Experiment set6IT015 for Klebsiella michiganensis M5al

Compare to:

L-Isoleucine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS04160 -7.1 -7.4 phosphoserine phosphatase compare
BWI76_RS11965 -7.0 -5.2 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18950 -6.8 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS01210 -6.1 -3.6 tyrosine recombinase XerC compare
BWI76_RS27385 -6.1 -7.2 orotate phosphoribosyltransferase compare
BWI76_RS18935 -6.0 -9.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS02995 -6.0 -9.5 aspartate carbamoyltransferase compare
BWI76_RS05015 -6.0 -4.1 transcriptional regulator compare
BWI76_RS26085 -5.9 -3.7 3-dehydroquinate synthase compare
BWI76_RS04470 -5.8 -10.9 carbamoyl phosphate synthase large subunit compare
BWI76_RS18930 -5.8 -4.2 histidinol-phosphate transaminase compare
BWI76_RS00385 -5.7 -10.1 nitrogen assimilation regulatory protein compare
BWI76_RS20895 -5.6 -6.9 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS08385 -5.5 -4.9 citrate (Si)-synthase compare
BWI76_RS10990 -5.5 -2.9 dihydroorotase compare
BWI76_RS18940 -5.3 -4.5 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS23360 -5.3 -5.2 diaminopimelate decarboxylase compare
BWI76_RS09645 -5.3 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS00965 -5.1 -1.8 acetolactate synthase 2 small subunit compare
BWI76_RS04465 -5.0 -5.3 carbamoyl-phosphate synthase small subunit compare
BWI76_RS00400 -5.0 -3.1 glutamine synthetase compare
BWI76_RS05835 -5.0 -4.2 gamma-glutamyl-phosphate reductase compare
BWI76_RS08180 -4.7 -9.0 asparagine synthase B compare
BWI76_RS09755 -4.6 -8.9 phosphoserine transaminase compare
BWI76_RS20350 -4.6 -7.4 amidophosphoribosyltransferase compare
BWI76_RS09910 -4.5 -14.3 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS01615 -4.5 -11.4 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS25115 -4.5 -10.4 argininosuccinate synthase compare
BWI76_RS00390 -4.5 -6.5 two-component system sensor histidine kinase NtrB compare
BWI76_RS00855 -4.4 -9.4 argininosuccinate lyase compare
BWI76_RS23920 -4.4 -3.9 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS00970 -4.3 -6.6 branched chain amino acid aminotransferase compare
BWI76_RS21265 -4.3 -10.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS18925 -4.3 -7.7 histidinol dehydrogenase compare
BWI76_RS09660 -4.2 -2.9 DNA translocase FtsK compare
BWI76_RS08535 -4.2 -4.0 translocation protein TolB compare
BWI76_RS08520 -4.1 -4.3 colicin transporter TolQ compare
BWI76_RS01610 -4.1 -9.2 phosphoribosylamine--glycine ligase compare
BWI76_RS11845 -4.1 -3.5 tryptophan synthase subunit beta compare
BWI76_RS20355 -4.1 -3.2 colicin V production protein compare
BWI76_RS08530 -4.0 -2.4 protein TolA compare
BWI76_RS20965 -4.0 -5.3 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS23230 -3.9 -4.6 exodeoxyribonuclease V subunit beta compare
BWI76_RS00345 -3.8 -5.6 protein disulfide oxidoreductase DsbA compare
BWI76_RS04670 -3.8 -8.6 3-isopropylmalate dehydratase large subunit compare
BWI76_RS04685 -3.7 -12.4 putative leucine operon leader peptide compare
BWI76_RS05200 -3.7 -3.6 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS25065 -3.6 -2.6 polyribonucleotide nucleotidyltransferase compare
BWI76_RS11840 -3.6 -6.9 tryptophan synthase subunit alpha compare
BWI76_RS04665 -3.6 -18.0 3-isopropylmalate dehydratase small subunit compare
BWI76_RS23240 -3.6 -4.9 exonuclease V subunit gamma compare
BWI76_RS06530 -3.5 -6.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS04680 -3.3 -11.9 2-isopropylmalate synthase compare
BWI76_RS00990 -3.3 -9.0 ketol-acid reductoisomerase compare
BWI76_RS02530 -3.2 -3.9 tRNA dimethylallyltransferase compare
BWI76_RS06525 -3.2 -5.0 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS23480 -3.2 -13.2 EAL domain-containing protein compare
BWI76_RS17980 -3.1 -5.3 RNA chaperone ProQ compare
BWI76_RS05840 -3.1 -6.3 glutamate 5-kinase compare
BWI76_RS07070 -3.0 -4.8 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS00975 -3.0 -10.4 dihydroxy-acid dehydratase compare
BWI76_RS11850 -3.0 -7.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS27390 -3.0 -2.9 ribonuclease PH compare
BWI76_RS20435 -3.0 -1.4 chorismate synthase compare
BWI76_RS18920 -2.9 -2.1 ATP phosphoribosyltransferase compare
BWI76_RS04675 -2.9 -5.3 3-isopropylmalate dehydrogenase compare
BWI76_RS00835 -2.9 -10.0 phosphoenolpyruvate carboxylase compare
BWI76_RS23265 -2.8 -4.1 hypothetical protein compare
BWI76_RS03010 -2.8 -9.1 ornithine carbamoyltransferase compare
BWI76_RS15825 -2.7 -1.9 hypothetical protein compare
BWI76_RS21370 -2.7 -3.0 ATP-dependent RNA helicase SrmB compare
BWI76_RS09760 -2.5 -3.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS17720 -2.5 -1.8 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS08525 -2.5 -1.4 colicin transporter compare
BWI76_RS16965 -2.5 -4.7 murein lipoprotein compare
BWI76_RS17345 -2.4 -6.8 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS17975 -2.4 -6.8 tail-specific protease compare
BWI76_RS01385 -2.4 -3.5 potassium transporter compare
BWI76_RS09970 -2.4 -6.2 porin OmpA compare
BWI76_RS00785 -2.3 -7.4 cystathionine gamma-synthase compare
BWI76_RS12090 -2.2 -1.3 HNH endonuclease compare
BWI76_RS07065 -2.2 -8.6 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS22765 -2.2 -8.2 sulfite reductase subunit alpha compare
BWI76_RS22690 -2.2 -3.6 adenylyl-sulfate kinase compare
BWI76_RS22805 -2.1 -9.8 GTP diphosphokinase compare
BWI76_RS06765 -2.1 -3.5 transcriptional regulator compare
BWI76_RS00960 -2.1 -4.1 acetolactate synthase 2 catalytic subunit compare
BWI76_RS22755 -2.1 -6.1 phosphoadenosine phosphosulfate reductase compare
BWI76_RS17735 -2.0 -2.9 D-amino acid dehydrogenase small subunit compare
BWI76_RS25070 -2.0 -1.8 hypothetical protein compare
BWI76_RS19845 -2.0 -3.6 phosphatase compare
BWI76_RS18630 -2.0 -5.4 nitrogen assimilation transcriptional regulator compare
BWI76_RS16235 -2.0 -3.1 membrane protein compare
BWI76_RS07185 -2.0 -2.3 hypothetical protein compare
BWI76_RS26055 -2.0 -7.5 siroheme synthase compare
BWI76_RS15835 -1.9 -1.4 hypothetical protein compare
BWI76_RS12145 -1.9 -2.5 hypothetical protein compare
BWI76_RS04255 -1.9 -6.7 threonine synthase compare
BWI76_RS05120 -1.9 -7.4 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS20640 -1.8 -2.7 cysteine synthase A compare
BWI76_RS24340 -1.8 -4.9 two-component sensor histidine kinase compare
BWI76_RS25960 -1.8 -3.7 NUDIX hydrolase compare
BWI76_RS04645 -1.8 -4.3 3-dehydroquinase compare
BWI76_RS22760 -1.8 -4.9 sulfite reductase subunit beta compare
BWI76_RS26390 -1.7 -5.3 cell division protein FtsX compare
BWI76_RS00805 -1.7 -5.4 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS21310 -1.7 -1.3 DNA repair protein RecO compare
BWI76_RS20695 -1.7 -3.9 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS05975 -1.7 -4.0 ABC transporter ATP-binding protein compare
BWI76_RS11860 -1.7 -6.2 anthranilate synthase component I compare
BWI76_RS14415 -1.6 -2.1 transcriptional regulator, TetR family protein compare
BWI76_RS20205 -1.6 -4.2 aminotransferase AlaT compare
BWI76_RS18710 -1.6 -9.1 GGDEF-domain containing protein compare
BWI76_RS12985 -1.6 -1.9 transcriptional regulator compare
BWI76_RS20490 -1.6 -3.0 hypothetical protein compare
BWI76_RS23970 -1.6 -2.4 mechanosensitive ion channel protein MscS compare
BWI76_RS13250 -1.6 -1.5 cytochrome b561 compare
BWI76_RS26455 -1.5 -3.6 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS05995 -1.5 -6.6 branched-chain amino acid ABC transporter substrate-binding protein compare
BWI76_RS26830 -1.5 -4.6 endoglucanase compare
BWI76_RS15990 -1.5 -6.1 serine protease compare
BWI76_RS24285 -1.5 -7.9 cystathionine beta-lyase compare
BWI76_RS26460 -1.5 -4.6 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS20650 -1.5 -2.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS16485 -1.4 -2.0 ribonuclease T compare
BWI76_RS04305 -1.4 -1.3 molecular chaperone DnaJ compare
BWI76_RS02545 -1.4 -6.5 protease modulator HflK compare
BWI76_RS14320 -1.4 -1.4 hypothetical protein compare
BWI76_RS11855 -1.3 -3.1 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS06535 -1.3 -5.5 endopeptidase La compare
BWI76_RS02550 -1.3 -6.6 protease modulator HflC compare
BWI76_RS11700 -1.3 -1.5 hypothetical protein compare
BWI76_RS11980 -1.3 -1.0 DeoR family transcriptional regulator compare
BWI76_RS18955 -1.3 -1.8 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS21450 -1.3 -2.6 23S rRNA pseudouridine(1911/1915/1917) synthase compare
BWI76_RS15810 -1.3 -5.6 hypothetical protein compare
BWI76_RS14435 -1.3 -1.0 glutamine ABC transporter ATP-binding protein compare
BWI76_RS01655 -1.3 -5.6 homoserine O-succinyltransferase compare
BWI76_RS00875 -1.3 -5.3 DNA-binding transcriptional regulator FabR compare
BWI76_RS18580 -1.2 -1.8 hypothetical protein compare
BWI76_RS17045 -1.2 -1.6 hypothetical protein compare
BWI76_RS19010 -1.2 -2.5 polysaccharide pyruvyl transferase yvff compare
BWI76_RS15840 -1.2 -2.3 prophage protein compare
BWI76_RS09455 -1.2 -2.5 YbjN domain-containing protein compare
BWI76_RS25060 -1.2 -1.8 lipoprotein NlpI compare
BWI76_RS24080 -1.2 -1.6 DUF179 domain-containing protein compare
BWI76_RS18770 -1.2 -1.1 DNA gyrase inhibitor compare
BWI76_RS26395 -1.2 -2.3 cell division protein FtsE compare
BWI76_RS04250 -1.2 -4.8 homoserine kinase compare
BWI76_RS18240 -1.2 -1.8 L-arabinose ABC transporter permease AraH compare
BWI76_RS19840 -1.2 -1.2 hypothetical protein compare
BWI76_RS05980 -1.2 -5.6 ABC transporter ATP-binding protein compare
BWI76_RS03040 -1.2 -2.4 leucyl aminopeptidase compare
BWI76_RS06770 -1.1 -6.1 Hha toxicity attenuator compare
BWI76_RS24240 -1.1 -1.8 hypothetical protein compare
BWI76_RS11430 -1.1 -1.2 lipoprotein compare
BWI76_RS13595 -1.1 -2.8 transcriptional regulator compare
BWI76_RS25160 -1.1 -1.9 transcription elongation factor GreA compare
BWI76_RS04270 -1.1 -3.5 transaldolase compare
BWI76_RS18715 -1.1 -4.6 hypothetical protein compare
BWI76_RS21475 -1.1 -5.0 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS26045 -1.1 -2.1 nitrite reductase small subunit compare
BWI76_RS20360 -1.1 -1.1 cell division protein DedD compare
BWI76_RS08925 -1.1 -4.0 DNA-binding protein YbiB compare
BWI76_RS21980 -1.1 -2.4 hypothetical protein compare
BWI76_RS14650 -1.0 -2.1 helix-turn-helix transcriptional regulator compare
BWI76_RS20380 -1.0 -1.2 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS01205 -1.0 -1.8 DUF484 family protein compare
BWI76_RS21710 -1.0 -3.1 nitroreductase compare
BWI76_RS03920 -1.0 -2.4 N-acetyltransferase compare
BWI76_RS27425 -1.0 -1.2 DNA-directed RNA polymerase subunit omega compare
BWI76_RS11900 -1.0 -1.2 cob(I)yrinic acid a,c-diamide adenosyltransferase compare
BWI76_RS12450 -1.0 -3.0 phage shock protein PspA compare
BWI76_RS05990 -1.0 -4.6 branched-chain amino acid ABC transporter permease compare
BWI76_RS19870 -1.0 -1.8 malate:quinone oxidoreductase compare
BWI76_RS16895 -1.0 -1.3 3-(3-hydroxy-phenyl)propionate transporter MhpT compare
BWI76_RS21465 -1.0 -2.7 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS25910 -1.0 -2.2 peptidyl-prolyl cis-trans isomerase compare
BWI76_RS25280 -1.0 -1.5 RNase adaptor protein RapZ compare
BWI76_RS26470 -1.0 -4.2 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS02410 -1.0 -1.4 EF-P beta-lysylation protein EpmB compare
BWI76_RS17290 -1.0 -3.7 formyltetrahydrofolate deformylase compare
BWI76_RS07645 -1.0 -1.7 short-chain dehydrogenase/reductase compare
BWI76_RS12335 -1.0 -3.8 hypothetical protein compare
BWI76_RS27940 -1.0 -2.2 2-dehydro-3-deoxy-6-phosphogalactonate aldolase compare
BWI76_RS14170 -1.0 -1.5 hypothetical protein compare
BWI76_RS19035 -1.0 -3.7 dTDP-rhamnosyl transferase compare
BWI76_RS17110 -1.0 -1.4 vitamin B12 ABC transporter permease BtuC compare
BWI76_RS26570 -0.9 -1.7 anion permease compare
BWI76_RS08705 -0.9 -3.0 putative LuxR family regulatory protein compare
BWI76_RS21375 -0.9 -1.5 autonomous glycyl radical cofactor GrcA compare
BWI76_RS22700 -0.9 -2.0 sulfate adenylyltransferase subunit 2 compare
BWI76_RS19495 -0.9 -1.0 ABC transporter, quaternary amine uptake transporter (QAT) family, ATP-binding protein compare
BWI76_RS14050 -0.9 -1.8 AP endonuclease, family 2 compare
BWI76_RS03660 -0.9 -2.1 hypothetical protein compare
BWI76_RS01350 -0.9 -0.8 NAD(P)H-flavin reductase compare
BWI76_RS00850 -0.9 -4.4 acetylglutamate kinase compare
BWI76_RS11515 -0.9 -1.2 peptide-methionine (R)-S-oxide reductase compare
BWI76_RS27435 -0.9 -3.5 tRNA (guanosine(18)-2'-O)-methyltransferase TrmH compare
BWI76_RS26665 -0.9 -1.3 DNA-binding response regulator compare


Specific Phenotypes

For 4 genes in this experiment

For nitrogen source L-Isoleucine in Klebsiella michiganensis M5al

For nitrogen source L-Isoleucine across organisms