Experiment set6IT020 for Klebsiella michiganensis M5al

Compare to:

D-Serine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18930 -9.0 -4.4 histidinol-phosphate transaminase compare
BWI76_RS11850 -8.4 -5.8 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS00805 -8.3 -4.7 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS11965 -8.2 -4.7 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18955 -8.0 -5.0 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS04250 -7.9 -5.5 homoserine kinase compare
BWI76_RS04670 -7.6 -5.3 3-isopropylmalate dehydratase large subunit compare
BWI76_RS18925 -7.5 -4.3 histidinol dehydrogenase compare
BWI76_RS01655 -7.5 -7.3 homoserine O-succinyltransferase compare
BWI76_RS11860 -7.4 -7.2 anthranilate synthase component I compare
BWI76_RS00850 -7.3 -8.9 acetylglutamate kinase compare
BWI76_RS18935 -7.2 -6.7 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00980 -7.1 -8.5 PLP-dependent threonine dehydratase compare
BWI76_RS04685 -7.1 -4.9 putative leucine operon leader peptide compare
BWI76_RS20895 -7.0 -4.8 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS24285 -7.0 -6.8 cystathionine beta-lyase compare
BWI76_RS18920 -6.9 -4.0 ATP phosphoribosyltransferase compare
BWI76_RS18940 -6.9 -4.2 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00785 -6.9 -4.8 cystathionine gamma-synthase compare
BWI76_RS04245 -6.8 -10.4 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS07070 -6.8 -4.5 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00855 -6.8 -6.6 argininosuccinate lyase compare
BWI76_RS05835 -6.7 -3.8 gamma-glutamyl-phosphate reductase compare
BWI76_RS20355 -6.5 -3.6 colicin V production protein compare
BWI76_RS04470 -6.5 -8.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS23220 -6.4 -8.5 amino-acid N-acetyltransferase compare
BWI76_RS05840 -6.3 -4.4 glutamate 5-kinase compare
BWI76_RS20350 -6.2 -5.6 amidophosphoribosyltransferase compare
BWI76_RS21265 -6.0 -14.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS04675 -6.0 -7.1 3-isopropylmalate dehydrogenase compare
BWI76_RS11840 -5.8 -2.4 tryptophan synthase subunit alpha compare
BWI76_RS02995 -5.7 -8.6 aspartate carbamoyltransferase compare
BWI76_RS23360 -5.7 -3.1 diaminopimelate decarboxylase compare
BWI76_RS05015 -5.5 -3.2 transcriptional regulator compare
BWI76_RS00835 -5.5 -12.8 phosphoenolpyruvate carboxylase compare
BWI76_RS04680 -5.4 -12.3 2-isopropylmalate synthase compare
BWI76_RS04665 -5.3 -17.7 3-isopropylmalate dehydratase small subunit compare
BWI76_RS09760 -5.3 -3.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS27385 -5.3 -7.3 orotate phosphoribosyltransferase compare
BWI76_RS25115 -5.3 -5.5 argininosuccinate synthase compare
BWI76_RS00990 -5.2 -6.0 ketol-acid reductoisomerase compare
BWI76_RS23365 -5.2 -4.7 LysR family transcriptional regulator compare
BWI76_RS25320 -5.2 -7.2 glutamate synthase compare
BWI76_RS00845 -5.2 -7.4 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS04255 -5.2 -10.4 threonine synthase compare
BWI76_RS11855 -5.2 -5.1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS00985 -5.1 -6.4 transcriptional regulator IlvY compare
