Experiment set6IT021 for Klebsiella michiganensis M5al

Compare to:

D-Alanine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.0 -3.4 histidinol-phosphate transaminase compare
BWI76_RS04160 -8.8 -5.0 phosphoserine phosphatase compare
BWI76_RS20965 -8.6 -3.2 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS20355 -8.5 -3.3 colicin V production protein compare
BWI76_RS18935 -8.5 -4.8 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00805 -8.3 -3.6 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS07065 -8.1 -4.6 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS18950 -8.0 -3.5 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21465 -7.7 -3.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS04470 -7.6 -5.3 carbamoyl phosphate synthase large subunit compare
BWI76_RS01210 -7.5 -2.9 tyrosine recombinase XerC compare
BWI76_RS02995 -7.5 -6.8 aspartate carbamoyltransferase compare
BWI76_RS11855 -7.4 -6.0 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS01655 -7.4 -6.1 homoserine O-succinyltransferase compare
BWI76_RS00845 -7.3 -5.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS23920 -7.2 -3.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS04465 -7.2 -3.8 carbamoyl-phosphate synthase small subunit compare
BWI76_RS23365 -7.2 -2.9 LysR family transcriptional regulator compare
BWI76_RS04250 -7.2 -6.3 homoserine kinase compare
BWI76_RS25115 -7.1 -5.7 argininosuccinate synthase compare
BWI76_RS00990 -7.0 -6.1 ketol-acid reductoisomerase compare
BWI76_RS23220 -6.9 -6.2 amino-acid N-acetyltransferase compare
BWI76_RS18940 -6.9 -3.3 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18920 -6.9 -3.0 ATP phosphoribosyltransferase compare
BWI76_RS00785 -6.8 -4.7 cystathionine gamma-synthase compare
BWI76_RS00390 -6.8 -4.0 two-component system sensor histidine kinase NtrB compare
BWI76_RS27385 -6.8 -4.7 orotate phosphoribosyltransferase compare
BWI76_RS05835 -6.7 -3.0 gamma-glutamyl-phosphate reductase compare
BWI76_RS00855 -6.7 -6.5 argininosuccinate lyase compare
BWI76_RS11850 -6.7 -9.3 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS25315 -6.7 -11.1 glutamate synthase large subunit compare
BWI76_RS04255 -6.6 -7.9 threonine synthase compare
BWI76_RS11965 -6.4 -3.5 orotidine-5'-phosphate decarboxylase compare
BWI76_RS01615 -6.4 -8.8 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS04670 -6.3 -8.8 3-isopropylmalate dehydratase large subunit compare
BWI76_RS19850 -6.3 -2.4 tRNA-Pro compare
BWI76_RS11105 -6.2 -2.3 aminodeoxychorismate lyase compare
BWI76_RS00850 -6.2 -6.8 acetylglutamate kinase compare
BWI76_RS09755 -6.2 -4.6 phosphoserine transaminase compare
BWI76_RS08385 -6.1 -2.2 citrate (Si)-synthase compare
BWI76_RS25320 -6.0 -9.5 glutamate synthase compare
BWI76_RS04245 -5.8 -11.7 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS11860 -5.7 -5.9 anthranilate synthase component I compare
BWI76_RS04665 -5.7 -19.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS00385 -5.6 -7.0 nitrogen assimilation regulatory protein compare
BWI76_RS04510 -5.6 -2.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) compare
BWI76_RS04645 -5.5 -5.6 3-dehydroquinase compare
BWI76_RS11840 -5.5 -1.9 tryptophan synthase subunit alpha compare
BWI76_RS21265 -5.5 -8.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26085 -5.4 -2.1 3-dehydroquinate synthase compare
BWI76_RS24285 -5.3 -5.4 cystathionine beta-lyase compare
BWI76_RS17735 -5.2 -4.1 D-amino acid dehydrogenase small subunit conserved
BWI76_RS15975 -5.2 -1.1 hypothetical protein compare
BWI76_RS12090 -5.2 -1.8 HNH endonuclease compare
BWI76_RS08110 -5.1 -2.2 glutamate/aspartate ABC transporter substrate-binding protein compare
BWI76_RS04685 -5.1 -8.3 putative leucine operon leader peptide compare
BWI76_RS11335 -5.1 -1.1 tautomerase compare
BWI76_RS27390 -5.1 -3.5 ribonuclease PH compare
BWI76_RS10990 -5.0 -1.8 dihydroorotase compare
BWI76_RS20350 -4.9 -4.5 amidophosphoribosyltransferase compare
BWI76_RS00965 -4.9 -1.1 acetolactate synthase 2 small subunit compare
BWI76_RS24945 -4.9 -1.1 glutamine amidotransferase compare
BWI76_RS03010 -4.8 -5.8 ornithine carbamoyltransferase compare
BWI76_RS22805 -4.8 -8.0 GTP diphosphokinase compare
BWI76_RS13095 -4.7 -1.5 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS00835 -4.7 -9.4 phosphoenolpyruvate carboxylase compare
BWI76_RS04680 -4.7 -8.7 2-isopropylmalate synthase compare
BWI76_RS09315 -4.7 -1.5 hypothetical protein compare
BWI76_RS21310 -4.6 -1.0 DNA repair protein RecO compare
BWI76_RS18770 -4.6 -1.0 DNA gyrase inhibitor compare
BWI76_RS26620 -4.6 -1.0 Fe-S biogenesis protein NfuA compare
BWI76_RS09910 -4.6 -12.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS00400 -4.5 -1.7 glutamine synthetase compare
BWI76_RS07070 -4.5 -4.3 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS25645 -4.5 -6.6 shikimate dehydrogenase compare
BWI76_RS00980 -4.4 -7.7 PLP-dependent threonine dehydratase compare
BWI76_RS05840 -4.4 -3.9 glutamate 5-kinase compare
BWI76_RS01350 -4.4 -1.0 NAD(P)H-flavin reductase compare
BWI76_RS04240 -4.3 -1.2 thr operon leader peptide compare
BWI76_RS21475 -4.2 -3.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS18240 -4.2 -1.3 L-arabinose ABC transporter permease AraH compare
BWI76_RS26410 -4.1 -1.3 membrane protein compare
BWI76_RS23230 -4.0 -2.8 exodeoxyribonuclease V subunit beta compare
BWI76_RS18925 -4.0 -5.1 histidinol dehydrogenase compare
BWI76_RS04675 -4.0 -3.1 3-isopropylmalate dehydrogenase compare
BWI76_RS01610 -4.0 -5.4 phosphoribosylamine--glycine ligase compare
BWI76_RS19935 -4.0 -1.2 hypothetical protein compare
BWI76_RS05200 -3.9 -2.2 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS00975 -3.8 -5.8 dihydroxy-acid dehydratase compare
BWI76_RS09760 -3.8 -2.1 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS23240 -3.8 -3.7 exonuclease V subunit gamma compare
BWI76_RS08720 -3.6 -2.0 imidazolonepropionase compare
BWI76_RS11845 -3.6 -2.1 tryptophan synthase subunit beta compare
BWI76_RS04565 -3.6 -2.7 bifunctional tRNA pseudouridine(32) synthase/ribosomal large subunit pseudouridine synthase RluA compare
BWI76_RS10575 -3.5 -1.1 polar amino acid ABC transporter permease compare
BWI76_RS20895 -3.5 -2.5 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS17190 -3.4 -2.4 TonB system transport protein TonB compare
BWI76_RS21675 -3.3 -1.0 hypothetical protein compare
BWI76_RS23140 -3.3 -0.9 carboxysome shell protein compare
BWI76_RS18955 -3.2 -2.3 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04305 -3.2 -1.0 molecular chaperone DnaJ compare
BWI76_RS22690 -3.1 -3.0 adenylyl-sulfate kinase compare
BWI76_RS15835 -3.1 -2.0 hypothetical protein compare
BWI76_RS09530 -3.1 -1.0 hypothetical protein compare
BWI76_RS15685 -3.0 -1.6 hypothetical protein compare
BWI76_RS20710 -2.9 -2.8 dyp-type peroxidase family protein compare
BWI76_RS22840 -2.9 -1.4 transposase compare
BWI76_RS15360 -2.8 -2.3 hypothetical protein compare
BWI76_RS21165 -2.8 -1.2 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS14415 -2.8 -2.6 transcriptional regulator, TetR family protein compare
BWI76_RS21130 -2.8 -1.5 Fe-S assembly protein IscX compare
BWI76_RS02410 -2.8 -1.5 EF-P beta-lysylation protein EpmB compare
BWI76_RS23360 -2.8 -2.6 diaminopimelate decarboxylase compare
BWI76_RS20435 -2.8 -0.8 chorismate synthase compare
BWI76_RS01200 -2.7 -1.8 diaminopimelate epimerase compare
BWI76_RS16955 -2.7 -0.8 hypothetical protein compare
BWI76_RS17525 -2.6 -1.4 XshC-Cox1-family protein compare
BWI76_RS11895 -2.6 -1.8 AraC family transcriptional regulator compare
BWI76_RS15605 -2.6 -1.4 hypothetical protein compare
BWI76_RS05120 -2.6 -4.1 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS23480 -2.5 -7.7 EAL domain-containing protein compare
BWI76_RS25205 -2.5 -1.7 hypothetical protein compare
BWI76_RS21075 -2.5 -1.3 membrane protein compare
BWI76_RS11535 -2.4 -2.2 putative oxidoreductase, Zn-dependent and NAD(P)-binding protein compare
BWI76_RS21140 -2.4 -1.6 molecular chaperone HscA compare
BWI76_RS05015 -2.4 -1.4 transcriptional regulator compare
BWI76_RS24465 -2.4 -6.8 adenylate cyclase compare
BWI76_RS21340 -2.3 -2.0 SoxR reducing system protein RseC compare
BWI76_RS15825 -2.3 -1.2 hypothetical protein compare
BWI76_RS12150 -2.3 -3.0 DNA damage-inducible protein I compare
BWI76_RS06080 -2.3 -1.5 taurine dioxygenase compare
BWI76_RS10035 -2.3 -1.1 hypothetical protein compare
BWI76_RS06525 -2.3 -3.1 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS02735 -2.2 -2.7 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS22755 -2.2 -3.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS26150 -2.2 -2.3 molecular chaperone Hsp33 compare
BWI76_RS13170 -2.2 -2.8 methyltransferase compare
BWI76_RS22760 -2.1 -4.4 sulfite reductase subunit beta compare
BWI76_RS17300 -2.1 -0.9 tRNA-Tyr compare
BWI76_RS00960 -2.1 -3.4 acetolactate synthase 2 catalytic subunit compare
BWI76_RS21370 -2.1 -1.5 ATP-dependent RNA helicase SrmB compare
BWI76_RS26455 -2.0 -2.1 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS06530 -2.0 -2.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS05025 -2.0 -2.4 2'-5' RNA ligase compare
BWI76_RS00345 -2.0 -2.8 protein disulfide oxidoreductase DsbA compare
BWI76_RS24500 -1.9 -1.8 urease subunit gamma compare
BWI76_RS18695 -1.9 -3.7 GntR family transcriptional regulator compare
BWI76_RS04705 -1.9 -3.7 DNA-binding transcriptional regulator FruR compare
BWI76_RS13645 -1.9 -1.3 N-hydroxyarylamine O-acetyltransferase compare
BWI76_RS04715 -1.9 -1.4 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS25935 -1.9 -1.4 glutathione-regulated potassium-efflux system ancillary protein KefG compare
BWI76_RS08525 -1.9 -2.1 colicin transporter compare
BWI76_RS08180 -1.9 -4.3 asparagine synthase B compare
BWI76_RS07965 -1.8 -3.4 anaerobic C4-dicarboxylate transporter DcuC compare
BWI76_RS25925 -1.8 -1.3 hypothetical protein compare
BWI76_RS01205 -1.8 -1.3 DUF484 family protein compare
BWI76_RS01995 -1.8 -0.9 AraC family transcriptional regulator compare
BWI76_RS09655 -1.8 -2.4 leucine-responsive regulatory protein compare
BWI76_RS01540 -1.8 -1.3 thiamine biosynthesis protein ThiS compare
BWI76_RS00985 -1.8 -3.2 transcriptional regulator IlvY compare
BWI76_RS02655 -1.8 -1.3 hypothetical protein compare
BWI76_RS05005 -1.8 -1.5 polynucleotide adenylyltransferase compare
BWI76_RS20900 -1.7 -1.0 outer membrane protein assembly factor BamC compare
BWI76_RS14170 -1.7 -1.7 hypothetical protein compare
BWI76_RS15485 -1.7 -3.4 putative universal stress protein G compare
BWI76_RS23265 -1.7 -1.4 hypothetical protein compare
BWI76_RS25280 -1.7 -1.1 RNase adaptor protein RapZ compare
BWI76_RS19010 -1.7 -1.9 polysaccharide pyruvyl transferase yvff compare
BWI76_RS18165 -1.7 -1.0 NUDIX pyrophosphatase compare
BWI76_RS09490 -1.7 -1.4 DNA-binding response regulator compare
BWI76_RS22270 -1.6 -2.3 nickel transporter compare
BWI76_RS23560 -1.6 -1.6 hypothetical protein compare
BWI76_RS09190 -1.6 -2.3 hypothetical protein compare
BWI76_RS17720 -1.6 -0.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS25070 -1.6 -0.9 hypothetical protein compare
BWI76_RS16905 -1.6 -2.1 acetaldehyde dehydrogenase (acetylating) compare
BWI76_RS26875 -1.6 -1.3 dipeptide ABC transporter permease DppC compare
BWI76_RS13245 -1.6 -1.6 DNA-damage-inducible protein I compare
BWI76_RS13180 -1.6 -1.2 multidrug transporter EmrA compare
BWI76_RS10825 -1.6 -1.9 deferrochelatase/peroxidase EfeB compare
BWI76_RS02680 -1.6 -1.3 EamA family transporter compare
BWI76_RS19585 -1.6 -1.5 gentisate 1,2-dioxygenase compare
BWI76_RS13820 -1.5 -1.3 hypothetical protein compare
BWI76_RS20690 -1.5 -2.1 sulfate ABC transporter ATP-binding protein compare
BWI76_RS14435 -1.5 -1.1 glutamine ABC transporter ATP-binding protein compare
BWI76_RS02990 -1.5 -1.9 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS16965 -1.5 -1.9 murein lipoprotein compare
BWI76_RS24940 -1.5 -2.3 hypothetical protein compare
BWI76_RS16555 -1.5 -1.6 hypothetical protein compare
BWI76_RS22090 -1.5 -1.4 transcriptional regulator compare
BWI76_RS04570 -1.5 -2.6 RNA polymerase-associated protein RapA compare
BWI76_RS14820 -1.5 -1.1 LysR family transcriptional regulator compare
BWI76_RS20695 -1.5 -1.8 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS25000 -1.5 -0.9 malonate decarboxylase acyl carrier protein compare
BWI76_RS18535 -1.5 -2.1 alpha/beta hydrolase compare
BWI76_RS15670 -1.5 -2.8 hypothetical protein compare
BWI76_RS13420 -1.5 -1.2 ABC transporter permease compare
BWI76_RS18455 -1.5 -0.7 tRNA-Ser compare
BWI76_RS24350 -1.5 -2.0 quinol monooxygenase compare
BWI76_RS06490 -1.5 -2.5 cytochrome ubiquinol oxidase subunit I compare


Specific Phenotypes

For 2 genes in this experiment

For nitrogen source D-Alanine in Klebsiella michiganensis M5al

For nitrogen source D-Alanine across organisms