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Experiment set6IT009 for
Methanococcus maripaludis S2
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formate McAA pyroxidine HCl dropout
200 most important genes:
gene
name
fitness
t score
description
MMP
_RS01175
-5.4
-8.2
triphosphoribosyl-dephospho-CoA synthase
compare
MMP
_RS03315
-4.8
-2.4
ferrous iron transport protein A
compare
MMP
_RS06355
-4.7
-4.7
molybdenum cofactor biosynthesis protein MoaE
compare
MMP
_RS01020
-4.6
-1.9
3 4-dihydroxy-2-butanone-4-phosphate synthase
compare
MMP
_RS06700
-4.4
-14.3
hypothetical protein
compare
MMP
_RS06680
-4.4
-19.1
Coenzyme F420 hydrogenase/dehydrogenase beta subunit C-terminal domain
compare
MMP
_RS03015
-4.3
-17.4
GTP 3' 8-cyclase MoaA
compare
MMP
_RS06685
-4.3
-18.1
formate dehydrogenase H subunit alpha selenocysteine-containing
compare
MMP
_RS06350
-4.2
-10.9
HesA/MoeB/ThiF family protein
compare
MMP
_RS02010
-4.2
-12.5
PHP domain-containing protein
compare
MMP
_RS07635
-4.0
-10.6
MogA/MoaB family molybdenum cofactor biosynthesis protein
compare
MMP
_RS06345
-3.9
-16.5
formate dehydrogenase accessory sulfurtransferase FdhD
compare
MMP
_RS05515
-3.9
-8.6
cyclic pyranopterin monophosphate synthase MoaC
compare
MMP
_RS06400
-3.8
-3.5
4Fe-4S binding protein
compare
MMP
_RS01985
-3.7
-12.7
F420-dependent methylenetetrahydromethanopterin dehydrogenase
compare
MMP
_RS06715
-3.4
-20.9
cache domain-containing protein
compare
MMP
_RS08720
-3.4
-3.6
4Fe-4S binding protein
compare
MMP
_RS01385
-3.3
-1.3
imidazole glycerol phosphate synthase subunit HisH
compare
MMP
_RS02280
-3.3
-1.9
DUF211 domain-containing protein
compare
MMP
_RS06720
-3.3
-14.0
response regulator transcription factor
compare
MMP
_RS00305
-3.3
-3.2
phosphoribosyl-ATP diphosphatase
compare
MMP
_RS08820
-3.2
-9.0
hypothetical protein
compare
MMP
_RS06975
-3.0
-4.0
sulfide-dependent adenosine diphosphate thiazole synthase
compare
MMP
_RS03600
-3.0
-3.9
triose-phosphate isomerase
compare
MMP
_RS01005
-2.9
-2.5
riboflavin synthase
compare
MMP
_RS00300
-2.9
-1.6
6 7-dimethyl-8-ribityllumazine synthase
compare
MMP
_RS04775
-2.9
-6.6
adenosylhomocysteinase
compare
MMP
_RS04605
-2.8
-7.7
cobalt ECF transporter T component CbiQ
compare
MMP
_RS08745
-2.8
-9.7
CDP-2 3-bis-(O-geranylgeranyl)-sn-glycerol synthase
compare
MMP
_RS04585
-2.8
-13.9
AIR synthase related protein
compare
MMP
_RS03435
-2.7
-2.7
ketol-acid reductoisomerase
compare
MMP
_RS00895
-2.7
-7.5
hypothetical protein
compare
MMP
_RS02340
-2.7
-4.2
DNA-directed RNA polymerase subunit E''
compare
MMP
_RS06295
-2.6
-9.2
methanogenesis marker 14 protein
compare
MMP
_RS00040
-2.6
-4.6
TIGR03576 family pyridoxal phosphate-dependent enzyme