BWI76_RS25315 -5.1 -9.6 glutamate synthase large subunit compare
BWI76_RS17720 -5.0 -1.4 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS09910 -5.0 -16.8 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS10990 -5.0 -2.3 dihydroorotase compare
BWI76_RS21475 -4.9 -4.9 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS07065 -4.9 -5.7 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11845 -4.9 -1.6 tryptophan synthase subunit beta compare
BWI76_RS00965 -4.9 -1.4 acetolactate synthase 2 small subunit compare
BWI76_RS09615 -4.8 -2.7 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS01610 -4.8 -6.2 phosphoribosylamine--glycine ligase compare
BWI76_RS02735 -4.7 -3.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS24485 -4.6 -1.9 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS00400 -4.6 -2.2 glutamine synthetase compare
BWI76_RS25285 -4.6 -1.3 HPr family phosphocarrier protein compare
BWI76_RS04645 -4.6 -4.8 3-dehydroquinase compare
BWI76_RS24080 -4.5 -2.2 DUF179 domain-containing protein compare
BWI76_RS22765 -4.5 -9.6 sulfite reductase subunit alpha compare
BWI76_RS01350 -4.4 -1.3 NAD(P)H-flavin reductase compare
BWI76_RS22805 -4.4 -6.6 GTP diphosphokinase compare
BWI76_RS21465 -4.3 -3.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS06680 -4.3 -1.2 hypothetical protein compare
BWI76_RS04240 -4.3 -1.5 thr operon leader peptide compare
BWI76_RS20965 -4.3 -2.7 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS01615 -4.2 -6.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS14390 -4.1 -1.6 hypothetical protein compare
BWI76_RS22755 -4.1 -7.5 phosphoadenosine phosphosulfate reductase compare
BWI76_RS27390 -4.1 -3.1 ribonuclease PH compare
BWI76_RS08385 -4.1 -3.7 citrate (Si)-synthase compare
BWI76_RS04465 -4.1 -4.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09755 -4.0 -6.2 phosphoserine transaminase compare
BWI76_RS03010 -3.9 -6.0 ornithine carbamoyltransferase compare
BWI76_RS00025 -3.9 -1.1 hypothetical protein compare
BWI76_RS00385 -3.8 -5.4 nitrogen assimilation regulatory protein compare
BWI76_RS09660 -3.8 -2.4 DNA translocase FtsK compare
BWI76_RS26055 -3.7 -7.7 siroheme synthase compare
BWI76_RS00975 -3.7 -5.9 dihydroxy-acid dehydratase compare
BWI76_RS22760 -3.7 -5.2 sulfite reductase subunit beta compare
BWI76_RS21140 -3.6 -2.9 molecular chaperone HscA compare
BWI76_RS20720 -3.6 -1.5 hypothetical protein compare
BWI76_RS04160 -3.5 -3.8 phosphoserine phosphatase compare
BWI76_RS03665 -3.5 -2.0 ABC transporter ATP-binding protein compare
BWI76_RS26000 -3.4 -5.0 aspartate aminotransferase family protein compare
BWI76_RS23920 -3.4 -2.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS25645 -3.4 -6.4 shikimate dehydrogenase compare
BWI76_RS23240 -3.3 -4.2 exonuclease V subunit gamma compare
BWI76_RS18950 -3.3 -1.8 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS21810 -3.1 -1.3 universal stress protein compare
BWI76_RS17530 -3.1 -3.2 hypothetical protein compare
BWI76_RS27855 -3.0 -4.4 D-serine transporter DsdX compare
BWI76_RS25425 -3.0 -1.7 arginine repressor compare
BWI76_RS10910 -3.0 -2.6 hypothetical protein compare
BWI76_RS09195 -2.9 -1.7 N-acetyltransferase compare
