Experiment set6IT013 for Methanococcus maripaludis S2

200 most detrimental genes:

gene	name	fitness	t score	description
MMP_RS08370		+1.8	2.1	cation:proton antiporter subunit C
MMP_RS01370		+1.4	10.5	acetate--CoA ligase family protein
MMP_RS01775		+1.1	3.3	TIGR00297 family protein
MMP_RS06575		+0.9	4.2	fluoride efflux transporter CrcB
MMP_RS00325		+0.9	2.4	RNA-binding protein
MMP_RS07125		+0.9	3.5	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS02790		+0.8	1.5	class III signal peptide-containing protein
MMP_RS00395		+0.7	1.9	MGMT family protein
MMP_RS00825		+0.7	3.2	fumarylacetoacetate hydrolase family protein
MMP_RS07815		+0.7	1.4	DUF2120 domain-containing protein
MMP_RS02310		+0.6	1.7	RimK-like ATPgrasp N-terminal domain-containing protein
MMP_RS07890		+0.6	2.2	OB-fold nucleic acid binding domain-containing protein
MMP_RS08275		+0.6	4.3	hypothetical protein
MMP_RS08995		+0.6	1.2	hypothetical protein
MMP_RS00185		+0.6	4.5	potassium channel protein
MMP_RS07850		+0.5	1.6	prephenate dehydratase
MMP_RS06555		+0.5	2.5	cupin domain-containing protein
MMP_RS07130		+0.5	3.6	coenzyme F420 hydrogenase subunit gamma
MMP_RS01540		+0.5	1.5	DUF504 domain-containing protein
MMP_RS06540		+0.5	1.7	3-methyl-2-oxobutanoate dehydrogenase subunit VorB
MMP_RS07415		+0.5	3.9	molybdopterin-guanine dinucleotide biosynthesis protein MobB
MMP_RS05835		+0.5	0.7	secondary thiamine-phosphate synthase enzyme YjbQ
MMP_RS07620		+0.5	2.2	energy-coupling factor ABC transporter substrate-binding protein
MMP_RS06325		+0.5	1.2	hypothetical protein
MMP_RS07120		+0.5	3.8	coenzyme F420 hydrogenase subunit alpha
MMP_RS06435		+0.5	2.7	CBS domain-containing protein
MMP_RS08365		+0.5	2.3	energy conserving hydrogenase EhbF
MMP_RS08265		+0.5	2.5	rubrerythrin
MMP_RS01100		+0.5	1.3	ABC transporter ATP-binding protein
MMP_RS07115		+0.5	2.5	MBL fold metallo-hydrolase
MMP_RS00725		+0.5	2.8	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdC
MMP_RS04520		+0.5	2.7	nucleoside deaminase
MMP_RS03215		+0.5	3.6	MBL fold metallo-hydrolase
MMP_RS05535		+0.5	2.1	hypothetical protein
MMP_RS00740		+0.5	1.4	cyclase family protein
MMP_RS00735		+0.5	1.3	5 10-methenyltetrahydromethanopterin hydrogenase
MMP_RS06155		+0.5	1.4	DUF4186 domain-containing protein
MMP_RS02495		+0.4	1.4	hypothetical protein
MMP_RS03390		+0.4	2.5	malate dehydrogenase
MMP_RS08335		+0.4	1.9	NADH-quinone oxidoreductase subunit B family protein
MMP_RS02835		+0.4	2.4	CGGC domain-containing protein
MMP_RS07335		+0.4	2.0	tRNA (cytidine(56)-2'-O)-methyltransferase
MMP_RS05970		+0.4	1.3	class II SORL domain-containing protein
MMP_RS00730		+0.4	2.6	5 10-methenyltetrahydromethanopterin hydrogenase cofactor biosynthesis protein HmdB
MMP_RS06535		+0.4	2.1	2-oxoacid:acceptor oxidoreductase family protein
MMP_RS01650		+0.4	0.7	sulfurtransferase TusA family protein
