Experiment set6IT024 for Methanococcus maripaludis S2

Compare to:

formate McAA B12 dropout

200 most important genes:

  gene name fitness t score description  
MMP_RS01005 -4.6 -1.9 riboflavin synthase compare
MMP_RS06700 -4.1 -15.4 hypothetical protein compare
MMP_RS06680 -3.9 -19.5 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS03015 -3.9 -16.6 GTP 3' 8-cyclase MoaA compare
MMP_RS06350 -3.8 -6.7 HesA/MoeB/ThiF family protein compare
MMP_RS06685 -3.7 -20.1 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS01545 -3.7 -2.1 CBS domain-containing protein compare
MMP_RS01175 -3.6 -5.3 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS05515 -3.6 -12.3 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06345 -3.4 -16.9 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS06355 -3.3 -5.4 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS01985 -3.3 -10.8 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08720 -3.3 -3.2 4Fe-4S binding protein compare
MMP_RS01385 -3.3 -1.3 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS06715 -3.3 -20.8 cache domain-containing protein compare
MMP_RS01020 -3.2 -2.0 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS06720 -3.1 -13.8 response regulator transcription factor compare
MMP_RS04900 -3.0 -22.1 hypothetical protein compare
MMP_RS07635 -3.0 -10.6 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS02010 -3.0 -11.9 PHP domain-containing protein compare
MMP_RS08300 -2.9 -2.6 metal-sulfur cluster assembly factor compare
MMP_RS07525 -2.9 -11.7 4Fe-4S binding protein compare
MMP_RS08820 -2.9 -5.7 hypothetical protein compare
MMP_RS06400 -2.8 -3.6 4Fe-4S binding protein compare
MMP_RS06705 -2.8 -10.1 formate/nitrite transporter family protein compare
MMP_RS02280 -2.7 -1.9 DUF211 domain-containing protein compare
MMP_RS07445 -2.6 -8.5 helix-turn-helix domain-containing protein compare
MMP_RS08745 -2.5 -9.6 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS00300 -2.5 -1.6 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS06295 -2.5 -9.5 methanogenesis marker 14 protein compare
MMP_RS04780 -2.5 -4.2 ribonuclease P compare
MMP_RS04710 -2.4 -3.1 hypothetical protein compare
MMP_RS01220 -2.4 -11.6 hypothetical protein compare
MMP_RS08460 -2.4 -4.2 proteasome-activating nucleotidase compare
MMP_RS04585 -2.3 -11.3 AIR synthase related protein compare
MMP_RS01980 -2.3 -15.4 trimeric intracellular cation channel family protein compare
MMP_RS00305 -2.3 -3.3 phosphoribosyl-ATP diphosphatase compare
MMP_RS00040 -2.2 -5.0 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS08715 -2.2 -2.7 formylmethanofuran dehydrogenase subunit B compare
MMP_RS01500 -2.2 -3.4 CBS domain-containing protein compare
MMP_RS06625 -2.2 -3.9 DNA primase compare
MMP_RS03025 -2.2 -6.0 molybdenum cofactor guanylyltransferase compare
MMP_RS00895 -2.2 -6.1 hypothetical protein compare
MMP_RS01265 -2.1 -2.8 hypothetical protein compare
MMP_RS08645 -2.1 -9.7 UPF0179 family protein compare
MMP_RS03600 -2.1 -2.4 triose-phosphate isomerase compare
MMP_RS06630 -2.1 -2.0 UPF0058 family protein compare
MMP_RS02195 -2.1 -6.1 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS07545 -2.1 -2.4 HTH domain-containing protein compare
MMP_RS04605 -2.0 -6.3 cobalt ECF transporter T component CbiQ compare
MMP_RS02240 -2.0 -4.8 methanogenesis marker 7 protein compare
MMP_RS01700 -2.0 -1.7 dihydroxy-acid dehydratase compare
MMP_RS05920 -2.0 -1.1 50S ribosomal protein L37e compare
MMP_RS07630 -2.0 -2.8 ATP-binding cassette domain-containing protein compare
MMP_RS06975 -2.0 -4.6 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS06105 -2.0 -9.6 hydrogenase maturation peptidase HycI compare
MMP_RS04775 -2.0 -5.9 adenosylhomocysteinase compare
MMP_RS07845 -1.9 -4.0 LL-diaminopimelate aminotransferase compare
MMP_RS07005 -1.9 -1.2 4Fe-4S binding protein compare
MMP_RS07605 -1.9 -4.7 diadenylate cyclase compare
MMP_RS00115 -1.9 -11.6 radical SAM protein compare
MMP_RS04615 -1.9 -6.9 PDGLE domain-containing protein compare
MMP_RS01380 -1.9 -6.7 PHP domain-containing protein compare
MMP_RS00620 -1.8 -6.7 4Fe-4S binding protein compare
MMP_RS03445 -1.8 -1.7 methanogenesis marker 17 protein compare
MMP_RS06175 -1.8 -11.1 winged helix-turn-helix transcriptional regulator compare
MMP_RS02800 -1.8 -5.9 nucleotidyltransferase domain-containing protein compare
MMP_RS08210 -1.8 -3.2 phosphatidylglycerophosphatase A compare
MMP_RS02165 -1.8 -7.9 tRNA-dihydrouridine synthase compare
MMP_RS07365 -1.8 -11.1 2-phosphoglycerate kinase compare
MMP_RS01610 -1.7 -4.8 hypothetical protein compare
MMP_RS08165 -1.7 -4.2 phosphoglycerate dehydrogenase compare
MMP_RS08790 -1.7 -2.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS05765 -1.7 -8.2 M42 family metallopeptidase compare
MMP_RS06895 -1.7 -2.7 selenocysteine-specific translation elongation factor compare
MMP_RS01755 -1.7 -2.4 DUF2097 domain-containing protein compare
MMP_RS06230 -1.7 -3.0 helix-turn-helix domain-containing protein compare
MMP_RS04620 -1.7 -9.4 cobalt transporter CbiM compare
MMP_RS02235 -1.7 -6.6 CBS domain-containing protein compare
MMP_RS06270 -1.6 -6.5 TIGR00300 family protein compare
MMP_RS07380 -1.6 -2.7 transcription elongation factor Spt5 compare
MMP_RS05555 -1.6 -1.9 DUF4040 domain-containing protein compare
MMP_RS07765 -1.6 -8.0 sodium:alanine symporter family protein compare
MMP_RS07730 -1.6 -2.5 pyruvate synthase subunit beta compare
MMP_RS05540 -1.6 -4.1 hypothetical protein compare
MMP_RS06885 -1.5 -3.5 50S ribosome-binding GTPase compare
MMP_RS06285 -1.5 -3.2 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS06475 -1.5 -5.0 FAD-dependent oxidoreductase compare
MMP_RS03640 -1.5 -3.9 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS07390 -1.5 -2.6 cell division protein FtsZ compare
MMP_RS07735 -1.5 -1.6 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS04890 -1.4 -1.3 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS03580 -1.4 -3.3 signal recognition particle-docking protein FtsY compare
MMP_RS05510 -1.4 -4.0 Rrf2 family transcriptional regulator compare
MMP_RS02355 -1.4 -2.3 30S ribosomal protein S27ae compare
MMP_RS06925 -1.4 -3.6 ribonuclease VapC4 compare
MMP_RS02340 -1.4 -2.6 DNA-directed RNA polymerase subunit E'' compare
MMP_RS05875 -1.4 -4.9 hydroxyethylthiazole kinase compare
MMP_RS06315 -1.4 -1.5 cobalt-precorrin-7 (C(5))-methyltransferase compare
MMP_RS08435 -1.4 -2.0 Era-like GTP-binding protein compare
MMP_RS03960 -1.4 -1.6 hypothetical protein compare
MMP_RS06200 -1.4 -8.0 M24 family metallopeptidase compare
MMP_RS08635 -1.4 -2.3 UbiA family prenyltransferase compare
MMP_RS06215 -1.3 -2.7 30S ribosomal protein S6e compare
MMP_RS01225 -1.3 -4.7 DUF5379 domain-containing protein compare
MMP_RS05430 -1.3 -3.7 TIGR00288 family NYN domain-containing protein compare
MMP_RS07600 -1.3 -3.3 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS07775 -1.3 -5.1 alanine dehydrogenase compare
MMP_RS01665 -1.3 -2.9 DUF2111 domain-containing protein compare
MMP_RS03315 -1.3 -0.9 ferrous iron transport protein A compare
MMP_RS01325 -1.3 -2.9 dihydroneopterin aldolase family protein compare
MMP_RS03400 -1.3 -4.1 archease compare
MMP_RS04870 -1.3 -5.9 TIGR02253 family HAD-type hydrolase compare
MMP_RS01365 -1.3 -3.9 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS02900 -1.3 -0.8 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS01795 -1.2 -2.1 methanogenesis marker 6 protein compare
MMP_RS00695 -1.2 -1.5 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS00130 -1.2 -1.7 nickel-responsive transcriptional regulator NikR compare
MMP_RS00555 -1.2 -4.5 MFS transporter compare
MMP_RS00915 -1.2 -5.7 DUF116 domain-containing protein compare
MMP_RS06020 -1.2 -4.8 archaeoflavoprotein AfpA compare
MMP_RS03250 -1.2 -3.3 MJ1244 family protein compare
MMP_RS05245 -1.1 -6.8 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS06930 -1.1 -6.5 MBL fold metallo-hydrolase compare
MMP_RS00295 -1.1 -3.1 gamma carbonic anhydrase family protein compare
MMP_RS03435 -1.1 -1.8 ketol-acid reductoisomerase compare
MMP_RS04685 -1.1 -2.5 DUF126 domain-containing protein compare
MMP_RS00685 -1.1 -3.1 2-phospho-L-lactate guanylyltransferase compare
MMP_RS01250 -1.1 -4.0 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS03035 -1.1 -2.8 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS03485 -1.1 -2.3 TIGR00267 family protein compare
MMP_RS01960 -1.0 -1.1 hypothetical protein compare
MMP_RS00060 -1.0 -1.9 3-dehydroquinate synthase II compare
MMP_RS07710 -1.0 -4.6 cell division protein FtsZ compare
MMP_RS00290 -1.0 -4.2 hypothetical protein compare
MMP_RS05500 -1.0 -5.4 2-isopropylmalate synthase compare
MMP_RS08940 -1.0 -1.6 MetS family NSS transporter small subunit compare
MMP_RS02190 -1.0 -3.2 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS08690 -1.0 -4.8 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS03305 -1.0 -4.3 winged helix-turn-helix domain-containing protein compare
MMP_RS05800 -1.0 -6.2 B12-binding domain-containing radical SAM protein compare
MMP_RS07625 -1.0 -2.3 cobalt ECF transporter T component CbiQ compare
MMP_RS01745 -1.0 -3.2 AMP phosphorylase compare
MMP_RS05250 -1.0 -1.5 NFYB/HAP3 family transcription factor subunit compare
MMP_RS07425 -1.0 -4.7 GTP-binding protein compare
MMP_RS08200 -0.9 -7.5 archaeosine synthase subunit alpha compare
MMP_RS07685 -0.9 -4.6 TIGR01212 family radical SAM protein compare
MMP_RS00110 -0.9 -2.6 hypothetical protein compare
MMP_RS01575 -0.9 -4.4 aldolase compare
MMP_RS08320 -0.9 -5.0 molybdopterin molybdotransferase MoeA compare
MMP_RS04695 -0.9 -4.3 selenide water dikinase SelD compare
MMP_RS08785 -0.9 -1.2 RNA-protein complex protein Nop10 compare
MMP_RS01440 -0.9 -3.4 NAAT family transporter compare
MMP_RS07575 -0.9 -2.2 RNA ligase partner protein compare
MMP_RS02145 -0.9 -4.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07420 -0.9 -3.1 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS02135 -0.9 -3.8 DUF5612 domain-containing protein compare
MMP_RS03590 -0.9 -3.8 METTL5 family protein compare
MMP_RS08650 -0.9 -2.4 glutamine--fructose-6-phosphate transaminase (isomerizing) compare
MMP_RS07535 -0.9 -5.9 4Fe-4S binding protein compare
MMP_RS05550 -0.9 -0.8 cation:proton antiporter compare
MMP_RS05545 -0.9 -2.9 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS09055 -0.9 -1.2 CAP domain-containing protein compare
MMP_RS06675 -0.8 -4.4 ADP-specific phosphofructokinase compare
MMP_RS01800 -0.8 -2.2 TIGR00303 family protein compare
MMP_RS00475 -0.8 -5.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS00310 -0.8 -5.2 CBS domain-containing protein compare
MMP_RS06870 -0.8 -4.0 DedA family protein compare
MMP_RS05285 -0.8 -3.7 MMPL family transporter compare
MMP_RS06980 -0.8 -3.1 tRNA 2-thiocytidine biosynthesis TtcA family protein compare
MMP_RS07790 -0.8 -3.7 segregation/condensation protein A compare
MMP_RS02345 -0.8 -2.2 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS04145 -0.8 -1.7 hypothetical protein compare
MMP_RS01720 -0.8 -1.0 replication factor C large subunit compare
MMP_RS00515 -0.7 -0.7 DUF655 domain-containing protein compare
MMP_RS05635 -0.7 -4.8 NAD-dependent epimerase/dehydratase family protein compare
MMP_RS06940 -0.7 -1.6 polyprenyl diphosphate synthase compare
MMP_RS07755 -0.7 -0.9 DUF555 domain-containing protein compare
MMP_RS01830 -0.7 -1.6 tRNA-Val compare
MMP_RS06590 -0.7 -2.1 GNAT family N-acetyltransferase compare
MMP_RS08095 -0.7 -3.6 dethiobiotin synthase compare
MMP_RS06865 -0.7 -1.0 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS04500 -0.7 -5.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS00050 -0.7 -4.7 AarF/UbiB family protein compare
MMP_RS03205 -0.7 -1.2 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07075 -0.7 -2.3 phosphomannomutase/phosphoglucomutase compare
MMP_RS08595 -0.7 -1.0 flagellar protein C compare
MMP_RS06035 -0.6 -4.4 glycosyltransferase family 2 protein compare
MMP_RS03300 -0.6 -0.8 TOBE domain-containing protein compare
MMP_RS04305 -0.6 -2.1 hypothetical protein compare
MMP_RS08600 -0.6 -1.7 flagellar protein D compare
MMP_RS06915 -0.6 -3.0 metallophosphoesterase compare
MMP_RS06170 -0.6 -3.6 ABC transporter ATP-binding protein compare
MMP_RS05345 -0.6 -3.0 hypothetical protein compare
MMP_RS02405 -0.6 -2.2 hypothetical protein compare
MMP_RS06855 -0.6 -3.9 hypothetical protein compare
MMP_RS05485 -0.6 -4.2 cysteine--tRNA ligase compare
MMP_RS06370 -0.6 -2.9 biotin synthase BioB compare
MMP_RS05815 -0.6 -1.0 NOL1/NOP2/sun family putative RNA methylase compare
MMP_RS07530 -0.6 -4.5 4Fe-4S binding protein compare


Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments