Experiment set6IT032 for Marinobacter adhaerens HP15

Compare to:

marine broth with Cisplatin 0.025 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
HP15_3544 +7.8 39.9 transcriptional regulator, GntR family compare
HP15_1655 +6.7 6.3 transcriptional regulator, TetR family compare
HP15_675 +4.9 20.8 conserved hypothetical protein compare
HP15_328 +4.1 3.4 two component, sigma54 specific, transcriptional regulator, Fis family compare
HP15_676 +3.6 16.4 N-acetylmuramoyl-L-alanine amidase compare
HP15_678 +3.2 10.8 conserved hypothetical protein compare
HP15_1606 +3.2 9.6 general secretion pathway protein I-like protein compare
HP15_p42g33 +3.1 15.7 protein containing resolvase N-terminal domain compare
HP15_2442 +3.0 14.8 RNA polymerase, sigma 54 subunit, RpoN compare
HP15_755 +3.0 16.0 Mg2+ and Co2+ transporter CorB compare
HP15_1650 +2.9 3.8 iron-sulfur cluster-binding protein-like protein compare
HP15_2534 +2.9 3.1 hypothetical protein compare
HP15_455 +2.9 2.9 protein containing DUF1249 compare
HP15_677 +2.8 7.7 hypothetical protein compare
HP15_2972 +2.6 3.0 cyclic nucleotide-binding protein compare
HP15_1781 +2.6 2.5 beta-lactamase hydrolase-like protein compare
HP15_541 +2.5 10.4 peptide chain release factor 3 compare
HP15_3278 +2.2 7.6 dimethyladenosine transferase compare
HP15_337 +2.2 1.7 hypothetical protein compare
HP15_3059 +2.2 5.0 high-affinity branched-chain amino acid ABC transporter, ATP-binding protein compare
HP15_674 +2.1 8.7 phage-related packaging protein compare
HP15_329 +2.1 5.7 two-component sensor compare
HP15_3628 +2.1 1.2 hypothetical protein compare
HP15_666 +2.1 9.9 conserved hypothetical protein compare
HP15_3055 +2.0 14.1 high-affinity leucine-specific leucine-specific-binding periplasmic protein of high-affinity branched-chain amino acid ABC transporter transport system periplasmic binding protein compare
HP15_2470 +2.0 6.5 metal ion transporter compare
HP15_743 +2.0 1.8 hypothetical protein compare
HP15_655 +2.0 4.7 phage tail collar domain protein-like protein compare
HP15_2167 +2.0 6.5 transcriptional repressor for the dissimilation of sn-glycerol 3-phosphate, DeoR family protein compare
HP15_3057 +2.0 14.2 leucine/isoleucine/valine transporter permease subunit compare
HP15_1985 +1.9 6.8 protein containing phage antirepressor protein domain compare
HP15_663 +1.9 13.1 phage baseplate assembly protein compare
HP15_2585 +1.9 4.6 multiple resistance and pH regulation protein F compare
HP15_3058 +1.9 11.0 leucine/isoleucine/valine transporter ATP-binding subunit compare
HP15_656 +1.9 6.5 tail fiber assembly protein-like protein compare
HP15_660 +1.9 3.9 hypothetical protein compare
HP15_657 +1.9 11.8 phage tail fiber protein compare
HP15_3056 +1.8 10.8 high-affinity branched-chain amino acid ABC transporter, permease protein compare
HP15_673 +1.8 10.8 phage terminase GpA compare
HP15_3261 +1.8 10.3 efflux transporter, RND family, MFP subunit compare
HP15_667 +1.8 8.3 prophage LambdaW5, minor tail protein Z-like protein compare
HP15_1974 +1.8 6.5 hypothetical protein compare
HP15_672 +1.8 9.8 conserved hypothetical protein compare
HP15_670 +1.7 13.0 peptidase U35, phage prohead compare
HP15_662 +1.7 6.7 phage tail protein I compare
HP15_3262 +1.7 14.3 multidrug resistance protein compare
HP15_2698 +1.7 1.4 phenylacetate-CoA oxygenase, PaaH subunit compare
HP15_603 +1.7 4.0 Iojap-related protein compare
HP15_665 +1.7 10.7 phage-related baseplate assembly protein V compare
HP15_664 +1.7 6.1 GPW/gp25 compare
HP15_44 +1.7 5.0 DitK protein compare
HP15_2663 +1.7 3.1 response regulator receiver and unknown domain protein compare
HP15_659 +1.7 7.8 hypothetical protein compare
HP15_669 +1.7 8.0 protein containing Rho termination factor, N-terminal domain compare
HP15_686 +1.7 8.3 conserved hypothetical protein compare
HP15_661 +1.7 9.0 hypothetical protein compare
HP15_2899 +1.6 7.6 rhodanese sulfurtransferase compare
HP15_654 +1.6 10.6 major tail sheath protein compare
HP15_671 +1.6 9.4 phage portal protein, lambda family compare
HP15_3184 +1.6 13.8 two-component system sensor protein compare
HP15_2528 +1.6 1.5 hypothetical protein compare
HP15_658 +1.6 13.1 secreted protein-putative xanthan lyase compare
HP15_228 +1.6 9.4 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
HP15_2559 +1.5 9.6 membrane protein containing DUF6, transmembrane compare
HP15_1973 +1.5 2.7 hypothetical protein compare
HP15_1016 +1.5 2.3 acetolactate synthase II, small subunit-like protein compare
HP15_651 +1.5 10.5 protein putative phage tail tape measure protein-like protein compare
HP15_2582 +1.5 3.4 NADH-ubiquinone oxidoreductase, chain 4L compare
HP15_2583 +1.5 6.5 monovalent cation/H+ antiporter subunit D compare
HP15_1990 +1.5 7.5 hypothetical protein compare
HP15_1991 +1.5 3.4 conserved hypothetical protein compare
HP15_1215 +1.5 1.5 ribonuclease T compare
HP15_650 +1.5 7.0 phage P2 GpU compare
HP15_701 +1.5 1.7 hypothetical protein compare
HP15_3003 +1.5 4.2 protein-export protein SecB compare
HP15_704 +1.5 5.1 translation-associated GTPase compare
HP15_1047 +1.5 10.1 DNA mismatch repair protein MutS compare
HP15_2008 +1.4 2.7 conserved hypothetical protein compare
HP15_2558 +1.4 1.4 putative nuclease compare
HP15_687 +1.4 8.1 protein containing domain of unknown function DUF1994 compare
HP15_2581 +1.4 7.7 monovalent cation/H+ antiporter subunit A compare
HP15_549 +1.4 3.4 stringent starvation protein B compare
HP15_3811 +1.4 1.0 conserved hypothetical protein compare
HP15_653 +1.4 5.6 phage major tail tube protein compare
HP15_668 +1.4 4.9 conserved hypothetical protein compare
HP15_1992 +1.3 5.0 conserved hypothetical protein compare
HP15_1529 +1.3 1.5 transcriptional regulator compare
HP15_3185 +1.3 8.5 conserved hypothetical protein containing DUF1745 compare
HP15_2621 +1.3 1.5 branched-chain amino acid transport compare
HP15_3203 +1.3 7.2 proline aminopeptidase P II compare
HP15_273 +1.3 5.6 spermidine synthase compare
HP15_272 +1.3 9.3 biosynthetic arginine decarboxylase compare
HP15_1951 +1.3 4.7 hypothetical protein compare
HP15_3004 +1.3 4.1 rhodanese domain protein compare
HP15_2586 +1.3 5.2 monovalent cation/H+ antiporter subunit G compare
HP15_1157 +1.3 5.0 cold-shock DNA-binding domain protein compare
HP15_648 +1.3 8.9 phage late control D compare
HP15_3515 +1.3 3.3 chemotaxis signal transduction protein compare