MMP_RS05265		+0.4	0.9	2-isopropylmalate synthase
MMP_RS07925		+0.4	1.2	haloacid dehalogenase
MMP_RS05525		+0.4	2.2	calcium/sodium antiporter
MMP_RS08595		+0.4	0.6	flagellar protein C
MMP_RS06860		+0.4	1.2	4Fe-4S binding protein
MMP_RS07725		+0.4	1.7	4Fe-4S dicluster domain-containing protein
MMP_RS01430		+0.4	2.5	mechanosensitive ion channel family protein
MMP_RS02595		+0.4	0.9	putative zinc-binding protein
MMP_RS00665		+0.4	1.9	hypothetical protein
MMP_RS03965		+0.4	1.4	hypothetical protein
MMP_RS08455		+0.4	1.6	multiprotein bridging factor aMBF1
MMP_RS07700		+0.4	2.9	DUF1188 domain-containing protein
MMP_RS08310		+0.4	1.2	TMEM165/GDT1 family protein
MMP_RS07695		+0.4	2.7	DUF3236 domain-containing protein
MMP_RS01580		+0.4	2.7	PQQ-binding-like beta-propeller repeat protein
MMP_RS08555		+0.4	1.8	hypothetical protein
MMP_RS01115		+0.4	2.4	molybdopterin molybdotransferase MoeA
MMP_RS00530		+0.4	2.5	tRNA pseudouridine(54/55) synthase Pus10
MMP_RS06485		+0.4	0.6	zinc ribbon domain-containing protein
MMP_RS01525		+0.4	1.0	nucleoside-diphosphate kinase
MMP_RS03535		+0.4	1.7	helix-turn-helix transcriptional regulator
MMP_RS06965		+0.4	2.0	TIGR04014 family B12-binding domain/radical SAM domain-containing protein
MMP_RS06570		+0.4	1.1	DUF190 domain-containing protein
MMP_RS08345		+0.4	2.3	4Fe-4S binding protein
MMP_RS07135		+0.4	2.5	coenzyme F420 hydrogenase subunit beta
MMP_RS03245		+0.4	2.0	DNA repair and recombination protein RadB
MMP_RS05455		+0.3	2.2	DUF167 domain-containing protein
MMP_RS02805		+0.3	0.6	HEPN domain-containing protein
MMP_RS08215		+0.3	1.0	DUF483 domain-containing protein
MMP_RS08340		+0.3	1.8	4Fe-4S binding protein
MMP_RS02545		+0.3	1.3	hypothetical protein
MMP_RS01620		+0.3	1.0	hypothetical protein
MMP_RS07095		+0.3	1.6	PspC domain-containing protein
MMP_RS07900		+0.3	0.6	YeeE/YedE family protein
MMP_RS08605		+0.3	1.7	flagellar protein E
MMP_RS06550		+0.3	2.0	AMP-binding protein
MMP_RS06300		+0.3	2.3	ABC transporter substrate-binding protein
MMP_RS00315		+0.3	2.0	Nif3-like dinuclear metal center hexameric protein
MMP_RS02290		+0.3	1.7	MBL fold metallo-hydrolase
MMP_RS05950		+0.3	1.8	nickel-dependent hydrogenase large subunit
MMP_RS00635		+0.3	1.6	energy-coupling factor transporter transmembrane protein EcfT
MMP_RS08355		+0.3	1.9	Na(+)/H(+) antiporter subunit B
MMP_RS08705		+0.3	1.7	sulfopyruvate decarboxylase subunit beta
MMP_RS08640		+0.3	2.1	TIM barrel protein
MMP_RS02645		+0.3	1.6	ArsR family transcriptional regulator
MMP_RS05990		+0.3	1.3	DsrE family protein
MMP_RS01125		+0.3	1.5	thioredoxin family protein
MMP_RS07835		+0.3	1.3	TldD/PmbA family protein
MMP_RS01635		+0.3	1.6	thiamine pyrophosphate-dependent enzyme
MMP_RS05930		+0.3	1.0	3-isopropylmalate dehydratase large subunit
MMP_RS08470		+0.3	1.7	ATP-binding cassette domain-containing protein
MMP_RS01685		+0.3	1.2	indolepyruvate oxidoreductase subunit beta
MMP_RS00105		+0.3	1.7	hypothetical protein
MMP_RS02490		+0.3	1.6	hypothetical protein
MMP_RS08760		+0.3	0.4	hypothetical protein
MMP_RS04985		+0.3	1.8	DUF2180 family protein
MMP_RS00940		+0.3	1.6	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein
MMP_RS06530		+0.3	1.6	bifunctional hexulose-6-phosphate synthase/ribonuclease regulator
MMP_RS08835		+0.3	1.7	H(2)-dependent methylenetetrahydromethanopterin dehydrogenase-related protein
MMP_RS00930		+0.3	1.6	ABC transporter permease
MMP_RS04265		+0.3	1.3	coenzyme F420-reducing hydrogenase FrhD protein
MMP_RS05175		+0.3	1.6	hypothetical protein
MMP_RS02110		+0.3	0.4	hypothetical protein
MMP_RS08390		+0.3	1.5	DUF5400 domain-containing protein
MMP_RS05960		+0.3	1.9	CoB--CoM heterodisulfide reductase subunit B
MMP_RS07595		+0.3	2.1	hypothetical protein
MMP_RS04100		+0.3	1.1	hypothetical protein
MMP_RS01130		+0.3	1.4	flavoprotein
MMP_RS02785		+0.2	1.5	MarR family transcriptional regulator
MMP_RS07840		+0.2	1.0	ribonuclease III
MMP_RS00085		+0.2	1.8	DNA cytosine methyltransferase
MMP_RS01415		+0.2	0.9	DUF2067 domain-containing protein
MMP_RS06290		+0.2	1.1	DNA repair and recombination protein RadA
MMP_RS04850		+0.2	2.2	UPF0254 family protein
MMP_RS01930		+0.2	2.0	hypothetical protein
MMP_RS05975		+0.2	0.6	hypothetical protein
MMP_RS01030		+0.2	1.5	MTAP family purine nucleoside phosphorylase
MMP_RS08485		+0.2	1.7	tungstate ABC transporter substrate-binding protein WtpA
MMP_RS00655		+0.2	1.0	hypothetical protein
MMP_RS02895		+0.2	1.7	DHH family phosphoesterase
MMP_RS02745		+0.2	0.7	hypothetical protein
MMP_RS00955		+0.2	1.9	coenzyme gamma-F420-2:alpha-L-glutamate ligase
MMP_RS04205		+0.2	1.4	carboxymuconolactone decarboxylase family protein
MMP_RS01675		+0.2	0.6	hypothetical protein
MMP_RS01490		+0.2	1.5	tetratricopeptide repeat protein
MMP_RS00545		+0.2	1.4	XRE family transcriptional regulator
MMP_RS00800		+0.2	1.9	Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
MMP_RS05825		+0.2	1.1	peptidyl-prolyl cis-trans isomerase
MMP_RS01155		+0.2	1.9	XRE family transcriptional regulator
MMP_RS03450		+0.2	0.8	glycine synthesis protein GlyXS (from data)
MMP_RS06150		+0.2	1.6	hypothetical protein
MMP_RS01630		+0.2	1.6	N-glycosylase/DNA lyase
MMP_RS08160		+0.2	1.5	EamA family transporter
MMP_RS05980		+0.2	1.2	ferritin
MMP_RS05660		+0.2	1.4	phosphate ABC transporter substrate-binding protein
MMP_RS08480		+0.2	1.9	molybdate ABC transporter substrate-binding protein
MMP_RS06545		+0.2	1.0	ferredoxin family protein
MMP_RS01300		+0.2	1.9	hypothetical protein
MMP_RS06770		+0.2	1.1	DHH family phosphoesterase
MMP_RS00390		+0.2	1.6	ammonium transporter
MMP_RS08235		+0.2	1.2	hypothetical protein
MMP_RS00375		+0.2	1.5	ammonium transporter
MMP_RS02590		+0.2	1.4	low molecular weight phosphatase family protein
MMP_RS07615		+0.2	1.0	energy-coupling factor ABC transporter permease
MMP_RS02375		+0.2	1.4	hypothetical protein
MMP_RS00750		+0.2	0.4	fumarate hydratase
MMP_RS01655		+0.2	0.6	DsrE family protein
MMP_RS02085		+0.2	1.3	inosine/xanthosine triphosphatase
MMP_RS03405		+0.2	0.9	RNA 3'-terminal phosphate cyclase
MMP_RS07100		+0.2	1.4	hypothetical protein
MMP_RS06250		+0.2	1.3	hypothetical protein
MMP_RS07155		+0.2	1.5	MFS transporter
MMP_RS01455		+0.2	1.3	nickel pincer cofactor biosynthesis protein LarC
MMP_RS07970		+0.2	0.8	hypothetical protein
MMP_RS07140		+0.2	1.6	TIGR00341 family protein
MMP_RS00630		+0.2	1.5	ECF transporter S component
MMP_RS05035		+0.2	1.4	hypothetical protein
MMP_RS08580		+0.2	0.6	flagellin
MMP_RS07895		+0.2	1.1	cytochrome c
MMP_RS02475		+0.2	0.8	hypothetical protein
MMP_RS08155		+0.2	1.2	hypothetical protein
MMP_RS03115		+0.2	1.6	hypothetical protein
MMP_RS01460		+0.2	1.0	hypothetical protein
MMP_RS01435		+0.2	1.1	DMT family transporter
MMP_RS00435		+0.2	1.5	CPBP family intramembrane metalloprotease
MMP_RS08175		+0.2	1.1	7-cyano-7-deazaguanine synthase
MMP_RS00560		+0.2	1.1	cation:proton antiporter
MMP_RS08280		+0.2	0.8	proteasome assembly chaperone family protein
MMP_RS08655		+0.2	1.5	phosphoadenosine phosphosulfate reductase family protein
MMP_RS06585		+0.2	0.5	DMT family protein
MMP_RS00145		+0.2	1.2	ATP-dependent Clp protease proteolytic subunit
MMP_RS00100		+0.2	1.5	tRNA pseudouridine(13) synthase TruD
MMP_RS04970		+0.2	1.5	F420-dependent thioredoxin reductase
MMP_RS00660		+0.2	1.4	alkaline phosphatase family protein
MMP_RS05955		+0.2	0.7	CoB--CoM heterodisulfide reductase subunit C
MMP_RS01260		+0.2	1.0	HDIG domain-containing protein
MMP_RS08090		+0.2	0.9	hypothetical protein
MMP_RS04740		+0.2	1.0	DUF473 domain-containing protein
MMP_RS02690		+0.2	0.9	FmdE family protein
MMP_RS07855		+0.2	1.2	class I SAM-dependent methyltransferase
MMP_RS08260		+0.2	1.1	DUF99 family protein
MMP_RS04325		+0.2	1.2	MtaA/CmuA family methyltransferase
MMP_RS07150		+0.2	1.2	MTH895/ArsE family thioredoxin-like protein
MMP_RS02815		+0.2	0.8	hypothetical protein
MMP_RS05720		+0.2	0.9	signal recognition particle subunit SRP19/SEC65 family protein
MMP_RS06735		+0.2	1.1	class I SAM-dependent rRNA methyltransferase
MMP_RS03615		+0.2	1.4	4Fe-4S binding protein
MMP_RS02685		+0.2	1.1	molybdate ABC transporter substrate-binding protein
MMP_RS03775		+0.2	0.9	4Fe-4S dicluster domain-containing protein
MMP_RS09030		+0.2	1.0	hypothetical protein
MMP_RS08405		+0.2	1.4	MFS transporter
MMP_RS05715		+0.2	1.0	hypothetical protein
MMP_RS03770		+0.2	1.2	hydroxylamine reductase
MMP_RS06600		+0.2	0.2	class III signal peptide-containing protein

Specific Phenotypes

None in this experiment

For Methanococcus maripaludis S2 in nutrient t1 experiments