Experiment set6IT021 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with Cisplatin 0.0125 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c11540 +2.0 3.6 gamma-glutamylputrescine synthetase PuuA compare
PGA1_c08590 +1.8 11.7 heme NO binding domain-containing protein compare
PGA1_c08600 +1.7 12.8 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c34880 +1.7 13.5 putative response regulator compare
PGA1_c33190 +1.6 8.0 putative anti-sigma-B factor antagonist compare
PGA1_c34480 +1.4 4.7 UTP--glucose-1-phosphate uridylyltransferase CelA compare
PGA1_78p00140 +1.4 2.1 Sugar phosphate isomerases/epimerases compare
PGA1_c34890 +1.3 10.0 putative histidine-containing phosphotransfer protein compare
PGA1_c07870 +1.3 8.0 alpha-glucoside transport system permease protein AglF compare
PGA1_262p00450 +1.2 3.6 glucose transporter, ATPase component (from data) compare
PGA1_78p00490 +1.2 2.0 putative HTH-type transcriptional regulator compare
PGA1_c00600 +1.2 1.9 putative acetyltransferase compare
PGA1_c00610 +1.2 1.2 acetyltransferase, GNAT family compare
PGA1_c20140 +1.1 6.5 putative arginine-tRNA-protein transferase compare
PGA1_c07860 +1.1 8.1 alpha-glucosides-binding periplasmic protein AglE compare
PGA1_c07880 +1.1 6.9 alpha-glucoside transport system permease protein AglG compare
PGA1_c18380 +1.1 1.5 Phage Head-Tail Attachment. compare
PGA1_c07890 +1.0 6.5 cytoplasmic trehalase (AlgA) (from data) compare
PGA1_c14190 +1.0 5.2 putative transcriptional regulator, AraC family compare
PGA1_c07900 +1.0 5.7 alpha-glucoside transport ATP-binding protein AglK compare
PGA1_c08890 +1.0 3.9 putative capsule polysaccharide export outer membrane protein compare
PGA1_c09260 +0.9 3.3 Uncharacterized conserved protein compare
PGA1_c02460 +0.9 7.6 hypothetical protein compare
PGA1_c12550 +0.9 1.7 hypothetical protein compare
PGA1_c14560 +0.9 2.2 homoserine O-succinyltransferase MetA compare
PGA1_c04010 +0.9 2.3 putative universal stress protein compare
PGA1_c02440 +0.9 6.7 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c02450 +0.9 6.2 putative outer membrane efflux protein compare
PGA1_c34850 +0.8 2.6 putative NUDIX hydrolase compare
PGA1_c01830 +0.8 2.5 Uncharacterized conserved small protein compare
PGA1_c15330 +0.8 2.7 hypothetical protein compare
PGA1_c18600 +0.8 5.0 hypothetical protein compare
PGA1_c18560 +0.8 2.7 hypothetical protein compare
PGA1_c01960 +0.7 2.1 putative hydrolase compare
PGA1_c21580 +0.7 3.2 hypothetical protein compare
PGA1_c08370 +0.7 3.4 Rhodanese-related sulfurtransferase compare
PGA1_65p00450 +0.7 1.6 UDP-glucose 6-dehydrogenase Ugd compare
PGA1_c10210 +0.7 1.6 hypothetical protein compare
PGA1_78p00240 +0.7 1.6 Uncharacterized protein conserved in bacteria compare
PGA1_c24410 +0.7 2.9 hypothetical protein compare
PGA1_262p02170 +0.7 1.7 putative chemoreceptor glutamine deamidase CheD compare
PGA1_c02430 +0.7 3.9 type I secretion membrane fusion protein, HlyD family compare
PGA1_c22860 +0.7 1.8 hypothetical protein compare
PGA1_c09960 +0.7 1.9 putative transcriptional regulator, TetR family compare
PGA1_c31260 +0.7 6.0 Protein of unknown function (DUF3131). compare
PGA1_c35920 +0.7 1.2 thiamine kinase ThiK-like protein compare
PGA1_c34290 +0.7 1.6 peptide methionine sulfoxide reductase MsrA compare
PGA1_c02500 +0.7 2.9 transcriptional regulator, GntR family compare
PGA1_c16420 +0.7 2.0 putative phospholipase / carboxylesterase compare
PGA1_c33170 +0.7 3.2 putative sensor protein compare
PGA1_c36270 +0.7 1.5 hypothetical protein compare
PGA1_c15590 +0.7 5.8 putative transcriptional activator protein compare
PGA1_c29040 +0.7 2.9 endonuclease III compare
PGA1_262p01300 +0.6 1.9 Cupin domain. compare
PGA1_262p00060 +0.6 1.7 putative glycosyl transferase compare
PGA1_262p01780 +0.6 2.0 transcriptional regulator, LysR family compare
PGA1_c26780 +0.6 2.2 cold shock protein CspA compare
PGA1_c31270 +0.6 5.8 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_c16190 +0.6 1.7 hypothetical protein compare
PGA1_c12310 +0.6 4.7 glucans biosynthesis protein G compare
PGA1_c24180 +0.6 2.8 LAO/AO transport system kinase ArgK compare
PGA1_c21900 +0.6 1.8 Uncharacterized conserved small protein compare
PGA1_c01150 +0.6 4.7 transcriptional regulatory protein ChvI compare
PGA1_c10020 +0.6 2.9 Putative protein-S-isoprenylcysteine methyltransferase compare
PGA1_262p01620 +0.6 1.4 Uncharacterized protein conserved in bacteria compare
PGA1_c31880 +0.6 5.5 signal transduction histidine kinase compare
PGA1_262p00660 +0.6 1.7 Predicted periplasmic protein compare
PGA1_c22500 +0.6 1.9 hypothetical protein compare
PGA1_c04730 +0.6 1.1 hypothetical protein compare
PGA1_262p00710 +0.6 0.8 serine/threonine-protein kinase RsbT-like protein compare
PGA1_c15100 +0.6 2.0 tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ compare
PGA1_c19790 +0.6 2.2 putative DNA polymerase III chi subunit, holC compare
PGA1_c23800 +0.6 2.9 hypothetical protein compare
PGA1_c11220 +0.6 4.3 Predicted transcriptional regulators compare
PGA1_c15290 +0.6 2.0 Lactoylglutathione lyase and related lyases compare
PGA1_c14140 +0.6 1.5 hypothetical protein compare
PGA1_c23770 +0.6 2.7 L-serine dehydratase TdcG compare
PGA1_c26620 +0.6 2.7 putative molybdopterin biosynthesis protein MoeB compare
PGA1_c23540 +0.6 2.9 O-succinylhomoserine sulfhydrylase MetZ compare
PGA1_c29740 +0.6 1.1 hypothetical protein compare
PGA1_c02130 +0.6 1.5 conserved hypothetical protein YidD compare
PGA1_c18510 +0.6 2.5 Protein of unknown function (DUF1064). compare
PGA1_c01670 +0.6 2.1 hypothetical protein compare
PGA1_c05170 +0.6 2.0 penicillinase repressor blaI/mecI-like protein compare
PGA1_c26480 +0.6 2.7 Protein involved in catabolism of external DNA compare
PGA1_78p00560 +0.6 1.4 Uncharacterized conserved protein compare
PGA1_c20250 +0.6 2.3 Predicted integral membrane protein compare
PGA1_c14820 +0.5 2.2 hypothetical protein compare
PGA1_262p01540 +0.5 1.2 putative enoyl-CoA hydratase / isomerase compare
PGA1_262p01800 +0.5 1.8 putative membrane dipeptidase compare
PGA1_c23730 +0.5 1.3 hypothetical protein compare
PGA1_262p01680 +0.5 2.1 hypothetical protein compare
PGA1_c14650 +0.5 3.0 hypothetical protein compare
PGA1_c23000 +0.5 1.3 hypothetical protein compare
PGA1_c13050 +0.5 2.1 Zn-dependent hydrolases, including glyoxylases compare
PGA1_c24850 +0.5 1.5 Uncharacterized conserved small protein containing a coiled-coil domain compare
PGA1_c19130 +0.5 1.8 hypothetical protein compare
PGA1_c17720 +0.5 1.2 putative phage cell wall peptidase, NlpC/P60 family compare
PGA1_c11480 +0.5 1.7 Uncharacterized conserved protein compare
PGA1_c11390 +0.5 1.4 putative ATP-dependent RNA helicase RhlE compare
PGA1_c11470 +0.5 1.2 acetyltransferase domain-containing protein compare
PGA1_c06630 +0.5 1.3 hypothetical protein compare
PGA1_262p01450 +0.5 1.9 putative membrane dipeptidase compare
PGA1_262p02130 +0.5 2.6 response regulator receiver compare
PGA1_262p01480 +0.5 1.3 transcriptional regulator, AraC family compare
PGA1_c31930 +0.5 3.4 putative transporter, MFS family compare
PGA1_c05410 +0.5 3.0 hypothetical protein compare
PGA1_78p00500 +0.5 1.4 putative transcriptional regulator compare
PGA1_c28420 +0.5 2.5 putative D,D-dipeptide transport system permease protein compare
PGA1_c05980 +0.5 2.0 Uncharacterized protein conserved in bacteria compare
PGA1_262p01500 +0.5 2.3 sarcosine oxidase subunit alpha compare
PGA1_c19200 +0.5 1.0 Predicted Fe-S protein compare
PGA1_c05400 +0.5 3.4 putative glycosyl transferase, family 2 compare
PGA1_c12190 +0.5 2.3 transcriptional regulator, MarR family compare
PGA1_c01100 +0.5 2.1 Heat shock protein compare
PGA1_c08660 +0.5 1.1 hypothetical protein compare
PGA1_c16780 +0.5 2.0 Uncharacterized conserved protein compare
PGA1_c21110 +0.5 2.5 Protein of unknown function (DUF1185). compare
PGA1_c18630 +0.5 1.1 hypothetical protein compare
PGA1_c29590 +0.5 2.2 hypothetical protein compare
PGA1_c23210 +0.5 1.4 hypothetical protein compare
PGA1_262p00590 +0.5 1.4 Protein of unknown function (DUF2886). compare
PGA1_c15660 +0.5 1.6 enoyl-CoA hydratase/isomerase family protein compare
PGA1_c12090 +0.4 1.3 transcriptional regulator , MerR family compare
PGA1_c11400 +0.4 1.9 ferric uptake regulation protein Fur compare
PGA1_c22680 +0.4 1.3 Arc-like DNA binding domain. compare
PGA1_c05370 +0.4 3.9 polyketide synthase compare
PGA1_c14770 +0.4 2.0 tRNA-dihydrouridine synthase DusB compare
PGA1_c05310 +0.4 2.9 putative glycosyl transferase compare
PGA1_c12320 +0.4 1.7 Uncharacterized protein conserved in bacteria compare
PGA1_c12580 +0.4 1.4 Uncharacterized protein conserved in bacteria (DUF2155). compare
PGA1_262p01600 +0.4 0.8 putative ABC transporter, ATP binding protein compare
PGA1_c34120 +0.4 1.1 HTH-type transcriptional regulator PetP compare
PGA1_c13890 +0.4 1.5 Predicted enzyme related to lactoylglutathione lyase compare
PGA1_c18900 +0.4 1.0 Uncharacterized conserved protein compare
PGA1_c13430 +0.4 1.4 C4-dicarboxylate transport sensor protein DctB compare
PGA1_c12300 +0.4 2.8 glucans biosynthesis glucosyltransferase H compare
PGA1_c20480 +0.4 0.9 tRNA-Val compare
PGA1_c32560 +0.4 1.9 high-affinity branched-chain amino acid transport ATP-binding protein compare
PGA1_c26560 +0.4 1.9 Predicted dioxygenase of extradiol dioxygenase family compare
PGA1_c02540 +0.4 2.2 Uncharacterized conserved protein compare
PGA1_c24110 +0.4 1.3 hypothetical protein compare
PGA1_262p00870 +0.4 1.6 ABC transporter, extracellular solute-binding protein compare
PGA1_c18280 +0.4 2.0 hypothetical protein compare
PGA1_c21050 +0.4 1.3 glutaredoxin-like protein compare
PGA1_262p01010 +0.4 1.8 dipeptide transport ATP-binding protein DppD compare
PGA1_c16920 +0.4 0.6 molybdenum cofactor biosynthesis protein C compare
PGA1_c15670 +0.4 2.3 putative beta-lactamase compare
PGA1_c01160 +0.4 3.4 sensor protein ChvG compare
PGA1_c15070 +0.4 1.8 Nickel uptake substrate-specific transmembrane region. compare
PGA1_c07720 +0.4 1.7 universal stress protein compare
PGA1_c16210 +0.4 1.0 iron-sulfur cluster binding domain-containing protein compare
PGA1_c10930 +0.4 2.7 hypothetical protein compare
PGA1_c12420 +0.4 1.9 cytochrome c SoxX compare
PGA1_c15870 +0.4 1.5 transcriptional regulator, AraC family compare
PGA1_c29440 +0.4 1.8 hypothetical protein compare
PGA1_c19640 +0.4 1.5 transcriptional regulator, containing response regulator domain compare
PGA1_262p00750 +0.4 1.2 Threonine dehydratase compare
PGA1_c31170 +0.4 1.4 phosphotyrosine protein phosphatase-like protein compare
PGA1_c04090 +0.4 2.1 beta-ketoadipyl-CoA thiolase PaaJ compare
PGA1_c27840 +0.4 2.0 putative polysaccharide biosynthesis protein compare
PGA1_78p00170 +0.4 0.8 putative sn-glycerol-3-phosphate transport system permease protein UgpA compare
PGA1_c11490 +0.4 1.9 pyrimidine-specific ribonucleoside hydrolase RihA compare
PGA1_c05720 +0.4 1.5 hypothetical protein compare
PGA1_c08710 +0.4 2.1 TadE-like protein. compare
PGA1_c12050 +0.4 1.6 putative glutathione S-transferase compare
PGA1_c11710 +0.4 1.7 transcriptional regulator, LysR family compare
PGA1_c07060 +0.4 1.7 YtoQ family protein compare
PGA1_c26950 +0.4 1.2 putative exopolysaccharide synthesis protein ExoD compare
PGA1_c26850 +0.4 0.9 Predicted metal-binding protein compare
PGA1_262p00610 +0.4 0.5 metallophosphoesterase compare
PGA1_c08830 +0.4 1.8 hypothetical protein compare
PGA1_c19980 +0.4 1.8 hypothetical protein compare
PGA1_262p00840 +0.4 1.8 hypothetical protein compare
PGA1_c18520 +0.4 1.5 Uncharacterized protein conserved in bacteria compare
PGA1_c05390 +0.4 1.4 glycosyl transferase compare
PGA1_c16040 +0.4 1.4 Methionine synthase component, pterin-binding domain (EC:2.1.1.13) (from data) compare
PGA1_c17590 +0.4 2.0 hypothetical protein compare
PGA1_262p00370 +0.4 1.2 putative polysaccharide synthase compare
PGA1_c09590 +0.4 1.9 uncharacterized protein YhiN compare
PGA1_c15610 +0.4 2.0 alcohol dehydrogenase, zinc binding compare
PGA1_262p00420 +0.4 1.6 Transcriptional regulator/sugar kinase compare
PGA1_c27130 +0.4 2.2 putative HTH-type transcriptional regulator compare
PGA1_c31920 +0.4 1.3 thioeseterase-like protein compare
PGA1_c30660 +0.4 1.5 putative addiction module antidote protein, HigA family compare
PGA1_c16540 +0.4 1.9 putative branched-chain amino acid transport system, permease component compare
PGA1_c34420 +0.4 2.4 putrescine-binding periplasmic protein PotF compare
PGA1_c29750 +0.4 1.8 putative ribosomal RNA large subunit methyltransferase compare
PGA1_c22750 +0.4 2.2 hypothetical protein compare
PGA1_c18660 +0.4 1.6 hypothetical protein compare
PGA1_c32010 +0.4 1.7 isopentenyl-diphosphate delta-isomerase Idi compare
PGA1_c29670 +0.4 1.2 small heat shock protein IbpA compare
PGA1_c15310 +0.4 1.6 multidrug transporter EmrE compare
PGA1_c05180 +0.4 1.4 Predicted small integral membrane protein compare
PGA1_c11360 +0.3 2.1 Uncharacterized conserved protein compare
PGA1_262p01110 +0.3 1.1 hypothetical protein compare
PGA1_c36400 +0.3 1.9 hypothetical protein compare
PGA1_262p01700 +0.3 1.5 putative ABC transporter, solute-binding protein compare
PGA1_c34190 +0.3 1.6 methyltransferase-like protein compare
PGA1_c08780 +0.3 0.9 hypothetical protein compare


Specific Phenotypes

For 10 genes in this experiment

For stress Cisplatin in Phaeobacter inhibens DSM 17395

For stress Cisplatin across organisms