BWI76_RS25920 -2.9 -1.8 peptidylprolyl isomerase compare
BWI76_RS27860 -2.8 -7.2 D-serine dehydratase conserved
BWI76_RS20435 -2.8 -1.1 chorismate synthase compare
BWI76_RS22690 -2.7 -1.8 adenylyl-sulfate kinase compare
BWI76_RS24900 -2.7 -2.2 DeoR family transcriptional regulator compare
BWI76_RS00390 -2.6 -5.2 two-component system sensor histidine kinase NtrB compare
BWI76_RS24260 -2.6 -2.5 hypothetical protein compare
BWI76_RS02580 -2.6 -1.6 23S rRNA (guanosine(2251)-2'-O)-methyltransferase compare
BWI76_RS20640 -2.6 -3.2 cysteine synthase A compare
BWI76_RS09655 -2.5 -3.4 leucine-responsive regulatory protein compare
BWI76_RS08535 -2.5 -2.3 translocation protein TolB compare
BWI76_RS20970 -2.4 -1.4 phosphoribosylglycinamide formyltransferase compare
BWI76_RS14915 -2.4 -2.5 hypothetical protein compare
BWI76_RS26085 -2.4 -1.5 3-dehydroquinate synthase compare
BWI76_RS27850 -2.4 -2.4 DNA-binding transcriptional regulator DsdC conserved
BWI76_RS20440 -2.4 -1.7 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS25485 -2.4 -1.5 septum formation protein Maf compare
BWI76_RS23230 -2.3 -3.7 exodeoxyribonuclease V subunit beta compare
BWI76_RS14305 -2.3 -2.4 metallophosphoesterase compare
BWI76_RS09650 -2.2 -5.5 hypothetical protein compare
BWI76_RS01200 -2.2 -1.9 diaminopimelate epimerase compare
BWI76_RS00960 -2.2 -2.7 acetolactate synthase 2 catalytic subunit compare
BWI76_RS22700 -2.2 -3.3 sulfate adenylyltransferase subunit 2 compare
BWI76_RS19010 -2.2 -2.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS07985 -2.1 -1.0 fluoride ion transporter CrcB compare
BWI76_RS05200 -2.1 -2.3 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS15215 -2.1 -1.2 N-acetyltransferase compare
BWI76_RS21450 -2.1 -2.5 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS21375 -2.1 -1.6 autonomous glycyl radical cofactor GrcA compare
BWI76_RS13970 -2.0 -1.8 ABC transporter compare
BWI76_RS19690 -2.0 -2.5 LysR family transcriptional regulator compare
BWI76_RS21565 -2.0 -1.1 outer membrane protein assembly factor BamE compare
BWI76_RS02530 -2.0 -1.8 tRNA dimethylallyltransferase compare
BWI76_RS16965 -1.9 -3.9 murein lipoprotein compare
BWI76_RS21070 -1.9 -1.9 outer membrane protein assembly factor BamB compare
BWI76_RS14415 -1.9 -2.2 transcriptional regulator, TetR family protein compare
BWI76_RS09530 -1.9 -1.1 hypothetical protein compare
BWI76_RS25065 -1.8 -1.9 polyribonucleotide nucleotidyltransferase compare
BWI76_RS21480 -1.8 -2.9 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS06525 -1.8 -2.5 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS02990 -1.8 -1.7 aspartate carbamoyltransferase regulatory subunit compare
BWI76_RS27425 -1.8 -1.8 DNA-directed RNA polymerase subunit omega compare
BWI76_RS01095 -1.8 -1.5 UDP-N-acetyl-D-mannosamine dehydrogenase compare
BWI76_RS06535 -1.8 -3.0 endopeptidase La compare
BWI76_RS06530 -1.7 -2.6 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS09450 -1.7 -1.7 30S ribosomal protein S6--L-glutamate ligase compare
BWI76_RS14005 -1.7 -1.6 TetR family transcriptional regulator compare
BWI76_RS19215 -1.7 -1.4 proline-specific peptidase compare
BWI76_RS11700 -1.7 -1.2 hypothetical protein compare
BWI76_RS10465 -1.7 -1.7 hypothetical protein compare
BWI76_RS05120 -1.6 -4.4 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS05465 -1.6 -1.0 amidohydrolase compare
BWI76_RS01885 -1.6 -1.0 CsbD family protein compare
BWI76_RS06765 -1.6 -1.6 transcriptional regulator compare
BWI76_RS09645 -1.6 -1.0 thioredoxin-disulfide reductase compare
BWI76_RS13560 -1.6 -1.0 amino acid ABC transporter substrate-binding subunit compare
BWI76_RS11430 -1.6 -1.0 lipoprotein compare
BWI76_RS20035 -1.6 -2.6 hypothetical protein compare
BWI76_RS25335 -1.6 -2.0 stringent starvation protein A compare
BWI76_RS09315 -1.6 -1.2 hypothetical protein compare
BWI76_RS13250 -1.6 -1.1 cytochrome b561 compare
BWI76_RS10835 -1.6 -1.1 hypothetical protein compare
BWI76_RS21660 -1.5 -1.3 antirestriction protein compare
BWI76_RS23000 -1.5 -2.6 nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase compare
BWI76_RS00970 -1.5 -2.0 branched chain amino acid aminotransferase compare
BWI76_RS09970 -1.5 -1.5 porin OmpA compare
BWI76_RS21690 -1.5 -1.6 hypothetical protein compare
BWI76_RS02090 -1.5 -1.8 membrane protein compare
BWI76_RS04305 -1.5 -0.9 molecular chaperone DnaJ compare
BWI76_RS18755 -1.5 -1.0 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS24770 -1.5 -1.6 hypothetical protein compare
BWI76_RS00940 -1.5 -2.6 transcriptional regulator HdfR compare
BWI76_RS13820 -1.5 -1.1 hypothetical protein compare
BWI76_RS25545 -1.4 -2.1 hypothetical protein compare
BWI76_RS23915 -1.4 -1.9 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS15835 -1.4 -1.6 hypothetical protein compare
BWI76_RS13545 -1.4 -1.1 N-acetyltransferase compare
BWI76_RS23325 -1.4 -2.0 hypothetical protein compare
BWI76_RS11440 -1.4 -0.9 hypothetical protein compare
BWI76_RS15765 -1.4 -3.5 hypothetical protein compare
BWI76_RS11035 -1.4 -2.1 putative LysR-family transcriptional regulator compare
BWI76_RS05075 -1.4 -0.9 type II secretion system protein GspG compare
BWI76_RS26065 -1.4 -2.1 phosphoglycolate phosphatase compare
BWI76_RS17290 -1.4 -2.9 formyltetrahydrofolate deformylase compare
BWI76_RS27780 -1.4 -1.9 hypothetical protein compare
BWI76_RS19195 -1.4 -2.9 nickel ABC transporter permease compare
BWI76_RS05885 -1.4 -2.0 anion permease compare
BWI76_RS13420 -1.3 -1.5 ABC transporter permease compare
BWI76_RS02855 -1.3 -1.5 cytochrome B562 compare
BWI76_RS17665 -1.3 -1.9 proteasome-type protease compare
BWI76_RS04270 -1.3 -2.3 transaldolase compare
BWI76_RS11675 -1.3 -1.4 arginine N-succinyltransferase compare
BWI76_RS18385 -1.3 -0.9 hypothetical protein compare
BWI76_RS19670 -1.3 -1.2 S-formylglutathione hydrolase compare
BWI76_RS00725 -1.3 -2.4 periplasmic repressor CpxP compare
BWI76_RS24240 -1.3 -1.3 hypothetical protein compare
BWI76_RS09250 -1.3 -1.6 hypothetical protein compare
BWI76_RS16375 -1.3 -0.9 electron transport complex subunit G compare
BWI76_RS13330 -1.3 -1.2 tellurite resistance methyltransferase TehB compare
BWI76_RS22645 -1.3 -2.5 RNA polymerase sigma factor RpoS compare
BWI76_RS23580 -1.3 -1.1 hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For nitrogen source D-Serine in Klebsiella michiganensis M5al

For nitrogen source D-Serine across organisms