Experiment set6IT014 for Klebsiella michiganensis M5al

Compare to:

L-Valine nitrogen source

200 most important genes:

  gene name fitness t score description  
BWI76_RS18920 -7.4 -5.1 ATP phosphoribosyltransferase compare
BWI76_RS11965 -7.1 -5.9 orotidine-5'-phosphate decarboxylase compare
BWI76_RS18925 -6.9 -8.2 histidinol dehydrogenase compare
BWI76_RS00855 -6.9 -9.5 argininosuccinate lyase compare
BWI76_RS20895 -6.6 -6.4 phosphoribosylaminoimidazolesuccinocarboxamide synthase compare
BWI76_RS04160 -6.5 -6.2 phosphoserine phosphatase compare
BWI76_RS00960 -6.2 -8.5 acetolactate synthase 2 catalytic subunit compare
BWI76_RS00990 -5.9 -10.0 ketol-acid reductoisomerase compare
BWI76_RS05840 -5.9 -7.0 glutamate 5-kinase compare
BWI76_RS04470 -5.9 -12.0 carbamoyl phosphate synthase large subunit compare
BWI76_RS20350 -5.7 -5.6 amidophosphoribosyltransferase compare
BWI76_RS18940 -5.6 -7.4 imidazole glycerol phosphate synthase subunit HisH compare
BWI76_RS00390 -5.6 -7.6 two-component system sensor histidine kinase NtrB compare
BWI76_RS20965 -5.6 -4.5 phosphoribosylformylglycinamidine cyclo-ligase compare
BWI76_RS27385 -5.6 -8.3 orotate phosphoribosyltransferase compare
BWI76_RS23920 -5.3 -6.0 D-3-phosphoglycerate dehydrogenase compare
BWI76_RS09755 -5.3 -9.2 phosphoserine transaminase compare
BWI76_RS09645 -5.3 -1.9 thioredoxin-disulfide reductase compare
BWI76_RS25115 -5.3 -9.0 argininosuccinate synthase compare
BWI76_RS04465 -5.2 -7.9 carbamoyl-phosphate synthase small subunit compare
BWI76_RS09910 -5.1 -18.4 dihydroorotate dehydrogenase (quinone) compare
BWI76_RS01610 -5.1 -10.5 phosphoribosylamine--glycine ligase compare
BWI76_RS01615 -5.0 -10.1 bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/inosine monophosphate cyclohydrolase compare
BWI76_RS11850 -5.0 -6.9 bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase compare
BWI76_RS02995 -5.0 -9.4 aspartate carbamoyltransferase compare
BWI76_RS11840 -5.0 -6.0 tryptophan synthase subunit alpha compare
BWI76_RS04675 -5.0 -5.4 3-isopropylmalate dehydrogenase compare
BWI76_RS21265 -4.9 -13.0 phosphoribosylformylglycinamidine synthase compare
BWI76_RS05015 -4.9 -4.0 transcriptional regulator compare
BWI76_RS18950 -4.9 -5.4 imidazole glycerol phosphate synthase cyclase subunit compare
BWI76_RS18935 -4.9 -8.1 bifunctional imidazole glycerol-phosphate dehydratase/histidinol phosphatase compare
BWI76_RS10990 -4.8 -4.1 dihydroorotase compare
BWI76_RS08385 -4.7 -5.3 citrate (Si)-synthase compare
BWI76_RS00385 -4.7 -10.0 nitrogen assimilation regulatory protein compare
BWI76_RS07070 -4.6 -8.2 5-(carboxyamino)imidazole ribonucleotide mutase compare
BWI76_RS23230 -4.6 -3.1 exodeoxyribonuclease V subunit beta compare
BWI76_RS04670 -4.5 -10.1 3-isopropylmalate dehydratase large subunit compare
BWI76_RS05200 -4.4 -3.0 bifunctional uridylyltransferase/uridylyl-removing protein compare
BWI76_RS11845 -4.2 -3.6 tryptophan synthase subunit beta compare
BWI76_RS20355 -4.1 -3.7 colicin V production protein compare
BWI76_RS00975 -4.1 -8.1 dihydroxy-acid dehydratase compare
BWI76_RS04665 -4.0 -17.2 3-isopropylmalate dehydratase small subunit compare
BWI76_RS03010 -4.0 -8.4 ornithine carbamoyltransferase compare
BWI76_RS08180 -4.0 -7.5 asparagine synthase B compare
BWI76_RS05835 -4.0 -4.3 gamma-glutamyl-phosphate reductase compare
