Experiment set6IT015 for Methanococcus maripaludis S2

200 most important genes:

gene	name	fitness	t score	description
MMP_RS01175		-5.1	-7.2	triphosphoribosyl-dephospho-CoA synthase
MMP_RS06355		-4.9	-5.1	molybdenum cofactor biosynthesis protein MoaE
MMP_RS06680		-4.4	-22.0	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS06685		-4.2	-19.1	formate dehydrogenase H subunit alpha selenocysteine-containing
MMP_RS06700		-4.0	-19.1	hypothetical protein
MMP_RS06350		-3.9	-12.4	HesA/MoeB/ThiF family protein
MMP_RS07635		-3.8	-13.0	MogA/MoaB family molybdenum cofactor biosynthesis protein
MMP_RS01020		-3.7	-2.0	3 4-dihydroxy-2-butanone-4-phosphate synthase
MMP_RS05515		-3.7	-11.8	cyclic pyranopterin monophosphate synthase MoaC
MMP_RS03015		-3.7	-16.1	GTP 3' 8-cyclase MoaA
MMP_RS06345		-3.6	-15.2	formate dehydrogenase accessory sulfurtransferase FdhD
MMP_RS07735		-3.5	-1.8	2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
MMP_RS02010		-3.3	-15.2	PHP domain-containing protein
MMP_RS01985		-3.2	-11.2	F420-dependent methylenetetrahydromethanopterin dehydrogenase
MMP_RS06715		-3.2	-20.0	cache domain-containing protein
MMP_RS02280		-3.2	-1.9	DUF211 domain-containing protein
MMP_RS08820		-3.1	-7.6	hypothetical protein
MMP_RS04900		-3.0	-23.0	hypothetical protein
MMP_RS06295		-3.0	-9.2	methanogenesis marker 14 protein
MMP_RS08635		-2.9	-3.6	UbiA family prenyltransferase
MMP_RS06720		-2.9	-11.5	response regulator transcription factor
MMP_RS01385		-2.9	-1.3	imidazole glycerol phosphate synthase subunit HisH
MMP_RS06975		-2.9	-3.0	sulfide-dependent adenosine diphosphate thiazole synthase
MMP_RS07005		-2.8	-1.3	4Fe-4S binding protein
MMP_RS04890		-2.8	-1.8	adenylyltransferase/cytidyltransferase family protein
MMP_RS03435		-2.7	-3.5	ketol-acid reductoisomerase
MMP_RS04605		-2.7	-7.4	cobalt ECF transporter T component CbiQ
MMP_RS00040		-2.7	-5.5	TIGR03576 family pyridoxal phosphate-dependent enzyme
MMP_RS01005		-2.6	-2.5	riboflavin synthase
MMP_RS02240		-2.6	-6.7	methanogenesis marker 7 protein
MMP_RS05920		-2.6	-1.2	50S ribosomal protein L37e
MMP_RS03315		-2.6	-2.1	ferrous iron transport protein A
MMP_RS00695		-2.5	-1.9	biotin--[acetyl-CoA-carboxylase] ligase
MMP_RS07445		-2.5	-7.7	helix-turn-helix domain-containing protein
MMP_RS02195		-2.4	-8.0	tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
MMP_RS00300		-2.4	-1.5	6 7-dimethyl-8-ribityllumazine synthase
MMP_RS01500		-2.4	-4.4	CBS domain-containing protein
MMP_RS02340		-2.4	-3.8	DNA-directed RNA polymerase subunit E''
MMP_RS07605		-2.4	-4.4	diadenylate cyclase
MMP_RS06285		-2.4	-5.2	precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
MMP_RS03600		-2.4	-3.8	triose-phosphate isomerase
MMP_RS07845		-2.3	-4.2	LL-diaminopimelate aminotransferase
MMP_RS01220		-2.3	-11.4	hypothetical protein
MMP_RS08460		-2.3	-4.6	proteasome-activating nucleotidase
MMP_RS00685		-2.3	-5.7	2-phospho-L-lactate guanylyltransferase
