Experiment set6IT034 for Pseudomonas fluorescens FW300-N2E2

Compare to:

LB with 4-Hydroxyacetophenone 0.00025 M

200 most detrimental genes:

  gene name fitness t score description  
Pf6N2E2_2823 +9.6 44.0 Multidrug efflux RND membrane fusion protein MexC compare
Pf6N2E2_2824 +9.0 60.1 RND efflux system, inner membrane transporter CmeB compare
Pf6N2E2_2825 +4.5 19.4 RND efflux system, outer membrane lipoprotein CmeC compare
Pf6N2E2_3663 +2.9 16.1 Glycosyl transferase compare
Pf6N2E2_5534 +2.5 14.0 FIG000859: hypothetical protein YebC compare
Pf6N2E2_3351 +2.0 7.2 tRNA pseudouridine synthase B (EC 4.2.1.70) compare
Pf6N2E2_3261 +1.6 6.1 hypothetical protein compare
Pf6N2E2_2967 +1.6 3.0 Cold shock protein CspA compare
Pf6N2E2_3763 +1.6 3.0 hypothetical protein compare
Pf6N2E2_288 +1.3 2.9 Isocitrate dehydrogenase [NADP] (EC 1.1.1.42); Monomeric isocitrate dehydrogenase [NADP] (EC 1.1.1.42) compare
Pf6N2E2_1886 +1.2 2.3 hypothetical protein compare
Pf6N2E2_1032 +1.1 1.5 Alkanesulfonates ABC transporter ATP-binding protein / Sulfonate ABC transporter, ATP-binding subunit SsuB compare
Pf6N2E2_754 +1.1 2.3 Histone acetyltransferase HPA2 and related acetyltransferases compare
Pf6N2E2_2420 +1.1 2.0 hypothetical protein compare
Pf6N2E2_1917 +1.1 2.7 hypothetical protein compare
Pf6N2E2_463 +1.1 6.1 Transcriptional regulatory protein RstA compare
Pf6N2E2_3475 +1.1 2.1 hypothetical protein compare
Pf6N2E2_6065 +1.0 1.2 ABC transporter in pyoverdin gene cluster, periplasmic component compare
Pf6N2E2_5374 +1.0 1.7 Membrane fusion component of tripartite multidrug resistance system compare
Pf6N2E2_2323 +1.0 2.6 Fumarate and nitrate reduction regulatory protein compare
Pf6N2E2_4579 +1.0 1.3 Ribosomal RNA small subunit methyltransferase D (EC 2.1.1.-) compare
Pf6N2E2_204 +1.0 0.9 hypothetical protein compare
Pf6N2E2_5862 +1.0 2.1 Lipoprotein, putative compare
Pf6N2E2_4766 +1.0 7.9 Acyl-CoA dehydrogenase (EC 1.3.8.7) compare
Pf6N2E2_469 +1.0 1.8 lipoprotein, putative compare
Pf6N2E2_1676 +0.9 1.5 conserved protein associated with acetyl-CoA C-acyltransferase compare
Pf6N2E2_952 +0.9 2.3 putative exported protein compare
Pf6N2E2_5794 +0.9 2.3 Ribosomal large subunit pseudouridine synthase A (EC 4.2.1.70) compare
Pf6N2E2_241 +0.9 1.5 hypothetical protein compare
Pf6N2E2_309 +0.9 1.2 FIG00957702: hypothetical protein compare
Pf6N2E2_1347 +0.9 2.1 Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-) compare
Pf6N2E2_1824 +0.9 1.5 hypothetical protein compare
Pf6N2E2_2440 +0.9 1.4 Free methionine-(R)-sulfoxide reductase, contains GAF domain compare
Pf6N2E2_4422 +0.9 3.0 Frataxin homolog CyaY, facilitates iron supply for heme A synthesis or Fe-S cluster assembly compare
Pf6N2E2_4152 +0.9 5.0 alginate biosynthesis transcriptional regulatory protein AlgB compare
Pf6N2E2_4160 +0.8 1.3 Cytochrome c5 compare