BWI76_RS23360 -3.9 -3.2 diaminopimelate decarboxylase compare
BWI76_RS00980 -3.9 -9.9 PLP-dependent threonine dehydratase compare
BWI76_RS08525 -3.9 -5.6 colicin transporter compare
BWI76_RS17720 -3.8 -2.0 muramoyltetrapeptide carboxypeptidase compare
BWI76_RS18930 -3.8 -5.9 histidinol-phosphate transaminase compare
BWI76_RS04685 -3.8 -11.2 putative leucine operon leader peptide compare
BWI76_RS23240 -3.8 -5.1 exonuclease V subunit gamma compare
BWI76_RS26085 -3.8 -3.1 3-dehydroquinate synthase compare
BWI76_RS00835 -3.7 -13.7 phosphoenolpyruvate carboxylase compare
BWI76_RS04255 -3.7 -13.7 threonine synthase compare
BWI76_RS00400 -3.7 -2.3 glutamine synthetase compare
BWI76_RS11860 -3.6 -5.9 anthranilate synthase component I compare
BWI76_RS04680 -3.5 -8.0 2-isopropylmalate synthase compare
BWI76_RS21465 -3.5 -3.6 bifunctional chorismate mutase/prephenate dehydratase compare
BWI76_RS23480 -3.5 -14.9 EAL domain-containing protein compare
BWI76_RS09660 -3.4 -3.3 DNA translocase FtsK compare
BWI76_RS22755 -3.4 -7.0 phosphoadenosine phosphosulfate reductase compare
BWI76_RS04645 -3.4 -7.3 3-dehydroquinase compare
BWI76_RS02530 -3.4 -4.6 tRNA dimethylallyltransferase compare
BWI76_RS07065 -3.3 -10.1 5-(carboxyamino)imidazole ribonucleotide synthase compare
BWI76_RS11855 -3.3 -5.3 bifunctional glutamine amidotransferase/anthranilate phosphoribosyltransferase compare
BWI76_RS27430 -3.2 -1.6 (p)ppGpp synthetase compare
BWI76_RS00970 -3.2 -4.5 branched chain amino acid aminotransferase compare
BWI76_RS09760 -3.1 -7.9 3-phosphoshikimate 1-carboxyvinyltransferase compare
BWI76_RS01210 -3.1 -4.2 tyrosine recombinase XerC compare
BWI76_RS04245 -2.9 -11.6 bifunctional aspartate kinase/homoserine dehydrogenase I compare
BWI76_RS08535 -2.8 -3.2 translocation protein TolB compare
BWI76_RS04240 -2.8 -3.8 thr operon leader peptide compare
BWI76_RS22760 -2.8 -6.2 sulfite reductase subunit beta compare
BWI76_RS00850 -2.8 -11.0 acetylglutamate kinase compare
BWI76_RS08530 -2.8 -2.3 protein TolA compare
BWI76_RS22805 -2.8 -11.7 GTP diphosphokinase compare
BWI76_RS00345 -2.8 -5.2 protein disulfide oxidoreductase DsbA compare
BWI76_RS08520 -2.8 -3.2 colicin transporter TolQ compare
BWI76_RS10835 -2.7 -2.2 hypothetical protein compare
BWI76_RS17735 -2.6 -6.1 D-amino acid dehydrogenase small subunit compare
BWI76_RS17980 -2.6 -7.3 RNA chaperone ProQ compare
BWI76_RS22765 -2.6 -9.4 sulfite reductase subunit alpha compare
BWI76_RS27390 -2.6 -3.1 ribonuclease PH compare
BWI76_RS04250 -2.6 -7.2 homoserine kinase compare
BWI76_RS20640 -2.5 -4.6 cysteine synthase A compare
BWI76_RS17975 -2.5 -8.1 tail-specific protease compare
BWI76_RS21370 -2.4 -3.2 ATP-dependent RNA helicase SrmB compare
BWI76_RS06530 -2.4 -6.4 ATP-dependent Clp protease ATP-binding subunit ClpX compare
BWI76_RS14415 -2.3 -3.1 transcriptional regulator, TetR family protein compare
BWI76_RS00845 -2.2 -7.5 N-acetyl-gamma-glutamyl-phosphate reductase compare
BWI76_RS24285 -2.2 -7.6 cystathionine beta-lyase compare
BWI76_RS00785 -2.2 -4.1 cystathionine gamma-synthase compare
BWI76_RS20650 -2.2 -3.2 phosphoenolpyruvate--protein phosphotransferase compare
BWI76_RS26055 -2.1 -6.6 siroheme synthase compare
BWI76_RS27440 -2.1 -3.1 DNA helicase RecG compare
BWI76_RS16965 -2.1 -6.1 murein lipoprotein compare
BWI76_RS26455 -2.1 -3.7 4-amino-4-deoxy-L-arabinose-phospho-UDP flippase compare
BWI76_RS09970 -2.0 -6.3 porin OmpA compare
BWI76_RS02725 -2.0 -1.6 HxlR family transcriptional regulator compare
BWI76_RS20360 -2.0 -1.6 cell division protein DedD compare
BWI76_RS01350 -1.9 -1.4 NAD(P)H-flavin reductase compare
BWI76_RS23265 -1.9 -3.2 hypothetical protein compare
BWI76_RS23220 -1.9 -7.8 amino-acid N-acetyltransferase compare
BWI76_RS05120 -1.8 -8.8 bifunctional glycosyl transferase/transpeptidase compare
BWI76_RS16235 -1.8 -4.2 membrane protein compare
BWI76_RS25280 -1.8 -2.2 RNase adaptor protein RapZ compare
BWI76_RS22690 -1.8 -2.7 adenylyl-sulfate kinase compare
BWI76_RS02735 -1.7 -4.3 3'(2'),5'-bisphosphate nucleotidase CysQ compare
BWI76_RS00965 -1.7 -1.5 acetolactate synthase 2 small subunit compare
BWI76_RS21475 -1.7 -5.1 bifunctional chorismate mutase/prephenate dehydrogenase compare
BWI76_RS25960 -1.7 -4.0 NUDIX hydrolase compare
BWI76_RS18955 -1.7 -3.1 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase compare
BWI76_RS06535 -1.7 -4.5 endopeptidase La compare
BWI76_RS11700 -1.6 -1.8 hypothetical protein compare
BWI76_RS20705 -1.6 -3.5 thiosulfate transporter subunit compare
BWI76_RS24080 -1.5 -1.2 DUF179 domain-containing protein compare
BWI76_RS15850 -1.5 -2.1 DUF1317 domain-containing protein compare
BWI76_RS23365 -1.5 -3.0 LysR family transcriptional regulator compare
BWI76_RS12090 -1.5 -1.3 HNH endonuclease compare
BWI76_RS20380 -1.5 -1.6 tRNA pseudouridine(38-40) synthase TruA compare
BWI76_RS06525 -1.5 -5.4 ATP-dependent Clp protease proteolytic subunit compare
BWI76_RS25060 -1.5 -2.8 lipoprotein NlpI compare
BWI76_RS20495 -1.4 -9.4 alanine transaminase conserved
BWI76_RS13095 -1.4 -2.3 phenylacetate-CoA oxygenase subunit PaaB compare
BWI76_RS25645 -1.4 -5.1 shikimate dehydrogenase compare
BWI76_RS00805 -1.4 -3.9 5,10-methylenetetrahydrofolate reductase compare
BWI76_RS13010 -1.4 -4.0 LysR family transcriptional regulator compare
BWI76_RS15215 -1.4 -1.4 N-acetyltransferase compare
BWI76_RS05450 -1.4 -1.8 ribonuclease HI compare
BWI76_RS25070 -1.4 -1.5 hypothetical protein compare
BWI76_RS15835 -1.3 -0.9 hypothetical protein compare
BWI76_RS19870 -1.3 -2.6 malate:quinone oxidoreductase compare
BWI76_RS18770 -1.3 -1.2 DNA gyrase inhibitor compare
BWI76_RS15840 -1.3 -2.8 prophage protein compare
BWI76_RS24235 -1.3 -4.4 Branched-chain-amino-acid transaminase (EC 2.6.1.42) (from data) compare
BWI76_RS26460 -1.3 -4.7 4-amino-4-deoxy-L-arabinose-phosphoundecaprenol flippase subunit ArnE compare
BWI76_RS00875 -1.3 -5.2 DNA-binding transcriptional regulator FabR compare
BWI76_RS15990 -1.3 -4.0 serine protease compare
BWI76_RS26775 -1.3 -3.8 endo-1,4-D-glucanase compare
BWI76_RS21350 -1.2 -3.9 anti-RNA polymerase sigma factor SigE compare
BWI76_RS18630 -1.2 -4.2 nitrogen assimilation transcriptional regulator compare
BWI76_RS26390 -1.2 -4.2 cell division protein FtsX compare
BWI76_RS20695 -1.2 -2.4 sulfate/thiosulfate transporter permease subunit compare
BWI76_RS15830 -1.2 -1.9 hypothetical protein compare
BWI76_RS02545 -1.2 -5.8 protease modulator HflK compare
BWI76_RS13005 -1.2 -7.0 thiamine pyrophosphate protein TPP-binding protein compare
BWI76_RS06765 -1.2 -2.4 transcriptional regulator compare
BWI76_RS18165 -1.2 -1.5 NUDIX pyrophosphatase compare
BWI76_RS25600 -1.2 -1.2 tRNA-Thr compare
BWI76_RS05005 -1.2 -2.4 polynucleotide adenylyltransferase compare
BWI76_RS24240 -1.2 -1.9 hypothetical protein compare
BWI76_RS20490 -1.2 -2.0 hypothetical protein compare
BWI76_RS20435 -1.2 -0.6 chorismate synthase compare
BWI76_RS15825 -1.2 -1.2 hypothetical protein compare
BWI76_RS25065 -1.2 -2.4 polyribonucleotide nucleotidyltransferase compare
BWI76_RS20690 -1.2 -2.7 sulfate ABC transporter ATP-binding protein compare
BWI76_RS20880 -1.2 -2.3 esterase compare
BWI76_RS13595 -1.2 -2.9 transcriptional regulator compare
BWI76_RS01655 -1.1 -5.0 homoserine O-succinyltransferase compare
BWI76_RS21070 -1.1 -1.6 outer membrane protein assembly factor BamB compare
BWI76_RS15810 -1.1 -3.2 hypothetical protein compare
BWI76_RS00430 -1.1 -3.7 GNAT family N-acetyltransferase compare
BWI76_RS26395 -1.1 -3.5 cell division protein FtsE compare
BWI76_RS13445 -1.1 -1.8 alpha/beta hydrolase compare
BWI76_RS09335 -1.1 -1.4 baseplate assembly protein W compare
BWI76_RS20700 -1.1 -5.4 sulfate/thiosulfate transporter subunit compare
BWI76_RS07645 -1.1 -1.6 short-chain dehydrogenase/reductase compare
BWI76_RS26570 -1.1 -2.7 anion permease compare
BWI76_RS14375 -1.1 -2.8 hypothetical protein compare
BWI76_RS14915 -1.1 -1.8 hypothetical protein compare
BWI76_RS22695 -1.1 -4.3 sulfate adenylyltransferase compare
BWI76_RS13755 -1.1 -1.8 hypothetical protein compare
BWI76_RS15635 -1.1 -3.3 hypothetical protein compare
BWI76_RS26470 -1.0 -3.9 4-deoxy-4-formamido-L-arabinose- phosphoundecaprenol deformylase compare
BWI76_RS14390 -1.0 -1.5 hypothetical protein compare
BWI76_RS17345 -1.0 -2.9 nitrate/nitrite two-component system sensor histidine kinase NarX compare
BWI76_RS18070 -1.0 -1.7 DNA polymerase III subunit epsilon compare
BWI76_RS04270 -1.0 -4.3 transaldolase compare
BWI76_RS04530 -1.0 -1.8 peptidylprolyl isomerase SurA compare
BWI76_RS08705 -1.0 -2.6 putative LuxR family regulatory protein compare
BWI76_RS20440 -1.0 -3.3 50S ribosomal protein L3 N(5)-glutamine methyltransferase compare
BWI76_RS06395 -1.0 -3.2 tRNA 4-thiouridine(8) synthase ThiI compare
BWI76_RS09030 -1.0 -6.0 transpeptidase compare
BWI76_RS14320 -1.0 -2.1 hypothetical protein compare
BWI76_RS10770 -1.0 -3.1 pyrimidine utilization protein C compare
BWI76_RS05445 -1.0 -3.7 type 11 methyltransferase compare
BWI76_RS09255 -1.0 -1.2 hypothetical protein compare
BWI76_RS24340 -1.0 -5.0 two-component sensor histidine kinase compare
BWI76_RS24485 -1.0 -1.8 bifunctional dihydroneopterin aldolase/7,8-dihydroneopterin epimerase compare
BWI76_RS11285 -1.0 -1.5 transcriptional regulator compare
BWI76_RS14625 -0.9 -1.1 protein TolA compare
BWI76_RS19375 -0.9 -1.6 bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase compare
BWI76_RS07985 -0.9 -1.0 fluoride ion transporter CrcB compare
BWI76_RS00840 -0.9 -4.4 acetylornithine deacetylase compare
BWI76_RS00180 -0.9 -1.2 F0F1 ATP synthase subunit epsilon compare
BWI76_RS02550 -0.9 -3.4 protease modulator HflC compare
BWI76_RS13590 -0.9 -2.0 hypothetical protein compare
BWI76_RS15770 -0.9 -3.6 hypothetical protein compare
BWI76_RS09960 -0.9 -2.4 Lon protease compare


Specific Phenotypes

For 3 genes in this experiment

For nitrogen source L-Valine in Klebsiella michiganensis M5al

For nitrogen source L-Valine across organisms