protein (NCBI ptt file) compare
BT0443 +1.6 2.1 thermostable beta-glucosidase B (NCBI ptt file) compare
BT1380 +1.6 3.0 imidazole glycerol phosphate synthase subunit hisH (NCBI ptt file) compare
BT0177 +1.6 3.3 hypothetical protein (NCBI ptt file) compare
BT0515 +1.6 4.4 terminal quinol oxidase, subunit, putative (doxD-like) (NCBI ptt file) compare
BT1150 +1.5 6.5 conserved hypothetical protein (NCBI ptt file) compare
BT0816 +1.5 2.0 conserved hypothetical protein (NCBI ptt file) compare
BT3022 +1.5 1.9 hypothetical protein (NCBI ptt file) compare
BT0848 +1.5 2.7 hypothetical protein (NCBI ptt file) compare
BT0544 +1.5 2.8 ammonium transporter (NCBI ptt file) compare
BT0752 +1.5 1.9 putative RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2541 +1.4 5.9 putative calcium-transporting ATPase (NCBI ptt file) compare
BT1197 +1.4 2.2 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2302 +1.4 1.6 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT4424 +1.4 3.1 sorbitol dehydrogenase (NCBI ptt file) compare
BT0875 +1.4 4.1 beta-ureidopropionase (NCBI ptt file) compare
BT0838 +1.4 4.4 putative RNA methyltransferase (NCBI ptt file) compare
BT0134 +1.4 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT1382 +1.4 5.6 conserved hypothetical protein (NCBI ptt file) compare
BT0739 +1.3 3.0 hypothetical protein (NCBI ptt file) compare
BT0965 +1.3 3.7 putative anti-sigma factor (NCBI ptt file) compare
BT1895 +1.3 3.2 hypothetical protein (NCBI ptt file) compare
BT0475 +1.3 1.6 putative phosphoheptose isomerase (NCBI ptt file) compare
BT0758 +1.3 2.0 acetyltransferase (NCBI ptt file) compare
BT3860 +1.3 3.3 conserved hypothetical protein (NCBI ptt file) compare
BT4598 +1.3 2.2 hypothetical protein (NCBI ptt file) compare
BT0241 +1.3 1.4 hypothetical protein (NCBI ptt file) compare
BT0215 +1.3 1.7 iron uptake regulatory protein (NCBI ptt file) compare
BT3810 +1.3 4.6 putative endothelin-converting enzyme (NCBI ptt file) compare
BT1260 +1.3 2.2 putative peptidase (NCBI ptt file) compare
BT0673 +1.3 2.9 NADP(H) oxidoreductase (NCBI ptt file) compare
BT1262 +1.3 1.6 putative transcriptional regulator (NCBI ptt file) compare
BT3747 +1.3 2.8 hypothetical protein (NCBI ptt file) compare
BT3882 +1.3 1.7 putative DNA binding protein (NCBI ptt file) compare
BT1740 +1.2 2.4 hypothetical protein (NCBI ptt file) compare
BT0414 +1.2 1.7 sulfate adenylyltransferase subunit 2 (NCBI ptt file) compare
BT0291 +1.2 2.4 integrase (NCBI ptt file) compare
BT1812 +1.2 3.9 putative chaperone DnAJ (NCBI ptt file) compare
BT4128 +1.2 4.7 conserved hypothetical protein (NCBI ptt file) compare
BT4593 +1.2 3.4 conserved hypothetical protein (NCBI ptt file) compare
BT0783 +1.2 1.5 hypothetical protein (NCBI ptt file) compare
BT1296 +1.2 3.0 V-type ATP synthase subunit I (NCBI ptt file) compare
BT4453 +1.2 1.6 6-pyruvoyl-tetrahydropterin synthase (NCBI ptt file) compare
BT4590 +1.2 2.3 conserved hypothetical protein (NCBI ptt file) compare
BT0564 +1.2 3.1 putative ABC transporter permease protein (NCBI ptt file) compare
BT0006 +1.1 2.4 hypothetical protein (NCBI ptt file) compare
