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Experiment set6IT022 for
Methanococcus maripaludis S2
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formate McAA B12 dropout
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS06400
-5.5
-3.3
4Fe-4S binding protein
compare
MMP
_RS06350
-4.9
-10.9
HesA/MoeB/ThiF family protein
compare
MMP
_RS01175
-4.8
-7.2
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS06355
-4.7
-4.3
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS06700
-4.6
-15.8
hypothetical protein
compare
MMP
_RS03015
-4.5
-14.3
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06680
-4.4
-20.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS06685
-4.4
-19.2
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS05515
-4.3
-9.4
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06345
-3.8
-17.4
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS08720
-3.8
-3.6
4Fe-4S binding protein
compare
MMP
_RS07635
-3.8
-9.4
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS00305
-3.7
-4.0
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS01755
-3.6
-2.2
DUF2097 domain-containing protein
compare
MMP
_RS02240
-3.6
-4.9
methanogenesis marker 7 protein
compare
MMP
_RS07445
-3.4
-7.6
helix-turn-helix domain-containing protein
compare
MMP
_RS06715
-3.4
-20.7
cache domain-containing protein
compare
MMP
_RS08300
-3.4
-2.8
metal-sulfur cluster assembly factor
compare
MMP
_RS01545
-3.2
-2.2
CBS domain-containing protein
compare
MMP
_RS07525
-3.2
-14.8
4Fe-4S binding protein
compare
MMP
_RS01500
-3.2
-5.7
CBS domain-containing protein
compare
MMP
_RS02010
-3.2
-15.4
PHP domain-containing protein
compare
MMP
_RS04900
-3.2
-23.7
hypothetical protein
compare
MMP
_RS06720
-3.2
-11.3
response regulator transcription factor
compare
MMP
_RS01985
-3.1
-9.5
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS08820
-3.1
-9.5
hypothetical protein
compare
MMP
_RS02900
-3.0
-1.2
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS00040
-3.0
-5.4
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS04605
-3.0
-7.5
cobalt ECF transporter T component CbiQ
compare
MMP
_RS00695
-3.0
-1.8
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS01020
-2.9
-2.1
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS02355
-2.9
-4.1
30S ribosomal protein S27ae
compare
MMP
_RS03580
-2.8
-5.9
signal recognition particle-docking protein FtsY
compare
MMP
_RS06885
-2.8
-5.5
50S ribosome-binding GTPase
compare
MMP
_RS06705
-2.8
-10.2
formate/nitrite transporter family protein
compare
MMP
_RS06105
-2.8
-11.1
hydrogenase maturation peptidase HycI
compare
MMP
_RS08745
-2.8
-8.0
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS03035
-2.8
-6.2
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS07845
-2.7
-4.0
LL-diaminopimelate aminotransferase
compare
MMP
_RS04615
-2.7
-5.4
PDGLE domain-containing protein
compare
MMP
_RS08460
-2.7
-3.6
proteasome-activating nucleotidase
compare
MMP
_RS06925
-2.7
-3.5
ribonuclease VapC4
compare
MMP
_RS01795
-2.7
-3.6
methanogenesis marker 6 protein
compare
MMP
_RS04585
-2.6
-11.9
AIR synthase related protein
compare
MMP
_RS08635
-2.6
-3.6
UbiA family prenyltransferase
compare
MMP
_RS07605
-2.6
-4.5
diadenylate cyclase
compare
MMP
_RS05920
-2.5
-1.2
50S ribosomal protein L37e
compare
MMP
_RS07365
-2.5
-14.2
2-phosphoglycerate kinase
compare
MMP
_RS03435
-2.5
-2.8
ketol-acid reductoisomerase
compare
MMP
_RS02195
-2.5
-5.0
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS05765
-2.4
-8.4
M42 family metallopeptidase
compare
MMP
_RS08210
-2.4
-3.8
phosphatidylglycerophosphatase A
compare
MMP
_RS01980
-2.4
-16.7
trimeric intracellular cation channel family protein
compare
MMP
_RS01005
-2.4
-2.5
riboflavin synthase
compare
MMP
_RS00115
-2.4
-13.1
radical SAM protein
compare
MMP
_RS01610
-2.4
-4.9
hypothetical protein
compare
MMP
_RS06270
-2.4
-8.6
TIGR00300 family protein
compare
MMP
_RS00295
-2.3
-4.8
gamma carbonic anhydrase family protein
compare
MMP
_RS06285
-2.3
-4.4
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS00620
-2.3
-8.6
4Fe-4S binding protein
compare
MMP
_RS04620
-2.3
-11.5
cobalt transporter CbiM
compare
MMP
_RS02800
-2.3
-7.0
nucleotidyltransferase domain-containing protein
compare
MMP
_RS02165
-2.3
-13.3
tRNA-dihydrouridine synthase
compare
MMP
_RS07545
-2.3
-2.3
HTH domain-containing protein
compare
MMP
_RS07005
-2.3
-1.2
4Fe-4S binding protein
compare
MMP
_RS03640
-2.2
-5.5
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS08715
-2.2
-3.0
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS02340
-2.2
-4.1
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS03445
-2.2
-1.8
methanogenesis marker 17 protein
compare
MMP
_RS01220
-2.2
-11.7
hypothetical protein
compare
MMP
_RS04775
-2.2
-4.9
adenosylhomocysteinase
compare
MMP
_RS08645
-2.2
-8.7
UPF0179 family protein
compare
MMP
_RS04710
-2.1
-3.4
hypothetical protein
compare
MMP
_RS08435
-2.1
-3.5
Era-like GTP-binding protein
compare
MMP
_RS03250
-2.1
-5.1
MJ1244 family protein
compare
MMP
_RS03025
-2.1
-6.8
molybdenum cofactor guanylyltransferase
compare
MMP
_RS07730
-2.1
-3.6
pyruvate synthase subunit beta
compare
MMP
_RS08165
-2.1
-3.3
phosphoglycerate dehydrogenase
compare
MMP
_RS01665
-2.0
-3.4
DUF2111 domain-containing protein
compare
MMP
_RS06175
-2.0
-8.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS06295
-2.0
-7.2
methanogenesis marker 14 protein
compare
MMP
_RS09020
-2.0
-2.9
hypothetical protein
compare
MMP
_RS06625
-1.9
-3.2
DNA primase
compare
MMP
_RS00895
-1.9
-7.2
hypothetical protein
compare
MMP
_RS05875
-1.9
-9.6
hydroxyethylthiazole kinase
compare
MMP
_RS04780
-1.9
-3.8
ribonuclease P
compare
MMP
_RS07600
-1.9
-4.0
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS01265
-1.9
-3.0
hypothetical protein
compare
MMP
_RS03400
-1.9
-4.4
archease
compare
MMP
_RS03600
-1.9
-3.3
triose-phosphate isomerase
compare
MMP
_RS03315
-1.9
-1.7
ferrous iron transport protein A
compare
MMP
_RS00685
-1.9
-5.5
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS00130
-1.9
-2.3
nickel-responsive transcriptional regulator NikR
compare
MMP
_RS01365
-1.9
-5.3
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS02235
-1.8
-6.5
CBS domain-containing protein
compare
MMP
_RS07630
-1.8
-2.7
ATP-binding cassette domain-containing protein
compare
MMP
_RS06975
-1.8
-3.4
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS05430
-1.8
-5.2
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS02280
-1.8
-1.6
DUF211 domain-containing protein