Pf6N2E2_2433 +0.8 1.2 Probable transmembrane protein compare
Pf6N2E2_3947 +0.8 1.3 Cd(II)/Pb(II)-responsive transcriptional regulator compare
Pf6N2E2_5720 +0.8 6.0 BarA sensory histidine kinase (= VarS = GacS) compare
Pf6N2E2_6099 +0.8 1.2 tRNA-Glu-TTC compare
Pf6N2E2_1040 +0.8 1.1 Hydroxymethylglutaryl-CoA lyase (EC 4.1.3.4) compare
Pf6N2E2_2480 +0.8 1.6 FIG00957636: hypothetical protein compare
Pf6N2E2_3875 +0.8 1.3 FIG00953324: hypothetical protein compare
Pf6N2E2_4928 +0.8 1.5 Permeases of the major facilitator superfamily compare
Pf6N2E2_1339 +0.8 2.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_180 +0.8 1.9 Transcriptional regulator, MerR family compare
Pf6N2E2_1549 +0.8 3.1 Transcriptional regulator, LysR family compare
Pf6N2E2_1118 +0.8 1.7 FIG054297: Transcriptional regulator, AraC family compare
Pf6N2E2_2055 +0.8 2.5 StbE replicon stabilization toxin compare
Pf6N2E2_16 +0.8 1.3 hypothetical protein compare
Pf6N2E2_4362 +0.8 2.4 DNA-directed RNA polymerase omega subunit (EC 2.7.7.6) compare
Pf6N2E2_3762 +0.8 3.6 NADP-dependent malic enzyme (EC 1.1.1.40) compare
Pf6N2E2_2750 +0.8 4.5 Putative permease PerM (= YfgO) compare
Pf6N2E2_2350 +0.8 2.3 Oxygen-regulated invasion protein OrgB compare
Pf6N2E2_3870 +0.8 1.1 hypothetical protein compare
Pf6N2E2_687 +0.8 1.7 4-oxalocrotonate tautomerase (EC 5.3.2.-) compare
Pf6N2E2_5243 +0.8 2.0 hypothetical protein compare
Pf6N2E2_2962 +0.8 2.6 ABC transporter for L-Lysine, ATPase component (from data) compare
Pf6N2E2_4581 +0.8 3.2 FIG015547: peptidase, M16 family compare
Pf6N2E2_3122 +0.8 2.0 Chemotaxis signal transduction protein compare
Pf6N2E2_4478 +0.8 4.5 FIG019278: hypothetical protein compare
Pf6N2E2_2827 +0.7 0.6 hypothetical protein compare
Pf6N2E2_1504 +0.7 1.5 putative 2-pyrone-4,6-dicarboxylic acid hydrolase compare
Pf6N2E2_3543 +0.7 4.4 Uncharacterized iron-regulated membrane protein; Iron-uptake factor PiuB compare
Pf6N2E2_5158 +0.7 1.8 FIG00954153: hypothetical protein compare
Pf6N2E2_4353 +0.7 3.4 Hydrogen peroxide-inducible genes activator compare
Pf6N2E2_1460 +0.7 2.1 Epoxide hydrolase (EC 3.3.2.9) compare
Pf6N2E2_2065 +0.7 2.0 Cobalt-precorrin-4 C11-methyltransferase (EC 2.1.1.133) compare
Pf6N2E2_4635 +0.7 4.6 ATP-dependent RNA helicase RhlE compare
Pf6N2E2_3588 +0.7 2.4 hypothetical protein compare
Pf6N2E2_82 +0.7 1.2 hypothetical protein compare
Pf6N2E2_2286 +0.7 1.5 FIG00953287: hypothetical protein compare
Pf6N2E2_620 +0.7 3.5 BatD compare
Pf6N2E2_425 +0.7 2.4 FIG00957304: hypothetical protein compare
Pf6N2E2_4624 +0.7 0.8 Phosphoribosyl-dephospho-CoA transferase (EC 2.7.7.-) compare
Pf6N2E2_2273 +0.7 2.4 Glycerophosphoryl diester phosphodiesterase (EC 3.1.4.46) compare
Pf6N2E2_1148 +0.7 2.0 Butyryl-CoA dehydrogenase (EC 1.3.99.2) compare
Pf6N2E2_1445 +0.7 1.2 Glutathione S-transferase compare
Pf6N2E2_3899 +0.7 4.8 Phosphoenolpyruvate carboxykinase [ATP] (EC 4.1.1.49) compare