BT1929 +1.1 2.7 transposase (NCBI ptt file) compare
BT4325 +1.1 2.1 hypothetical protein (NCBI ptt file) compare
BT4765 +1.1 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1623 +1.1 2.4 putative membrane protein (NCBI ptt file) compare
BT1583 +1.1 1.6 putative protein disulfide isomerase (NCBI ptt file) compare
BT1501 +1.1 2.1 major outer membrane protein OmpA (NCBI ptt file) compare
BT1072 +1.1 1.6 hypothetical protein (NCBI ptt file) compare
BT0736 +1.1 2.4 putative transport protein (NCBI ptt file) compare
BT1168 +1.1 1.9 N-acetylmuramoyl-L-alanine amidase (NCBI ptt file) compare
BT2741 +1.1 1.9 sigma-54 modulation protein (NCBI ptt file) compare
BT0937 +1.1 1.8 hypothetical protein (NCBI ptt file) compare
BT2944 +1.1 4.7 putative UDP-N-acetylglucosamine 2-epimerase (NCBI ptt file) compare
BT1565 +1.1 1.1 hypothetical protein (NCBI ptt file) compare
BT0481 +1.1 2.0 polysaccharide export outer membrane protein (NCBI ptt file) compare
BT1406 +1.1 3.0 transcriptional regulator, TetR family (NCBI ptt file) compare
BT0708 +1.1 2.4 hypothetical protein (NCBI ptt file) compare
BT0815 +1.1 1.9 conserved hypothetical protein (NCBI ptt file) compare
BT0303 +1.1 4.4 putative patatin-like phospholipase (NCBI ptt file) compare
BT4003 +1.1 1.6 stationary-phase survival protein SurE (NCBI ptt file) compare
BT_2008 +1.1 1.5 hypothetical protein (RefSeq) compare
BT1232 +1.1 1.2 hypothetical protein (NCBI ptt file) compare
BT1263 +1.1 1.0 putative protease I (NCBI ptt file) compare
BT0513 +1.1 2.4 hypothetical protein (NCBI ptt file) compare
BT0242 +1.1 1.8 putative polysaccharide deacetylase (NCBI ptt file) compare
BT0971 +1.1 2.7 conserved hypothetical protein (NCBI ptt file) compare
BT2045 +1.1 0.9 hypothetical protein (NCBI ptt file) compare
BT0842 +1.0 1.5 hypothetical protein (NCBI ptt file) compare
BT3762 +1.0 3.6 arginine repressor, transcriptional regulator of arginine metabolism (NCBI ptt file) compare
BT1594 +1.0 2.4 putative ferredoxin (NCBI ptt file) compare
BT0735 +1.0 1.7 aspartate decarboxylase AsdA (NCBI ptt file) compare
BT4208 +1.0 4.6 phosphohydrolase (NCBI ptt file) compare
BT1617 +1.0 1.3 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2179 +1.0 3.8 putative DNA mismatch repair protein (NCBI ptt file) compare
BT4360 +1.0 3.0 hypothetical protein (NCBI ptt file) compare
BT3724 +1.0 3.2 cationic outer membrane protein precursor (NCBI ptt file) compare
BT0311 +1.0 3.4 lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex (NCBI ptt file) compare
BT1855 +1.0 1.7 putative methyl transferase (NCBI ptt file) compare
BT1149 +1.0 2.0 Type II restriction enzyme HpaII (NCBI ptt file) compare
BT0658 +1.0 1.5 hypothetical protein (NCBI ptt file) compare
BT0128 +1.0 2.8 hypothetical protein (NCBI ptt file) compare
BT1984 +1.0 1.3 transcriptional regulator (NCBI ptt file) compare
BT0855 +1.0 2.6 two-component system sensor histidine kinase (NCBI ptt file) compare
BT0390 +1.0 2.6 putative O-antigen export protein (NCBI ptt file) compare
BT0352 +1.0 1.1 conserved hypothetical protein (NCBI ptt file) compare
BT1567 +1.0 2.1 conserved hypothetical protein (NCBI ptt file) compare
BT2010 +1.0 1.5 hypothetical protein (NCBI ptt file) compare
BT4587 +1.0 2.2 conserved hypothetical protein (NCBI ptt file) compare
BT0474 +1.0 2.5 D-glycero-D-manno-heptose 1-phosphate kinase (NCBI ptt file) compare
BT4300 +1.0 2.1 transcription regulator, CRP family (NCBI ptt file) compare
BT4322 +1.0 1.6 conserved hypothetical protein, with a diacylglycerol kinase catalytic domain (NCBI ptt file) compare
BT0878 +1.0 1.0 ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT0071 +1.0 2.2 hypothetical protein (NCBI ptt file) compare
BT3682 +1.0 2.6 hypothetical protein (NCBI ptt file) compare
BT3073 +0.9 3.2 putative TIM-barrel enzyme, possible dehydrogenase, contains a highly conserved dihydrouridine synthase domain (NCBI ptt file) compare
BT0857 +0.9 2.4 outer membrane protein TolC, putative (NCBI ptt file) compare
BT4467 +0.9 2.2 hypothetical protein (NCBI ptt file) compare
BT3317 +0.9 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1433 +0.9 3.5 putative oxidoreductase (NCBI ptt file) compare
BT1549 +0.9 3.3 putative secreted peptidase (NCBI ptt file) compare
BT0704 +0.9 1.1 phosphoribosylglycinamide formyltransferase 2 (NCBI ptt file) compare
BT4702 +0.9 0.8 dihydroxynapthoic acid synthetase (NCBI ptt file) compare
BT1561 +0.9 0.5 hypothetical protein (NCBI ptt file) compare
BT1268 +0.9 2.7 transporter, AcrB/D/F family (NCBI ptt file) compare
BT0380 +0.9 2.4 nucleotide sugar epimerase (NCBI ptt file) compare
BT1011 +0.9 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0584 +0.9 1.1 putative outer membrane protein (NCBI ptt file) compare
BT1273 +0.9 2.4 L-fucose isomerase (NCBI ptt file) compare
BT2075 +0.9 3.5 acyl-ACP thioesterase (NCBI ptt file) compare
BT3712 +0.9 2.3 ribosomal large subunit pseudouridine synthase D (NCBI ptt file) compare
BT0925 +0.9 1.2 ABC transporter, ATP-binding protein (NCBI ptt file) compare
BT1200 +0.9 1.6 hypothetical protein (NCBI ptt file) compare
BT3383 +0.9 3.1 hypothetical protein (NCBI ptt file) compare
BT0017 +0.9 1.7 hypothetical protein (NCBI ptt file) compare
BT4504 +0.9 2.4 conserved hypothetical protein (NCBI ptt file) compare
BT0651 +0.9 1.1 thiamine biosynthesis protein ThiG (NCBI ptt file) compare
BT0473 +0.9 2.5 putative glycosyltransferase (NCBI ptt file) compare
BT0148 +0.9 2.0 putative hemolysin (NCBI ptt file) compare
BT4451 +0.9 1.4 putative MTA/SAH nucleosidase (NCBI ptt file) compare
BT4198 +0.9 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0081 +0.9 1.5 hypothetical protein (NCBI ptt file) compare
BT4722 +0.9 2.4 RNA polymerase ECF-type sigma factor (NCBI ptt file) compare
BT2046 +0.9 0.6 putative cardiolipin synthetase (NCBI ptt file) compare
BT0792 +0.9 1.9 xylulokinase (EC 2.7.1.17) (from data) compare
BT0015 +0.9 1.5 rteB, two-component system response regulator (NCBI ptt file) compare
BT2415 +0.9 3.9 aspartate aminotransferase (NCBI ptt file) compare
BT0790 +0.9 1.6 phosphomethylpyrimidine kinase (NCBI ptt file) compare
BT1653 +0.9 2.7 hypothetical protein (NCBI ptt file) compare
BT2594 +0.9 2.4 conserved protein found in conjugate transposon (NCBI ptt file) compare
BT0686 +0.9 3.5 putative uracil permease (uracil transporter) (NCBI ptt file) compare
BT0547 +0.9 2.9 aspartate aminotransferase (NCBI ptt file) compare
BT1188 +0.9 1.6 putative transcription regulator (NCBI ptt file) compare
BT3264 +0.9 3.3 conserved hypothetical protein (NCBI ptt file) compare
BT0158 +0.9 2.1 Na(+)/H(+) antiporter (NCBI ptt file) compare
BT0549 +0.9 1.6 putative thioredoxin (NCBI ptt file) compare
BT0470 +0.9 3.2 hypothetical protein (NCBI ptt file) compare
BT1109 +0.9 2.3 ferritin A (NCBI ptt file) compare
BT0568 +0.9 2.7 hypothetical protein (NCBI ptt file) compare
BT4649 +0.9 1.0 hypothetical protein (NCBI ptt file) compare
BT4449 +0.9 1.8 putative dehydrogenase (NCBI ptt file) compare
BT1145 +0.9 1.1 glucose-inhibited division protein (NCBI ptt file) compare
BT4693 +0.9 2.3 cation efflux system protein (NCBI ptt file) compare
BT0271 +0.8 2.1 hypothetical protein (NCBI ptt file) compare
BT4032 +0.8 2.1 conserved hypothetical protein, putative non-specific DNA-binding protein (NCBI ptt file) compare
BT2471 +0.8 2.0 hypothetical protein (NCBI ptt file) compare
BT1509 +0.8 1.8 integrase (NCBI ptt file) compare
BT0820 +0.8 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT0510 +0.8 2.9 putative heme biosynthesis protein (NCBI ptt file) compare
BT1582 +0.8 4.0 putative methyltransferase (NCBI ptt file) compare
BT1644 +0.8 2.2 putative CPS biosynthesis glycosyltransferase (NCBI ptt file) compare
BT0683 +0.8 1.9 alpha-glucosidase (NCBI ptt file) compare
BT0498 +0.8 1.6 hypothetical protein (NCBI ptt file) compare
BT4696 +0.8 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT4573 +0.8 1.5 conserved hypothetical protein (NCBI ptt file) compare
BT0876 +0.8 0.7 conserved hypothetical protein (NCBI ptt file) compare
BT4545 +0.8 1.2 hypothetical protein (NCBI ptt file) compare
BT1994 +0.8 1.3 hypothetical protein (NCBI ptt file) compare
BT4658 +0.8 2.4 glucuronyl hydrolase (NCBI ptt file) compare
BT3140 +0.8 1.8 conserved hypothetical protein (NCBI ptt file) compare
BT4161 +0.8 1.1 hypothetical protein (NCBI ptt file) compare
BT1516 +0.8 1.6 replicative DNA helicase (NCBI ptt file) compare
BT1411 +0.8 1.1 methylated-DNA--protein-cysteine methyltransferase (NCBI ptt file) compare
BT0039 +0.8 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT1493 +0.8 1.7 conserved hypothetical protein (NCBI ptt file) compare
BT2042 +0.8 0.8 tRNA and rRNA cytosine-C5-methylase (NCBI ptt file) compare
BT2788 +0.8 3.0 chromate transport protein (NCBI ptt file) compare
BT2538 +0.8 1.6 hypothetical protein (NCBI ptt file) compare
BT3128 +0.8 1.7 putative xanthosine triphosphate pyrophosphatase (NCBI ptt file) compare
BT1919 +0.8 1.8 conserved hypothetical protein with a conserved domain (NCBI ptt file) compare
BT1148 +0.8 1.6 putative NADH dehydrogenase/NAD(P)H nitroreductase (NCBI ptt file) compare
BT0432 +0.8 2.4 putative endonuclease BB0411 (NCBI ptt file) compare


Specific Phenotypes

For 10 genes in this experiment

For stress Dimetridazole in Bacteroides thetaiotaomicron VPI-5482

For stress Dimetridazole across organisms