Experiment set6IT016 for Klebsiella michiganensis M5al

Compare to:

L-Leucine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS02995 -7.3 -8.4 aspartate carbamoyltransferase compare
BWI76_RS25115 -6.8 -8.0 argininosuccinate synthase compare
BWI76_RS04470 -6.8 -11.4 carbamoyl phosphate synthase large subunit compare
BWI76_RS00390 -6.6 -6.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS18950 -6.4 -6.1 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS00855 -6.3 -8.6 argininosuccinate lyase compare
BWI76_RS18930 -6.2 -5.4 histidinol-phosphate transaminase compare
BWI76_RS23360 -6.2 -4.2 diaminopimelate decarboxylase compare
BWI76_RS04160 -5.7 -6.6 phosphoserine phosphatase compare
BWI76_RS27385 -5.5 -8.3 orotate phosphoribosyltransferase compare
BWI76_RS03010 -5.4 -7.0 ornithine carbamoyltransferase compare
BWI76_RS09755 -5.4 -11.0 phosphoserine transaminase compare
BWI76_RS17720 -5.3 -1.9 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS04465 -5.3 -7.2 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09645 -5.2 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS20895 -5.0 -5.3 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS00400 -5.0 -3.1 glutamine synthetase compare
BWI76_RS01615 -4.9 -9.9 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS05015 -4.8 -3.9 transcriptional regulator compare
BWI76_RS00850 -4.7 -6.6 acetylglutamate kinase compare
BWI76_RS01350 -4.6 -1.7 NAD(P)H-flavin reductase compare
BWI76_RS08385 -4.6 -5.1 citrate (Si)-synthase compare
BWI76_RS09910 -4.6 -15.5 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS18935 -4.4 -7.2 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS23920 -4.4 -6.4 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS08180 -4.4 -9.4 asparagine synthase B compare
BWI76_RS21265 -4.4 -14.3 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18940 -4.3 -5.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS20350 -4.3 -6.6 amidophosphoribosyltransferase compare
BWI76_RS05200 -4.3 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS18925 -4.3 -5.6 histidinol dehydrogenase compare
BWI76_RS23220 -4.2 -8.0 amino-acid N-acetyltransferase compare
BWI76_RS08525 -4.2 -5.8 colicin transporter compare
BWI76_RS20965 -4.2 -4.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS09660 -4.1 -2.8 DNA translocase FtsK compare
BWI76_RS08520 -4.0 -3.0 colicin transporter TolQ compare
BWI76_RS01610 -4.0 -7.9 phosphoribosylamine--glycine ligase compare
BWI76_RS00385 -3.9 -6.5 nitrogen assimilation regulatory protein compare
BWI76_RS23240 -3.9 -4.6 exonuclease V subunit gamma compare
BWI76_RS07070 -3.8 -4.9 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS10990 -3.8 -4.6 dihydroorotase compare
BWI76_RS23230 -3.7 -5.0 exodeoxyribonuclease V subunit beta compare
BWI76_RS00845 -3.7 -8.0 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS11965 -3.5 -4.4 orotidine-5'-phosphate decarboxylase compare
BWI76_RS19495 -3.4 -1.7 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS17980 -3.4 -6.8 RNA chaperone ProQ compare
BWI76_RS27390 -3.3 -5.0 ribonuclease PH compare
BWI76_RS00835 -3.3 -10.6 phosphoenolpyruvate carboxylase compare
BWI76_RS25285 -3.3 -1.7 HPr family phosphocarrier protein compare
BWI76_RS22805 -3.2 -10.1 GTP diphosphokinase compare
BWI76_RS00975 -3.1 -9.7 dihydroxy-acid dehydratase compare
BWI76_RS20355 -3.0 -2.6 colicin V production protein compare
BWI76_RS08530 -3.0 -3.4 protein TolA compare
BWI76_RS18920 -3.0 -4.9 ATP phosphoribosyltransferase compare
BWI76_RS05840 -2.9 -6.5 glutamate 5-kinase compare
BWI76_RS25960 -2.9 -4.4 NUDIX hydrolase compare
BWI76_RS05835 -2.7 -3.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS24240 -2.7 -2.6 hypothetical protein compare
BWI76_RS04645 -2.7 -5.4 3-dehydroquinase compare
BWI76_RS00345 -2.7 -3.9 protein disulfide oxidoreductase DsbA compare
BWI76_RS25600 -2.7 -1.7 tRNA-Thr compare
BWI76_RS09970 -2.6 -4.7 porin OmpA compare
BWI76_RS01210 -2.6 -2.6 tyrosine recombinase XerC compare
BWI76_RS06530 -2.5 -4.1 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS18630 -2.5 -8.0 nitrogen assimilation transcriptional regulator compare
BWI76_RS15825 -2.4 -3.0 hypothetical protein compare
BWI76_RS21580 -2.4 -2.9 SsrA-binding protein compare
BWI76_RS07065 -2.4 -7.5 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS20650 -2.4 -3.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS06535 -2.3 -5.2 endopeptidase La compare
BWI76_RS06525 -2.3 -4.4 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS23365 -2.3 -7.1 LysR family transcriptional regulator compare
BWI76_RS24945 -2.2 -1.6 glutamine amidotransferase compare
BWI76_RS25065 -2.2 -4.4 polyribonucleotide nucleotidyltransferase compare
BWI76_RS00840 -2.2 -9.5 acetylornithine deacetylase compare
BWI76_RS08535 -2.2 -2.7 translocation protein TolB compare
BWI76_RS02530 -2.2 -2.1 tRNA dimethylallyltransferase compare
BWI76_RS23480 -2.1 -10.6 EAL domain-containing protein compare
BWI76_RS23265 -2.0 -4.3 hypothetical protein compare
BWI76_RS17345 -2.0 -8.0 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS16235 -2.0 -4.7 membrane protein compare
BWI76_RS11840 -2.0 -3.3 tryptophan synthase subunit alpha compare
BWI76_RS11850 -2.0 -7.2 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS15835 -2.0 -1.6 hypothetical protein compare
BWI76_RS06765 -2.0 -3.8 transcriptional regulator compare
BWI76_RS16965 -1.9 -5.6 murein lipoprotein compare
BWI76_RS00965 -1.9 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS16485 -1.9 -2.4 ribonuclease T compare
BWI76_RS17735 -1.9 -4.0 D-amino acid dehydrogenase small subunit compare
BWI76_RS20360 -1.8 -1.4 cell division protein DedD compare
BWI76_RS09760 -1.8 -3.3 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS10835 -1.8 -1.8 hypothetical protein compare
BWI76_RS24235 -1.7 -6.1 Branched-chain-amino-acid transaminase (EC 2.6.1.42) (from data) conserved
BWI76_RS26570 -1.7 -2.5 anion permease compare
BWI76_RS02410 -1.7 -1.7 EF-P beta-lysylation protein EpmB compare
BWI76_RS05120 -1.6 -7.5 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS20205 -1.6 -4.6 aminotransferase AlaT compare
BWI76_RS22690 -1.5 -2.2 adenylyl-sulfate kinase compare
BWI76_RS00990 -1.5 -5.2 ketol-acid reductoisomerase compare
BWI76_RS01200 -1.5 -1.4 diaminopimelate epimerase compare
BWI76_RS25280 -1.5 -1.9 RNase adaptor protein RapZ compare
BWI76_RS26085 -1.5 -2.2 3-dehydroquinate synthase compare
BWI76_RS05990 -1.5 -4.1 branched-chain amino acid ABC transporter permease compare
BWI76_RS04255 -1.5 -6.6 threonine synthase compare
BWI76_RS04270 -1.5 -3.0 transaldolase compare
BWI76_RS09960 -1.4 -2.4 Lon protease compare
BWI76_RS11845 -1.4 -3.4 tryptophan synthase subunit beta compare
BWI76_RS05985 -1.4 -4.2 branched-chain amino acid ABC transporter permease compare
BWI76_RS17975 -1.4 -2.6 tail-specific protease compare
BWI76_RS27440 -1.4 -4.3 DNA helicase RecG compare
BWI76_RS18770 -1.4 -1.2 DNA gyrase inhibitor compare
BWI76_RS12090 -1.4 -1.6 HNH endonuclease compare
BWI76_RS13595 -1.3 -3.8 transcriptional regulator compare
BWI76_RS15810 -1.3 -4.4 hypothetical protein compare
BWI76_RS11810 -1.3 -2.0 outer membrane protein OmpW compare
BWI76_RS15830 -1.3 -2.8 hypothetical protein compare
BWI76_RS22755 -1.3 -4.7 phosphoadenosine phosphosulfate reductase compare
BWI76_RS13590 -1.3 -1.6 hypothetical protein compare
BWI76_RS20640 -1.3 -3.8 cysteine synthase A compare
BWI76_RS24340 -1.3 -4.6 two-component sensor histidine kinase compare
BWI76_RS26055 -1.3 -4.6 siroheme synthase compare
BWI76_RS06015 -1.3 -1.1 hypothetical protein compare
BWI76_RS15840 -1.2 -3.1 prophage protein compare
BWI76_RS21370 -1.2 -2.2 ATP-dependent RNA helicase SrmB compare
BWI76_RS04060 -1.2 -1.5 hypothetical protein compare
BWI76_RS09505 -1.2 -1.8 arginine transporter permease subunit ArtM compare
BWI76_RS00970 -1.2 -2.4 branched chain amino acid aminotransferase compare
BWI76_RS06395 -1.2 -2.0 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS03665 -1.1 -0.9 ABC transporter ATP-binding protein compare
BWI76_RS17310 -1.1 -2.5 AsnC family transcriptional regulator compare
BWI76_RS14650 -1.1 -1.7 helix-turn-helix transcriptional regulator compare
BWI76_RS26075 -1.1 -3.3 DNA adenine methylase compare
BWI76_RS18755 -1.1 -1.2 adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase compare
BWI76_RS19870 -1.1 -1.6 malate:quinone oxidoreductase compare
BWI76_RS06770 -1.1 -5.4 Hha toxicity attenuator compare
BWI76_RS06800 -1.1 -1.2 DUF2496 domain-containing protein compare
BWI76_RS11040 -1.1 -2.1 ribonuclease E compare
BWI76_RS08380 -1.1 -1.5 endonuclease VIII compare
BWI76_RS26395 -1.1 -3.5 cell division protein FtsE compare
BWI76_RS00760 -1.1 -2.7 cell division protein FtsN compare
BWI76_RS15060 -1.1 -2.0 MarR family transcriptional regulator compare
BWI76_RS21350 -1.0 -1.5 anti-RNA polymerase sigma factor SigE compare
BWI76_RS13435 -1.0 -1.3 hypothetical protein compare
BWI76_RS09520 -1.0 -2.0 arginine ABC transporter ATP-binding protein ArtP compare
BWI76_RS25070 -1.0 -1.2 hypothetical protein compare
BWI76_RS13445 -1.0 -1.7 alpha/beta hydrolase compare
BWI76_RS17780 -1.0 -3.1 septum formation inhibitor compare
BWI76_RS19840 -1.0 -1.1 hypothetical protein compare
BWI76_RS23270 -1.0 -6.1 phosphoenolpyruvate--protein phosphotransferase PtsP compare
BWI76_RS13095 -1.0 -1.7 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS05975 -1.0 -3.0 ABC transporter ATP-binding protein compare
BWI76_RS19375 -1.0 -1.5 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS21565 -1.0 -1.1 outer membrane protein assembly factor BamE compare
BWI76_RS19845 -1.0 -2.5 phosphatase compare
BWI76_RS15630 -1.0 -3.4 hypothetical protein compare
BWI76_RS13480 -1.0 -1.3 XRE family transcriptional regulator compare
BWI76_RS07640 -1.0 -1.5 short chain dehydrogenase compare
BWI76_RS26405 -0.9 -1.0 16S rRNA (guanine(966)-N(2))-methyltransferase compare
BWI76_RS17195 -0.9 -2.0 hypothetical protein compare
BWI76_RS06005 -0.9 -3.9 ethanolamine ammonia lyase large subunit compare
BWI76_RS25060 -0.9 -1.8 lipoprotein NlpI compare
BWI76_RS14980 -0.9 -1.4 hypothetical protein compare
BWI76_RS09940 -0.9 -2.6 paraquat-inducible protein B compare
BWI76_RS10745 -0.9 -0.9 hypothetical protein compare
BWI76_RS14415 -0.9 -2.1 transcriptional regulator, TetR family protein compare
BWI76_RS12895 -0.9 -2.3 hypothetical protein compare
BWI76_RS20380 -0.9 -1.1 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS04305 -0.9 -1.0 molecular chaperone DnaJ compare
BWI76_RS22760 -0.9 -3.8 sulfite reductase subunit beta compare
BWI76_RS21505 -0.9 -0.9 hypothetical protein compare
BWI76_RS02545 -0.9 -4.4 protease modulator HflK compare
BWI76_RS26455 -0.9 -3.2 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS04515 -0.9 -1.1 Co2+/Mg2+ efflux protein ApaG compare
BWI76_RS18710 -0.9 -5.5 GGDEF-domain containing protein compare
BWI76_RS17785 -0.9 -3.6 septum site-determining protein MinD compare
BWI76_RS01885 -0.9 -1.0 CsbD family protein compare
BWI76_RS07645 -0.9 -1.6 short-chain dehydrogenase/reductase compare
BWI76_RS08925 -0.8 -3.6 DNA-binding protein YbiB compare
BWI76_RS19040 -0.8 -4.4 hypothetical protein compare
BWI76_RS18415 -0.8 -2.1 very short patch repair endonuclease compare
BWI76_RS18955 -0.8 -1.6 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS02330 -0.8 -4.2 aspartate ammonia-lyase compare
BWI76_RS20050 -0.8 -1.2 hypothetical protein compare
BWI76_RS02540 -0.8 -2.8 GTPase HflX compare
BWI76_RS13970 -0.8 -1.5 ABC transporter compare
BWI76_RS05045 -0.8 -1.0 general secretion pathway protein GspM compare
BWI76_RS12450 -0.8 -2.6 phage shock protein PspA compare
BWI76_RS00940 -0.8 -3.5 transcriptional regulator HdfR compare
BWI76_RS09730 -0.8 -1.2 pyruvate formate lyase 1-activating protein compare
BWI76_RS24725 -0.8 -3.8 altronate hydrolase compare
BWI76_RS19685 -0.8 -3.4 lysine transporter compare
BWI76_RS14825 -0.8 -1.9 dienelactone hydrolase family protein compare
BWI76_RS20695 -0.8 -2.3 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS12335 -0.8 -3.0 hypothetical protein compare
BWI76_RS07725 -0.8 -1.0 iron-enterobactin transporter permease compare
BWI76_RS07110 -0.8 -2.4 DNA-binding protein compare
BWI76_RS14490 -0.8 -1.7 ABC transporter substrate-binding protein compare
BWI76_RS16935 -0.8 -1.1 shikimate dehydrogenase compare
BWI76_RS09195 -0.8 -1.1 N-acetyltransferase compare
BWI76_RS17200 -0.8 -1.2 hypothetical protein compare


Specific Phenotypes

For 6 genes in this experiment

For nitrogen source L-Leucine in Klebsiella michiganensis M5al

For nitrogen source L-Leucine across organisms