compare
MMP
_RS00300
-1.8
-1.4
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS05540
-1.8
-2.8
hypothetical protein
compare
MMP
_RS07735
-1.8
-1.4
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS07555
-1.6
-1.2
monovalent cation/H+ antiporter subunit E
compare
MMP
_RS07575
-1.6
-4.2
RNA ligase partner protein
compare
MMP
_RS06020
-1.6
-4.8
archaeoflavoprotein AfpA
compare
MMP
_RS01225
-1.6
-4.7
DUF5379 domain-containing protein
compare
MMP
_RS01800
-1.6
-6.1
TIGR00303 family protein
compare
MMP
_RS05555
-1.6
-2.3
DUF4040 domain-containing protein
compare
MMP
_RS05925
-1.5
-4.3
small nuclear ribonucleoprotein
compare
MMP
_RS08790
-1.5
-3.5
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS07420
-1.5
-5.0
metalloregulator ArsR/SmtB family transcription factor
compare
MMP
_RS04870
-1.5
-4.8
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS05245
-1.5
-8.0
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS03485
-1.5
-5.5
TIGR00267 family protein
compare
MMP
_RS08195
-1.4
-8.4
hypothetical protein
compare
MMP
_RS07710
-1.4
-6.4
cell division protein FtsZ
compare
MMP
_RS02345
-1.4
-3.9
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS09055
-1.4
-1.7
CAP domain-containing protein
compare
MMP
_RS06730
-1.4
-2.1
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS01380
-1.4
-4.7
PHP domain-containing protein
compare
MMP
_RS06170
-1.4
-5.7
ABC transporter ATP-binding protein
compare
MMP
_RS00915
-1.4
-5.2
DUF116 domain-containing protein
compare
MMP
_RS01180
-1.4
-1.8
XTP/dITP diphosphatase
compare
MMP
_RS03770
-1.4
-7.4
hydroxylamine reductase
compare
MMP
_RS01745
-1.3
-5.1
AMP phosphorylase
compare
MMP
_RS06200
-1.3
-8.3
M24 family metallopeptidase
compare
MMP
_RS04685
-1.3
-2.9
DUF126 domain-containing protein
compare
MMP
_RS01575
-1.3
-4.6
aldolase
compare
MMP
_RS06215
-1.3
-4.0
30S ribosomal protein S6e
compare
MMP
_RS05845
-1.3
-3.0
tRNA-intron lyase
compare
MMP
_RS05345
-1.3
-6.0
hypothetical protein
compare
MMP
_RS07380
-1.3
-2.9
transcription elongation factor Spt5
compare
MMP
_RS01725
-1.3
-5.4
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS01250
-1.2
-5.4
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS05550
-1.2
-1.0
cation:proton antiporter
compare
MMP
_RS06475
-1.2
-3.5
FAD-dependent oxidoreductase
compare
MMP
_RS01385
-1.2
-0.9
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS07765
-1.2
-7.7
sodium:alanine symporter family protein
compare
MMP
_RS00110
-1.2
-2.3
hypothetical protein
compare
MMP
_RS07755
-1.2
-1.4
DUF555 domain-containing protein
compare
MMP
_RS08320
-1.1
-6.3
molybdopterin molybdotransferase MoeA
compare
MMP
_RS02135
-1.1
-3.7
DUF5612 domain-containing protein
compare
MMP
_RS01325
-1.1
-3.0
dihydroneopterin aldolase family protein
compare
MMP
_RS06930
-1.1
-7.1
MBL fold metallo-hydrolase
compare
MMP
_RS03080
-1.1
-2.3
universal stress protein
compare
MMP
_RS06230
-1.1
-3.1
helix-turn-helix domain-containing protein
compare
MMP
_RS05425
-1.1
-3.3
monovalent cation/H+ antiporter complex subunit F
compare
MMP
_RS08200
-1.1
-8.2
archaeosine synthase subunit alpha
compare
MMP
_RS07535
-1.1
-6.6
4Fe-4S binding protein
compare
MMP
_RS06675
-1.1
-5.2
ADP-specific phosphofructokinase
compare
MMP
_RS02190
-1.0
-2.4
