Experiment set6IT025 for Methanococcus maripaludis S2

Compare to:

formate McAA p-aminobenzoic acid dropout

200 most important genes:

  gene name fitness t score description  
MMP_RS08300 -5.4 -2.8 metal-sulfur cluster assembly factor compare
MMP_RS01175 -4.6 -10.5 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06355 -4.1 -5.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06700 -3.9 -18.4 hypothetical protein compare
MMP_RS06680 -3.7 -21.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06350 -3.7 -12.4 HesA/MoeB/ThiF family protein compare
MMP_RS06685 -3.6 -21.3 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS07635 -3.5 -12.2 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS03015 -3.5 -18.5 GTP 3' 8-cyclase MoaA compare
MMP_RS05515 -3.4 -11.2 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06345 -3.2 -16.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS02280 -3.1 -2.2 DUF211 domain-containing protein compare
MMP_RS01985 -3.0 -8.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS01755 -3.0 -3.0 DUF2097 domain-containing protein compare
MMP_RS08820 -2.9 -12.6 hypothetical protein compare
MMP_RS03315 -2.9 -2.1 ferrous iron transport protein A compare
MMP_RS04900 -2.9 -23.3 hypothetical protein compare
MMP_RS06720 -2.8 -15.8 response regulator transcription factor compare
MMP_RS08745 -2.8 -10.2 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS06715 -2.8 -19.7 cache domain-containing protein compare
MMP_RS02010 -2.8 -15.5 PHP domain-containing protein compare
MMP_RS00040 -2.8 -7.0 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS01545 -2.8 -2.5 CBS domain-containing protein compare
MMP_RS01020 -2.8 -2.4 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS00895 -2.7 -9.3 hypothetical protein compare
MMP_RS02195 -2.7 -8.8 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07005 -2.6 -1.5 4Fe-4S binding protein compare
MMP_RS04585 -2.5 -14.6 AIR synthase related protein compare
MMP_RS03600 -2.5 -3.6 triose-phosphate isomerase compare
MMP_RS08460 -2.5 -5.7 proteasome-activating nucleotidase compare
MMP_RS00300 -2.4 -1.8 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS00515 -2.4 -1.7 DUF655 domain-containing protein compare
MMP_RS06705 -2.4 -8.8 formate/nitrite transporter family protein compare
MMP_RS00115 -2.4 -14.3 radical SAM protein compare
MMP_RS06400 -2.3 -3.6 4Fe-4S binding protein compare
MMP_RS06285 -2.3 -6.0 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS07525 -2.3 -11.9 4Fe-4S binding protein compare
MMP_RS07445 -2.3 -7.5 helix-turn-helix domain-containing protein compare
MMP_RS06295 -2.3 -7.9 methanogenesis marker 14 protein compare
MMP_RS04775 -2.2 -4.4 adenosylhomocysteinase compare
MMP_RS07845 -2.2 -5.4 LL-diaminopimelate aminotransferase compare
MMP_RS03580 -2.2 -5.5 signal recognition particle-docking protein FtsY compare
MMP_RS08720 -2.2 -3.7 4Fe-4S binding protein compare
MMP_RS00695 -2.2 -2.1 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS04605 -2.1 -8.0 cobalt ECF transporter T component CbiQ compare
MMP_RS01500 -2.1 -4.9 CBS domain-containing protein compare
MMP_RS01265 -2.1 -3.1 hypothetical protein compare
MMP_RS06975 -2.1 -5.7 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS01220 -2.1 -11.8 hypothetical protein compare
MMP_RS08645 -2.1 -10.8 UPF0179 family protein compare
MMP_RS02235 -2.0 -11.7 CBS domain-containing protein compare
MMP_RS07735 -2.0 -1.7 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS08790 -2.0 -4.6 translation initiation factor IF-2 subunit alpha compare
MMP_RS06105 -2.0 -9.3 hydrogenase maturation peptidase HycI compare
MMP_RS02800 -1.9 -8.0 nucleotidyltransferase domain-containing protein compare
MMP_RS02240 -1.9 -5.5 methanogenesis marker 7 protein compare
MMP_RS01005 -1.9 -2.6 riboflavin synthase compare
MMP_RS01980 -1.9 -12.6 trimeric intracellular cation channel family protein compare
MMP_RS04780 -1.9 -3.6 ribonuclease P compare
MMP_RS07605 -1.9 -4.0 diadenylate cyclase compare
MMP_RS04615 -1.9 -4.7 PDGLE domain-containing protein compare
MMP_RS06730 -1.8 -3.0 phosphopantothenate/pantothenate synthetase compare
MMP_RS08715 -1.8 -2.9 formylmethanofuran dehydrogenase subunit B compare