Pf6N2E2_1987 +0.7 1.4 hypothetical protein compare
Pf6N2E2_367 +0.7 2.1 Acetylornithine deacetylase (EC 3.5.1.16) compare
Pf6N2E2_2373 +0.7 1.1 Type III secretion thermoregulatory protein (LcrF,VirF,transcription regulation of virulence plasmid) compare
Pf6N2E2_724 +0.7 1.5 Nitric oxide -responding transcriptional regulator Dnr (Crp/Fnr family) compare
Pf6N2E2_2806 +0.7 1.8 Methyltransferase (EC 2.1.1.-) compare
Pf6N2E2_2017 +0.7 2.0 DNA-binding protein compare
Pf6N2E2_3656 +0.7 3.4 Probable transcription regulator Mig-14 compare
Pf6N2E2_621 +0.7 2.7 TPR domain protein in aerotolerance operon compare
Pf6N2E2_3255 +0.7 2.4 YrbA protein compare
Pf6N2E2_1981 +0.7 2.7 FIG051360: Periplasmic protein TonB, links inner and outer membranes compare
Pf6N2E2_5736 +0.7 2.6 FIG00961250: hypothetical protein compare
Pf6N2E2_4418 +0.7 0.8 Diaminopimelate epimerase (EC 5.1.1.7) compare
Pf6N2E2_4710 +0.7 1.6 hypothetical protein compare
Pf6N2E2_304 +0.7 2.1 Anthranilate phosphoribosyltransferase like (EC 2.4.2.18) compare
Pf6N2E2_2674 +0.7 0.9 FIG00953856: hypothetical protein compare
Pf6N2E2_865 +0.6 1.5 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_988 +0.6 1.7 4-hydroxyphenylpyruvate dioxygenase (EC 1.13.11.27) compare
Pf6N2E2_2995 +0.6 2.9 FIG00959768: hypothetical protein compare
Pf6N2E2_5545 +0.6 2.3 Queuosine Biosynthesis QueE Radical SAM compare
Pf6N2E2_4749 +0.6 2.3 DNA polymerase III epsilon subunit (EC 2.7.7.7) compare
Pf6N2E2_1293 +0.6 1.7 COG2879, Hypothetical small protein yjiX compare
Pf6N2E2_5625 +0.6 3.0 COG0613, Predicted metal-dependent phosphoesterases (PHP family) compare
Pf6N2E2_464 +0.6 1.6 Sensory histidine kinase QseC compare
Pf6N2E2_5499 +0.6 0.9 hypothetical protein compare
Pf6N2E2_1366 +0.6 2.5 FIG002465: BNR repeat protein compare
Pf6N2E2_1317 +0.6 1.5 P-hydroxyphenylacetate hydroxylase C2:oxygenase component compare
Pf6N2E2_2022 +0.6 2.9 BarA-associated response regulator UvrY (= GacA = SirA) compare
Pf6N2E2_623 +0.6 1.0 FIG00954674: hypothetical protein compare
Pf6N2E2_913 +0.6 2.1 FIG00958137: hypothetical protein compare
Pf6N2E2_1512 +0.6 1.6 Thiamin biosynthesis lipoprotein ApbE compare
Pf6N2E2_639 +0.6 2.0 FIG01285020: hypothetical protein compare
Pf6N2E2_1398 +0.6 2.4 Rhodanese-related sulfurtransferase compare
Pf6N2E2_2121 +0.6 0.8 hypothetical protein compare
Pf6N2E2_4415 +0.6 1.6 Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase compare
Pf6N2E2_3986 +0.6 2.2 PROBABLE REMNANT OF A TRANSPOSASE GENE PROTEIN compare
Pf6N2E2_2885 +0.6 2.6 Glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) compare
Pf6N2E2_1441 +0.6 1.2 Uncharacterized oxidoreductase ydgJ (EC 1.-.-.-) compare
Pf6N2E2_238 +0.6 1.3 hypothetical protein compare
Pf6N2E2_5455 +0.6 2.0 hypothetical protein compare
Pf6N2E2_1666 +0.6 2.0 Transcriptional regulator, LysR family compare
Pf6N2E2_84 +0.6 1.0 hypothetical protein compare
Pf6N2E2_5411 +0.6 2.3 FIG00955494: hypothetical protein compare
Pf6N2E2_1667 +0.6 1.6 Fumarylacetoacetate hydrolase family protein compare
Pf6N2E2_5776 +0.6 2.2 hypothetical protein compare
Pf6N2E2_1288 +0.6 0.9 Protein containing transglutaminase-like domain, putative cysteine protease compare
Pf6N2E2_5525 +0.6 4.4 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases compare
Pf6N2E2_641 +0.6 2.5 Extracytoplasmic function (ECF) sigma factor VreI compare
Pf6N2E2_1113 +0.6 1.2 Transcriptional regulator, TetR family compare
Pf6N2E2_2930 +0.6 1.9 INTEGRAL MEMBRANE PROTEIN (Rhomboid family) compare
Pf6N2E2_442 +0.6 1.8 FIG00962345: hypothetical protein compare
Pf6N2E2_5842 +0.6 2.0 Transcriptional regulator, TetR family compare
Pf6N2E2_3597 +0.6 2.4 hypothetical protein compare
Pf6N2E2_391 +0.6 2.1 hypothetical protein compare
Pf6N2E2_5869 +0.6 1.6 Helicase subunit of the DNA excision repair complex compare
Pf6N2E2_2390 +0.6 1.6 FIG00959101: hypothetical protein compare
Pf6N2E2_1654 +0.6 1.1 Oxidoreductase, short chain dehydrogenase/reductase family compare
Pf6N2E2_3192 +0.6 1.7 tRNA:Cm32/Um32 methyltransferase compare
Pf6N2E2_672 +0.6 1.6 ABC-type polar amino acid transport system, ATPase component compare
Pf6N2E2_5609 +0.6 3.0 DNA-binding response regulator ColR compare
Pf6N2E2_1385 +0.6 1.5 FIG00956261: hypothetical protein compare
Pf6N2E2_1613 +0.6 1.5 short-chain dehydrogenase/reductase compare
Pf6N2E2_5261 +0.6 0.8 FIG00956983: hypothetical protein compare
Pf6N2E2_1162 +0.6 0.9 Transmembrane amino acid efflux protein compare
Pf6N2E2_4548 +0.6 0.7 hypothetical protein compare
Pf6N2E2_1997 +0.6 1.8 FIG00956406: hypothetical protein compare
Pf6N2E2_89 +0.5 1.1 hypothetical protein compare
Pf6N2E2_942 +0.5 0.8 Mll6465 protein compare
Pf6N2E2_5877 +0.5 1.1 Phosphohistidine phosphatase SixA compare
Pf6N2E2_1712 +0.5 1.8 Permease of the drug/metabolite transporter (DMT) superfamily compare
Pf6N2E2_1607 +0.5 1.9 Exopolyphosphatase (EC 3.6.1.11) compare
Pf6N2E2_659 +0.5 0.7 Transcriptional regulatory protein ompR compare
Pf6N2E2_4543 +0.5 1.3 hypothetical protein compare
Pf6N2E2_755 +0.5 3.7 UPF0141 membrane protein YijP possibly required for phosphoethanolamine modification of lipopolysaccharide compare
Pf6N2E2_1718 +0.5 1.2 Anthranilate synthase, amidotransferase component (EC 4.1.3.27) compare
Pf6N2E2_1776 +0.5 1.2 Chemotaxis protein CheD compare
Pf6N2E2_1116 +0.5 1.0 Inosine-5'-monophosphate dehydrogenase (EC 1.1.1.205) compare
Pf6N2E2_961 +0.5 1.1 FIG00954712: hypothetical protein compare
Pf6N2E2_2296 +0.5 1.5 FIG00954767: hypothetical protein compare
Pf6N2E2_953 +0.5 0.7 FIG00958851: hypothetical protein compare
Pf6N2E2_967 +0.5 1.7 DNA repair protein RadC compare
Pf6N2E2_1516 +0.5 1.9 transcriptional regulator, Crp/Fnr family compare
Pf6N2E2_1049 +0.5 1.8 hypothetical protein compare
Pf6N2E2_3155 +0.5 2.0 Phosphonate ABC transporter phosphate-binding periplasmic component (TC 3.A.1.9.1) compare
Pf6N2E2_2663 +0.5 1.4 FIG00953341: hypothetical protein compare
Pf6N2E2_2262 +0.5 1.6 Phosphonoacetaldehyde phosphonohydrolase-related protein compare
Pf6N2E2_2879 +0.5 1.8 membrane protein, putative compare
Pf6N2E2_3339 +0.5 3.0 Phosphoenolpyruvate-protein phosphotransferase of PTS system (EC 2.7.3.9) compare
Pf6N2E2_5240 +0.5 2.7 FIG00953775: hypothetical protein compare
Pf6N2E2_58 +0.5 0.6 tRNA-dihydrouridine synthase C (EC 1.-.-.-) compare
Pf6N2E2_1548 +0.5 1.5 Lactoylglutathione lyase compare
Pf6N2E2_706 +0.5 2.5 Nitric oxide reductase activation protein NorQ compare
Pf6N2E2_1435 +0.5 1.3 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases; sulfonate monooxygenase compare
Pf6N2E2_3516 +0.5 1.1 Probable transmembrane protein compare
Pf6N2E2_403 +0.5 1.6 Cyanate hydratase (EC 4.2.1.104) compare
Pf6N2E2_1498 +0.5 2.1 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain compare
Pf6N2E2_3788 +0.5 2.5 Methyl-accepting chemotaxis protein I (serine chemoreceptor protein) compare
Pf6N2E2_857 +0.5 2.3 hypothetical protein compare
Pf6N2E2_681 +0.5 2.0 4-hydroxyproline epimerase (EC 5.1.1.8) compare
Pf6N2E2_3916 +0.5 2.1 Short-chain dehydrogenase/reductase SDR compare
Pf6N2E2_1476 +0.5 1.3 (AF179595) Vco33 compare
Pf6N2E2_5695 +0.5 2.9 Flagellar basal-body rod protein FlgC compare
Pf6N2E2_361 +0.5 1.5 Peptide ABC transporter, permease protein compare
Pf6N2E2_6035 +0.5 1.2 alpha/beta hydrolase fold compare
Pf6N2E2_2089 +0.5 1.5 Transcriptional regulator, AraC family compare
Pf6N2E2_1735 +0.5 0.9 PhnB protein compare
Pf6N2E2_2069 +0.5 0.9 FIG00953703: hypothetical protein compare
Pf6N2E2_5531 +0.5 1.7 hypothetical protein compare
Pf6N2E2_5910 +0.5 1.2 Flp pilus assembly protein RcpC/CpaB compare
Pf6N2E2_2646 +0.5 0.9 FIG00953416: hypothetical protein compare
Pf6N2E2_314 +0.5 1.4 Isochorismatase (EC 3.3.2.1) compare
Pf6N2E2_1252 +0.5 2.5 Catalase (EC 1.11.1.6) compare
Pf6N2E2_1466 +0.5 2.3 NAD-dependent formate dehydrogenase delta subunit compare
Pf6N2E2_1499 +0.5 1.3 ABC transporter amino acid-binding protein compare
Pf6N2E2_5785 +0.5 1.1 Phosphoserine phosphatase (EC 3.1.3.3) compare
Pf6N2E2_1440 +0.5 1.5 Putative tRNA-m1A22 methylase compare
Pf6N2E2_2765 +0.5 2.0 Tricarboxylate transport transcriptional regulator TctD compare
Pf6N2E2_897 +0.5 2.0 Maleate cis-trans isomerase (EC 5.2.1.1) compare
Pf6N2E2_3003 +0.5 0.6 Bacteriophage protein GP46 compare
Pf6N2E2_4332 +0.5 2.3 hypothetical protein compare
Pf6N2E2_750 +0.5 1.0 Transcriptional regulator, DeoR family compare
Pf6N2E2_715 +0.5 1.7 putative membrane protein compare


Specific Phenotypes

For 1 genes in this experiment

For stress 4-Hydroxyacetophenone in Pseudomonas fluorescens FW300-N2E2

For stress 4-Hydroxyacetophenone across organisms