Experiment set6IT019 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-5.6	-8.6	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06355		-4.8	-3.3	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06700		-4.2	-20.4	hypothetical protein
MMP_RS05515		-4.1	-14.7	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS06680		-4.0	-19.1	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06350		-4.0	-10.7	HesA/MoeB/ThiF family protein
MMP_RS03015		-3.8	-18.0	GTP 3' 8-cyclase MoaA
MMP_RS06285		-3.8	-6.0	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS08720		-3.8	-3.6	4Fe-4S binding protein
MMP_RS06685		-3.7	-20.4	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS01755		-3.4	-2.6	DUF2097 domain-containing protein
MMP_RS07635		-3.4	-12.2	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS06345		-3.2	-18.6	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07545		-3.2	-2.5	HTH domain-containing protein
MMP_RS08820		-3.1	-7.7	hypothetical protein
MMP_RS02010		-3.0	-12.2	PHP domain-containing protein
MMP_RS00895		-2.9	-7.7	hypothetical protein
MMP_RS08635		-2.9	-4.1	UbiA family prenyltransferase
MMP_RS08300		-2.9	-2.2	metal-sulfur cluster assembly factor
MMP_RS01985		-2.9	-12.7	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS03315		-2.9	-2.0	ferrous iron transport protein A
MMP_RS04900		-2.8	-21.3	hypothetical protein
MMP_RS07005		-2.8	-1.4	4Fe-4S binding protein
MMP_RS06715		-2.8	-18.8	cache domain-containing protein
MMP_RS00300		-2.7	-1.8	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS07845		-2.7	-5.4	LL-diaminopimelate aminotransferase
MMP_RS00040		-2.7	-5.4	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS08790		-2.7	-4.6	translation initiation factor IF-2 subunit alpha
MMP_RS01020		-2.6	-2.2	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS06295		-2.6	-9.5	methanogenesis marker 14 protein
MMP_RS06720		-2.6	-13.9	response regulator transcription factor
MMP_RS02280		-2.4	-2.0	DUF211 domain-containing protein
MMP_RS00115		-2.4	-16.2	radical SAM protein
MMP_RS07445		-2.4	-6.4	helix-turn-helix domain-containing protein
MMP_RS04775		-2.4	-5.8	adenosylhomocysteinase
MMP_RS03435		-2.4	-3.4	ketol-acid reductoisomerase
MMP_RS04605		-2.3	-8.9	cobalt ECF transporter T component CbiQ
MMP_RS04585		-2.3	-11.9	AIR synthase related protein
MMP_RS01005		-2.3	-2.5	riboflavin synthase
MMP_RS09020		-2.3	-2.8	hypothetical protein
MMP_RS02195		-2.3	-4.1	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS06705		-2.3	-7.6	formate/nitrite transporter family protein
MMP_RS07735		-2.3	-1.8	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS05245		-2.3	-15.9	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS04615		-2.2	-5.1	PDGLE domain-containing protein
MMP_RS08745		-2.2	-8.3	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS02800		-2.2	-9.6	nucleotidyltransferase domain-containing protein
MMP_RS01500		-2.2	-4.0	CBS domain-containing protein
MMP_RS01265		-2.1	-3.4	hypothetical protein
MMP_RS03025		-2.1	-7.3	molybdenum cofactor guanylyltransferase
MMP_RS07525		-2.0	-10.5	4Fe-4S binding protein
MMP_RS04890		-2.0	-1.7	adenylyltransferase/cytidyltransferase family protein
MMP_RS07380		-2.0	-4.0	transcription elongation factor Spt5
MMP_RS01220		-2.0	-12.0	hypothetical protein
MMP_RS06895		-2.0	-2.4	selenocysteine-specific translation elongation factor
MMP_RS01545		-2.0	-2.1	CBS domain-containing protein
MMP_RS07630		-2.0	-2.6	ATP-binding cassette domain-containing protein
MMP_RS02235		-1.9	-12.1	CBS domain-containing protein
MMP_RS08645		-1.9	-9.5	UPF0179 family protein
MMP_RS02355		-1.8	-5.5	30S ribosomal protein S27ae
MMP_RS06625		-1.8	-2.9	DNA primase
MMP_RS06400		-1.8	-2.6	4Fe-4S binding protein
MMP_RS06105		-1.8	-8.1	hydrogenase maturation peptidase HycI
MMP_RS04620		-1.8	-10.8	cobalt transporter CbiM
MMP_RS01980		-1.8	-11.7	trimeric intracellular cation channel family protein
MMP_RS01365		-1.7	-4.2	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS03580		-1.7	-5.7	signal recognition particle-docking protein FtsY
MMP_RS07365		-1.7	-10.9	2-phosphoglycerate kinase
MMP_RS06975		-1.7	-3.7	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS02145		-1.7	-7.8	winged helix-turn-helix transcriptional regulator
MMP_RS02240		-1.7	-5.2	methanogenesis marker 7 protein
MMP_RS00685		-1.7	-4.3	2-phospho-L-lactate guanylyltransferase
MMP_RS03960		-1.7	-1.9	hypothetical protein
MMP_RS00695		-1.6	-1.4	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS08460		-1.6	-3.7	proteasome-activating nucleotidase
MMP_RS07755		-1.6	-2.1	DUF555 domain-containing protein
MMP_RS01610		-1.6	-4.3	hypothetical protein
MMP_RS07390		-1.6	-3.0	cell division protein FtsZ
MMP_RS06475		-1.6	-4.6	FAD-dependent oxidoreductase
MMP_RS01795		-1.6	-2.6	methanogenesis marker 6 protein
MMP_RS07605		-1.6	-4.6	diadenylate cyclase
MMP_RS06270		-1.6	-6.1	TIGR00300 family protein
MMP_RS01325		-1.6	-3.0	dihydroneopterin aldolase family protein
MMP_RS05765		-1.6	-9.0	M42 family metallopeptidase
MMP_RS00295		-1.6	-4.1	gamma carbonic anhydrase family protein
MMP_RS03475		-1.6	-1.1	hypothetical protein
MMP_RS03640		-1.5	-4.8	archaeal proteasome endopeptidase complex subunit beta
MMP_RS02345		-1.5	-4.2	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00620		-1.5	-9.7	4Fe-4S binding protein
MMP_RS08715		-1.5	-3.3	formylmethanofuran dehydrogenase subunit B
MMP_RS04710		-1.5	-2.8	hypothetical protein
MMP_RS04780		-1.5	-3.0	ribonuclease P
MMP_RS01890		-1.5	-6.0	nucleotide sugar dehydrogenase
MMP_RS08210		-1.5	-3.1	phosphatidylglycerophosphatase A
MMP_RS00110		-1.5	-2.9	hypothetical protein
MMP_RS03600		-1.4	-3.6	triose-phosphate isomerase
MMP_RS03035		-1.4	-3.3	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS01700		-1.4	-1.6	dihydroxy-acid dehydratase
MMP_RS07575		-1.4	-3.5	RNA ligase partner protein
MMP_RS04685		-1.4	-4.0	DUF126 domain-containing protein
MMP_RS02165		-1.4	-7.7	tRNA-dihydrouridine synthase
MMP_RS06175		-1.4	-9.7	winged helix-turn-helix transcriptional regulator
MMP_RS01725		-1.4	-5.4	class I SAM-dependent methyltransferase family protein
MMP_RS04870		-1.4	-7.1	TIGR02253 family HAD-type hydrolase
MMP_RS07730		-1.3	-2.3	pyruvate synthase subunit beta
MMP_RS05920		-1.3	-0.9	50S ribosomal protein L37e
MMP_RS06885		-1.3	-3.5	50S ribosome-binding GTPase
MMP_RS02340		-1.3	-3.1	DNA-directed RNA polymerase subunit E''
MMP_RS01380		-1.3	-5.6	PHP domain-containing protein
MMP_RS05555		-1.3	-1.8	DUF4040 domain-containing protein
MMP_RS02190		-1.3	-3.0	sulfopyruvate decarboxylase subunit alpha
MMP_RS01800		-1.3	-3.0	TIGR00303 family protein
MMP_RS06230		-1.3	-3.1	helix-turn-helix domain-containing protein
MMP_RS05875		-1.2	-5.5	hydroxyethylthiazole kinase
MMP_RS08165		-1.2	-2.1	phosphoglycerate dehydrogenase
MMP_RS00305		-1.2	-2.5	phosphoribosyl-ATP diphosphatase
MMP_RS08200		-1.2	-9.8	archaeosine synthase subunit alpha
MMP_RS03080		-1.2	-2.5	universal stress protein
MMP_RS07765		-1.2	-5.9	sodium:alanine symporter family protein
MMP_RS05540		-1.2	-3.6	hypothetical protein
MMP_RS00520		-1.2	-1.9	RNA polymerase Rpb4 family protein
MMP_RS05430		-1.2	-4.8	TIGR00288 family NYN domain-containing protein
MMP_RS07710		-1.2	-5.9	cell division protein FtsZ
MMP_RS03095		-1.2	-6.7	diphthine synthase
MMP_RS03485		-1.1	-5.1	TIGR00267 family protein
MMP_RS01225		-1.1	-4.2	DUF5379 domain-containing protein
MMP_RS06215		-1.1	-2.9	30S ribosomal protein S6e
MMP_RS03205		-1.1	-2.4	peptidyl-tRNA hydrolase Pth2
MMP_RS06200		-1.1	-9.3	M24 family metallopeptidase
MMP_RS07600		-1.1	-4.2	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS07685		-1.1	-4.9	TIGR01212 family radical SAM protein