MMP_RS04585		-2.3	-13.6	AIR synthase related protein
MMP_RS01980		-2.3	-15.5	trimeric intracellular cation channel family protein
MMP_RS07600		-2.2	-5.8	Ni-sirohydrochlorin a c-diamide synthase
MMP_RS01755		-2.2	-2.5	DUF2097 domain-containing protein
MMP_RS06705		-2.2	-10.3	formate/nitrite transporter family protein
MMP_RS07730		-2.2	-3.3	pyruvate synthase subunit beta
MMP_RS00115		-2.2	-14.6	radical SAM protein
MMP_RS07765		-2.2	-10.0	sodium:alanine symporter family protein
MMP_RS04615		-2.2	-5.9	PDGLE domain-containing protein
MMP_RS00895		-2.2	-6.2	hypothetical protein
MMP_RS08745		-2.1	-8.0	CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
MMP_RS03025		-2.1	-7.7	molybdenum cofactor guanylyltransferase
MMP_RS07525		-2.1	-10.4	4Fe-4S binding protein
MMP_RS01225		-2.0	-7.5	DUF5379 domain-containing protein
MMP_RS01265		-2.0	-2.7	hypothetical protein
MMP_RS06105		-2.0	-10.7	hydrogenase maturation peptidase HycI
MMP_RS04620		-2.0	-11.8	cobalt transporter CbiM
MMP_RS06885		-2.0	-4.6	50S ribosome-binding GTPase
MMP_RS08300		-1.9	-2.1	metal-sulfur cluster assembly factor
MMP_RS08715		-1.9	-2.3	formylmethanofuran dehydrogenase subunit B
MMP_RS07630		-1.9	-2.8	ATP-binding cassette domain-containing protein
MMP_RS00295		-1.8	-3.8	gamma carbonic anhydrase family protein
MMP_RS02235		-1.8	-10.2	CBS domain-containing protein
MMP_RS02355		-1.8	-3.4	30S ribosomal protein S27ae
MMP_RS08645		-1.8	-8.4	UPF0179 family protein
MMP_RS09020		-1.8	-2.4	hypothetical protein
MMP_RS02800		-1.8	-6.3	nucleotidyltransferase domain-containing protein
MMP_RS01325		-1.8	-3.2	dihydroneopterin aldolase family protein
MMP_RS04775		-1.8	-4.1	adenosylhomocysteinase
MMP_RS01545		-1.8	-1.8	CBS domain-containing protein
MMP_RS06730		-1.7	-2.1	phosphopantothenate/pantothenate synthetase
MMP_RS08790		-1.7	-3.5	translation initiation factor IF-2 subunit alpha
MMP_RS03400		-1.7	-2.9	archease
MMP_RS02190		-1.7	-3.7	sulfopyruvate decarboxylase subunit alpha
MMP_RS03640		-1.7	-3.6	archaeal proteasome endopeptidase complex subunit beta
MMP_RS04780		-1.7	-3.6	ribonuclease P
MMP_RS01380		-1.7	-5.1	PHP domain-containing protein
MMP_RS08720		-1.6	-2.4	4Fe-4S binding protein
MMP_RS06400		-1.6	-1.9	4Fe-4S binding protein
MMP_RS00620		-1.6	-9.8	4Fe-4S binding protein
MMP_RS06215		-1.6	-3.8	30S ribosomal protein S6e
MMP_RS05540		-1.6	-3.6	hypothetical protein
MMP_RS08435		-1.5	-3.0	Era-like GTP-binding protein
MMP_RS02165		-1.5	-5.7	tRNA-dihydrouridine synthase
MMP_RS05875		-1.5	-5.5	hydroxyethylthiazole kinase
MMP_RS06270		-1.5	-4.7	TIGR00300 family protein
MMP_RS06475		-1.5	-4.4	FAD-dependent oxidoreductase
MMP_RS04500		-1.5	-11.6	adenosylmethionine--8-amino-7-oxononanoate transaminase
MMP_RS06895		-1.5	-1.6	selenocysteine-specific translation elongation factor
MMP_RS03960		-1.5	-1.6	hypothetical protein
MMP_RS00305		-1.5	-2.3	phosphoribosyl-ATP diphosphatase
