Experiment set6IT019 for Paraburkholderia bryophila 376MFSha3.1

Compare to:

3-Hydroxypropionate carbon source

200 most important genes:

  gene name fitness t score description  
H281DRAFT_02926 -7.3 -11.9 diguanylate cyclase/phosphodiesterase compare
H281DRAFT_05801 -5.7 -6.8 5,10-methylenetetrahydrofolate reductase (NAD(P)) compare
H281DRAFT_06067 -5.6 -14.1 tryptophan synthase, beta chain compare
H281DRAFT_04610 -5.5 -20.3 Fe-S oxidoreductase compare
H281DRAFT_06008 -5.3 -9.9 RNA polymerase, sigma 70 subunit, RpoD compare
H281DRAFT_00471 -5.1 -8.1 transcriptional regulator, IclR family compare
H281DRAFT_03926 -5.0 -11.8 phosphoserine aminotransferase apoenzyme compare
H281DRAFT_02214 -5.0 -19.0 homoserine O-acetyltransferase compare
H281DRAFT_00909 -4.9 -6.5 phosphoribosylformylglycinamidine synthase compare
H281DRAFT_05620 -4.8 -18.8 glutamate synthase (NADH) large subunit compare
H281DRAFT_02000 -4.7 -7.6 glycerol-3-phosphate dehydrogenase (NAD(P)+) compare
H281DRAFT_06072 -4.6 -7.1 3-isopropylmalate dehydrogenase compare
H281DRAFT_05618 -4.6 -9.2 outer membrane protein compare
H281DRAFT_04831 -4.5 -4.4 hypothetical protein compare
H281DRAFT_05714 -4.5 -4.7 anthranilate synthase, component II compare
H281DRAFT_02372 -4.4 -4.4 transcriptional regulator, LysR family compare
H281DRAFT_05715 -4.4 -18.6 anthranilate synthase, component I compare
H281DRAFT_01798 -4.4 -4.1 Transmembrane transcriptional regulator (anti-sigma factor RsiW) compare
H281DRAFT_05713 -4.3 -8.9 anthranilate phosphoribosyltransferase compare
H281DRAFT_04710 -4.2 -4.1 phosphoribosylformylglycinamidine cyclo-ligase compare
H281DRAFT_02004 -4.2 -6.5 phosphoglycerate mutase compare
H281DRAFT_04119 -4.2 -7.7 ornithine carbamoyltransferase compare
H281DRAFT_06059 -4.2 -9.7 O-succinylhomoserine sulfhydrylase compare
H281DRAFT_06068 -4.2 -4.7 phosphoribosylanthranilate isomerase compare
H281DRAFT_06075 -4.2 -9.9 3-isopropylmalate dehydratase, large subunit compare
H281DRAFT_03925 -4.2 -8.6 chorismate mutase compare
H281DRAFT_06060 -4.2 -8.8 amidophosphoribosyltransferase compare
H281DRAFT_02374 -4.1 -9.6 choline dehydrogenase conserved
H281DRAFT_06073 -4.1 -4.5 3-isopropylmalate dehydratase, small subunit compare
H281DRAFT_00465 -4.1 -3.5 PAS/PAC sensor signal transduction histidine kinase /multi-sensor signal transduction histidine kinase compare
H281DRAFT_05712 -3.9 -4.8 indole-3-glycerol phosphate synthase compare
H281DRAFT_04082 -3.9 -6.9 ATP-dependent Clp protease ATP-binding subunit ClpA compare
H281DRAFT_02373 -3.9 -11.0 methylmalonate-semialdehyde dehydrogenase [acylating] compare
H281DRAFT_04553 -3.8 -6.8 ketol-acid reductoisomerase compare
H281DRAFT_06264 -3.7 -3.2 glutamate 5-kinase compare
H281DRAFT_04120 -3.7 -6.4 argininosuccinate synthase compare
H281DRAFT_00120 -3.6 -5.6 sirohydrochlorin cobaltochelatase compare
H281DRAFT_04679 -3.6 -4.2 pyrroline-5-carboxylate reductase compare
H281DRAFT_00116 -3.5 -2.6 phosphoadenylylsulfate reductase (thioredoxin) compare
H281DRAFT_00580 -3.5 -9.0 isocitrate lyase compare
H281DRAFT_02215 -3.4 -6.5 methionine biosynthesis protein MetW compare
H281DRAFT_04974 -3.4 -8.5 aromatic-amino-acid transaminase compare
H281DRAFT_00194 -3.4 -2.1 argininosuccinate lyase compare
H281DRAFT_00385 -3.3 -7.7 2-isopropylmalate synthase compare
H281DRAFT_00118 -3.2 -7.5 sulfate adenylyltransferase subunit 1 compare
H281DRAFT_03610 -3.1 -5.3 squalene-hopene/tetraprenyl-beta-curcumene cyclase compare
H281DRAFT_00860 -3.0 -2.8 phosphoserine phosphatase compare
H281DRAFT_00627 -3.0 -10.9 phosphoenolpyruvate synthase compare
H281DRAFT_00114 -2.9 -5.5 sulfite reductase (NADPH) beta subunit compare
H281DRAFT_04635 -2.9 -2.8 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) compare
H281DRAFT_00117 -2.8 -6.4 sulfate adenylyltransferase subunit 2 compare
H281DRAFT_05621 -2.8 -1.7 glutamate synthase (NADH) small subunit compare
H281DRAFT_00395 -2.8 -7.8 hydroxymethylpyrimidine synthase compare
H281DRAFT_00851 -2.6 -14.5 polyhydroxyalkanoate synthase compare
H281DRAFT_04499 -2.6 -17.1 GTP pyrophosphokinase compare
H281DRAFT_04388 -2.5 -3.1 trehalose 6-phosphatase (EC 3.1.3.12) compare
H281DRAFT_05815 -2.3 -4.4 5,10-methenyltetrahydrofolate synthetase compare
H281DRAFT_02205 -2.1 -1.5 transcriptional regulator, TraR/DksA family compare
H281DRAFT_00853 -2.0 -1.6 3-oxoacyl-[acyl-carrier-protein] reductase /acetoacetyl-CoA reductase compare
H281DRAFT_00529 -2.0 -5.8 KUP system potassium uptake protein compare
H281DRAFT_04021 -2.0 -3.7 3,4-dihydroxy-2-butanone 4-phosphate synthase /GTP cyclohydrolase II compare
H281DRAFT_00852 -1.9 -7.5 acetyl-CoA acetyltransferase compare
H281DRAFT_06023 -1.9 -5.4 hypothetical protein compare
H281DRAFT_00450 -1.9 -9.8 Predicted nucleotide-utilizing enzyme compare
H281DRAFT_04707 -1.9 -5.2 HAD-superfamily subfamily IB hydrolase, TIGR01490 compare
H281DRAFT_04552 -1.8 -4.5 acetolactate synthase, small subunit compare
H281DRAFT_00576 -1.8 -10.9 malate synthase compare
H281DRAFT_00963 -1.7 -10.3 malate synthase compare
H281DRAFT_04498 -1.7 -4.1 Enamine deaminase RidA, house cleaning of reactive enamine intermediates, YjgF/YER057c/UK114 family compare
H281DRAFT_00115 -1.7 -1.7 Uncharacterized conserved protein, DUF934 family compare
H281DRAFT_04070 -1.7 -4.4 nicotinate-nucleotide pyrophosphorylase [carboxylating] compare
H281DRAFT_04835 -1.7 -2.6 hypothetical protein compare
H281DRAFT_04071 -1.7 -8.3 quinolinate synthetase compare
H281DRAFT_06315 -1.6 -1.4 glyceraldehyde-3-phosphate dehydrogenase (NAD+) compare
H281DRAFT_06065 -1.6 -5.8 tryptophan synthase, alpha chain compare
H281DRAFT_02087 -1.6 -10.3 isocitrate dehydrogenase kinase/phosphatase conserved
H281DRAFT_02137 -1.5 -4.6 type I restriction enzyme M protein compare
H281DRAFT_02410 -1.5 -6.4 glycine cleavage system H protein compare
H281DRAFT_05199 -1.5 -5.1 transcriptional regulator, TetR family compare
H281DRAFT_02136 -1.5 -2.2 hypothetical protein compare
H281DRAFT_05125 -1.4 -6.3 Transmembrane transcriptional regulator (anti-sigma factor RsiW) compare
H281DRAFT_03266 -1.4 -1.8 Nicotinamidase-related amidase compare
H281DRAFT_04179 -1.4 -4.9 two-component system, OmpR family, sensor kinase compare
H281DRAFT_04069 -1.4 -10.4 L-aspartate oxidase compare
H281DRAFT_05421 -1.4 -2.6 transcriptional regulator, TetR family compare
H281DRAFT_05232 -1.3 -7.4 putative serine protein kinase, PrkA compare
H281DRAFT_03006 -1.3 -4.3 transcriptional regulator, GntR family compare
H281DRAFT_00501 -1.3 -7.1 Carbonic anhydrase or acetyltransferase, isoleucine patch superfamily compare
H281DRAFT_00176 -1.3 -1.3 outer membrane lipoprotein carrier protein compare
H281DRAFT_04719 -1.3 -3.2 TolB protein compare
H281DRAFT_02731 -1.3 -2.2 hypothetical protein compare
H281DRAFT_01111 -1.2 -2.0 transcriptional regulator, DeoR family compare
H281DRAFT_01889 -1.2 -3.2 7-cyano-7-deazaguanine reductase compare
H281DRAFT_02602 -1.2 -2.1 DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain compare
H281DRAFT_01935 -1.2 -5.4 Tetratricopeptide repeat-containing protein compare
H281DRAFT_04687 -1.2 -8.9 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase compare
H281DRAFT_05234 -1.2 -9.1 Stage V sporulation protein SpoVR/YcgB, involved in spore cortex formation compare
H281DRAFT_00854 -1.2 -5.2 polyhydroxyalkanoate synthesis repressor PhaR compare
H281DRAFT_00658 -1.2 -1.6 transcriptional regulator, IclR family compare
H281DRAFT_02193 -1.2 -2.9 hypothetical protein compare
H281DRAFT_05601 -1.1 -2.6 hypothetical protein compare
H281DRAFT_00559 -1.1 -1.2 hypothetical protein compare
H281DRAFT_04219 -1.1 -6.0 Cytochrome c553 compare
H281DRAFT_00885 -1.1 -2.9 two-component system, OmpR family, osmolarity sensor histidine kinase EnvZ compare
H281DRAFT_04953 -1.1 -7.3 acetyl-coenzyme A synthetase compare
H281DRAFT_06347 -1.1 -1.8 hypothetical protein compare
H281DRAFT_06105 -1.1 -3.3 transcriptional regulator, GntR family compare
H281DRAFT_06322 -1.1 -2.8 LPS-assembly lipoprotein compare
H281DRAFT_00578 -1.1 -2.4 transcriptional regulator, LysR family compare
H281DRAFT_02409 -1.1 -8.4 glycine dehydrogenase compare
H281DRAFT_05233 -1.1 -4.5 hypothetical protein compare
H281DRAFT_00041 -1.1 -3.0 Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain compare
H281DRAFT_00444 -1.0 -0.8 N-acetylglutamate synthase compare
H281DRAFT_01148 -1.0 -2.0 DNA-binding response regulator, OmpR family, contains REC and winged-helix (wHTH) domain compare
H281DRAFT_01985 -1.0 -4.6 protoheme IX farnesyltransferase compare
H281DRAFT_01684 -1.0 -3.6 transcriptional regulator, TetR family compare
H281DRAFT_05934 -1.0 -1.8 Uncharacterized conserved protein YbjT, contains NAD(P)-binding and DUF2867 domains compare
H281DRAFT_02201 -0.9 -1.7 hypothetical protein compare
H281DRAFT_01993 -0.9 -5.5 cytochrome c oxidase subunit 1 compare
H281DRAFT_00785 -0.9 -3.8 2-hydroxy-3-oxopropionate reductase compare
H281DRAFT_00075 -0.9 -2.3 Glycosyltransferase involved in cell wall bisynthesis compare
H281DRAFT_03381 -0.9 -4.0 transcriptional regulator, GntR family compare
H281DRAFT_04075 -0.9 -5.6 formyltetrahydrofolate-dependent phosphoribosylglycinamide formyltransferase compare
H281DRAFT_03067 -0.9 -2.7 peroxiredoxin, Ohr subfamily compare
H281DRAFT_01986 -0.9 -4.4 cytochrome c oxidase assembly protein subunit 15 compare
H281DRAFT_01990 -0.9 -6.3 cytochrome c oxidase subunit 3 compare
H281DRAFT_06286 -0.9 -3.0 Thiol-disulfide isomerase or thioredoxin compare
H281DRAFT_05717 -0.9 -5.2 ribulose-5-phosphate 3-epimerase compare
H281DRAFT_04050 -0.9 -1.9 beta-aspartyl-peptidase (threonine type) compare
H281DRAFT_04549 -0.9 -3.1 Protein of unknown function (DUF3619) compare
H281DRAFT_03702 -0.9 -1.4 transcriptional regulator, MarR family compare
H281DRAFT_03005 -0.9 -1.9 hypothetical protein compare
H281DRAFT_04004 -0.9 -2.8 (p)ppGpp synthetase I, SpoT/RelA compare
H281DRAFT_01321 -0.8 -0.8 probable H4MPT-linked C1 transfer pathway protein compare
H281DRAFT_02700 -0.8 -1.1 feruloyl esterase compare
H281DRAFT_02181 -0.8 -2.4 carbon-monoxide dehydrogenase small subunit compare
H281DRAFT_01210 -0.8 -2.8 Protein of unknown function (DUF1488) compare
H281DRAFT_00712 -0.8 -4.8 RNAse R compare
H281DRAFT_06273 -0.8 -2.1 AmpD protein compare
H281DRAFT_00977 -0.8 -2.1 hypothetical protein compare
H281DRAFT_01512 -0.8 -1.8 transcriptional regulator, IclR family compare
H281DRAFT_01749 -0.8 -1.5 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
H281DRAFT_03009 -0.8 -2.3 acetyl coenzyme A synthetase (ADP forming), alpha domain-containing protein compare
H281DRAFT_00809 -0.8 -4.3 alanine-synthesizing transaminase compare
H281DRAFT_06031 -0.8 -3.2 transcriptional regulator, MarR family compare
H281DRAFT_00706 -0.8 -1.1 outer membrane protein compare
H281DRAFT_03220 -0.8 -1.7 4-hydroxy-tetrahydrodipicolinate synthase compare
H281DRAFT_00290 -0.8 -1.0 Cytochrome c553 compare
H281DRAFT_01224 -0.8 -1.3 Predicted metal-dependent hydrolase, TIM-barrel fold compare
H281DRAFT_04220 -0.8 -3.5 Cytochrome c, mono- and diheme variants compare
H281DRAFT_00286 -0.8 -2.0 transaldolase compare
H281DRAFT_01161 -0.8 -2.7 cytochrome b561 compare
H281DRAFT_01298 -0.7 -1.8 beta-RFAP synthase compare
H281DRAFT_02546 -0.7 -1.6 transcriptional regulator, TetR family compare
H281DRAFT_00755 -0.7 -3.7 transcriptional regulator, TetR family compare
H281DRAFT_04623 -0.7 -3.4 transcriptional regulator, TetR family compare
H281DRAFT_00799 -0.7 -5.4 PhoH-like ATPase compare
H281DRAFT_00756 -0.7 -3.9 Enoyl-CoA hydratase/carnithine racemase compare
H281DRAFT_00842 -0.7 -3.2 protein-L-isoaspartate(D-aspartate) O-methyltransferase compare
H281DRAFT_04357 -0.7 -2.7 sigma E regulatory protein, MucB/RseB compare
H281DRAFT_04970 -0.7 -1.1 high-affinity iron transporter compare
H281DRAFT_01135 -0.7 -2.7 Sugar phosphate permease compare
H281DRAFT_04848 -0.7 -2.0 hypothetical protein compare
H281DRAFT_04356 -0.7 -2.0 anti sigma-E protein, RseA compare
H281DRAFT_03615 -0.7 -3.0 hopanoid biosynthesis associated radical SAM protein HpnH compare
H281DRAFT_03226 -0.7 -1.0 mannose-binding protein /fructose-binding protein /ribose-binding protein compare
H281DRAFT_03585 -0.7 -1.6 Polyisoprenoid-binding protein YceI compare
H281DRAFT_06518 -0.7 -2.1 hypothetical protein compare
H281DRAFT_05214 -0.7 -2.1 transcriptional regulator, LacI family compare
H281DRAFT_05159 -0.7 -2.1 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase compare
H281DRAFT_06514 -0.7 -1.6 Glycine/D-amino acid oxidase (deaminating) compare
H281DRAFT_00577 -0.7 -1.3 2-haloacid dehalogenase compare
H281DRAFT_01994 -0.7 -4.4 cytochrome c oxidase subunit 2 compare
H281DRAFT_03547 -0.7 -3.6 Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding Fis domains compare
H281DRAFT_05286 -0.7 -1.6 transcriptional regulator, LysR family compare
H281DRAFT_03274 -0.7 -1.3 hypothetical protein compare
H281DRAFT_02638 -0.7 -3.1 Multicopper oxidase with three cupredoxin domains (includes cell division protein FtsP and spore coat protein CotA) compare
H281DRAFT_03348 -0.7 -1.4 amino acid ABC transporter ATP-binding protein, PAAT family compare
H281DRAFT_06134 -0.7 -1.1 hypothetical protein compare
H281DRAFT_05766 -0.7 -1.1 flagellar basal-body rod protein FlgF compare
H281DRAFT_01235 -0.7 -2.1 DNA-binding protein H-NS compare
H281DRAFT_03588 -0.7 -2.4 transcriptional regulator, XRE family with cupin sensor compare
H281DRAFT_02530 -0.7 -2.8 transcriptional regulator, IclR family compare
H281DRAFT_02231 -0.7 -1.5 7-carboxy-7-deazaguanine synthase, Cx14CxxC type compare
H281DRAFT_00163 -0.7 -4.0 glucokinase /transcriptional regulator, RpiR family compare
H281DRAFT_04278 -0.7 -3.9 6-phosphogluconate dehydratase compare
H281DRAFT_06510 -0.7 -2.2 methyl-accepting chemotaxis protein compare
H281DRAFT_00197 -0.7 -3.9 Phosphoenolpyruvate carboxylase, type 1 compare
H281DRAFT_01687 -0.7 -1.6 carbonic anhydrase compare
H281DRAFT_06266 -0.6 -2.8 putative (di)nucleoside polyphosphate hydrolase compare
H281DRAFT_00378 -0.6 -1.8 glutamate synthase (NADPH/NADH) small chain compare
H281DRAFT_02670 -0.6 -1.0 transcriptional regulator, GntR family compare
H281DRAFT_00123 -0.6 -1.8 aminopeptidase A. Metallo peptidase. MEROPS family M17 compare
H281DRAFT_01094 -0.6 -1.3 protein of unknown function (DUF3331) compare
H281DRAFT_04162 -0.6 -3.0 zinc/manganese transport system substrate-binding protein compare
H281DRAFT_05986 -0.6 -1.8 transcriptional regulator, TetR family compare
H281DRAFT_05351 -0.6 -1.0 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain compare
H281DRAFT_02781 -0.6 -2.7 Response regulator c-di-GMP phosphodiesterase, RpfG family, contains REC and HD-GYP domains compare
H281DRAFT_00769 -0.6 -1.2 hypothetical protein compare
H281DRAFT_05737 -0.6 -2.0 flagellar transcriptional activator FlhD compare


Specific Phenotypes

For 6 genes in this experiment

For carbon source 3-Hydroxypropionate in Paraburkholderia bryophila 376MFSha3.1

For carbon source 3-Hydroxypropionate across organisms