Experiment set6IT022 for Methanococcus maripaludis S2

Compare to:

formate McAA B12 dropout

200 most important genes:

  gene name fitness t score description  
MMP_RS06400 -5.5 -3.3 4Fe-4S binding protein compare
MMP_RS06350 -4.9 -10.9 HesA/MoeB/ThiF family protein compare
MMP_RS01175 -4.8 -7.2 triphosphoribosyl-dephospho-CoA synthase compare
MMP_RS06355 -4.7 -4.3 molybdenum cofactor biosynthesis protein MoaE compare
MMP_RS06700 -4.6 -15.8 hypothetical protein compare
MMP_RS03015 -4.5 -14.3 GTP 3' 8-cyclase MoaA compare
MMP_RS06680 -4.4 -20.1 Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain compare
MMP_RS06685 -4.4 -19.2 formate dehydrogenase H subunit alpha selenocysteine-containing compare
MMP_RS05515 -4.3 -9.4 cyclic pyranopterin monophosphate synthase MoaC compare
MMP_RS06345 -3.8 -17.4 formate dehydrogenase accessory sulfurtransferase FdhD compare
MMP_RS08720 -3.8 -3.6 4Fe-4S binding protein compare
MMP_RS07635 -3.8 -9.4 MogA/MoaB family molybdenum cofactor biosynthesis protein compare
MMP_RS00305 -3.7 -4.0 phosphoribosyl-ATP diphosphatase compare
MMP_RS01755 -3.6 -2.2 DUF2097 domain-containing protein compare
MMP_RS02240 -3.6 -4.9 methanogenesis marker 7 protein compare
MMP_RS07445 -3.4 -7.6 helix-turn-helix domain-containing protein compare
MMP_RS06715 -3.4 -20.7 cache domain-containing protein compare
MMP_RS08300 -3.4 -2.8 metal-sulfur cluster assembly factor compare
MMP_RS01545 -3.2 -2.2 CBS domain-containing protein compare
MMP_RS07525 -3.2 -14.8 4Fe-4S binding protein compare
MMP_RS01500 -3.2 -5.7 CBS domain-containing protein compare
MMP_RS02010 -3.2 -15.4 PHP domain-containing protein compare
MMP_RS04900 -3.2 -23.7 hypothetical protein compare
MMP_RS06720 -3.2 -11.3 response regulator transcription factor compare
MMP_RS01985 -3.1 -9.5 F420-dependent methylenetetrahydromethanopterin dehydrogenase compare
MMP_RS08820 -3.1 -9.5 hypothetical protein compare
MMP_RS02900 -3.0 -1.2 imidazoleglycerol-phosphate dehydratase HisB compare
MMP_RS00040 -3.0 -5.4 TIGR03576 family pyridoxal phosphate-dependent enzyme compare
MMP_RS04605 -3.0 -7.5 cobalt ECF transporter T component CbiQ compare
MMP_RS00695 -3.0 -1.8 biotin--[acetyl-CoA-carboxylase] ligase compare
MMP_RS01020 -2.9 -2.1 3 4-dihydroxy-2-butanone-4-phosphate synthase compare
MMP_RS02355 -2.9 -4.1 30S ribosomal protein S27ae compare
MMP_RS03580 -2.8 -5.9 signal recognition particle-docking protein FtsY compare
MMP_RS06885 -2.8 -5.5 50S ribosome-binding GTPase compare
MMP_RS06705 -2.8 -10.2 formate/nitrite transporter family protein compare
MMP_RS06105 -2.8 -11.1 hydrogenase maturation peptidase HycI compare
MMP_RS08745 -2.8 -8.0 CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase compare
MMP_RS03035 -2.8 -6.2 4-hydroxy-tetrahydrodipicolinate synthase compare
MMP_RS07845 -2.7 -4.0 LL-diaminopimelate aminotransferase compare
MMP_RS04615 -2.7 -5.4 PDGLE domain-containing protein compare
MMP_RS08460 -2.7 -3.6 proteasome-activating nucleotidase compare
MMP_RS06925 -2.7 -3.5 ribonuclease VapC4 compare
MMP_RS01795 -2.7 -3.6 methanogenesis marker 6 protein compare
MMP_RS04585 -2.6 -11.9 AIR synthase related protein compare
MMP_RS08635 -2.6 -3.6 UbiA family prenyltransferase compare
MMP_RS07605 -2.6 -4.5 diadenylate cyclase compare
MMP_RS05920 -2.5 -1.2 50S ribosomal protein L37e compare
MMP_RS07365 -2.5 -14.2 2-phosphoglycerate kinase compare
MMP_RS03435 -2.5 -2.8 ketol-acid reductoisomerase compare
MMP_RS02195 -2.5 -5.0 tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase compare
MMP_RS05765 -2.4 -8.4 M42 family metallopeptidase compare
MMP_RS08210 -2.4 -3.8 phosphatidylglycerophosphatase A compare
MMP_RS01980 -2.4 -16.7 trimeric intracellular cation channel family protein compare
MMP_RS01005 -2.4 -2.5 riboflavin synthase compare
MMP_RS00115 -2.4 -13.1 radical SAM protein compare
MMP_RS01610 -2.4 -4.9 hypothetical protein compare
MMP_RS06270 -2.4 -8.6 TIGR00300 family protein compare
MMP_RS00295 -2.3 -4.8 gamma carbonic anhydrase family protein compare
MMP_RS06285 -2.3 -4.4 precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT compare
MMP_RS00620 -2.3 -8.6 4Fe-4S binding protein compare
MMP_RS04620 -2.3 -11.5 cobalt transporter CbiM compare
MMP_RS02800 -2.3 -7.0 nucleotidyltransferase domain-containing protein compare
MMP_RS02165 -2.3 -13.3 tRNA-dihydrouridine synthase compare
MMP_RS07545 -2.3 -2.3 HTH domain-containing protein compare
MMP_RS07005 -2.3 -1.2 4Fe-4S binding protein compare
MMP_RS03640 -2.2 -5.5 archaeal proteasome endopeptidase complex subunit beta compare
MMP_RS08715 -2.2 -3.0 formylmethanofuran dehydrogenase subunit B compare
MMP_RS02340 -2.2 -4.1 DNA-directed RNA polymerase subunit E'' compare
MMP_RS03445 -2.2 -1.8 methanogenesis marker 17 protein compare
MMP_RS01220 -2.2 -11.7 hypothetical protein compare
MMP_RS04775 -2.2 -4.9 adenosylhomocysteinase compare
MMP_RS08645 -2.2 -8.7 UPF0179 family protein compare
MMP_RS04710 -2.1 -3.4 hypothetical protein compare
MMP_RS08435 -2.1 -3.5 Era-like GTP-binding protein compare
MMP_RS03250 -2.1 -5.1 MJ1244 family protein compare
MMP_RS03025 -2.1 -6.8 molybdenum cofactor guanylyltransferase compare
MMP_RS07730 -2.1 -3.6 pyruvate synthase subunit beta compare
MMP_RS08165 -2.1 -3.3 phosphoglycerate dehydrogenase compare
MMP_RS01665 -2.0 -3.4 DUF2111 domain-containing protein compare
MMP_RS06175 -2.0 -8.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS06295 -2.0 -7.2 methanogenesis marker 14 protein compare
MMP_RS09020 -2.0 -2.9 hypothetical protein compare
MMP_RS06625 -1.9 -3.2 DNA primase compare
MMP_RS00895 -1.9 -7.2 hypothetical protein compare
MMP_RS05875 -1.9 -9.6 hydroxyethylthiazole kinase compare
MMP_RS04780 -1.9 -3.8 ribonuclease P compare
MMP_RS07600 -1.9 -4.0 Ni-sirohydrochlorin a c-diamide synthase compare
MMP_RS01265 -1.9 -3.0 hypothetical protein compare
MMP_RS03400 -1.9 -4.4 archease compare
MMP_RS03600 -1.9 -3.3 triose-phosphate isomerase compare
MMP_RS03315 -1.9 -1.7 ferrous iron transport protein A compare
MMP_RS00685 -1.9 -5.5 2-phospho-L-lactate guanylyltransferase compare
MMP_RS00130 -1.9 -2.3 nickel-responsive transcriptional regulator NikR compare
MMP_RS01365 -1.9 -5.3 archaeal proteasome endopeptidase complex subunit alpha compare
MMP_RS02235 -1.8 -6.5 CBS domain-containing protein compare
MMP_RS07630 -1.8 -2.7 ATP-binding cassette domain-containing protein compare
MMP_RS06975 -1.8 -3.4 sulfide-dependent adenosine diphosphate thiazole synthase compare
MMP_RS05430 -1.8 -5.2 TIGR00288 family NYN domain-containing protein compare
MMP_RS02280 -1.8 -1.6 DUF211 domain-containing protein compare
MMP_RS00300 -1.8 -1.4 6 7-dimethyl-8-ribityllumazine synthase compare
MMP_RS05540 -1.8 -2.8 hypothetical protein compare
MMP_RS07735 -1.8 -1.4 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha compare
MMP_RS07555 -1.6 -1.2 monovalent cation/H+ antiporter subunit E compare
MMP_RS07575 -1.6 -4.2 RNA ligase partner protein compare
MMP_RS06020 -1.6 -4.8 archaeoflavoprotein AfpA compare
MMP_RS01225 -1.6 -4.7 DUF5379 domain-containing protein compare
MMP_RS01800 -1.6 -6.1 TIGR00303 family protein compare
MMP_RS05555 -1.6 -2.3 DUF4040 domain-containing protein compare
MMP_RS05925 -1.5 -4.3 small nuclear ribonucleoprotein compare
MMP_RS08790 -1.5 -3.5 translation initiation factor IF-2 subunit alpha compare
MMP_RS07420 -1.5 -5.0 metalloregulator ArsR/SmtB family transcription factor compare
MMP_RS04870 -1.5 -4.8 TIGR02253 family HAD-type hydrolase compare
MMP_RS05245 -1.5 -8.0 archaeosine biosynthesis radical SAM protein RaSEA compare
MMP_RS03485 -1.5 -5.5 TIGR00267 family protein compare
MMP_RS08195 -1.4 -8.4 hypothetical protein compare
MMP_RS07710 -1.4 -6.4 cell division protein FtsZ compare
MMP_RS02345 -1.4 -3.9 GTP-dependent dephospho-CoA kinase family protein compare
MMP_RS09055 -1.4 -1.7 CAP domain-containing protein compare
MMP_RS06730 -1.4 -2.1 phosphopantothenate/pantothenate synthetase compare
MMP_RS01380 -1.4 -4.7 PHP domain-containing protein compare
MMP_RS06170 -1.4 -5.7 ABC transporter ATP-binding protein compare
MMP_RS00915 -1.4 -5.2 DUF116 domain-containing protein compare
MMP_RS01180 -1.4 -1.8 XTP/dITP diphosphatase compare
MMP_RS03770 -1.4 -7.4 hydroxylamine reductase compare
MMP_RS01745 -1.3 -5.1 AMP phosphorylase compare
MMP_RS06200 -1.3 -8.3 M24 family metallopeptidase compare
MMP_RS04685 -1.3 -2.9 DUF126 domain-containing protein compare
MMP_RS01575 -1.3 -4.6 aldolase compare
MMP_RS06215 -1.3 -4.0 30S ribosomal protein S6e compare
MMP_RS05845 -1.3 -3.0 tRNA-intron lyase compare
MMP_RS05345 -1.3 -6.0 hypothetical protein compare
MMP_RS07380 -1.3 -2.9 transcription elongation factor Spt5 compare
MMP_RS01725 -1.3 -5.4 class I SAM-dependent methyltransferase family protein compare
MMP_RS01250 -1.2 -5.4 tRNA (guanine(26)-N(2))-dimethyltransferase compare
MMP_RS05550 -1.2 -1.0 cation:proton antiporter compare
MMP_RS06475 -1.2 -3.5 FAD-dependent oxidoreductase compare
MMP_RS01385 -1.2 -0.9 imidazole glycerol phosphate synthase subunit HisH compare
MMP_RS07765 -1.2 -7.7 sodium:alanine symporter family protein compare
MMP_RS00110 -1.2 -2.3 hypothetical protein compare
MMP_RS07755 -1.2 -1.4 DUF555 domain-containing protein compare
MMP_RS08320 -1.1 -6.3 molybdopterin molybdotransferase MoeA compare
MMP_RS02135 -1.1 -3.7 DUF5612 domain-containing protein compare
MMP_RS01325 -1.1 -3.0 dihydroneopterin aldolase family protein compare
MMP_RS06930 -1.1 -7.1 MBL fold metallo-hydrolase compare
MMP_RS03080 -1.1 -2.3 universal stress protein compare
MMP_RS06230 -1.1 -3.1 helix-turn-helix domain-containing protein compare
MMP_RS05425 -1.1 -3.3 monovalent cation/H+ antiporter complex subunit F compare
MMP_RS08200 -1.1 -8.2 archaeosine synthase subunit alpha compare
MMP_RS07535 -1.1 -6.6 4Fe-4S binding protein compare
MMP_RS06675 -1.1 -5.2 ADP-specific phosphofructokinase compare
MMP_RS02190 -1.0 -2.4 sulfopyruvate decarboxylase subunit alpha compare
MMP_RS03205 -1.0 -1.7 peptidyl-tRNA hydrolase Pth2 compare
MMP_RS07685 -1.0 -4.7 TIGR01212 family radical SAM protein compare
MMP_RS06895 -1.0 -1.9 selenocysteine-specific translation elongation factor compare
MMP_RS01375 -1.0 -7.5 bifunctional ADP-dependent NAD(P)H-hydrate dehydratase/NAD(P)H-hydrate epimerase compare
MMP_RS00555 -1.0 -4.2 MFS transporter compare
MMP_RS00810 -1.0 -4.8 topoisomerase DNA-binding C4 zinc finger domain-containing protein compare
MMP_RS04875 -1.0 -3.8 energy-converting hydrogenase B subunit P compare
MMP_RS03520 -1.0 -1.6 YwbE family protein compare
MMP_RS03155 -1.0 -5.4 precorrin-6A reductase compare
MMP_RS02885 -1.0 -7.4 molybdopterin biosynthesis protein compare
MMP_RS02145 -1.0 -5.2 winged helix-turn-helix transcriptional regulator compare
MMP_RS07705 -1.0 -5.0 transcriptional regulator compare
MMP_RS05510 -1.0 -3.8 Rrf2 family transcriptional regulator compare
MMP_RS06110 -1.0 -3.1 ATP-dependent protease LonB compare
MMP_RS06630 -1.0 -0.9 UPF0058 family protein compare
MMP_RS02930 -1.0 -2.2 class I SAM-dependent methyltransferase compare
MMP_RS08840 -0.9 -5.0 class I SAM-dependent methyltransferase compare
MMP_RS01440 -0.9 -4.1 NAAT family transporter compare
MMP_RS06855 -0.9 -5.7 hypothetical protein compare
MMP_RS00290 -0.9 -4.0 hypothetical protein compare
MMP_RS05545 -0.9 -4.4 pyridoxal phosphate-dependent aminotransferase compare
MMP_RS08690 -0.9 -4.6 RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5 compare
MMP_RS08070 -0.9 -4.0 DUF2096 domain-containing protein compare
MMP_RS00985 -0.9 -3.1 CDC48 family AAA ATPase compare
MMP_RS07200 -0.9 -4.5 [5-(aminomethyl)furan-3-yl]methyl phosphate kinase compare
MMP_RS02175 -0.9 -0.9 DUF1611 domain-containing protein compare
MMP_RS06915 -0.9 -4.1 metallophosphoesterase compare
MMP_RS00455 -0.9 -5.4 orotate phosphoribosyltransferase-like protein compare
MMP_RS03555 -0.9 -4.7 transcriptional regulator compare
MMP_RS06865 -0.9 -1.3 HypC/HybG/HupF family hydrogenase formation chaperone compare
MMP_RS03590 -0.9 -3.7 METTL5 family protein compare
MMP_RS08000 -0.9 -5.9 methyl coenzyme M reductase-arginine methyltransferase Mmp10 compare
MMP_RS08100 -0.9 -3.4 8-amino-7-oxononanoate synthase compare
MMP_RS06165 -0.9 -6.0 ABC transporter permease compare
MMP_RS06120 -0.9 -2.0 UPF0147 family protein compare
MMP_RS04500 -0.9 -6.7 adenosylmethionine--8-amino-7-oxononanoate transaminase compare
MMP_RS01750 -0.9 -5.9 DUF63 family protein compare
MMP_RS01700 -0.9 -1.1 dihydroxy-acid dehydratase compare
MMP_RS07390 -0.9 -1.8 cell division protein FtsZ compare
MMP_RS04890 -0.9 -0.9 adenylyltransferase/cytidyltransferase family protein compare
MMP_RS05445 -0.9 -4.0 CoB--CoM heterodisulfide reductase subunit B compare
MMP_RS00050 -0.8 -4.0 AarF/UbiB family protein compare
MMP_RS06480 -0.8 -6.0 ABC transporter substrate-binding protein compare
MMP_RS01830 -0.8 -1.5 tRNA-Val compare
MMP_RS06370 -0.8 -2.9 biotin synthase BioB compare
MMP_RS03475 -0.8 -0.6 hypothetical protein compare
MMP_RS00515 -0.8 -0.9 DUF655 domain-containing protein compare
MMP_RS05500 -0.8 -4.8 2-isopropylmalate synthase compare
MMP_RS06340 -0.8 -4.2 phosphoadenosine phosphosulfate reductase family protein compare


Specific Phenotypes

For 1 genes in this experiment