MMP_RS00620 -1.8 -9.3 4Fe-4S binding protein compare
MMP_RS06230 -1.8 -3.6 helix-turn-helix domain-containing protein compare
MMP_RS05245 -1.8 -12.5 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS08435 -1.8 -3.2 Era-like GTP-binding protein compare
MMP_RS07730 -1.8 -3.5 pyruvate synthase subunit beta compare
MMP_RS06625 -1.7 -2.8 DNA primase compare
MMP_RS03025 -1.7 -6.1 molybdenum cofactor guanylyltransferase compare
MMP_RS02900 -1.7 -1.1 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS07575 -1.7 -5.1 RNA ligase partner protein compare
MMP_RS01385 -1.6 -1.2 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS00685 -1.6 -5.7 2-phospho-L-lactate guanylyltransferase compare
MMP_RS06475 -1.6 -6.7 FAD-dependent oxidoreductase compare
MMP_RS07365 -1.6 -11.6 2-phosphoglycerate kinase compare
MMP_RS03475 -1.6 -1.2 hypothetical protein compare
MMP_RS04620 -1.6 -9.0 cobalt transporter CbiM compare
MMP_RS04870 -1.6 -5.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS00305 -1.5 -2.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS05920 -1.5 -1.1 50S ribosomal protein L37e compare
MMP_RS01225 -1.5 -3.7 DUF5379 domain-containing protein compare
MMP_RS07600 -1.5 -4.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS06925 -1.5 -3.1 ribonuclease VapC4 compare
MMP_RS05540 -1.5 -3.9 hypothetical protein compare
MMP_RS05765 -1.5 -7.8 M42 family metallopeptidase compare
MMP_RS03035 -1.5 -4.3 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS02190 -1.5 -3.8 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS01380 -1.5 -5.3 PHP domain-containing protein compare
MMP_RS08165 -1.5 -2.5 phosphoglycerate dehydrogenase compare
MMP_RS06270 -1.5 -5.7 TIGR00300 family protein compare
MMP_RS07765 -1.5 -7.2 sodium:alanine symporter family protein compare
MMP_RS02145 -1.4 -6.7 winged helix-turn-helix transcriptional regulator compare
MMP_RS02355 -1.4 -4.1 30S ribosomal protein S27ae compare
MMP_RS01800 -1.4 -4.7 TIGR00303 family protein compare
MMP_RS06885 -1.4 -4.0 50S ribosome-binding GTPase compare
MMP_RS04890 -1.4 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS08635 -1.4 -3.0 UbiA family prenyltransferase compare
MMP_RS00295 -1.4 -3.6 gamma carbonic anhydrase family protein compare
MMP_RS02165 -1.4 -7.5 tRNA-dihydrouridine synthase compare
MMP_RS03445 -1.4 -1.7 methanogenesis marker 17 protein compare
MMP_RS00110 -1.3 -2.7 hypothetical protein compare
MMP_RS01725 -1.3 -4.9 class I SAM-dependent methyltransferase family protein compare
MMP_RS05430 -1.3 -5.6 TIGR00288 family NYN domain-containing protein compare
MMP_RS07630 -1.3 -1.8 ATP-binding cassette domain-containing protein compare
MMP_RS04710 -1.3 -2.1 hypothetical protein compare
MMP_RS03435 -1.3 -2.0 ketol-acid reductoisomerase compare
MMP_RS03485 -1.3 -3.7 TIGR00267 family protein compare
MMP_RS08210 -1.3 -3.0 phosphatidylglycerophosphatase A compare
MMP_RS03960 -1.3 -1.7 hypothetical protein compare
MMP_RS01960 -1.3 -1.1 hypothetical protein compare
MMP_RS08200 -1.3 -10.4 archaeosine synthase subunit alpha compare
MMP_RS06020 -1.3 -5.1 archaeoflavoprotein AfpA compare
MMP_RS06200 -1.2 -8.5 M24 family metallopeptidase compare
MMP_RS00060 -1.2 -2.3 3-dehydroquinate synthase II compare
MMP_RS07390 -1.2 -3.1 cell division protein FtsZ compare
MMP_RS04685 -1.2 -2.7 DUF126 domain-containing protein compare
MMP_RS06940 -1.2 -2.8 polyprenyl diphosphate synthase compare
MMP_RS06175 -1.2 -8.3 winged helix-turn-helix transcriptional regulator compare
MMP_RS06120 -1.2 -2.8 UPF0147 family protein compare
MMP_RS07710 -1.2 -5.6 cell division protein FtsZ compare
MMP_RS01795 -1.2 -2.4 methanogenesis marker 6 protein compare
MMP_RS02340 -1.2 -2.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS08940 -1.1 -2.1 MetS family NSS transporter small subunit compare
MMP_RS07200 -1.1 -5.7 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02345 -1.1 -2.5 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS01365 -1.1 -4.2 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS01325 -1.1 -2.7 dihydroneopterin aldolase family protein compare
MMP_RS07545 -1.1 -1.6 HTH domain-containing protein compare
MMP_RS03640 -1.1 -4.2 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS05845 -1.1 -2.4 tRNA-intron lyase compare
MMP_RS05510 -1.0 -4.4 Rrf2 family transcriptional regulator compare
MMP_RS03400 -1.0 -2.7 archease compare
MMP_RS06865 -1.0 -1.5 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS06630 -1.0 -1.3 UPF0058 family protein compare
MMP_RS00675 -1.0 -1.5 nitroreductase family protein compare
MMP_RS09020 -1.0 -2.0 hypothetical protein compare
MMP_RS01250 -1.0 -3.8 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS07580 -1.0 -2.4 DUF356 domain-containing protein compare
MMP_RS07685 -1.0 -4.7 TIGR01212 family radical SAM protein compare
MMP_RS05555 -1.0 -1.9 DUF4040 domain-containing protein compare
MMP_RS08320 -1.0 -3.8 molybdopterin molybdotransferase MoeA compare
MMP_RS07750 -0.9 -3.7 DUF357 domain-containing protein compare
MMP_RS01745 -0.9 -4.6 AMP phosphorylase compare
MMP_RS06930 -0.9 -5.1 MBL fold metallo-hydrolase compare
MMP_RS05550 -0.9 -0.9 cation:proton antiporter compare
MMP_RS05875 -0.9 -5.2 hydroxyethylthiazole kinase compare
MMP_RS03205 -0.9 -2.1 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07385 -0.9 -1.3 protein translocase SEC61 complex subunit gamma compare
MMP_RS00810 -0.9 -5.1 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS07380 -0.9 -1.9 transcription elongation factor Spt5 compare
MMP_RS01830 -0.9 -1.6 tRNA-Val compare
MMP_RS01610 -0.9 -2.8 hypothetical protein compare
MMP_RS00050 -0.9 -5.7 AarF/UbiB family protein compare
MMP_RS05500 -0.9 -5.0 2-isopropylmalate synthase compare
MMP_RS00555 -0.9 -3.6 MFS transporter compare
MMP_RS06895 -0.8 -1.8 selenocysteine-specific translation elongation factor compare
MMP_RS07755 -0.8 -1.7 DUF555 domain-containing protein compare
MMP_RS03590 -0.8 -4.0 METTL5 family protein compare
MMP_RS01575 -0.8 -5.2 aldolase compare
MMP_RS01840 -0.8 -5.2 TIGR00289 family protein compare
MMP_RS06215 -0.8 -3.2 30S ribosomal protein S6e compare
MMP_RS03155 -0.8 -4.6 precorrin-6A reductase compare
MMP_RS08690 -0.8 -4.2 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS08650 -0.8 -2.9 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS05545 -0.8 -4.0 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS01890 -0.7 -3.3 nucleotide sugar dehydrogenase compare
MMP_RS07075 -0.7 -2.6 phosphomannomutase/phosphoglucomutase compare
MMP_RS03250 -0.7 -2.4 MJ1244 family protein compare
MMP_RS03095 -0.7 -4.6 diphthine synthase compare
MMP_RS00985 -0.7 -3.9 CDC48 family AAA ATPase compare
MMP_RS03210 -0.7 -5.5 tRNA guanosine(15) transglycosylase TgtA compare
MMP_RS00915 -0.7 -3.6 DUF116 domain-containing protein compare
MMP_RS08445 -0.7 -2.8 DUF2099 family protein compare
MMP_RS03470 -0.7 -4.2 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS06670 -0.7 -2.6 glucose-6-phosphate isomerase compare
MMP_RS06675 -0.7 -3.8 ADP-specific phosphofructokinase compare
MMP_RS07090 -0.7 -3.8 tRNA (adenine-N1)-methyltransferase compare
MMP_RS01240 -0.7 -0.7 7-cyano-7-deazaguanine synthase QueC compare
MMP_RS01720 -0.7 -0.9 replication factor C large subunit compare
MMP_RS04955 -0.7 -3.1 DNA topoisomerase I compare
MMP_RS06915 -0.7 -4.0 metallophosphoesterase compare
MMP_RS06855 -0.7 -4.3 hypothetical protein compare
MMP_RS01905 -0.7 -5.4 glycosyltransferase compare
MMP_RS06920 -0.7 -5.2 AAA family ATPase compare
MMP_RS05285 -0.6 -3.2 MMPL family transporter compare
MMP_RS06340 -0.6 -4.6 phosphoadenosine phosphosulfate reductase family protein compare
MMP_RS00520 -0.6 -0.9 RNA polymerase Rpb4 family protein compare
MMP_RS03700 -0.6 -3.9 sodium:proton antiporter compare
MMP_RS02170 -0.6 -4.1 CBS domain-containing protein compare
MMP_RS01875 -0.6 -4.5 N-acetyltransferase compare
MMP_RS08915 -0.6 -1.0 2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase compare
MMP_RS01700 -0.6 -0.9 dihydroxy-acid dehydratase compare
MMP_RS01045 -0.6 -4.3 diphthamide biosynthesis enzyme Dph2 compare
MMP_RS01925 -0.6 -4.3 DUF1616 domain-containing protein compare
MMP_RS01440 -0.6 -4.3 NAAT family transporter compare
MMP_RS02930 -0.6 -1.2 class I SAM-dependent methyltransferase compare
MMP_RS07705 -0.6 -3.7 transcriptional regulator compare
MMP_RS04695 -0.6 -3.6 selenide water dikinase SelD compare
MMP_RS02135 -0.6 -2.6 DUF5612 domain-containing protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments