Experiment set6IT019 for Klebsiella michiganensis M5al

Compare to:

L-Tryptophan nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04160 -9.1 -6.3 phosphoserine phosphatase compare
BWI76_RS18950 -8.3 -5.6 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS01210 -7.9 -4.8 tyrosine recombinase XerC compare
BWI76_RS05835 -7.1 -4.9 gamma-glutamyl-phosphate reductase compare
BWI76_RS04465 -6.8 -6.6 carbamoyl-phosphate synthase small subunit compare
BWI76_RS02995 -5.9 -8.3 aspartate carbamoyltransferase compare
BWI76_RS05015 -5.9 -4.0 transcriptional regulator compare
BWI76_RS27385 -5.9 -8.0 orotate phosphoribosyltransferase compare
BWI76_RS04470 -5.8 -10.5 carbamoyl phosphate synthase large subunit compare
BWI76_RS20895 -5.8 -6.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS18925 -5.7 -5.5 histidinol dehydrogenase compare
BWI76_RS23920 -5.6 -5.0 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00850 -5.4 -9.3 acetylglutamate kinase compare
BWI76_RS10990 -5.3 -2.8 dihydroorotase compare
BWI76_RS18935 -5.3 -5.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS00385 -5.3 -9.1 nitrogen assimilation regulatory protein compare
BWI76_RS04255 -5.3 -9.4 threonine synthase compare
BWI76_RS11965 -5.2 -4.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS23360 -5.2 -5.1 diaminopimelate decarboxylase compare
BWI76_RS01615 -5.2 -11.7 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS09645 -5.2 -1.8 thioredoxin-disulfide reductase compare
BWI76_RS04250 -5.1 -6.5 homoserine kinase compare
BWI76_RS18920 -5.1 -4.2 ATP phosphoribosyltransferase compare
BWI76_RS07070 -5.1 -7.6 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS18940 -5.0 -6.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS18930 -5.0 -3.9 histidinol-phosphate transaminase compare
BWI76_RS00965 -5.0 -1.7 acetolactate synthase 2 small subunit compare
BWI76_RS04645 -4.9 -6.2 3-dehydroquinase compare
BWI76_RS20355 -4.9 -3.0 colicin V production protein compare
BWI76_RS09760 -4.9 -4.2 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS05840 -4.9 -6.6 glutamate 5-kinase compare
BWI76_RS00400 -4.9 -2.9 glutamine synthetase compare
BWI76_RS09910 -4.7 -15.2 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS06530 -4.6 -7.0 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS00390 -4.6 -8.9 two-component system sensor histidine kinase NtrB compare
BWI76_RS00855 -4.5 -7.6 argininosuccinate lyase compare
BWI76_RS20965 -4.5 -3.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS03010 -4.5 -6.5 ornithine carbamoyltransferase compare
BWI76_RS00990 -4.4 -9.3 ketol-acid reductoisomerase compare
BWI76_RS00845 -4.3 -6.1 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS05200 -4.3 -2.9 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS20350 -4.2 -4.6 amidophosphoribosyltransferase compare
BWI76_RS25115 -4.2 -8.6 argininosuccinate synthase compare
BWI76_RS21265 -4.2 -11.2 phosphoribosylformylglycinamidine synthase compare
BWI76_RS26085 -4.2 -3.2 3-dehydroquinate synthase compare
BWI76_RS23240 -4.1 -4.0 exonuclease V subunit gamma compare
BWI76_RS09755 -4.0 -8.2 phosphoserine transaminase compare
BWI76_RS23230 -4.0 -3.9 exodeoxyribonuclease V subunit beta compare
BWI76_RS23220 -4.0 -6.6 amino-acid N-acetyltransferase compare
BWI76_RS22805 -3.9 -8.0 GTP diphosphokinase compare
BWI76_RS15825 -3.8 -2.3 hypothetical protein compare
BWI76_RS22755 -3.7 -7.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS21465 -3.7 -3.8 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS00345 -3.7 -5.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS04240 -3.6 -2.8 thr operon leader peptide compare
BWI76_RS04245 -3.4 -12.3 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS08385 -3.4 -4.1 citrate (Si)-synthase compare
BWI76_RS01610 -3.4 -7.9 phosphoribosylamine--glycine ligase compare
BWI76_RS01925 -3.4 -8.5 aromatic amino acid aminotransferase compare
BWI76_RS00975 -3.2 -7.8 dihydroxy-acid dehydratase compare
BWI76_RS08180 -3.2 -6.0 asparagine synthase B compare
BWI76_RS27430 -3.1 -1.5 (p)ppGpp synthetase compare
BWI76_RS27440 -3.0 -4.8 DNA helicase RecG compare
BWI76_RS04675 -3.0 -8.4 3-isopropylmalate dehydrogenase compare
BWI76_RS05990 -3.0 -7.8 branched-chain amino acid ABC transporter permease compare
BWI76_RS16955 -3.0 -1.5 hypothetical protein compare
BWI76_RS00805 -3.0 -3.0 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS01385 -2.9 -4.4 potassium transporter compare
BWI76_RS05980 -2.9 -5.4 ABC transporter ATP-binding protein compare
BWI76_RS20435 -2.9 -1.3 chorismate synthase compare
BWI76_RS23480 -2.9 -12.9 EAL domain-containing protein compare
BWI76_RS06800 -2.9 -1.7 DUF2496 domain-containing protein compare
BWI76_RS09660 -2.8 -2.9 DNA translocase FtsK compare
BWI76_RS21370 -2.8 -2.6 ATP-dependent RNA helicase SrmB compare
BWI76_RS04665 -2.8 -15.4 3-isopropylmalate dehydratase small subunit compare
BWI76_RS04670 -2.8 -8.5 3-isopropylmalate dehydratase large subunit compare
BWI76_RS00835 -2.8 -12.9 phosphoenolpyruvate carboxylase compare
BWI76_RS07065 -2.8 -5.8 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS09970 -2.8 -4.8 porin OmpA compare
BWI76_RS01655 -2.8 -6.4 homoserine O-succinyltransferase compare
BWI76_RS04685 -2.7 -8.3 putative leucine operon leader peptide compare
BWI76_RS22690 -2.7 -2.3 adenylyl-sulfate kinase compare
BWI76_RS25960 -2.6 -4.3 NUDIX hydrolase compare
BWI76_RS12090 -2.6 -2.0 HNH endonuclease compare
BWI76_RS05985 -2.6 -4.6 branched-chain amino acid ABC transporter permease compare
BWI76_RS00785 -2.6 -6.3 cystathionine gamma-synthase compare
BWI76_RS00980 -2.6 -9.8 PLP-dependent threonine dehydratase compare
BWI76_RS22765 -2.6 -8.5 sulfite reductase subunit alpha compare
BWI76_RS26570 -2.6 -3.3 anion permease compare
BWI76_RS06765 -2.6 -4.3 transcriptional regulator compare
BWI76_RS03665 -2.5 -2.3 ABC transporter ATP-binding protein compare
BWI76_RS02530 -2.5 -3.1 tRNA dimethylallyltransferase compare
BWI76_RS05975 -2.5 -4.1 ABC transporter ATP-binding protein compare
BWI76_RS18715 -2.5 -8.2 hypothetical protein compare
BWI76_RS17345 -2.5 -8.6 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS18630 -2.5 -5.5 nitrogen assimilation transcriptional regulator compare
BWI76_RS27390 -2.5 -3.2 ribonuclease PH compare
BWI76_RS16235 -2.4 -3.3 membrane protein compare
BWI76_RS25065 -2.4 -3.0 polyribonucleotide nucleotidyltransferase compare
BWI76_RS26830 -2.4 -6.0 endoglucanase compare
BWI76_RS14415 -2.4 -2.7 transcriptional regulator, TetR family protein compare
BWI76_RS08520 -2.4 -2.2 colicin transporter TolQ compare
BWI76_RS22485 -2.4 -4.1 hypothetical protein compare
BWI76_RS08530 -2.3 -2.3 protein TolA compare
BWI76_RS26055 -2.3 -9.3 siroheme synthase compare
BWI76_RS02410 -2.3 -2.2 EF-P beta-lysylation protein EpmB compare
BWI76_RS21565 -2.3 -1.6 outer membrane protein assembly factor BamE compare
BWI76_RS05995 -2.3 -6.1 branched-chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS25645 -2.3 -7.0 shikimate dehydrogenase compare
BWI76_RS06525 -2.2 -4.1 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS22760 -2.2 -4.4 sulfite reductase subunit beta compare
BWI76_RS25280 -2.1 -2.1 RNase adaptor protein RapZ compare
BWI76_RS14320 -2.1 -2.9 hypothetical protein compare
BWI76_RS04680 -2.1 -7.5 2-isopropylmalate synthase compare
BWI76_RS24285 -2.0 -6.0 cystathionine beta-lyase compare
BWI76_RS23265 -2.0 -4.4 hypothetical protein compare
BWI76_RS18710 -2.0 -10.1 GGDEF-domain containing protein compare
BWI76_RS05915 -1.9 -3.6 helix-turn-helix transcriptional regulator compare
BWI76_RS20650 -1.9 -1.9 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS21475 -1.9 -4.8 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS16965 -1.8 -5.1 murein lipoprotein compare
BWI76_RS06000 -1.8 -9.8 ethanolamine ammonia-lyase small subunit compare
BWI76_RS06770 -1.8 -7.3 Hha toxicity attenuator compare
BWI76_RS21070 -1.7 -1.8 outer membrane protein assembly factor BamB compare
BWI76_RS15835 -1.7 -1.0 hypothetical protein compare
BWI76_RS06535 -1.7 -4.1 endopeptidase La compare
BWI76_RS04270 -1.7 -3.4 transaldolase compare
BWI76_RS25505 -1.7 -6.0 RNase E specificity factor CsrD compare
BWI76_RS17530 -1.7 -3.3 hypothetical protein compare
BWI76_RS04715 -1.6 -2.0 division/cell wall cluster transcriptional repressor MraZ compare
BWI76_RS15215 -1.6 -1.4 N-acetyltransferase compare
BWI76_RS03540 -1.6 -3.8 tryptophanase leader peptide compare
BWI76_RS13755 -1.6 -1.9 hypothetical protein compare
BWI76_RS15975 -1.6 -1.4 hypothetical protein compare
BWI76_RS17525 -1.6 -1.3 XshC-Cox1-family protein compare
BWI76_RS27425 -1.5 -1.8 DNA-directed RNA polymerase subunit omega compare
BWI76_RS16895 -1.5 -1.7 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS12790 -1.5 -1.2 lactate dehydrogenase compare
BWI76_RS17735 -1.5 -2.8 D-amino acid dehydrogenase small subunit compare
BWI76_RS24955 -1.5 -2.2 hypothetical protein compare
BWI76_RS05120 -1.5 -7.3 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS26775 -1.5 -4.4 endo-1,4-D-glucanase compare
BWI76_RS19845 -1.5 -3.8 phosphatase compare
BWI76_RS06005 -1.5 -5.3 ethanolamine ammonia lyase large subunit compare
BWI76_RS02725 -1.5 -1.2 HxlR family transcriptional regulator compare
BWI76_RS13820 -1.4 -2.2 hypothetical protein compare
BWI76_RS13420 -1.4 -1.5 ABC transporter permease compare
BWI76_RS18955 -1.4 -2.4 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS26075 -1.4 -2.7 DNA adenine methylase compare
BWI76_RS26440 -1.4 -1.5 hypothetical protein compare
BWI76_RS08925 -1.4 -4.2 DNA-binding protein YbiB compare
BWI76_RS25070 -1.4 -1.3 hypothetical protein compare
BWI76_RS26065 -1.4 -1.6 phosphoglycolate phosphatase compare
BWI76_RS16515 -1.4 -1.6 LysR family transcriptional regulator compare
BWI76_RS19010 -1.4 -2.6 polysaccharide pyruvyl transferase yvff compare
BWI76_RS08535 -1.3 -1.3 translocation protein TolB compare
BWI76_RS12590 -1.3 -1.7 helix-turn-helix-type transcriptional regulator compare
BWI76_RS13325 -1.3 -3.0 dicarboxylate transporter/tellurite-resistance protein TehA compare
BWI76_RS24485 -1.3 -1.9 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS12745 -1.3 -2.4 putative prophage membrane protein compare
BWI76_RS18770 -1.3 -1.1 DNA gyrase inhibitor compare
BWI76_RS26390 -1.3 -3.0 cell division protein FtsX compare
BWI76_RS25335 -1.3 -2.5 stringent starvation protein A compare
BWI76_RS06465 -1.3 -1.7 IclR family transcriptional regulator compare
BWI76_RS01115 -1.2 -3.0 dTDP-4-amino-4,6-dideoxygalactose transaminase compare
BWI76_RS13595 -1.2 -2.7 transcriptional regulator compare
BWI76_RS25910 -1.2 -4.5 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS15810 -1.2 -3.5 hypothetical protein compare
BWI76_RS23020 -1.2 -1.0 cobalamin biosynthesis protein CbiQ compare
BWI76_RS17980 -1.2 -2.0 RNA chaperone ProQ compare
BWI76_RS26175 -1.2 -2.9 DeoR/GlpR family transcriptional regulator compare
BWI76_RS09255 -1.1 -1.7 hypothetical protein compare
BWI76_RS03535 -1.1 -7.9 Tryptophanase (EC 4.1.99.1) (from data) compare
BWI76_RS26045 -1.1 -1.8 nitrite reductase small subunit compare
BWI76_RS11125 -1.1 -1.4 metal-dependent hydrolase compare
BWI76_RS08525 -1.1 -1.0 colicin transporter compare
BWI76_RS14050 -1.1 -1.8 AP endonuclease, family 2 compare
BWI76_RS23760 -1.1 -1.5 tRNA-Gly compare
BWI76_RS24025 -1.1 -4.6 agmatinase compare
BWI76_RS21480 -1.1 -4.0 phospho-2-dehydro-3-deoxyheptonate aldolase compare
BWI76_RS20640 -1.1 -4.0 cysteine synthase A compare
BWI76_RS06010 -1.1 -4.9 ethanolamine permease compare
BWI76_RS01060 -1.1 -4.4 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase compare
BWI76_RS08705 -1.1 -2.3 putative LuxR family regulatory protein compare
BWI76_RS17720 -1.1 -1.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS24120 -1.1 -2.8 YggW family oxidoreductase compare
BWI76_RS02550 -1.0 -3.0 protease modulator HflC compare
BWI76_RS01350 -1.0 -0.9 NAD(P)H-flavin reductase compare
BWI76_RS11700 -1.0 -1.2 hypothetical protein compare
BWI76_RS26460 -1.0 -3.0 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS14390 -1.0 -1.1 hypothetical protein compare
BWI76_RS09960 -1.0 -1.6 Lon protease compare
BWI76_RS06605 -1.0 -4.2 ammonium transporter compare
BWI76_RS01125 -1.0 -2.5 4-alpha-L-fucosyltransferase compare
BWI76_RS14950 -1.0 -3.6 glycosylasparaginase compare
BWI76_RS11235 -1.0 -0.9 hypothetical protein compare
BWI76_RS16935 -1.0 -1.2 shikimate dehydrogenase compare
BWI76_RS18605 -1.0 -0.9 oxidoreductase molybdopterin-binding protein compare
BWI76_RS05235 -1.0 -0.9 hypothetical protein compare
BWI76_RS21870 -1.0 -2.7 hypothetical protein compare


Specific Phenotypes

For 14 genes in this experiment

For nitrogen source L-Tryptophan in Klebsiella michiganensis M5al

For nitrogen source L-Tryptophan across organisms