Experiment set6IT040 for Klebsiella michiganensis M5al

Compare to:

L-Histidine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS20965 -9.0 -5.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS11965 -8.3 -5.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS00850 -8.1 -9.6 acetylglutamate kinase compare
BWI76_RS04160 -7.8 -7.6 phosphoserine phosphatase compare
BWI76_RS09755 -7.3 -7.1 phosphoserine transaminase compare
BWI76_RS05835 -7.2 -5.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS04250 -7.1 -7.1 homoserine kinase compare
BWI76_RS24285 -7.0 -8.4 cystathionine beta-lyase compare
BWI76_RS04685 -6.9 -9.4 putative leucine operon leader peptide compare
BWI76_RS05840 -6.8 -4.7 glutamate 5-kinase compare
BWI76_RS04255 -6.6 -9.1 threonine synthase compare
BWI76_RS08385 -6.5 -3.8 citrate (Si)-synthase compare
BWI76_RS11855 -6.5 -7.1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS21265 -6.5 -15.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04245 -6.4 -13.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS07065 -6.3 -6.6 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS04665 -6.3 -20.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00990 -6.3 -10.0 ketol-acid reductoisomerase compare
BWI76_RS11850 -6.3 -10.0 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS04670 -6.3 -10.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS23360 -6.1 -4.2 diaminopimelate decarboxylase compare
BWI76_RS04675 -6.1 -7.2 3-isopropylmalate dehydrogenase compare
BWI76_RS25320 -6.1 -8.8 glutamate synthase compare
BWI76_RS01210 -6.1 -4.4 tyrosine recombinase XerC compare
BWI76_RS04470 -6.0 -10.5 carbamoyl phosphate synthase large subunit compare
BWI76_RS25115 -6.0 -7.3 argininosuccinate synthase compare
BWI76_RS05015 -5.9 -4.1 transcriptional regulator compare
BWI76_RS00385 -5.9 -8.0 nitrogen assimilation regulatory protein compare
BWI76_RS26085 -5.9 -3.9 3-dehydroquinate synthase compare
BWI76_RS20895 -5.9 -6.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS11840 -5.9 -2.9 tryptophan synthase subunit alpha compare
BWI76_RS01655 -5.8 -7.2 homoserine O-succinyltransferase compare
BWI76_RS23920 -5.8 -5.0 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS27385 -5.8 -7.9 orotate phosphoribosyltransferase compare
BWI76_RS00785 -5.8 -7.9 cystathionine gamma-synthase compare
BWI76_RS11860 -5.8 -10.4 anthranilate synthase component I compare
BWI76_RS23220 -5.7 -9.0 amino-acid N-acetyltransferase compare
BWI76_RS21475 -5.7 -5.2 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS02995 -5.6 -7.8 aspartate carbamoyltransferase compare
BWI76_RS00855 -5.6 -8.2 argininosuccinate lyase compare
BWI76_RS20350 -5.6 -7.1 amidophosphoribosyltransferase compare
BWI76_RS00805 -5.5 -4.9 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS07070 -5.5 -6.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS01615 -5.5 -10.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS22755 -5.5 -8.3 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04645 -5.4 -5.0 3-dehydroquinase compare
BWI76_RS04465 -5.4 -6.0 carbamoyl-phosphate synthase small subunit compare
BWI76_RS21465 -5.3 -4.9 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS09910 -5.3 -19.1 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS00980 -5.3 -12.3 PLP-dependent threonine dehydratase compare
BWI76_RS01610 -5.2 -5.4 phosphoribosylamine--glycine ligase compare
BWI76_RS22805 -5.2 -12.6 GTP diphosphokinase compare
BWI76_RS00965 -5.1 -2.0 acetolactate synthase 2 small subunit compare
BWI76_RS09760 -5.1 -4.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS00845 -5.1 -11.3 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS00400 -5.0 -3.2 glutamine synthetase compare
BWI76_RS00975 -4.9 -10.0 dihydroxy-acid dehydratase compare
BWI76_RS04680 -4.9 -10.2 2-isopropylmalate synthase compare
BWI76_RS08735 -4.7 -6.0 Urocanate hydratase (EC 4.2.1.49) (from data) conserved
BWI76_RS01350 -4.7 -1.8 NAD(P)H-flavin reductase compare
BWI76_RS22765 -4.6 -13.0 sulfite reductase subunit alpha compare
BWI76_RS25645 -4.6 -8.8 shikimate dehydrogenase compare
BWI76_RS04240 -4.6 -2.0 thr operon leader peptide compare
BWI76_RS25315 -4.6 -11.4 glutamate synthase large subunit compare
BWI76_RS10990 -4.5 -4.1 dihydroorotase compare
BWI76_RS23365 -4.5 -5.2 LysR family transcriptional regulator compare
BWI76_RS11845 -4.4 -2.6 tryptophan synthase subunit beta compare
BWI76_RS05200 -4.3 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS03010 -4.3 -5.8 ornithine carbamoyltransferase compare
BWI76_RS00390 -4.2 -4.3 two-component system sensor histidine kinase NtrB compare
BWI76_RS23240 -4.2 -4.1 exonuclease V subunit gamma compare
BWI76_RS22760 -4.2 -6.4 sulfite reductase subunit beta compare
BWI76_RS08725 -4.1 -4.7 Formiminoglutamase (EC 3.5.3.8) (from data) conserved
BWI76_RS08180 -4.1 -6.1 asparagine synthase B compare
BWI76_RS09660 -4.1 -2.8 DNA translocase FtsK compare
BWI76_RS08720 -4.0 -2.6 imidazolonepropionase compare
BWI76_RS08740 -3.8 -7.2 Histidine ammonia-lyase (EC 4.3.1.3) (from data) conserved
BWI76_RS18630 -3.7 -6.8 nitrogen assimilation transcriptional regulator conserved
BWI76_RS23230 -3.6 -5.4 exodeoxyribonuclease V subunit beta compare
BWI76_RS17720 -3.6 -1.9 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS22690 -3.5 -2.6 adenylyl-sulfate kinase compare
BWI76_RS23265 -3.5 -3.7 hypothetical protein compare
BWI76_RS27390 -3.4 -3.3 ribonuclease PH compare
BWI76_RS20355 -3.4 -2.5 colicin V production protein compare
BWI76_RS00985 -3.2 -6.2 transcriptional regulator IlvY compare
BWI76_RS09970 -3.1 -5.8 porin OmpA compare
BWI76_RS20380 -3.0 -2.0 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS26055 -3.0 -8.3 siroheme synthase compare
BWI76_RS20435 -2.9 -1.4 chorismate synthase compare
BWI76_RS02735 -2.8 -6.2 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS09645 -2.8 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS00840 -2.7 -10.6 acetylornithine deacetylase compare
BWI76_RS16965 -2.7 -6.0 murein lipoprotein compare
BWI76_RS01200 -2.7 -2.4 diaminopimelate epimerase compare
BWI76_RS19495 -2.6 -1.7 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS27440 -2.6 -3.5 DNA helicase RecG compare
BWI76_RS02530 -2.5 -3.4 tRNA dimethylallyltransferase compare
BWI76_RS00940 -2.5 -5.3 transcriptional regulator HdfR compare
BWI76_RS26460 -2.5 -5.7 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS26455 -2.4 -4.9 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS23480 -2.4 -10.7 EAL domain-containing protein compare
BWI76_RS20640 -2.3 -5.5 cysteine synthase A compare
BWI76_RS17980 -2.3 -4.2 RNA chaperone ProQ compare
BWI76_RS23885 -2.2 -2.1 2-octaprenylphenol hydroxylase compare
BWI76_RS21910 -2.2 -6.6 glyoxylate/hydroxypyruvate reductase A compare
BWI76_RS21450 -2.2 -1.7 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS14435 -2.1 -2.3 glutamine ABC transporter ATP-binding protein compare
BWI76_RS00960 -2.0 -5.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS21905 -2.0 -4.2 class II aldolase compare
BWI76_RS25065 -1.9 -2.2 polyribonucleotide nucleotidyltransferase compare
BWI76_RS06535 -1.9 -5.1 endopeptidase La compare
BWI76_RS09650 -1.9 -4.6 hypothetical protein compare
BWI76_RS09655 -1.9 -6.3 leucine-responsive regulatory protein compare
BWI76_RS17290 -1.9 -3.9 formyltetrahydrofolate deformylase compare
BWI76_RS08535 -1.9 -2.8 translocation protein TolB compare
BWI76_RS15825 -1.9 -2.7 hypothetical protein compare
BWI76_RS26570 -1.9 -2.9 anion permease compare
BWI76_RS20490 -1.8 -2.9 hypothetical protein compare
BWI76_RS17975 -1.7 -3.8 tail-specific protease compare
BWI76_RS09635 -1.7 -2.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS15990 -1.7 -5.4 serine protease compare
BWI76_RS14390 -1.7 -2.3 hypothetical protein compare
BWI76_RS15850 -1.6 -1.2 DUF1317 domain-containing protein compare
BWI76_RS09030 -1.6 -5.1 transpeptidase compare
BWI76_RS22700 -1.6 -3.6 sulfate adenylyltransferase subunit 2 compare
BWI76_RS08525 -1.6 -2.9 colicin transporter compare
BWI76_RS00180 -1.6 -1.3 F0F1 ATP synthase subunit epsilon compare
BWI76_RS01385 -1.6 -3.5 potassium transporter compare
BWI76_RS15835 -1.5 -1.0 hypothetical protein compare
BWI76_RS00355 -1.5 -3.4 DNA polymerase I compare
BWI76_RS19480 -1.5 -1.2 transcriptional regulator compare
BWI76_RS21900 -1.5 -4.7 amino acid ABC transporter permease/ATP-binding protein compare
BWI76_RS20970 -1.5 -1.6 phosphoribosylglycinamide formyltransferase compare
BWI76_RS12390 -1.4 -2.5 antibiotic biosynthesis monooxygenase compare
BWI76_RS11700 -1.4 -1.6 hypothetical protein compare
BWI76_RS26440 -1.4 -1.8 hypothetical protein compare
BWI76_RS20440 -1.4 -1.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS10290 -1.4 -6.4 transcriptional regulator compare
BWI76_RS05120 -1.4 -6.6 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS02725 -1.3 -1.3 HxlR family transcriptional regulator compare
BWI76_RS09615 -1.3 -1.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS10935 -1.3 -3.2 glucan biosynthesis glucosyltransferase H compare
BWI76_RS06490 -1.3 -6.1 cytochrome ubiquinol oxidase subunit I compare
BWI76_RS12090 -1.3 -1.1 HNH endonuclease compare
BWI76_RS21480 -1.3 -3.5 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS20915 -1.3 -4.7 peroxiredoxin compare
BWI76_RS22695 -1.2 -3.2 sulfate adenylyltransferase compare
BWI76_RS08495 -1.2 -3.6 cytochrome bd-I ubiquinol oxidase subunit I compare
BWI76_RS12870 -1.2 -1.8 putative phytanoyl-CoA dioxygenase compare
BWI76_RS03105 -1.2 -1.1 myo-inosose-2 dehydratase compare
BWI76_RS04305 -1.2 -1.2 molecular chaperone DnaJ compare
BWI76_RS12790 -1.2 -1.1 lactate dehydrogenase compare
BWI76_RS02050 -1.2 -2.3 CidA/LrgA family protein compare
BWI76_RS02990 -1.2 -3.2 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS26075 -1.2 -2.2 DNA adenine methylase compare
BWI76_RS06495 -1.2 -5.2 cytochrome ubiquinol oxidase subunit II compare
BWI76_RS20155 -1.2 -1.2 NADH-quinone oxidoreductase subunit I compare
BWI76_RS04270 -1.1 -3.9 transaldolase compare
BWI76_RS22485 -1.1 -2.6 hypothetical protein compare
BWI76_RS15830 -1.1 -2.2 hypothetical protein compare
BWI76_RS06015 -1.1 -1.3 hypothetical protein compare
BWI76_RS17110 -1.1 -1.6 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS22120 -1.1 -4.7 glutamate--cysteine ligase compare
BWI76_RS20995 -1.1 -3.5 RNA degradosome polyphosphate kinase compare
BWI76_RS23895 -1.1 -1.4 Xaa-Pro aminopeptidase compare
BWI76_RS11125 -1.1 -1.5 metal-dependent hydrolase compare
BWI76_RS10930 -1.1 -6.9 glucan biosynthesis protein G compare
BWI76_RS06295 -1.1 -2.9 S-adenosylmethionine:tRNA ribosyltransferase-isomerase compare
BWI76_RS10835 -1.1 -1.4 hypothetical protein compare
BWI76_RS21100 -1.1 -2.1 nucleoside-diphosphate kinase compare
BWI76_RS08530 -1.1 -1.9 protein TolA compare
BWI76_RS20650 -1.1 -2.0 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS19935 -1.1 -1.5 hypothetical protein compare
BWI76_RS19470 -1.1 -1.9 DNA-binding response regulator compare
BWI76_RS16235 -1.1 -3.5 membrane protein compare
BWI76_RS11040 -1.1 -3.5 ribonuclease E compare
BWI76_RS01070 -1.1 -3.7 thiol reductase thioredoxin compare
BWI76_RS21350 -1.0 -1.9 anti-RNA polymerase sigma factor SigE compare
BWI76_RS17195 -1.0 -2.2 hypothetical protein compare
BWI76_RS27435 -1.0 -2.8 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS14770 -1.0 -1.3 PTS IIA 2 domain protein compare
BWI76_RS25960 -1.0 -1.9 NUDIX hydrolase compare
BWI76_RS01890 -1.0 -3.6 transcriptional regulator Zur compare
BWI76_RS14305 -1.0 -2.9 metallophosphoesterase compare
BWI76_RS09640 -1.0 -3.0 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS07645 -1.0 -1.5 short-chain dehydrogenase/reductase compare
BWI76_RS19010 -1.0 -2.2 polysaccharide pyruvyl transferase yvff compare
BWI76_RS06485 -1.0 -2.3 cytochrome o ubiquinol oxidase subunit III compare
BWI76_RS09335 -1.0 -1.2 baseplate assembly protein W compare
BWI76_RS15640 -1.0 -4.0 hypothetical protein compare
BWI76_RS22810 -1.0 -2.2 23S rRNA (uracil(1939)-C(5))-methyltransferase compare
BWI76_RS27430 -1.0 -1.1 (p)ppGpp synthetase compare
BWI76_RS18820 -1.0 -4.3 nitrogenase molybdenum-iron protein subunit beta compare
BWI76_RS11440 -1.0 -1.0 hypothetical protein compare
BWI76_RS26245 -1.0 -2.1 transcriptional regulator compare
BWI76_RS01870 -1.0 -2.2 diacylglycerol kinase compare
BWI76_RS06525 -1.0 -3.7 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS15840 -1.0 -2.4 prophage protein compare
BWI76_RS17045 -1.0 -1.3 hypothetical protein compare
BWI76_RS09330 -0.9 -2.2 baseplate assembly protein V compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Histidine in Klebsiella michiganensis M5al

For nitrogen source L-Histidine across organisms