MMP_RS06020		-1.5	-5.0	archaeoflavoprotein AfpA
MMP_RS06200		-1.5	-9.2	M24 family metallopeptidase
MMP_RS05245		-1.5	-9.9	archaeosine biosynthesis radical SAM protein RaSEA
MMP_RS06925		-1.4	-3.0	ribonuclease VapC4
MMP_RS03445		-1.4	-1.4	methanogenesis marker 17 protein
MMP_RS06865		-1.4	-1.4	HypC/HybG/HupF family hydrogenase formation chaperone
MMP_RS05430		-1.4	-4.2	TIGR00288 family NYN domain-containing protein
MMP_RS06370		-1.4	-6.1	biotin synthase BioB
MMP_RS03580		-1.4	-3.9	signal recognition particle-docking protein FtsY
MMP_RS08105		-1.3	-7.9	6-carboxyhexanoate--CoA ligase
MMP_RS02345		-1.3	-3.1	GTP-dependent dephospho-CoA kinase family protein
MMP_RS00110		-1.3	-3.2	hypothetical protein
MMP_RS07365		-1.3	-9.7	2-phosphoglycerate kinase
MMP_RS04685		-1.3	-3.5	DUF126 domain-containing protein
MMP_RS08100		-1.3	-7.3	8-amino-7-oxononanoate synthase
MMP_RS07545		-1.3	-1.6	HTH domain-containing protein
MMP_RS05765		-1.3	-6.4	M42 family metallopeptidase
MMP_RS01800		-1.3	-3.0	TIGR00303 family protein
MMP_RS07755		-1.3	-1.7	DUF555 domain-containing protein
MMP_RS04870		-1.3	-4.3	TIGR02253 family HAD-type hydrolase
MMP_RS06625		-1.3	-2.4	DNA primase
MMP_RS05510		-1.3	-4.0	Rrf2 family transcriptional regulator
MMP_RS01610		-1.3	-3.6	hypothetical protein
MMP_RS01725		-1.2	-4.4	class I SAM-dependent methyltransferase family protein
MMP_RS07380		-1.2	-2.6	transcription elongation factor Spt5
MMP_RS03035		-1.2	-2.8	4-hydroxy-tetrahydrodipicolinate synthase
MMP_RS01830		-1.2	-2.4	tRNA-Val
MMP_RS04710		-1.2	-2.3	hypothetical protein
MMP_RS08095		-1.2	-6.1	dethiobiotin synthase
MMP_RS07575		-1.2	-3.5	RNA ligase partner protein
MMP_RS01365		-1.1	-2.7	archaeal proteasome endopeptidase complex subunit alpha
MMP_RS00555		-1.1	-4.5	MFS transporter
MMP_RS06175		-1.1	-5.1	winged helix-turn-helix transcriptional regulator
MMP_RS02135		-1.1	-2.5	DUF5612 domain-containing protein
MMP_RS01795		-1.1	-2.1	methanogenesis marker 6 protein
MMP_RS06840		-1.1	-1.2	DNA-directed RNA polymerase subunit N
MMP_RS06930		-1.1	-7.4	MBL fold metallo-hydrolase
MMP_RS07750		-1.1	-4.4	DUF357 domain-containing protein
MMP_RS00060		-1.1	-1.9	3-dehydroquinate synthase II
MMP_RS06230		-1.1	-2.5	helix-turn-helix domain-containing protein
MMP_RS07645		-1.1	-3.2	aldehyde dehydrogenase family protein
MMP_RS03205		-1.0	-2.0	peptidyl-tRNA hydrolase Pth2
MMP_RS02245		-1.0	-2.8	hypothetical protein
MMP_RS05500		-1.0	-5.4	2-isopropylmalate synthase
MMP_RS03475		-1.0	-0.7	hypothetical protein
MMP_RS01250		-1.0	-4.2	tRNA (guanine(26)-N(2))-dimethyltransferase
MMP_RS07555		-1.0	-0.8	monovalent cation/H+ antiporter subunit E
MMP_RS08240		-1.0	-3.8	methanogenesis marker 16 metalloprotein
MMP_RS06340		-1.0	-5.9	phosphoadenosine phosphosulfate reductase family protein
MMP_RS03485		-1.0	-2.3	TIGR00267 family protein
MMP_RS07200		-1.0	-4.6	[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