HP15_2467 +1.3 2.6 PhoH family protein compare
HP15_1969 +1.3 3.3 hypothetical protein compare
HP15_1236 +1.3 8.5 conserved hypothetical protein compare
HP15_692 +1.3 4.8 phage protein compare
HP15_695 +1.3 1.8 conserved hypothetical protein compare
HP15_2450 +1.3 9.1 conserved hypothetical protein compare
HP15_3603 +1.2 4.4 transcriptional regulator, HxlR family compare
HP15_1337 +1.2 0.9 conserved hypothetical protein, membrane compare
HP15_3821 +1.2 2.9 transcriptional regulator, MarR family compare
HP15_1625 +1.2 4.3 3-oxoacyl-(acyl carrier protein) synthase III compare
HP15_679 +1.2 3.6 conserved hypothetical protein compare
HP15_3037 +1.2 5.4 transcriptional regulator, TetR family protein compare
HP15_2263 +1.2 1.5 conserved hypothetical protein, membrane compare
HP15_3044 +1.2 5.2 conserved hypothetical protein, secreted compare
HP15_1966 +1.2 1.1 head-to-tail joining protein W, GpW compare
HP15_2417 +1.2 1.7 YfaZ family protein compare
HP15_1988 +1.2 5.5 hypothetical protein compare
HP15_649 +1.2 2.9 phage tail protein X compare
HP15_2584 +1.2 2.5 pH adaption potassium efflux system protein PhaE compare
HP15_3374 +1.2 5.2 protein CrcB-like protein compare
HP15_2493 +1.2 1.8 methyltransferase compare
HP15_1490 +1.2 3.6 conserved hypothetical protein compare
HP15_4077 +1.2 1.7 conserved hypothetical protein compare
HP15_2569 +1.1 2.0 conserved hypothetical protein, membrane compare
HP15_1976 +1.1 6.0 hypothetical protein compare
HP15_3111 +1.1 2.6 hypothetical protein compare
HP15_2922 +1.1 1.1 hypothetical protein compare
HP15_2262 +1.1 1.2 transcriptional Regulator, TetR family protein compare
HP15_2116 +1.1 1.0 PP-loop domain protein compare
HP15_1971 +1.1 4.6 hypothetical protein compare
HP15_1972 +1.1 6.1 fibronectin, type III domain protein-like protein compare
HP15_2469 +1.1 1.0 predicted metal-dependent hydrolase compare
HP15_1626 +1.1 0.8 conserved hypothetical protein compare
HP15_330 +1.1 4.7 conserved hypothetical protein, membrane compare
HP15_684 +1.1 2.1 hypothetical protein compare
HP15_2160 +1.1 2.6 transmembrane protein compare
HP15_2190 +1.1 3.1 peptidyl-prolyl cis-trans isomerase B compare
HP15_2183 +1.1 7.3 DNA-binding ATP-dependent protease La compare
HP15_909 +1.1 5.2 enoyl-CoA hydratase/isomerase family protein compare
HP15_1959 +1.1 5.2 conserved hypothetical protein compare
HP15_788 +1.1 7.6 multi-sensor hybrid histidine kinase compare
HP15_3481 +1.1 1.8 transcription elongation factor GreB compare
HP15_2002 +1.1 2.3 conserved hypothetical protein compare
HP15_205 +1.1 5.8 protein containing bacterial regulatory protein, LysR domain compare
HP15_699 +1.1 6.8 conserved hypothetical protein compare
HP15_204 +1.1 6.7 oligopeptide/dipeptide ABC transporter, ATPase subunit compare
HP15_3204 +1.1 2.1 yecA family protein compare
HP15_2596 +1.1 1.0 endoribonuclease L-PSP compare
HP15_p42g14 +1.0 1.2 hypothetical protein compare
HP15_3317 +1.0 1.3 acetylglutamate kinase compare
HP15_1261 +1.0 1.3 acireductone dioxygenase, ARD compare
HP15_1263 +1.0 1.8 conserved hypothetical protein compare
HP15_693 +1.0 2.7 hypothetical protein compare
HP15_697 +1.0 2.1 conserved hypothetical protein compare
HP15_2180 +1.0 6.3 transcriptional regulator, RpiR family protein compare
HP15_3510 +1.0 1.6 transcriptional regulator compare
HP15_p42g17 +1.0 6.4 traN-like protein compare
HP15_2661 +1.0 2.4 Citrate uptake transporter, substrate-binding component TctC (from data) compare
HP15_1963 +1.0 4.0 conserved hypothetical protein compare
HP15_1983 +1.0 5.3 hypothetical protein compare
HP15_652 +1.0 1.5 conserved hypothetical protein compare
HP15_1970 +1.0 6.4 hypothetical protein compare
HP15_3787 +1.0 6.5 L-ectoine synthase compare
HP15_201 +1.0 4.5 peptide transport system permease ABC transporter protein compare
HP15_1247 +1.0 2.0 signal transduction histidine kinase compare
HP15_1193 +1.0 1.4 conserved hypothetical protein compare
HP15_4105 +1.0 2.4 hypothetical protein compare
HP15_604 +1.0 2.7 conserved hypothetical protein CHP00246 compare
HP15_2220 +0.9 1.7 HAD-superfamily hydrolase, subfamily IA, variant 3 compare
HP15_907 +0.9 5.0 acyl-CoA dehydrogenase domain protein compare
HP15_1241 +0.9 5.2 ADP-ribose pyrophosphatase compare
HP15_2448 +0.9 0.8 protein belonging to uncharacterized protein family UPF0307 compare
HP15_3277 +0.9 2.8 diadenosine tetraphosphatase compare
HP15_2348 +0.9 1.6 conserved hypothetical protein compare
HP15_2306 +0.9 3.1 uracil phosphoribosyltransferase compare
HP15_p42g45 +0.9 4.6 conjugation TrbI family protein compare
HP15_1465 +0.9 3.2 conserved hypothetical protein, membrane compare
HP15_4176 +0.9 2.2 electron-transferring-flavoprotein dehydrogenase compare
HP15_98 +0.9 1.4 secreted protein with internal repeats-like protein compare
HP15_1933 +0.9 2.4 transcriptional regulator, GntR family compare
HP15_1177 +0.9 1.0 (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase compare
HP15_1006 +0.9 2.1 transcriptional regulator, MerR family compare
HP15_2392 +0.9 2.3 conserved hypothetical protein compare
HP15_200 +0.9 5.9 peptide ABC transporter, periplasmic peptide-binding protein compare
HP15_p187g33 +0.9 3.1 conserved hypothetical protein, membrane compare
HP15_3344 +0.9 5.2 phosphate transporter family protein compare
HP15_1778 +0.9 1.8 poly(hydroxyalkanoate) granule-associated protein compare
HP15_447 +0.9 5.0 glycosyltransferase compare
HP15_2099 +0.9 4.8 DEAD/DEAH box helicase domain protein compare
HP15_p42g32 +0.9 1.3 hypothetical protein compare
HP15_683 +0.9 3.7 conserved hypothetical protein compare
HP15_1800 +0.8 1.2 conserved hypothetical protein, membrane compare
HP15_2731 +0.8 4.1 choline/carnitine/betaine transporter compare
HP15_2164 +0.8 3.9 ATP-binding protein of sugar ABC transporter compare
HP15_1931 +0.8 3.7 2-methylcitrate synthase/citrate synthase II compare
HP15_1997 +0.8 0.9 hypothetical protein compare
HP15_1037 +0.8 2.2 two-component response regulator compare
HP15_202 +0.8 6.0 oligopeptide/dipeptide ABC transporter, permease protein compare
HP15_954 +0.8 1.4 peptidoglycan-associated cytoplasmic membrane protein compare
HP15_1130 +0.8 5.5 transporter, BCCT family protein compare
HP15_2353 +0.8 2.2 LemA family protein compare
HP15_1009 +0.8 4.6 acyl-CoA thiolase compare


Specific Phenotypes

For 59 genes in this experiment

For stress Cisplatin in Marinobacter adhaerens HP15

For stress Cisplatin across organisms