compare
MMP
_RS08460
-2.6
-4.5
proteasome-activating nucleotidase
compare
MMP
_RS07525
-2.5
-10.7
4Fe-4S binding protein
compare
MMP
_RS07445
-2.5
-7.0
helix-turn-helix domain-containing protein
compare
MMP
_RS06705
-2.5
-11.2
formate/nitrite transporter family protein
compare
MMP
_RS01500
-2.5
-5.2
CBS domain-containing protein
compare
MMP
_RS04900
-2.5
-20.3
hypothetical protein
compare
MMP
_RS03025
-2.5
-7.8
molybdenum cofactor guanylyltransferase
compare
MMP
_RS02195
-2.4
-4.1
tRNA (N(6)-L-threonylcarbamoyladenosine(37)-C(2))-methylthiotransferase
compare
MMP
_RS07845
-2.4
-5.1
LL-diaminopimelate aminotransferase
compare
MMP
_RS06285
-2.4
-4.2
precorrin-6Y C5 15-methyltransferase (decarboxylating) subunit CbiT
compare
MMP
_RS01220
-2.4
-10.9
hypothetical protein
compare
MMP
_RS08645
-2.3
-10.2
UPF0179 family protein
compare
MMP
_RS00685
-2.3
-6.0
2-phospho-L-lactate guanylyltransferase
compare
MMP
_RS08715
-2.3
-3.3
formylmethanofuran dehydrogenase subunit B
compare
MMP
_RS08210
-2.3
-4.3
phosphatidylglycerophosphatase A
compare
MMP
_RS01980
-2.3
-13.8
trimeric intracellular cation channel family protein
compare
MMP
_RS00115
-2.3
-13.8
radical SAM protein
compare
MMP
_RS07730
-2.3
-2.9
pyruvate synthase subunit beta
compare
MMP
_RS06925
-2.2
-3.6
ribonuclease VapC4
compare
MMP
_RS04615
-2.2
-8.0
PDGLE domain-containing protein
compare
MMP
_RS07545
-2.2
-1.6
HTH domain-containing protein
compare
MMP
_RS08300
-2.2
-2.0
metal-sulfur cluster assembly factor
compare
MMP
_RS06625
-2.2
-2.9
DNA primase
compare
MMP
_RS02355
-2.1
-3.9
30S ribosomal protein S27ae
compare
MMP
_RS04620
-2.1
-12.0
cobalt transporter CbiM
compare
MMP
_RS01325
-2.1
-2.4
dihydroneopterin aldolase family protein
compare
MMP
_RS06630
-2.1
-1.9
UPF0058 family protein
compare
MMP
_RS00295
-2.0
-2.9
gamma carbonic anhydrase family protein
compare
MMP
_RS01755
-2.0
-2.3
DUF2097 domain-containing protein
compare
MMP
_RS02800
-2.0
-6.3
nucleotidyltransferase domain-containing protein
compare
MMP
_RS01545
-2.0
-1.9
CBS domain-containing protein
compare
MMP
_RS01265
-2.0
-3.9
hypothetical protein
compare
MMP
_RS04890
-2.0
-1.7
adenylyltransferase/cytidyltransferase family protein
compare
MMP
_RS07755
-1.9
-2.3
DUF555 domain-containing protein
compare
MMP
_RS07005
-1.9
-1.1
4Fe-4S binding protein
compare
MMP
_RS00110
-1.9
-4.2
hypothetical protein
compare
MMP
_RS00695
-1.9
-1.5
biotin--[acetyl-CoA-carboxylase] ligase
compare
MMP
_RS07600
-1.9
-4.5
Ni-sirohydrochlorin a c-diamide synthase
compare
MMP
_RS07380
-1.9
-2.9
transcription elongation factor Spt5
compare
MMP
_RS04780
-1.9
-3.9
ribonuclease P
compare
MMP
_RS06175
-1.9
-9.1
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS06105
-1.8
-8.5
hydrogenase maturation peptidase HycI
compare
MMP
_RS07735
-1.8
-1.8
2-ketoisovalerate ferredoxin oxidoreductase subunit alpha
compare
MMP
_RS06475
-1.8
-5.8
FAD-dependent oxidoreductase
compare
MMP
_RS05765
-1.8
-6.5
M42 family metallopeptidase
compare
MMP
_RS07605
-1.7
-3.8
diadenylate cyclase
compare
MMP
_RS01225
-1.7
-4.4
DUF5379 domain-containing protein
compare
MMP
_RS02165
-1.7
-8.1
tRNA-dihydrouridine synthase
compare
MMP
_RS01795
-1.7
-2.7
methanogenesis marker 6 protein
compare
MMP
_RS07765
-1.7
-8.9
sodium:alanine symporter family protein
compare
MMP
_RS03640
-1.7
-5.0
archaeal proteasome endopeptidase complex subunit beta
compare
MMP
_RS02240
-1.7
-4.3
methanogenesis marker 7 protein
compare
MMP
_RS01800
-1.7
-4.3
TIGR00303 family protein
compare
MMP
_RS06930
-1.6
-10.3
MBL fold metallo-hydrolase
compare
MMP
_RS04500
-1.6
-11.7
adenosylmethionine--8-amino-7-oxononanoate transaminase
compare
MMP
_RS06020
-1.6
-4.6
archaeoflavoprotein AfpA
compare
MMP
_RS05540
-1.6
-3.5
hypothetical protein
compare
MMP
_RS05430
-1.6
-5.3
TIGR00288 family NYN domain-containing protein
compare
MMP
_RS06200
-1.6
-9.0
M24 family metallopeptidase
compare
MMP
_RS09020
-1.5
-2.5
hypothetical protein
compare
MMP
_RS06120
-1.5
-2.9
UPF0147 family protein
compare
MMP
_RS06370
-1.5
-5.1
biotin synthase BioB
compare
MMP
_RS03580
-1.5
-5.0
signal recognition particle-docking protein FtsY
compare
MMP
_RS00620
-1.5
-8.0
4Fe-4S binding protein
compare
MMP
_RS06730
-1.5
-2.0
phosphopantothenate/pantothenate synthetase
compare
MMP
_RS06885
-1.5
-2.3
50S ribosome-binding GTPase
compare
MMP
_RS08100
-1.4
-6.0
8-amino-7-oxononanoate synthase
compare
MMP
_RS06315
-1.4
-1.6
cobalt-precorrin-7 (C(5))-methyltransferase
compare
MMP
_RS02190
-1.4
-3.3
sulfopyruvate decarboxylase subunit alpha
compare
MMP
_RS05510
-1.4
-3.6
Rrf2 family transcriptional regulator
compare
MMP
_RS07575
-1.4
-6.2
RNA ligase partner protein
compare
MMP
_RS07365
-1.4
-9.6
2-phosphoglycerate kinase
compare
MMP
_RS06230
-1.4
-3.3
helix-turn-helix domain-containing protein
compare
MMP
_RS02135
-1.3
-4.6
DUF5612 domain-containing protein
compare
MMP
_RS06270
-1.3
-5.4
TIGR00300 family protein
compare
MMP
_RS02235
-1.3
-6.6
CBS domain-containing protein
compare
MMP
_RS01610
-1.3
-3.7
hypothetical protein
compare
MMP
_RS02900
-1.3
-0.8
imidazoleglycerol-phosphate dehydratase HisB
compare
MMP
_RS08095
-1.3
-5.8
dethiobiotin synthase
compare
MMP
_RS06215
-1.3
-4.2
30S ribosomal protein S6e
compare
MMP
_RS01830
-1.3
-1.8
tRNA-Val
compare
MMP
_RS05245
-1.3
-8.1
archaeosine biosynthesis radical SAM protein RaSEA
compare
MMP
_RS03445
-1.3
-1.4
methanogenesis marker 17 protein
compare
MMP
_RS01380
-1.3
-4.2
PHP domain-containing protein
compare
MMP
_RS05875
-1.3
-6.2
hydroxyethylthiazole kinase
compare
MMP
_RS05815
-1.3
-1.8
NOL1/NOP2/sun family putative RNA methylase
compare
MMP
_RS08790
-1.2
-2.9
translation initiation factor IF-2 subunit alpha
compare
MMP
_RS01700
-1.2
-1.3
dihydroxy-acid dehydratase
compare
MMP
_RS07630
-1.2
-2.1
ATP-binding cassette domain-containing protein
compare
MMP
_RS05920
-1.2
-0.8
50S ribosomal protein L37e
compare
MMP
_RS06865
-1.1
-1.3
HypC/HybG/HupF family hydrogenase formation chaperone
compare
MMP
_RS07200
-1.1
-5.1
[5-(aminomethyl)furan-3-yl]methyl phosphate kinase
compare
MMP
_RS04870
-1.1
-5.1
TIGR02253 family HAD-type hydrolase
compare
MMP
_RS03035
-1.1
-2.5
4-hydroxy-tetrahydrodipicolinate synthase
compare
MMP
_RS05500
-1.1
-6.5
2-isopropylmalate synthase
compare
MMP
_RS07685
-1.1
-5.5
TIGR01212 family radical SAM protein
compare
MMP
_RS06340
-1.1
-5.9
phosphoadenosine phosphosulfate reductase family protein
compare
MMP
_RS03485
-1.1
-2.9
TIGR00267 family protein
compare
MMP
_RS08105
-1.1
-6.3
6-carboxyhexanoate--CoA ligase
compare
MMP
_RS00050
-1.0
-6.5
AarF/UbiB family protein
compare
MMP
_RS06915
-1.0
-4.6
metallophosphoesterase
compare
MMP
_RS00555
-1.0
-3.3
MFS transporter
compare
MMP
_RS03400
-1.0
-2.1
archease
compare
MMP
_RS08650
-1.0
-3.0
glutamine--fructose-6-phosphate transaminase (isomerizing)
compare
MMP
_RS00290
-1.0
-4.9
hypothetical protein
compare
MMP
_RS05545
-1.0
-5.3
pyridoxal phosphate-dependent aminotransferase
compare
MMP
_RS08635
-1.0
-1.8
UbiA family prenyltransferase
compare
MMP
_RS03590
-1.0
-5.0
METTL5 family protein
compare
MMP
_RS03250
-1.0
-2.8
MJ1244 family protein
compare
MMP
_RS00520
-1.0
-1.6
RNA polymerase Rpb4 family protein
compare
MMP
_RS02145
-1.0
-4.5
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS03960
-1.0
-1.2
hypothetical protein
compare
MMP
_RS08435
-1.0
-1.5
Era-like GTP-binding protein
compare
MMP
_RS01250
-0.9
-3.6
tRNA (guanine(26)-N(2))-dimethyltransferase
compare
MMP
_RS05345
-0.9
-4.1
hypothetical protein
compare
MMP
_RS05845
-0.9
-1.2
tRNA-intron lyase
compare
MMP
_RS01365
-0.9
-4.2
archaeal proteasome endopeptidase complex subunit alpha
compare
MMP
_RS08200
-0.9
-7.2
archaeosine synthase subunit alpha
compare
MMP
_RS00515
-0.9
-0.6
DUF655 domain-containing protein
compare
MMP
_RS00850
-0.9
-3.7
TIGR01177 family methyltransferase
compare
MMP
_RS06130
-0.9
-2.4
peptidylprolyl isomerase
compare
MMP
_RS07195
-0.9
-6.3
M20 family metallo-hydrolase
compare
MMP
_RS04710
-0.9
-1.3
hypothetical protein
compare
MMP
_RS00720
-0.9
-4.9
metal-dependent hydrolase
compare
MMP
_RS08165
-0.8
-2.2
phosphoglycerate dehydrogenase
compare
MMP
_RS07645
-0.8
-3.4
aldehyde dehydrogenase family protein
compare
MMP
_RS08615
-0.8
-2.3
flagellar protein G
compare
MMP
_RS03095
-0.8
-5.1
diphthine synthase
compare
MMP
_RS01725
-0.8
-3.6
class I SAM-dependent methyltransferase family protein
compare
MMP
_RS02345
-0.8
-1.9
GTP-dependent dephospho-CoA kinase family protein
compare
MMP
_RS07750
-0.8
-2.5
DUF357 domain-containing protein
compare
MMP
_RS00035
-0.8
-4.8
DUF2098 family protein
compare
MMP
_RS08445
-0.8
-3.2
DUF2099 family protein
compare
MMP
_RS05250
-0.8
-1.4
NFYB/HAP3 family transcription factor subunit
compare
MMP
_RS02245
-0.8
-2.8
hypothetical protein
compare
MMP
_RS07775
-0.8
-3.5
alanine dehydrogenase
compare
MMP
_RS08940
-0.7
-1.3
MetS family NSS transporter small subunit
compare
MMP
_RS03155
-0.7
-3.9
precorrin-6A reductase
compare
MMP
_RS08915
-0.7
-1.6
2 5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase
compare
MMP
_RS01840
-0.7
-4.3
TIGR00289 family protein
compare
MMP
_RS01180
-0.7
-1.1
XTP/dITP diphosphatase
compare
MMP
_RS08240
-0.7
-2.5
methanogenesis marker 16 metalloprotein
compare
MMP
_RS08690
-0.7
-3.5
RNA-guided pseudouridylation complex pseudouridine synthase subunit Cbf5
compare
MMP
_RS06870
-0.7
-3.1
DedA family protein
compare
MMP
_RS01075
-0.7
-1.9
hypothetical protein
compare
MMP
_RS06980
-0.7
-4.1
tRNA 2-thiocytidine biosynthesis TtcA family protein
compare
MMP
_RS05440
-0.7
-4.7
winged helix-turn-helix transcriptional regulator
compare
MMP
_RS01890
-0.7
-3.1
nucleotide sugar dehydrogenase
compare
MMP
_RS01600
-0.7
-1.1
50S ribosomal protein L15e
compare
MMP
_RS00710
-0.7
-2.1
hypothetical protein
compare
MMP
_RS04695
-0.7
-2.8
selenide water dikinase SelD
compare
MMP
_RS06920
-0.7
-5.2
AAA family ATPase
compare
MMP
_RS04685
-0.7
-1.3
DUF126 domain-containing protein
compare
MMP
_RS05800
-0.7
-4.4
B12-binding domain-containing radical SAM protein
compare
MMP
_RS07180
-0.7
-3.3
DEAD/DEAH box helicase
compare
MMP
_RS03305
-0.7
-3.9
winged helix-turn-helix domain-containing protein
compare
MMP
_RS02170
-0.7
-2.6
CBS domain-containing protein
compare
MMP
_RS07710
-0.7
-2.8
cell division protein FtsZ
compare
MMP
_RS00915
-0.6
-3.6
DUF116 domain-containing protein
compare
MMP
_RS05550
-0.6
-0.6
cation:proton antiporter
compare
MMP
_RS07790
-0.6
-3.3
segregation/condensation protein A
compare
MMP
_RS08320
-0.6
-3.6
molybdopterin molybdotransferase MoeA
compare
MMP
_RS05315
-0.6
-1.5
hypothetical protein
compare
MMP
_RS07425
-0.6
-2.7
GTP-binding protein
compare
MMP
_RS05835
-0.6
-0.6
secondary thiamine-phosphate synthase enzyme YjbQ
compare
Specific Phenotypes
None in this experiment
For Methanococcus maripaludis S2 in nutrient t1 experiments