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS03205
-1.0
-1.7
peptidyl-tRNA hydrolase Pth2
compare
MMP
_RS07685
-1.0
-4.7
TIGR01212 family radical SAM protein
compare
MMP
_RS06895
-1.0
-1.9
selenocysteine-specific translation elongation factor
compare
MMP
_RS01375
-1.0
-7.5
bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase
compare
MMP
_RS00555
-1.0
-4.2
MFS transporter
compare
MMP
_RS00810
-1.0
-4.8
topoisomerase DNA-binding C4 zinc finger domain-containing protein
compare
MMP
_RS04875
-1.0
-3.8
energy-converting hydrogenase B subunit P
compare
MMP
_RS03520
-1.0
-1.6
YwbE family protein
compare
MMP
_RS03155
-1.0
-5.4
precorrin-6A reductase
compare
MMP
_RS02885
-1.0
-7.4
molybdopterin biosynthesis protein
compare
MMP
_RS02145
-1.0
-5.2
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS07705
-1.0
-5.0
transcriptional regulator
compare
MMP
_RS05510
-1.0
-3.8
Rrf2 family transcriptional regulator
compare
MMP
_RS06110
-1.0
-3.1
ATP-dependent protease LonB
compare
MMP
_RS06630
-1.0
-0.9
UPF0058 family protein
compare
MMP
_RS02930
-1.0
-2.2
class I SAM-dependent methyltransferase
compare
MMP
_RS08840
-0.9
-5.0
class I SAM-dependent methyltransferase
compare
MMP
_RS01440
-0.9
-4.1
NAAT family transporter
compare
MMP
_RS06855
-0.9
-5.7
hypothetical protein
compare
MMP
_RS00290
-0.9
-4.0
hypothetical protein
compare
MMP
_RS05545
-0.9
-4.4
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS08690
-0.9
-4.6
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
compare
MMP
_RS08070
-0.9
-4.0
DUF2096 domain-containing protein
compare
MMP
_RS00985
-0.9
-3.1
CDC48 family AAA ATPase
compare
MMP
_RS07200
-0.9
-4.5
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS02175
-0.9
-0.9
DUF1611 domain-containing protein
compare
MMP
_RS06915
-0.9
-4.1
metallophosphoesterase
compare
MMP
_RS00455
-0.9
-5.4
orotate phosphoribosyltransferase-like protein
compare
MMP
_RS03555
-0.9
-4.7
transcriptional regulator
compare
MMP
_RS06865
-0.9
-1.3
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS03590
-0.9
-3.7
METTL5 family protein
compare
MMP
_RS08000
-0.9
-5.9
methyl coenzyme M reductase-arginine methyltransferase Mmp10
compare
MMP
_RS08100
-0.9
-3.4
8-amino-7-oxononanoate synthase
compare
MMP
_RS06165
-0.9
-6.0
ABC transporter permease
compare
MMP
_RS06120
-0.9
-2.0
UPF0147 family protein
compare
MMP
_RS04500
-0.9
-6.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS01750
-0.9
-5.9
DUF63 family protein
compare
MMP
_RS01700
-0.9
-1.1
dihydroxy-acid dehydratase
compare
MMP
_RS07390
-0.9
-1.8
cell division protein FtsZ
compare
MMP
_RS04890
-0.9
-0.9
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS05445
-0.9
-4.0
CoB--CoM heterodisulfide reductase subunit B
compare
MMP
_RS00050
-0.8
-4.0
AarF/UbiB family protein
compare
MMP
_RS06480
-0.8
-6.0
ABC transporter substrate-binding protein
compare
MMP
_RS01830
-0.8
-1.5
tRNA-Val
compare
MMP
_RS06370
-0.8
-2.9
biotin synthase BioB
compare
MMP
_RS03475
-0.8
-0.6
hypothetical protein
compare
MMP
_RS00515
-0.8
-0.9
DUF655 domain-containing protein
compare
MMP
_RS05500
-0.8
-4.8
2-isopropylmalate synthase
compare
MMP
_RS06340
-0.8
-4.2
phosphoadenosine phosphosulfate reductase family protein
compare
Specific Phenotypes
For 1 genes in this experiment