MMP_RS07435		-1.0	-2.1	GMP synthase subunit A
MMP_RS00290		-1.0	-5.6	hypothetical protein
MMP_RS00130		-1.0	-1.4	nickel-responsive transcriptional regulator NikR
MMP_RS08200		-0.9	-7.5	archaeosine synthase subunit alpha
MMP_RS08940		-0.9	-1.5	MetS family NSS transporter small subunit
MMP_RS05550		-0.9	-0.8	cation:proton antiporter
MMP_RS07685		-0.9	-4.6	TIGR01212 family radical SAM protein
MMP_RS08210		-0.9	-2.7	phosphatidylglycerophosphatase A
MMP_RS07775		-0.9	-3.3	alanine dehydrogenase
MMP_RS03300		-0.9	-1.0	TOBE domain-containing protein
MMP_RS05555		-0.9	-1.5	DUF4040 domain-containing protein
MMP_RS03590		-0.9	-5.1	METTL5 family protein
MMP_RS06525		-0.9	-1.4	YciI family protein
MMP_RS08690		-0.9	-4.4	RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
MMP_RS02900		-0.9	-0.6	imidazoleglycerol-phosphate dehydratase HisB
MMP_RS06915		-0.8	-3.9	metallophosphoesterase
MMP_RS00050		-0.8	-4.5	AarF/UbiB family protein
MMP_RS02605		-0.8	-1.0	MotA/TolQ/ExbB proton channel family protein
MMP_RS07425		-0.8	-4.0	GTP-binding protein
MMP_RS05425		-0.8	-3.3	monovalent cation/H+ antiporter complex subunit F
MMP_RS05345		-0.8	-4.3	hypothetical protein
MMP_RS05545		-0.8	-3.2	pyridoxal phosphate-dependent aminotransferase
MMP_RS06630		-0.8	-0.9	UPF0058 family protein
MMP_RS01075		-0.8	-2.0	hypothetical protein
MMP_RS00985		-0.8	-2.8	CDC48 family AAA ATPase
MMP_RS01195		-0.8	-1.1	metalloregulator ArsR/SmtB family transcription factor
MMP_RS02405		-0.8	-3.0	hypothetical protein
MMP_RS07195		-0.8	-4.1	M20 family metallo-hydrolase
MMP_RS07860		-0.8	-0.9	hypothetical protein
MMP_RS01440		-0.8	-4.8	NAAT family transporter
MMP_RS07390		-0.8	-1.8	cell division protein FtsZ
MMP_RS03095		-0.7	-4.0	diphthine synthase
MMP_RS05845		-0.7	-1.3	tRNA-intron lyase
MMP_RS07710		-0.7	-3.4	cell division protein FtsZ
MMP_RS06855		-0.7	-5.0	hypothetical protein
MMP_RS02170		-0.7	-2.1	CBS domain-containing protein
MMP_RS08165		-0.7	-1.5	phosphoglycerate dehydrogenase
MMP_RS00035		-0.7	-4.9	DUF2098 family protein
MMP_RS00515		-0.7	-0.8	DUF655 domain-containing protein
MMP_RS01790		-0.7	-3.4	restriction endonuclease
MMP_RS06980		-0.7	-3.4	tRNA 2-thiocytidine biosynthesis TtcA family protein
MMP_RS04695		-0.7	-3.3	selenide water dikinase SelD
MMP_RS05865		-0.7	-2.2	hypothetical protein
MMP_RS01085		-0.7	-1.4	hypothetical protein
MMP_RS01840		-0.7	-4.1	TIGR00289 family protein
MMP_RS03210		-0.6	-4.6	tRNA guanosine(15) transglycosylase TgtA
MMP_RS05800		-0.6	-4.7	B12-binding domain-containing radical SAM protein
MMP_RS00705		-0.6	-1.8	hypothetical protein
MMP_RS07790		-0.6	-3.7	segregation/condensation protein A
MMP_RS00720		-0.6	-3.3	metal-dependent hydrolase
MMP_RS01575		-0.6	-3.2	aldolase
MMP_RS01045		-0.6	-3.6	diphthamide biosynthesis enzyme Dph2
MMP_RS08595		-0.6	-0.9	flagellar protein C

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments