Experiment set6IT028 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-4.5	-7.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS08300		-4.5	-3.2	metal-sulfur cluster assembly factor
MMP_RS00300		-4.1	-1.7	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS06355		-4.0	-6.8	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06350		-3.8	-11.1	HesA/MoeB/ThiF family protein
MMP_RS06680		-3.8	-21.0	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01020		-3.7	-2.2	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS06700		-3.7	-18.5	hypothetical protein
MMP_RS06685		-3.6	-19.4	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS07635		-3.6	-14.3	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS05515		-3.6	-15.7	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS03015		-3.5	-14.6	GTP 3' 8-cyclase MoaA
MMP_RS07005		-3.4	-1.4	4Fe-4S binding protein
MMP_RS06345		-3.4	-17.8	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS08820		-3.3	-7.2	hypothetical protein
MMP_RS02010		-3.1	-13.2	PHP domain-containing protein
MMP_RS01005		-3.0	-2.7	riboflavin synthase
MMP_RS04710		-2.8	-2.6	hypothetical protein
MMP_RS04900		-2.8	-22.6	hypothetical protein
MMP_RS01985		-2.7	-11.7	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS06720		-2.7	-10.3	response regulator transcription factor
MMP_RS06715		-2.7	-19.2	cache domain-containing protein
MMP_RS08745		-2.6	-11.1	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS06730		-2.6	-2.2	phosphopantothenate/pantothenate synthetase
MMP_RS08460		-2.6	-3.8	proteasome-activating nucleotidase
MMP_RS07545		-2.6	-2.1	HTH domain-containing protein
MMP_RS01500		-2.5	-4.0	CBS domain-containing protein
MMP_RS07845		-2.5	-4.9	LL-diaminopimelate aminotransferase
MMP_RS03435		-2.5	-4.1	ketol-acid reductoisomerase
MMP_RS06975		-2.5	-3.9	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS02195		-2.4	-6.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS08720		-2.4	-4.1	4Fe-4S binding protein
MMP_RS04615		-2.4	-7.6	PDGLE domain-containing protein
MMP_RS04780		-2.4	-4.9	ribonuclease P
MMP_RS04585		-2.4	-13.7	AIR synthase related protein
MMP_RS01265		-2.3	-3.1	hypothetical protein
MMP_RS06295		-2.3	-8.5	methanogenesis marker 14 protein
MMP_RS01220		-2.3	-12.0	hypothetical protein
MMP_RS03025		-2.3	-10.6	molybdenum cofactor guanylyltransferase
MMP_RS06400		-2.3	-3.4	4Fe-4S binding protein
MMP_RS07445		-2.3	-7.6	helix-turn-helix domain-containing protein
MMP_RS04605		-2.2	-8.3	cobalt ECF transporter T component CbiQ
MMP_RS00040		-2.2	-6.2	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS00895		-2.2	-6.8	hypothetical protein
MMP_RS00305		-2.2	-2.7	phosphoribosyl-ATP diphosphatase
MMP_RS05920		-2.2	-1.2	50S ribosomal protein L37e
MMP_RS06705		-2.1	-8.4	formate/nitrite transporter family protein
MMP_RS03960		-2.1	-2.1	hypothetical protein
MMP_RS07525		-2.1	-11.9	4Fe-4S binding protein
MMP_RS00115		-2.1	-14.5	radical SAM protein
MMP_RS01545		-2.0	-2.1	CBS domain-containing protein
MMP_RS00695		-2.0	-2.1	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS08645		-2.0	-10.4	UPF0179 family protein
MMP_RS03580		-2.0	-6.1	signal recognition particle-docking protein FtsY
MMP_RS05245		-2.0	-12.1	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS06285		-1.9	-4.8	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS08635		-1.9	-3.2	UbiA family prenyltransferase
MMP_RS03315		-1.9	-2.0	ferrous iron transport protein A
MMP_RS02280		-1.9	-1.8	DUF211 domain-containing protein
MMP_RS02235		-1.9	-9.5	CBS domain-containing protein
MMP_RS01980		-1.9	-13.9	trimeric intracellular cation channel family protein
MMP_RS08790		-1.9	-3.5	translation initiation factor IF-2 subunit alpha
MMP_RS03400		-1.8	-3.1	archease
MMP_RS02800		-1.8	-8.8	nucleotidyltransferase domain-containing protein
MMP_RS07365		-1.8	-12.4	2-phosphoglycerate kinase
MMP_RS04620		-1.8	-11.6	cobalt transporter CbiM
MMP_RS06625		-1.8	-3.6	DNA primase
MMP_RS08650		-1.8	-4.9	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS00110		-1.8	-5.1	hypothetical protein
MMP_RS02900		-1.8	-1.1	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS07600		-1.7	-3.7	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS04890		-1.7	-1.7	adenylyltransferase/cytidyltransferase family protein
MMP_RS00295		-1.7	-4.0	gamma carbonic anhydrase family protein
MMP_RS06630		-1.7	-2.0	UPF0058 family protein
MMP_RS07755		-1.7	-2.3	DUF555 domain-containing protein
MMP_RS01755		-1.7	-2.6	DUF2097 domain-containing protein
MMP_RS08435		-1.7	-2.4	Era-like GTP-binding protein
MMP_RS07605		-1.7	-5.6	diadenylate cyclase
MMP_RS01225		-1.7	-5.6	DUF5379 domain-containing protein
MMP_RS04775		-1.6	-4.4	adenosylhomocysteinase
MMP_RS05550		-1.6	-1.2	cation:proton antiporter
MMP_RS01795		-1.6	-2.2	methanogenesis marker 6 protein
MMP_RS07380		-1.6	-2.8	transcription elongation factor Spt5
MMP_RS06475		-1.6	-5.6	FAD-dependent oxidoreductase
MMP_RS01610		-1.6	-5.9	hypothetical protein
MMP_RS03035		-1.6	-4.4	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS05765		-1.6	-7.6	M42 family metallopeptidase
MMP_RS06105		-1.6	-6.6	hydrogenase maturation peptidase HycI
MMP_RS05430		-1.5	-5.3	TIGR00288 family NYN domain-containing protein
MMP_RS02240		-1.5	-4.0	methanogenesis marker 7 protein
MMP_RS08165		-1.5	-4.3	phosphoglycerate dehydrogenase
MMP_RS06270		-1.5	-6.2	TIGR00300 family protein
MMP_RS07435		-1.5	-2.7	GMP synthase subunit A
MMP_RS07630		-1.5	-2.7	ATP-binding cassette domain-containing protein
MMP_RS01380		-1.5	-4.2	PHP domain-containing protein
MMP_RS06925		-1.5	-3.3	ribonuclease VapC4
MMP_RS03600		-1.5	-2.3	triose-phosphate isomerase
MMP_RS00685		-1.5	-5.1	2-phospho-L-lactate guanylyltransferase
MMP_RS02190		-1.4	-4.7	sulfopyruvate decarboxylase subunit alpha
MMP_RS03640		-1.4	-4.5	archaeal proteasome endopeptidase complex subunit beta
MMP_RS03205		-1.4	-2.8	peptidyl-tRNA hydrolase Pth2
MMP_RS02145		-1.4	-7.5	winged helix-turn-helix transcriptional regulator
MMP_RS06175		-1.4	-9.8	winged helix-turn-helix transcriptional regulator
MMP_RS07575		-1.4	-5.5	RNA ligase partner protein
MMP_RS04870		-1.4	-5.8	TIGR02253 family HAD-type hydrolase
MMP_RS05540		-1.4	-2.8	hypothetical protein
MMP_RS02340		-1.4	-2.5	DNA-directed RNA polymerase subunit E''
MMP_RS01725		-1.3	-5.0	class I SAM-dependent methyltransferase family protein
MMP_RS02165		-1.3	-6.9	tRNA-dihydrouridine synthase
MMP_RS02345		-1.3	-3.4	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00515		-1.3	-1.3	DUF655 domain-containing protein
MMP_RS04685		-1.3	-2.7	DUF126 domain-containing protein
MMP_RS08715		-1.3	-2.0	formylmethanofuran dehydrogenase subunit B
MMP_RS07765		-1.3	-5.8	sodium:alanine symporter family protein
MMP_RS06120		-1.3	-2.7	UPF0147 family protein
MMP_RS01700		-1.2	-1.1	dihydroxy-acid dehydratase
MMP_RS08210		-1.2	-3.3	phosphatidylglycerophosphatase A
MMP_RS01960		-1.2	-1.3	hypothetical protein
MMP_RS02355		-1.2	-1.3	30S ribosomal protein S27ae
MMP_RS06230		-1.2	-3.2	helix-turn-helix domain-containing protein
MMP_RS06200		-1.2	-8.4	M24 family metallopeptidase
MMP_RS00620		-1.2	-8.1	4Fe-4S binding protein
MMP_RS05845		-1.2	-2.5	tRNA-intron lyase
MMP_RS01365		-1.2	-3.9	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS07735		-1.2	-1.5	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS07685		-1.2	-6.6	TIGR01212 family radical SAM protein
MMP_RS01250		-1.1	-4.4	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS03445		-1.1	-1.3	methanogenesis marker 17 protein
MMP_RS08200		-1.1	-8.8	archaeosine synthase subunit alpha
MMP_RS05250		-1.1	-1.6	NFYB/HAP3 family transcription factor subunit
MMP_RS05815		-1.1	-1.8	NOL1/NOP2/sun family putative RNA methylase
MMP_RS02930		-1.1	-2.1	class I SAM-dependent methyltransferase
MMP_RS07710		-1.0	-4.9	cell division protein FtsZ
MMP_RS07730		-1.0	-1.6	pyruvate synthase subunit beta
MMP_RS06940		-1.0	-2.8	polyprenyl diphosphate synthase
MMP_RS01800		-1.0	-3.3	TIGR00303 family protein
MMP_RS06930		-1.0	-6.4	MBL fold metallo-hydrolase
MMP_RS06020		-1.0	-3.4	archaeoflavoprotein AfpA
MMP_RS07390		-1.0	-3.3	cell division protein FtsZ
MMP_RS05510		-1.0	-4.2	Rrf2 family transcriptional regulator
MMP_RS06865		-1.0	-1.4	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS07860		-1.0	-1.2	hypothetical protein
MMP_RS06885		-1.0	-1.8	50S ribosome-binding GTPase
MMP_RS03485		-1.0	-4.0	TIGR00267 family protein
MMP_RS03095		-1.0	-4.2	diphthine synthase
MMP_RS07750		-0.9	-3.3	DUF357 domain-containing protein
MMP_RS07580		-0.9	-2.9	DUF356 domain-containing protein
MMP_RS09020		-0.9	-1.2	hypothetical protein
MMP_RS06895		-0.9	-1.6	selenocysteine-specific translation elongation factor
MMP_RS08320		-0.9	-4.2	molybdopterin molybdotransferase MoeA
MMP_RS01745		-0.9	-3.8	AMP phosphorylase
MMP_RS03250		-0.9	-1.9	MJ1244 family protein
MMP_RS08690		-0.9	-4.9	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS05425		-0.9	-3.4	monovalent cation/H+ antiporter complex subunit F
MMP_RS03590		-0.9	-4.8	METTL5 family protein
MMP_RS07090		-0.9	-4.5	tRNA (adenine-N1)-methyltransferase
MMP_RS05500		-0.9	-5.7	2-isopropylmalate synthase
MMP_RS00810		-0.9	-5.5	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS05345		-0.9	-3.9	hypothetical protein
MMP_RS04955		-0.8	-3.2	DNA topoisomerase I
MMP_RS00985		-0.8	-3.2	CDC48 family AAA ATPase
MMP_RS01925		-0.8	-5.2	DUF1616 domain-containing protein
MMP_RS01385		-0.8	-0.7	imidazole glycerol phosphate synthase subunit HisH
MMP_RS01830		-0.8	-1.8	tRNA-Val
MMP_RS08785		-0.8	-1.1	RNA-protein complex protein Nop10
MMP_RS01075		-0.8	-2.3	hypothetical protein
MMP_RS06340		-0.8	-5.2	phosphoadenosine phosphosulfate reductase family protein
MMP_RS00290		-0.8	-3.2	hypothetical protein
MMP_RS06915		-0.8	-5.2	metallophosphoesterase
MMP_RS01890		-0.8	-2.6	nucleotide sugar dehydrogenase
MMP_RS03475		-0.8	-0.7	hypothetical protein
MMP_RS04720		-0.8	-2.4	DedA family protein
MMP_RS03080		-0.8	-1.2	universal stress protein
MMP_RS05545		-0.8	-3.8	pyridoxal phosphate-dependent aminotransferase
MMP_RS03210		-0.8	-5.9	tRNA guanosine(15) transglycosylase TgtA
MMP_RS01180		-0.8	-1.9	XTP/dITP diphosphatase
MMP_RS01880		-0.8	-4.2	DegT/DnrJ/EryC1/StrS family aminotransferase
MMP_RS05875		-0.7	-2.9	hydroxyethylthiazole kinase
MMP_RS00555		-0.7	-3.2	MFS transporter
MMP_RS03155		-0.7	-3.7	precorrin-6A reductase
MMP_RS00050		-0.7	-4.7	AarF/UbiB family protein
MMP_RS06110		-0.7	-3.0	ATP-dependent protease LonB
MMP_RS02135		-0.7	-2.2	DUF5612 domain-containing protein
MMP_RS07075		-0.7	-2.8	phosphomannomutase/phosphoglucomutase
MMP_RS00520		-0.7	-1.1	RNA polymerase Rpb4 family protein
MMP_RS05800		-0.7	-4.3	B12-binding domain-containing radical SAM protein
MMP_RS06670		-0.7	-3.0	glucose-6-phosphate isomerase
MMP_RS06035		-0.7	-4.5	glycosyltransferase family 2 protein
MMP_RS00915		-0.7	-3.3	DUF116 domain-containing protein
MMP_RS01325		-0.7	-1.9	dihydroneopterin aldolase family protein
MMP_RS01875		-0.7	-4.6	N-acetyltransferase
MMP_RS04695		-0.6	-3.2	selenide water dikinase SelD
MMP_RS02885		-0.6	-5.4	molybdopterin biosynthesis protein
MMP_RS05555		-0.6	-1.1	DUF4040 domain-containing protein
MMP_RS01905		-0.6	-5.1	glycosyltransferase
MMP_RS07425		-0.6	-2.5	GTP-binding protein
MMP_RS08860		-0.6	-4.2	MinD/ParA family protein
MMP_RS03125		-0.6	-3.8	cell division ATPase MinD
MMP_RS01885		-0.6	-3.7	Gfo/Idh/MocA family oxidoreductase
MMP_RS01840		-0.6	-3.8	TIGR00289 family protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments