Experiment set6IT027 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS01370		+2.2	13.9	acetate--CoA ligase family protein
MMP_RS08350		+2.0	2.7	hypothetical protein
MMP_RS06575		+1.5	6.7	fluoride efflux transporter CrcB
MMP_RS08370		+1.4	1.4	cation:proton antiporter subunit C
MMP_RS07115		+1.1	7.3	MBL fold metallo-hydrolase
MMP_RS01775		+1.1	2.4	TIGR00297 family protein
MMP_RS03215		+1.1	8.9	MBL fold metallo-hydrolase
MMP_RS03390		+1.1	5.2	malate dehydrogenase
MMP_RS06570		+1.0	4.1	DUF190 domain-containing protein
MMP_RS03320		+1.0	3.2	metal-dependent transcriptional regulator
MMP_RS07850		+1.0	2.6	prephenate dehydratase
MMP_RS02790		+1.0	1.9	class III signal peptide-containing protein
MMP_RS03420		+1.0	4.7	acetolactate synthase small subunit
MMP_RS08360		+1.0	5.4	hypothetical protein
MMP_RS08365		+0.9	5.6	energy conserving hydrogenase EhbF
MMP_RS07955		+0.9	5.7	FumA C-terminus/TtdB family hydratase beta subunit
MMP_RS07415		+0.8	5.7	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMP_RS05535		+0.8	4.2	hypothetical protein
MMP_RS06770		+0.8	4.5	DHH family phosphoesterase
MMP_RS07125		+0.8	3.0	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05950		+0.8	5.2	nickel-dependent hydrogenase large subunit
MMP_RS06325		+0.8	1.8	hypothetical protein
MMP_RS08355		+0.8	4.1	Na(+)/H(+) antiporter subunit B
MMP_RS08345		+0.8	5.5	4Fe-4S binding protein
MMP_RS01540		+0.7	3.0	DUF504 domain-containing protein
MMP_RS08335		+0.7	3.6	NADH-quinone oxidoreductase subunit B family protein
MMP_RS06600		+0.7	1.4	class III signal peptide-containing protein
MMP_RS07555		+0.7	0.8	monovalent cation/H+ antiporter subunit E
MMP_RS06555		+0.7	3.0	cupin domain-containing protein
MMP_RS08340		+0.7	3.0	4Fe-4S binding protein
MMP_RS00735		+0.7	2.0	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS07725		+0.7	3.3	4Fe-4S dicluster domain-containing protein
MMP_RS00450		+0.7	1.4	4Fe-4S binding protein
MMP_RS08760		+0.7	1.6	hypothetical protein
MMP_RS07120		+0.7	4.9	coenzyme F420 hydrogenase subunit alpha
MMP_RS00520		+0.6	1.5	RNA polymerase Rpb4 family protein
MMP_RS08275		+0.6	4.7	hypothetical protein
MMP_RS03450		+0.6	2.3	glycine synthesis protein GlyXS (from data)
MMP_RS07820		+0.6	2.8	UPF0104 family protein
MMP_RS08440		+0.6	1.9	cell division protein SepF
MMP_RS04265		+0.6	2.7	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS07410		+0.6	3.9	4-demethylwyosine synthase TYW1
MMP_RS07130		+0.6	3.9	coenzyme F420 hydrogenase subunit gamma
MMP_RS06540		+0.6	2.4	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS02960		+0.6	3.4	class I SAM-dependent methyltransferase family protein
MMP_RS06290		+0.6	3.2	DNA repair and recombination protein RadA
MMP_RS00530		+0.6	3.5	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS02490		+0.6	1.9	hypothetical protein
MMP_RS06535		+0.5	3.0	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS02265		+0.5	1.7	nitroreductase family protein
MMP_RS06335		+0.5	2.9	HAD family hydrolase
MMP_RS02310		+0.5	1.3	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS06395		+0.5	2.1	ThiF family adenylyltransferase
MMP_RS00315		+0.5	2.5	Nif3-like dinuclear metal center hexameric protein
MMP_RS00730		+0.5	2.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS03245		+0.5	2.6	DNA repair and recombination protein RadB
MMP_RS07695		+0.5	2.6	DUF3236 domain-containing protein
MMP_RS05525		+0.5	2.2	calcium/sodium antiporter
MMP_RS01115		+0.5	2.9	molybdopterin molybdotransferase MoeA
MMP_RS01475		+0.5	3.5	phosphosulfolactate synthase
MMP_RS07615		+0.5	2.6	energy-coupling factor ABC transporter permease
MMP_RS08215		+0.5	1.5	DUF483 domain-containing protein
MMP_RS06530		+0.5	2.0	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS08310		+0.5	1.4	TMEM165/GDT1 family protein
MMP_RS07815		+0.5	0.9	DUF2120 domain-containing protein
MMP_RS01940		+0.5	2.3	MoxR family ATPase
MMP_RS00725		+0.5	2.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS06435		+0.5	3.1	CBS domain-containing protein
MMP_RS02410		+0.5	1.1	ABC transporter substrate-binding protein
MMP_RS08705		+0.4	2.1	sulfopyruvate decarboxylase subunit beta
MMP_RS04850		+0.4	3.7	UPF0254 family protein
MMP_RS01945		+0.4	2.9	DUF4350 domain-containing protein
MMP_RS05970		+0.4	1.6	class II SORL domain-containing protein
MMP_RS07135		+0.4	2.7	coenzyme F420 hydrogenase subunit beta
MMP_RS07335		+0.4	2.2	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS07700		+0.4	2.8	DUF1188 domain-containing protein
MMP_RS09050		+0.4	2.2	CAP domain-containing protein
MMP_RS07620		+0.4	1.6	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS01525		+0.4	1.1	nucleoside-diphosphate kinase
MMP_RS00565		+0.4	2.4	CBS domain-containing protein
MMP_RS01155		+0.4	2.5	XRE family transcriptional regulator
MMP_RS07095		+0.4	1.5	PspC domain-containing protein
MMP_RS05450		+0.4	2.1	CoB--CoM heterodisulfide reductase subunit C
MMP_RS00665		+0.4	1.4	hypothetical protein
MMP_RS00055		+0.4	3.0	DUF2254 domain-containing protein
MMP_RS02495		+0.4	1.3	hypothetical protein
MMP_RS08400		+0.4	1.9	MJ0307 family thioredoxin
MMP_RS02805		+0.4	0.7	HEPN domain-containing protein
MMP_RS01930		+0.4	3.5	hypothetical protein
MMP_RS00750		+0.4	0.8	fumarate hydratase
MMP_RS01950		+0.4	2.9	hypothetical protein
MMP_RS00940		+0.4	2.3	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS06965		+0.4	2.0	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS05990		+0.4	1.6	DsrE family protein
MMP_RS08075		+0.4	2.3	DUF749 domain-containing protein
MMP_RS00660		+0.4	2.7	alkaline phosphatase family protein
MMP_RS02870		+0.4	2.9	hypothetical protein
MMP_RS03785		+0.4	1.8	cupin domain-containing protein
MMP_RS06550		+0.3	2.0	AMP-binding protein
MMP_RS08995		+0.3	0.6	hypothetical protein
MMP_RS08500		+0.3	1.6	pyridoxal 5'-phosphate synthase glutaminase subunit PdxT
MMP_RS05295		+0.3	2.1	minichromosome maintenance protein MCM
MMP_RS04520		+0.3	1.6	nucleoside deaminase
MMP_RS08430		+0.3	2.2	HAD family hydrolase
MMP_RS06430		+0.3	1.5	6-carboxytetrahydropterin synthase QueD
MMP_RS06185		+0.3	1.7	thermonuclease family protein
MMP_RS00105		+0.3	2.5	hypothetical protein
MMP_RS01100		+0.3	0.8	ABC transporter ATP-binding protein
MMP_RS08315		+0.3	1.0	S-methyl-5-thioribose-1-phosphate isomerase
MMP_RS05975		+0.3	0.7	hypothetical protein
MMP_RS00325		+0.3	0.7	RNA-binding protein
MMP_RS08700		+0.3	1.5	hypothetical protein
MMP_RS01080		+0.3	1.8	DUF2202 domain-containing protein
MMP_RS06860		+0.3	0.7	4Fe-4S binding protein
MMP_RS03115		+0.3	2.6	hypothetical protein
MMP_RS00560		+0.3	2.3	cation:proton antiporter
MMP_RS02895		+0.3	1.8	DHH family phosphoesterase
MMP_RS03910		+0.3	1.0	hypothetical protein
MMP_RS01455		+0.3	2.3	nickel pincer cofactor biosynthesis protein LarC
MMP_RS08470		+0.3	1.8	ATP-binding cassette domain-containing protein
MMP_RS07875		+0.3	1.4	hypothetical protein
MMP_RS00385		+0.3	1.8	P-II family nitrogen regulator
MMP_RS01675		+0.3	0.7	hypothetical protein
MMP_RS05640		+0.3	1.8	UTP--glucose-1-phosphate uridylyltransferase GalU
MMP_RS02815		+0.3	1.2	hypothetical protein
MMP_RS00100		+0.3	2.2	tRNA pseudouridine(13) synthase TruD
MMP_RS00825		+0.3	1.2	fumarylacetoacetate hydrolase family protein
MMP_RS03395		+0.3	1.5	hypothetical protein
MMP_RS08835		+0.3	1.8	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS00630		+0.3	2.2	ECF transporter S component
MMP_RS05945		+0.3	1.7	CBS domain-containing protein
MMP_RS03740		+0.3	1.4	indolepyruvate oxidoreductase subunit beta
MMP_RS08160		+0.3	1.9	EamA family transporter
MMP_RS08775		+0.3	1.7	methanogenesis marker 9 domain-containing protein
MMP_RS01580		+0.3	1.6	PQQ-binding-like beta-propeller repeat protein
MMP_RS00375		+0.3	2.1	ammonium transporter
MMP_RS04480		+0.3	2.4	lysine 2 3-aminomutase
MMP_RS08265		+0.3	0.9	rubrerythrin
MMP_RS05505		+0.3	2.2	class IV adenylate cyclase
MMP_RS06440		+0.3	1.3	CBS domain-containing protein
MMP_RS00185		+0.3	2.2	potassium channel protein
MMP_RS05355		+0.3	0.4	hypothetical protein
MMP_RS00740		+0.3	1.1	cyclase family protein
MMP_RS00800		+0.3	2.0	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS01430		+0.3	1.3	mechanosensitive ion channel family protein
MMP_RS07855		+0.3	1.7	class I SAM-dependent methyltransferase
MMP_RS07925		+0.3	0.7	haloacid dehalogenase
MMP_RS04015		+0.3	1.0	hypothetical protein
MMP_RS06515		+0.3	0.9	UPF0489 family protein
MMP_RS00855		+0.3	1.0	DUF367 family protein
MMP_RS05720		+0.3	1.1	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS05265		+0.3	0.5	2-isopropylmalate synthase
MMP_RS06300		+0.2	1.7	ABC transporter substrate-binding protein
MMP_RS02440		+0.2	1.4	hypothetical protein
MMP_RS00545		+0.2	1.1	XRE family transcriptional regulator
MMP_RS02020		+0.2	0.9	gamma-glutamylcyclotransferase
MMP_RS05175		+0.2	1.4	hypothetical protein
MMP_RS07915		+0.2	1.3	DUF4870 domain-containing protein
MMP_RS08085		+0.2	1.8	hypothetical protein
MMP_RS02360		+0.2	1.5	hypothetical protein
MMP_RS02085		+0.2	1.8	inosine/xanthosine triphosphatase
MMP_RS03965		+0.2	0.7	hypothetical protein
MMP_RS02045		+0.2	0.6	tRNA-Met
MMP_RS06015		+0.2	1.3	flavodoxin family protein
MMP_RS04965		+0.2	1.6	thioredoxin family protein
MMP_RS08380		+0.2	1.0	phosphatase PAP2 family protein
MMP_RS00395		+0.2	0.5	MGMT family protein
MMP_RS00865		+0.2	1.4	SLC13 family permease
MMP_RS01055		+0.2	1.0	hypothetical protein
MMP_RS03405		+0.2	1.4	RNA 3'-terminal phosphate cyclase
MMP_RS08235		+0.2	1.3	hypothetical protein
MMP_RS03790		+0.2	1.4	hypothetical protein
MMP_RS03385		+0.2	0.4	cation diffusion facilitator family transporter
MMP_RS05275		+0.2	1.6	AI-2E family transporter
MMP_RS00930		+0.2	0.8	ABC transporter permease
MMP_RS02325		+0.2	1.7	epoxyqueuosine reductase
MMP_RS00155		+0.2	1.0	heavy metal-binding domain-containing protein
MMP_RS01515		+0.2	1.6	PINc/VapC family ATPase
MMP_RS01435		+0.2	1.5	DMT family transporter
MMP_RS03110		+0.2	0.9	glycosyltransferase family 2 protein
MMP_RS05170		+0.2	1.2	lysine exporter LysO family protein
MMP_RS04175		+0.2	1.6	permease
MMP_RS03460		+0.2	1.3	U32 family peptidase
MMP_RS00635		+0.2	1.2	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS05980		+0.2	1.3	ferritin
MMP_RS05960		+0.2	1.5	CoB--CoM heterodisulfide reductase subunit B
MMP_RS04740		+0.2	1.0	DUF473 domain-containing protein
MMP_RS07680		+0.2	1.0	DUF366 family protein
MMP_RS05020		+0.2	0.8	hypothetical protein
MMP_RS08480		+0.2	1.6	molybdate ABC transporter substrate-binding protein
MMP_RS06490		+0.2	1.1	hypothetical protein
MMP_RS01485		+0.2	1.4	right-handed parallel beta-helix repeat-containing protein
MMP_RS01415		+0.2	0.8	DUF2067 domain-containing protein
MMP_RS06840		+0.2	0.3	DNA-directed RNA polymerase subunit N
MMP_RS01130		+0.2	1.1	flavoprotein
MMP_RS07960		+0.2	1.2	sugar phosphate isomerase/epimerase
MMP_RS08655		+0.2	1.5	phosphoadenosine phosphosulfate reductase family protein
MMP_RS00625		+0.2	1.6	hypothetical protein
MMP_RS00085		+0.2	1.4	DNA cytosine methyltransferase
MMP_RS07970		+0.2	0.8	hypothetical protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments