Experiment set6IT040 for Klebsiella michiganensis M5al

Compare to:

L-Histidine nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS07510 +1.3 4.3 hypothetical protein compare
BWI76_RS00575 +1.2 8.9 DNA-binding protein compare
BWI76_RS12235 +1.1 2.9 hypothetical protein compare
BWI76_RS05070 +1.1 2.8 type II secretion system protein GspH compare
BWI76_RS02580 +1.1 1.8 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS20720 +1.1 2.3 hypothetical protein compare
BWI76_RS02745 +1.0 2.1 hypothetical protein compare
BWI76_RS06910 +1.0 2.1 transcriptional regulator compare
BWI76_RS15130 +1.0 3.1 hypothetical protein compare
BWI76_RS26410 +1.0 2.8 membrane protein compare
BWI76_RS23530 +0.9 3.0 MarR family transcriptional regulator compare
BWI76_RS08730 +0.9 5.4 histidine utilization repressor compare
BWI76_RS16275 +0.9 1.8 fumarate hydratase FumA compare
BWI76_RS08330 +0.9 1.9 hypothetical protein compare
BWI76_RS20795 +0.9 1.6 ethanolamine catabolic microcompartment shell protein EutN compare
BWI76_RS06680 +0.9 1.4 hypothetical protein compare
BWI76_RS08310 +0.9 2.2 potassium-transporting ATPase subunit C compare
BWI76_RS11780 +0.9 2.5 2-deoxyglucose-6-phosphatase compare
BWI76_RS08275 +0.9 2.0 LexA regulated protein compare
BWI76_RS19460 +0.9 2.4 lipoprotein compare
BWI76_RS15790 +0.9 2.8 replication protein compare
BWI76_RS08825 +0.8 2.0 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS08350 +0.8 2.7 carboxylase compare
BWI76_RS09490 +0.8 2.0 DNA-binding response regulator compare
BWI76_RS05520 +0.8 2.0 hypothetical protein compare
BWI76_RS24390 +0.8 1.5 hypothetical protein compare
BWI76_RS15360 +0.8 1.6 hypothetical protein compare
BWI76_RS23320 +0.8 1.4 hypothetical protein compare
BWI76_RS19870 +0.8 1.9 malate:quinone oxidoreductase compare
BWI76_RS11820 +0.8 1.2 short-chain dehydrogenase/reductase SDR compare
BWI76_RS20715 +0.8 2.0 RpoE-regulated lipoprotein compare
BWI76_RS16455 +0.8 1.1 superoxide dismutase compare
BWI76_RS24525 +0.8 2.7 urease accessory protein UreG compare
BWI76_RS08640 +0.8 1.9 multidrug efflux pump-associated protein, AcrZ family compare
BWI76_RS20335 +0.8 2.5 zinc transporter compare
BWI76_RS11435 +0.8 1.1 hypothetical protein compare
BWI76_RS13990 +0.8 2.1 allophanate hydrolase compare
BWI76_RS22855 +0.7 1.8 hypothetical protein compare
BWI76_RS06595 +0.7 2.1 hypothetical protein compare
BWI76_RS13380 +0.7 2.2 hypothetical protein compare
BWI76_RS13495 +0.7 3.1 hypothetical protein compare
BWI76_RS12345 +0.7 2.1 nitrite transporter compare
BWI76_RS05005 +0.7 2.3 polynucleotide adenylyltransferase compare
BWI76_RS23140 +0.7 1.7 carboxysome shell protein compare
BWI76_RS13170 +0.7 1.7 methyltransferase compare
BWI76_RS12125 +0.7 2.6 hypothetical protein compare
BWI76_RS21200 +0.7 2.0 aldose epimerase compare
BWI76_RS17805 +0.7 1.1 membrane protein compare
BWI76_RS05045 +0.7 1.2 general secretion pathway protein GspM compare
BWI76_RS13515 +0.7 3.0 amino acid permease compare
BWI76_RS13805 +0.7 1.8 inorganic diphosphatase compare
BWI76_RS11150 +0.7 1.1 membrane protein compare
BWI76_RS26005 +0.7 2.9 glutamine amidotransferase compare
BWI76_RS13770 +0.7 2.8 alkylhydroperoxidase domain protein compare
BWI76_RS11980 +0.7 1.2 DeoR family transcriptional regulator compare
BWI76_RS14835 +0.7 1.3 hypothetical protein compare
BWI76_RS00370 +0.7 2.2 GTPase-activating protein compare
BWI76_RS22265 +0.7 1.9 NADH:flavorubredoxin oxidoreductase compare
BWI76_RS10945 +0.6 2.2 SecY/SecA suppressor protein compare
BWI76_RS12200 +0.6 2.0 hypothetical protein compare
BWI76_RS03045 +0.6 1.0 hypothetical protein compare
BWI76_RS08980 +0.6 1.0 DNA starvation/stationary phase protection protein compare
BWI76_RS23050 +0.6 1.9 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS18425 +0.6 3.4 phosphohydrolase compare
BWI76_RS24035 +0.6 1.9 hypothetical protein compare
BWI76_RS07360 +0.6 2.5 phenylalanine transporter compare
BWI76_RS16815 +0.6 1.7 periplasmic binding protein compare
BWI76_RS15020 +0.6 2.3 2-oxobutyrate oxidase compare
BWI76_RS15035 +0.6 1.4 metal ABC transporter permease compare
BWI76_RS20325 +0.6 2.3 histidine/lysine/arginine/ornithine ABC transporter permease HisM compare
BWI76_RS09560 +0.6 1.2 DoxX family membrane protein compare
BWI76_RS00885 +0.6 1.6 tRNA (uridine(54)-C5)-methyltransferase TrmA compare
BWI76_RS25300 +0.6 1.7 hybrid sensor histidine kinase/response regulator compare
BWI76_RS01285 +0.6 2.6 amino acid ABC transporter substrate-binding protein compare
BWI76_RS26635 +0.6 2.8 hypothetical protein compare
BWI76_RS20775 +0.6 3.2 ethanolamine utilization protein EutH compare
BWI76_RS00710 +0.6 1.3 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS14980 +0.6 0.8 hypothetical protein compare
BWI76_RS02225 +0.6 2.0 phosphonate C-P lyase system protein PhnG compare
BWI76_RS21660 +0.6 1.3 antirestriction protein compare
BWI76_RS16975 +0.6 2.4 cysteine desufuration protein SufE compare
BWI76_RS09515 +0.6 2.0 arginine ABC transporter substrate-binding protein compare
BWI76_RS01140 +0.6 3.6 amino acid permease compare
BWI76_RS19575 +0.6 2.1 maleylacetoacetate isomerase compare
BWI76_RS04815 +0.6 1.1 cell division protein ZapD compare
BWI76_RS18455 +0.6 0.9 tRNA-Ser compare
BWI76_RS27825 +0.6 1.7 hypothetical protein compare
BWI76_RS14065 +0.6 0.6 hypothetical protein compare
BWI76_RS19890 +0.6 2.6 alpha-ketoglutarate-dependent dioxygenase AlkB compare
BWI76_RS17370 +0.6 1.3 nitrate transporter NasD compare
BWI76_RS02785 +0.6 2.6 AIG2 family protein compare
BWI76_RS12070 +0.6 0.8 hypothetical protein compare
BWI76_RS25980 +0.6 1.4 hypothetical protein compare
BWI76_RS12630 +0.6 2.4 regulatory protein, LysR:LysR, substrate-binding protein compare
BWI76_RS12460 +0.6 1.8 envelope stress response membrane protein PspC compare
BWI76_RS23130 +0.6 2.9 diol dehydratase reactivase subunit alpha compare
BWI76_RS19145 +0.6 1.3 formate dehydrogenase cytochrome b556 subunit compare
BWI76_RS02165 +0.6 3.0 D-allose transporter subunit compare
BWI76_RS02865 +0.6 2.4 hypothetical protein compare
BWI76_RS20885 +0.6 2.2 tRNA(Met) cytidine acetyltransferase TmcA compare
BWI76_RS25920 +0.6 0.7 peptidylprolyl isomerase compare
BWI76_RS10730 +0.6 1.2 bifunctional glucose-1-phosphatase/inositol phosphatase compare
BWI76_RS19275 +0.5 1.6 DNA-binding response regulator compare
BWI76_RS16495 +0.5 2.2 endopeptidase compare
BWI76_RS00095 +0.5 1.1 DNA-binding transcriptional regulator compare
BWI76_RS12185 +0.5 1.0 hypothetical protein compare
BWI76_RS26140 +0.5 1.1 GMP/IMP nucleotidase compare
BWI76_RS26330 +0.5 1.8 ABC transporter ATP-binding protein compare
BWI76_RS08885 +0.5 1.8 transcriptional regulator compare
BWI76_RS07475 +0.5 0.8 DNA-binding transcriptional regulator RamA compare
BWI76_RS15940 +0.5 0.8 DMSO reductase maturation protein DsmD compare
BWI76_RS21880 +0.5 2.2 agmatinase compare
BWI76_RS10680 +0.5 2.8 tartrate dehydrogenase compare
BWI76_RS18375 +0.5 2.2 hypothetical protein compare
BWI76_RS20465 +0.5 1.3 hypothetical protein compare
BWI76_RS21685 +0.5 1.0 hypothetical protein compare
BWI76_RS27900 +0.5 2.2 DNA damage-inducible protein D compare
BWI76_RS15350 +0.5 0.8 hypothetical protein compare
BWI76_RS22630 +0.5 1.8 LysR family transcriptional regulator compare
BWI76_RS12270 +0.5 1.1 hypothetical protein compare
BWI76_RS17765 +0.5 1.2 hypothetical protein compare
BWI76_RS16025 +0.5 1.3 triphosphoribosyl-dephospho-CoA synthase compare
BWI76_RS09625 +0.5 0.8 hypothetical protein compare
BWI76_RS05785 +0.5 1.6 CI repressor compare
BWI76_RS13400 +0.5 2.0 GntR family transcriptional regulator compare
BWI76_RS21780 +0.5 1.5 S-(hydroxymethyl)glutathione synthase compare
BWI76_RS04870 +0.5 2.5 aromatic amino acid transporter AroP compare
BWI76_RS12585 +0.5 1.6 transcriptional regulator compare
BWI76_RS06805 +0.5 1.6 primosomal replication protein N'' compare
BWI76_RS23390 +0.5 1.5 oligogalacturonide ABC transporter ATP-binding protein compare
BWI76_RS05410 +0.5 3.2 2,5-didehydrogluconate reductase B compare
BWI76_RS25480 +0.5 1.5 ribonuclease E/G compare
BWI76_RS18140 +0.5 1.7 zinc ABC transporter permease compare
BWI76_RS06465 +0.5 1.0 IclR family transcriptional regulator compare
BWI76_RS22850 +0.5 1.5 tRNA pseudouridine synthase TruC compare
BWI76_RS22125 +0.5 1.0 membrane protein compare
BWI76_RS10500 +0.5 0.8 flavoprotein monooxygenase compare
BWI76_RS10820 +0.5 1.3 iron uptake system protein EfeO compare
BWI76_RS07185 +0.5 0.5 hypothetical protein compare
BWI76_RS05965 +0.5 1.0 hypothetical protein compare
BWI76_RS08755 +0.5 1.8 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
BWI76_RS27635 +0.5 1.4 AraC family transcriptional regulator compare
BWI76_RS12040 +0.5 0.8 hypothetical protein compare
BWI76_RS09295 +0.5 1.3 hypothetical protein compare
BWI76_RS22620 +0.5 1.1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase compare
BWI76_RS00995 +0.5 2.1 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS01925 +0.5 2.8 aromatic amino acid aminotransferase compare
BWI76_RS27850 +0.5 1.5 DNA-binding transcriptional regulator DsdC compare
BWI76_RS18060 +0.5 1.0 hypothetical protein compare
BWI76_RS06935 +0.5 2.0 co-chaperone YbbN compare
BWI76_RS19390 +0.5 2.1 LysR family transcriptional regulator compare
BWI76_RS11605 +0.5 1.7 DNA topoisomerase III compare
BWI76_RS05570 +0.5 0.7 hypothetical protein compare
BWI76_RS15950 +0.5 1.1 dethiobiotin synthase compare
BWI76_RS21955 +0.5 3.0 transferase compare
BWI76_RS19725 +0.5 2.1 PTS fructose transporter subunit EIIBC compare
BWI76_RS18550 +0.5 1.0 tRNA-Asn compare
BWI76_RS26660 +0.5 2.0 transcription elongation factor GreB compare
BWI76_RS20750 +0.5 0.8 carboxysome structural protein EutK compare
BWI76_RS20310 +0.5 1.6 hypothetical protein compare
BWI76_RS03285 +0.5 1.8 hypothetical protein compare
BWI76_RS12170 +0.5 1.8 hypothetical protein compare
BWI76_RS23080 +0.5 1.9 precorrin-8X methylmutase compare
BWI76_RS15785 +0.5 2.3 replication protein compare
BWI76_RS06745 +0.5 0.8 N-acetyltransferase GCN5 compare
BWI76_RS09875 +0.5 2.7 phosphoporin PhoE compare
BWI76_RS24505 +0.5 2.1 urease subunit beta compare
BWI76_RS14975 +0.5 2.1 glyoxalase-like domain protein compare
BWI76_RS08770 +0.5 1.8 malonyl-ACP O-methyltransferase BioC compare
BWI76_RS17945 +0.5 0.8 hypothetical protein compare
BWI76_RS13090 +0.5 1.2 phenylacetate-CoA oxygenase subunit PaaA compare
BWI76_RS09310 +0.5 1.4 hypothetical protein compare
BWI76_RS14675 +0.5 1.5 fimbrial chaperone YfcS compare
BWI76_RS24080 +0.5 0.4 DUF179 domain-containing protein compare
BWI76_RS03410 +0.5 2.2 hypothetical protein compare
BWI76_RS20605 +0.5 1.6 purine-nucleoside phosphorylase compare
BWI76_RS22235 +0.5 1.4 transcriptional regulator GutM compare
BWI76_RS16480 +0.5 2.3 lactoylglutathione lyase compare
BWI76_RS15340 +0.5 1.5 urea ABC transporter substrate-binding protein compare
BWI76_RS10850 +0.5 2.4 two-component sensor histidine kinase compare
BWI76_RS21040 +0.5 1.7 peptidase M4 compare
BWI76_RS06120 +0.5 1.3 membrane protein compare
BWI76_RS06440 +0.5 1.6 AP endonuclease compare
BWI76_RS15190 +0.5 1.7 GGDEF domain-containing protein compare
BWI76_RS16000 +0.5 0.7 multidrug transporter subunit MdtI compare
BWI76_RS17510 +0.4 1.7 selenium metabolism hydrolase compare
BWI76_RS08745 +0.4 1.4 proline-specific permease compare
BWI76_RS24585 +0.4 1.0 glycerol dehydrogenase compare
BWI76_RS14000 +0.4 1.9 glutamine amidotransferase compare
BWI76_RS01335 +0.4 2.3 DNase TatD compare
BWI76_RS08750 +0.4 0.7 kinase inhibitor compare
BWI76_RS17525 +0.4 1.1 XshC-Cox1-family protein compare
BWI76_RS11825 +0.4 1.4 LysR family transcriptional regulator compare
BWI76_RS15345 +0.4 1.3 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS15195 +0.4 1.0 DUF4186 domain-containing protein compare
BWI76_RS08005 +0.4 2.4 transcriptional regulator compare
BWI76_RS21850 +0.4 1.6 AraC family transcriptional regulator compare
BWI76_RS24105 +0.4 2.3 resistance protein compare
BWI76_RS10260 +0.4 1.7 creatinase compare
BWI76_RS22365 +0.4 1.4 hydrogenase expression/formation protein HypE compare


Specific Phenotypes

For 7 genes in this experiment

For nitrogen source L-Histidine in Klebsiella michiganensis M5al

For nitrogen source L-Histidine across organisms