Experiment set6IT019 for Klebsiella michiganensis M5al

Compare to:

L-Tryptophan nitrogen source

200 most detrimental genes:

  gene name fitness t score description  
BWI76_RS01585 +1.6 5.8 transcriptional regulator compare
BWI76_RS15920 +1.6 2.9 hypothetical protein compare
BWI76_RS20910 +1.6 8.7 glycine cleavage system transcriptional repressor compare
BWI76_RS17740 +1.5 11.1 SpoVR family protein compare
BWI76_RS08825 +1.5 4.0 cyclic pyranopterin monophosphate synthase MoaC compare
BWI76_RS14935 +1.4 2.3 NIPSNAP family containing protein compare
BWI76_RS22090 +1.4 2.7 transcriptional regulator compare
BWI76_RS11480 +1.4 8.5 hypothetical protein compare
BWI76_RS04275 +1.3 6.2 molybdopterin adenylyltransferase compare
BWI76_RS11485 +1.3 5.2 serine protein kinase PrkA compare
BWI76_RS15660 +1.2 1.5 hypothetical protein compare
BWI76_RS20730 +1.2 2.7 hypothetical protein compare
BWI76_RS08815 +1.2 4.9 cyclic pyranopterin phosphate synthase compare
BWI76_RS09615 +1.1 1.5 ATP-dependent Clp protease ATP-binding subunit ClpA compare
BWI76_RS06125 +1.1 5.4 D-alanine--D-alanine ligase A compare
BWI76_RS17945 +1.1 1.5 hypothetical protein compare
BWI76_RS08750 +1.1 1.8 kinase inhibitor compare
BWI76_RS11820 +1.1 1.5 short-chain dehydrogenase/reductase SDR compare
BWI76_RS11845 +1.0 1.3 tryptophan synthase subunit beta compare
BWI76_RS25220 +1.0 2.9 outer membrane lipid asymmetry maintenance protein MlaD compare
BWI76_RS17330 +1.0 3.0 nitrate reductase subunit beta compare
BWI76_RS09655 +1.0 6.3 leucine-responsive regulatory protein compare
BWI76_RS02570 +1.0 4.6 transcriptional regulator compare
BWI76_RS13685 +1.0 3.0 IclR family transcriptional regulator compare
BWI76_RS05315 +1.0 2.0 Rho-binding antiterminator compare
BWI76_RS24575 +1.0 1.6 hypothetical protein compare
BWI76_RS21675 +1.0 1.1 hypothetical protein compare
BWI76_RS17045 +1.0 2.1 hypothetical protein compare
BWI76_RS08835 +1.0 2.6 molybdopterin guanine dinucleotide biosynthesis protein MoaE compare
BWI76_RS20375 +1.0 1.0 membrane protein compare
BWI76_RS09650 +1.0 6.0 hypothetical protein compare
BWI76_RS09625 +1.0 1.6 hypothetical protein compare
BWI76_RS15130 +0.9 2.9 hypothetical protein compare
BWI76_RS00715 +0.9 2.6 two-component sensor histidine kinase compare
BWI76_RS04955 +0.9 0.8 hypoxanthine phosphoribosyltransferase compare
BWI76_RS12485 +0.9 4.4 TyrR family transcriptional regulator compare
BWI76_RS11635 +0.9 1.5 ABC transporter compare
BWI76_RS05555 +0.9 2.6 Crl family RNA polymerase assembly factor compare
BWI76_RS10745 +0.9 1.3 hypothetical protein compare
BWI76_RS13320 +0.9 3.2 putative LpxA-like enzyme compare
BWI76_RS07510 +0.9 2.5 hypothetical protein compare
BWI76_RS12235 +0.9 1.6 hypothetical protein compare
BWI76_RS20970 +0.9 1.7 phosphoribosylglycinamide formyltransferase compare
BWI76_RS07865 +0.9 1.6 methylthioribulose 1-phosphate dehydratase compare
BWI76_RS18060 +0.9 2.2 hypothetical protein compare
BWI76_RS09085 +0.9 6.5 molybdopterin molybdenumtransferase MoeA compare
BWI76_RS00330 +0.9 4.1 molybdenum cofactor guanylyltransferase compare
BWI76_RS09635 +0.9 1.4 amino acid ABC transporter ATP-binding protein compare
BWI76_RS12860 +0.9 2.6 hypothetical protein compare
BWI76_RS12420 +0.8 1.2 peptide ABC transporter substrate-binding protein SapA compare
BWI76_RS21165 +0.8 1.8 Fe-S cluster assembly transcriptional regulator IscR compare
BWI76_RS17155 +0.8 1.6 hypothetical protein compare
BWI76_RS16275 +0.8 2.1 fumarate hydratase FumA compare
BWI76_RS09515 +0.8 2.0 arginine ABC transporter substrate-binding protein compare
BWI76_RS18335 +0.8 4.4 DNA-binding response regulator compare
BWI76_RS07705 +0.8 1.6 enterochelin esterase compare
BWI76_RS24765 +0.8 1.8 membrane protein compare
BWI76_RS16230 +0.8 2.0 dihydromonapterin reductase compare
BWI76_RS16140 +0.8 2.7 3-oxoadipate CoA-transferase compare
BWI76_RS09490 +0.8 2.1 DNA-binding response regulator compare
BWI76_RS16150 +0.8 1.1 IclR family transcriptional regulator compare
BWI76_RS21075 +0.8 1.1 membrane protein compare
BWI76_RS20230 +0.8 1.5 hypothetical protein compare
BWI76_RS22815 +0.8 5.4 hybrid sensor histidine kinase/response regulator compare
BWI76_RS25425 +0.8 1.9 arginine repressor compare
BWI76_RS21810 +0.8 0.7 universal stress protein compare
BWI76_RS15280 +0.7 1.9 sugar transporter compare
BWI76_RS04700 +0.7 3.7 acetolactate synthase small subunit compare
BWI76_RS09610 +0.7 2.4 ATP-dependent Clp protease adaptor ClpS compare
BWI76_RS17420 +0.7 2.8 hypothetical protein compare
BWI76_RS04175 +0.7 2.4 energy-dependent translational throttle protein EttA compare
BWI76_RS10510 +0.7 1.6 OHCU decarboxylase compare
BWI76_RS15260 +0.7 1.3 hypothetical protein compare
BWI76_RS26205 +0.7 3.2 glucose-1-phosphate adenylyltransferase compare
BWI76_RS04090 +0.7 2.4 ribosomal-protein-alanine N-acetyltransferase RimI compare
BWI76_RS07860 +0.7 1.2 cytosine permease compare
BWI76_RS16425 +0.7 2.2 hypothetical protein compare
BWI76_RS23895 +0.7 0.9 Xaa-Pro aminopeptidase compare
BWI76_RS23080 +0.7 2.8 precorrin-8X methylmutase compare
BWI76_RS05520 +0.7 2.3 hypothetical protein compare
BWI76_RS16170 +0.7 1.9 amidohydrolase compare
BWI76_RS11780 +0.7 0.9 2-deoxyglucose-6-phosphatase compare
BWI76_RS26245 +0.7 2.4 transcriptional regulator compare
BWI76_RS19835 +0.7 2.3 nucleoid-associated protein YejK compare
BWI76_RS05450 +0.7 0.7 ribonuclease HI compare
BWI76_RS27605 +0.7 1.2 hypothetical protein compare
BWI76_RS21490 +0.7 4.6 GGDEF domain-containing protein compare
BWI76_RS11610 +0.7 1.2 glutamate dehydrogenase compare
BWI76_RS21245 +0.7 2.3 nitrogen regulatory protein P-II compare
BWI76_RS22960 +0.7 2.0 YgdI/YgdR family lipoprotein compare
BWI76_RS15915 +0.7 2.8 YnfC family lipoprotein compare
BWI76_RS04560 +0.7 1.5 holo-ACP synthase CitX compare
BWI76_RS08650 +0.7 1.7 molybdate ABC transporter permease compare
BWI76_RS07475 +0.7 0.9 DNA-binding transcriptional regulator RamA compare
BWI76_RS08315 +0.7 2.1 K+-transporting ATPase subunit B compare
BWI76_RS05070 +0.7 0.7 type II secretion system protein GspH compare
BWI76_RS26015 +0.7 1.6 DUF2559 domain-containing protein compare
BWI76_RS14245 +0.7 1.2 carboxymuconolactone decarboxylase family protein compare
BWI76_RS15135 +0.7 2.5 hypothetical protein compare
BWI76_RS14840 +0.6 2.0 hypothetical protein compare
BWI76_RS15345 +0.6 1.7 5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase compare
BWI76_RS04855 +0.6 3.4 regulatory protein AmpE compare
BWI76_RS05655 +0.6 2.3 hypothetical protein compare
BWI76_RS22645 +0.6 3.2 RNA polymerase sigma factor RpoS compare
BWI76_RS25870 +0.6 1.4 elongation factor Tu compare
BWI76_RS15950 +0.6 0.8 dethiobiotin synthase compare
BWI76_RS05800 +0.6 1.5 phage transcriptional activator, Ogr/delta compare
BWI76_RS11840 +0.6 1.1 tryptophan synthase subunit alpha compare
BWI76_RS13930 +0.6 1.5 putative LysR-family transcriptional regulator compare
BWI76_RS19245 +0.6 1.6 dimethylargininase compare
BWI76_RS11990 +0.6 3.7 exoribonuclease II compare
BWI76_RS11035 +0.6 1.6 putative LysR-family transcriptional regulator compare
BWI76_RS15970 +0.6 2.1 carboxypeptidase M32 compare
BWI76_RS14290 +0.6 2.9 AAA family ATPase compare
BWI76_RS00180 +0.6 1.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS17180 +0.6 2.0 hypothetical protein compare
BWI76_RS23050 +0.6 1.5 cobalt-precorrin-3B C(17)-methyltransferase compare
BWI76_RS12460 +0.6 1.7 envelope stress response membrane protein PspC compare
BWI76_RS13775 +0.6 1.6 putative FMN-dependent luciferase-like monooxygenase compare
BWI76_RS12815 +0.6 2.1 transcriptional regulator FeaR compare
BWI76_RS10700 +0.6 1.5 XRE family transcriptional regulator compare
BWI76_RS10635 +0.6 1.6 GGDEF domain-containing protein compare
BWI76_RS19220 +0.6 1.9 hypothetical protein compare
BWI76_RS08645 +0.6 1.5 molybdate ABC transporter substrate-binding protein compare
BWI76_RS15205 +0.6 1.5 succinate-semialdehyde dehydrogenase compare
BWI76_RS19575 +0.6 1.0 maleylacetoacetate isomerase compare
BWI76_RS21460 +0.6 0.9 translation inhibitor protein RaiA compare
BWI76_RS01030 +0.6 3.0 cytosine/purine, uracil, thiamine, allantoin permease family protein compare
BWI76_RS20845 +0.6 1.5 GDP-mannose pyrophosphatase NudK compare
BWI76_RS21685 +0.6 1.0 hypothetical protein compare
BWI76_RS15940 +0.6 0.8 DMSO reductase maturation protein DsmD compare
BWI76_RS13545 +0.6 1.1 N-acetyltransferase compare
BWI76_RS18235 +0.6 2.7 trehalose-phosphatase compare
BWI76_RS17375 +0.6 0.9 nitrate ABC transporter, permease protein compare
BWI76_RS03520 +0.6 5.0 diguanylate cyclase compare
BWI76_RS15980 +0.6 1.4 lysine transporter LysE compare
BWI76_RS12340 +0.6 1.5 molecular chaperone Tir compare
BWI76_RS18455 +0.6 0.8 tRNA-Ser compare
BWI76_RS08770 +0.6 2.9 malonyl-ACP O-methyltransferase BioC compare
BWI76_RS16360 +0.6 0.9 electron transport complex subunit RsxB compare
BWI76_RS25285 +0.6 0.8 HPr family phosphocarrier protein compare
BWI76_RS09520 +0.6 1.0 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS04605 +0.6 0.9 thiamine ABC transporter ATP-binding protein compare
BWI76_RS18885 +0.6 1.0 nitrogen fixation regulatory protein compare
BWI76_RS24925 +0.6 1.1 DnaA initiator-associating protein DiaA compare
BWI76_RS18035 +0.6 2.4 fimbrial chaperone compare
BWI76_RS11460 +0.6 1.7 DUF441 family protein compare
BWI76_RS21450 +0.6 0.9 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS02970 +0.6 3.9 trehalose operon repressor compare
BWI76_RS26835 +0.6 2.5 hypothetical protein compare
BWI76_RS22210 +0.6 2.4 murein transglycosylase B compare
BWI76_RS15445 +0.5 1.3 hypothetical protein compare
BWI76_RS07905 +0.5 2.8 trimethylamine-N-oxide reductase (cytochrome c) compare
BWI76_RS21570 +0.5 1.2 RnfH family protein compare
BWI76_RS21485 +0.5 3.3 DUF4154 domain-containing protein compare
BWI76_RS22435 +0.5 1.8 iron ABC transporter permease AfeC compare
BWI76_RS15190 +0.5 2.0 GGDEF domain-containing protein compare
BWI76_RS15450 +0.5 1.6 hypothetical protein compare
BWI76_RS11255 +0.5 0.9 putrescine/spermidine ABC transporter ATP-binding protein compare
BWI76_RS02180 +0.5 0.8 hypothetical protein compare
BWI76_RS23915 +0.5 1.0 5-formyltetrahydrofolate cyclo-ligase compare
BWI76_RS09460 +0.5 2.7 spermidine/putrescine ABC transporter substrate-binding protein PotF compare
BWI76_RS21445 +0.5 2.2 hypothetical protein compare
BWI76_RS17765 +0.5 1.6 hypothetical protein compare
BWI76_RS06060 +0.5 1.0 DNA-binding response regulator compare
BWI76_RS08500 +0.5 1.5 cytochrome d ubiquinol oxidase subunit 2 compare
BWI76_RS00285 +0.5 1.2 D-ribose ABC transporter substrate-binding protein compare
BWI76_RS21495 +0.5 2.1 outer membrane lipoprotein compare
BWI76_RS19100 +0.5 2.4 putative acid phosphatase compare
BWI76_RS02685 +0.5 1.9 opacity-associated protein compare
BWI76_RS03045 +0.5 0.7 hypothetical protein compare
BWI76_RS26635 +0.5 1.7 hypothetical protein compare
BWI76_RS10015 +0.5 2.1 putative outer membrane efflux protein compare
BWI76_RS05810 +0.5 0.7 hypothetical protein compare
BWI76_RS19750 +0.5 1.1 elongation factor P-like protein YeiP compare
BWI76_RS20410 +0.5 2.4 bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC compare
BWI76_RS20295 +0.5 2.2 dihydroneopterin triphosphate 2'-epimerase compare
BWI76_RS13780 +0.5 2.3 ABC transporter ATP-binding protein compare
BWI76_RS26930 +0.5 1.6 biotin sulfoxide reductase compare
BWI76_RS01245 +0.5 2.3 DNA helicase RecQ compare
BWI76_RS00710 +0.5 1.1 6-N-hydroxylaminopurine resistance protein compare
BWI76_RS24795 +0.5 1.4 hypothetical protein compare
BWI76_RS11515 +0.5 0.8 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS12620 +0.5 2.0 2-nitropropane dioxygenase compare
BWI76_RS11170 +0.5 0.7 hypothetical protein compare
BWI76_RS03310 +0.5 1.1 AraC family transcriptional regulator compare
BWI76_RS03140 +0.5 2.1 alcohol dehydrogenase compare
BWI76_RS07165 +0.5 1.5 hypothetical protein compare
BWI76_RS00720 +0.5 1.1 DNA-binding response regulator compare
BWI76_RS16975 +0.5 1.3 cysteine desufuration protein SufE compare
BWI76_RS15095 +0.5 1.8 isochorismatase compare
BWI76_RS09860 +0.5 1.0 hypothetical protein compare
BWI76_RS16810 +0.5 2.2 RpiR family transcriptional regulator compare
BWI76_RS10870 +0.5 1.9 nicotinamidase compare
BWI76_RS09640 +0.5 1.9 cysteine/glutathione ABC transporter permease/ATP-binding protein CydD compare
BWI76_RS02190 +0.5 1.5 ribose 1,5-bisphosphokinase compare
BWI76_RS16505 +0.5 1.3 MFS transporter compare
BWI76_RS02625 +0.5 2.0 PTS ascorbate transporter subunit IIB compare
BWI76_RS13150 +0.5 1.3 carnitine operon protein CaiE compare
BWI76_RS15035 +0.5 0.7 metal ABC transporter permease compare


Specific Phenotypes

For 14 genes in this experiment

For nitrogen source L-Tryptophan in Klebsiella michiganensis M5al

For nitrogen source L-Tryptophan across organisms