MMP_RS08320		-1.1	-6.1	molybdopterin molybdotransferase MoeA
MMP_RS03400		-1.0	-2.7	archease
MMP_RS05550		-1.0	-0.9	cation:proton antiporter
MMP_RS08940		-1.0	-1.8	MetS family NSS transporter small subunit
MMP_RS04955		-1.0	-3.7	DNA topoisomerase I
MMP_RS04720		-1.0	-2.6	DedA family protein
MMP_RS01745		-1.0	-3.6	AMP phosphorylase
MMP_RS01180		-1.0	-2.5	XTP/dITP diphosphatase
MMP_RS05510		-1.0	-3.3	Rrf2 family transcriptional regulator
MMP_RS00050		-1.0	-5.2	AarF/UbiB family protein
MMP_RS01600		-1.0	-1.9	50S ribosomal protein L15e
MMP_RS01385		-1.0	-0.8	imidazole glycerol phosphate synthase subunit HisH
MMP_RS03445		-0.9	-1.2	methanogenesis marker 17 protein
MMP_RS06730		-0.9	-1.3	phosphopantothenate/pantothenate synthetase
MMP_RS06120		-0.9	-1.7	UPF0147 family protein
MMP_RS02930		-0.9	-1.8	class I SAM-dependent methyltransferase
MMP_RS01905		-0.9	-7.5	glycosyltransferase
MMP_RS03250		-0.9	-2.5	MJ1244 family protein
MMP_RS03210		-0.9	-7.2	tRNA guanosine(15) transglycosylase TgtA
MMP_RS06865		-0.9	-1.1	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS01575		-0.9	-3.9	aldolase
MMP_RS01840		-0.9	-5.8	TIGR00289 family protein
MMP_RS04090		-0.9	-2.3	hypothetical protein
MMP_RS06340		-0.9	-5.0	phosphoadenosine phosphosulfate reductase family protein
MMP_RS01250		-0.9	-3.3	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS01925		-0.9	-5.4	DUF1616 domain-containing protein
MMP_RS00290		-0.9	-5.0	hypothetical protein
MMP_RS06020		-0.9	-3.6	archaeoflavoprotein AfpA
MMP_RS06930		-0.9	-5.5	MBL fold metallo-hydrolase
MMP_RS06940		-0.8	-2.5	polyprenyl diphosphate synthase
MMP_RS03700		-0.8	-4.4	sodium:proton antiporter
MMP_RS07750		-0.8	-3.1	DUF357 domain-containing protein
MMP_RS08650		-0.8	-2.2	glutamine--fructose-6-phosphate transaminase (isomerizing)
MMP_RS03155		-0.8	-4.8	precorrin-6A reductase
MMP_RS06855		-0.8	-5.4	hypothetical protein
MMP_RS02170		-0.8	-4.6	CBS domain-containing protein
MMP_RS03590		-0.8	-3.0	METTL5 family protein
MMP_RS05345		-0.8	-4.0	hypothetical protein
MMP_RS07200		-0.8	-3.5	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS07425		-0.8	-4.7	GTP-binding protein
MMP_RS08445		-0.8	-3.7	DUF2099 family protein
MMP_RS05845		-0.7	-1.5	tRNA-intron lyase
MMP_RS00915		-0.7	-3.9	DUF116 domain-containing protein
MMP_RS02245		-0.7	-3.2	hypothetical protein
MMP_RS03470		-0.7	-4.8	phosphoadenosine phosphosulfate reductase family protein
MMP_RS00515		-0.7	-1.0	DUF655 domain-containing protein
MMP_RS06130		-0.7	-1.9	peptidylprolyl isomerase
MMP_RS01875		-0.7	-4.7	N-acetyltransferase
MMP_RS05545		-0.7	-3.9	pyridoxal phosphate-dependent aminotransferase
MMP_RS05800		-0.7	-5.3	B12-binding domain-containing radical SAM protein
MMP_RS00810		-0.7	-4.2	topoisomerase DNA-binding C4 zinc finger domain-containing protein
MMP_RS01885		-0.7	-4.6	Gfo/Idh/MocA family oxidoreductase
MMP_RS06925		-0.7	-2.0	ribonuclease VapC4
MMP_RS01900		-0.7	-5.5	hypothetical protein
MMP_RS05440		-0.7	-3.3	winged helix-turn-helix transcriptional regulator
MMP_RS00720		-0.7	-4.0	metal-dependent hydrolase
MMP_RS05500		-0.7	-4.9	2-isopropylmalate synthase
MMP_RS08785		-0.7	-1.0	RNA-protein complex protein Nop10
MMP_RS06110		-0.7	-2.6	ATP-dependent protease LonB
MMP_RS05315		-0.7	-2.1	hypothetical protein
MMP_RS06980		-0.7	-3.9	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS06315		-0.7	-0.8	cobalt-precorrin-7 (C(5))-methyltransferase
MMP_RS07705		-0.7	-4.8	transcriptional regulator
MMP_RS03300		-0.6	-0.9	TOBE domain-containing protein
MMP_RS07580		-0.6	-2.0	DUF356 domain-containing protein
MMP_RS02135		-0.6	-2.2	DUF5612 domain-containing protein
MMP_RS02885		-0.6	-5.1	molybdopterin biosynthesis protein
MMP_RS07090		-0.6	-3.1	tRNA (adenine-N1)-methyltransferase
MMP_RS00555		-0.6	-2.7	MFS transporter

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments