Experiment set6IT008 for Phaeobacter inhibens DSM 17395

Compare to:

marine broth with Cisplatin 0.025 mg/ml

200 most detrimental genes:

  gene name fitness t score description  
PGA1_c18600 +1.9 9.5 hypothetical protein compare
PGA1_c08590 +1.7 11.7 heme NO binding domain-containing protein compare
PGA1_c11540 +1.5 2.0 gamma-glutamylputrescine synthetase PuuA compare
PGA1_c08600 +1.5 10.2 diguanylate cyclase (GGDEF) domain-containing protein compare
PGA1_c34480 +1.4 4.6 UTP--glucose-1-phosphate uridylyltransferase CelA compare
PGA1_c34880 +1.3 10.2 putative response regulator compare
PGA1_c33190 +1.3 5.5 putative anti-sigma-B factor antagonist compare
PGA1_c34890 +1.3 9.0 putative histidine-containing phosphotransfer protein compare
PGA1_c35920 +1.2 2.3 thiamine kinase ThiK-like protein compare
PGA1_c20140 +1.2 5.7 putative arginine-tRNA-protein transferase compare
PGA1_c07860 +1.2 8.0 alpha-glucosides-binding periplasmic protein AglE compare
PGA1_c26780 +1.2 2.7 cold shock protein CspA compare
PGA1_c07890 +1.2 8.2 cytoplasmic trehalase (AlgA) (from data) compare
PGA1_c14140 +1.2 2.5 hypothetical protein compare
PGA1_c12310 +1.1 8.3 glucans biosynthesis protein G compare
PGA1_c23800 +1.1 7.0 hypothetical protein compare
PGA1_c07900 +1.1 7.2 alpha-glucoside transport ATP-binding protein AglK compare
PGA1_c07880 +1.1 6.8 alpha-glucoside transport system permease protein AglG compare
PGA1_c06280 +1.1 1.6 cytochrome c oxidase assembly protein CtaG compare
PGA1_c16070 +1.0 3.5 guanosine-5'-triphosphate,3'-diphosphate pyrophosphatase-like protein compare
PGA1_c18560 +1.0 2.3 hypothetical protein compare
PGA1_c17050 +1.0 2.5 N-acetyl-gamma-glutamyl-phosphate reductase ArgC compare
PGA1_c14700 +1.0 2.7 hypothetical protein compare
PGA1_c27660 +1.0 3.2 hypothetical protein compare
PGA1_c19200 +1.0 2.3 Predicted Fe-S protein compare
PGA1_c11470 +1.0 4.2 acetyltransferase domain-containing protein compare
PGA1_262p00930 +1.0 3.3 hypothetical protein compare
PGA1_c07870 +1.0 4.8 alpha-glucoside transport system permease protein AglF compare
PGA1_c29060 +0.9 2.4 HTH-type transcriptional regulator PecS compare
PGA1_c12300 +0.9 6.1 glucans biosynthesis glucosyltransferase H compare
PGA1_c30580 +0.9 2.4 TIGR02300 family protein compare
PGA1_c10730 +0.9 2.3 ribose-5-phosphate isomerase B compare
PGA1_c05560 +0.9 2.7 glycine cleavage system protein GcvH compare
PGA1_65p00070 +0.9 2.0 putative regulatory protein, LuxR family compare
PGA1_c18390 +0.9 1.6 hypothetical protein compare
PGA1_c18380 +0.9 1.4 Phage Head-Tail Attachment. compare
PGA1_c10200 +0.8 0.7 molybdenum cofactor biosynthesis protein A compare
PGA1_c15660 +0.8 2.7 enoyl-CoA hydratase/isomerase family protein compare
PGA1_c14190 +0.8 4.4 putative transcriptional regulator, AraC family compare
PGA1_c26300 +0.8 2.2 ABC transporter, ATP-binding protein compare
PGA1_c05390 +0.8 4.2 glycosyl transferase compare
PGA1_c12320 +0.8 4.1 Uncharacterized protein conserved in bacteria compare
PGA1_c19910 +0.8 1.8 Protein of unknown function (DUF1499). compare
PGA1_c23540 +0.8 4.3 O-succinylhomoserine sulfhydrylase MetZ compare
PGA1_c24180 +0.8 2.9 LAO/AO transport system kinase ArgK compare
PGA1_c19090 +0.8 1.5 Protein required for attachment to host cells compare
PGA1_c02450 +0.8 6.0 putative outer membrane efflux protein compare
PGA1_c21260 +0.8 2.6 hypothetical protein compare
PGA1_c00610 +0.8 1.3 acetyltransferase, GNAT family compare
PGA1_c02430 +0.8 5.3 type I secretion membrane fusion protein, HlyD family compare
PGA1_262p01110 +0.8 2.5 hypothetical protein compare
PGA1_262p01390 +0.8 2.4 hypothetical protein compare
PGA1_c34120 +0.8 1.5 HTH-type transcriptional regulator PetP compare
PGA1_262p00700 +0.7 1.2 stressosome protein rsbS-like protein compare
PGA1_c24310 +0.7 3.3 putative capsular polysaccharide transport system, ATP-binding protein compare
PGA1_c32110 +0.7 2.7 hypothetical protein compare
PGA1_c31260 +0.7 6.5 Protein of unknown function (DUF3131). compare
PGA1_c21580 +0.7 2.6 hypothetical protein compare
PGA1_c02460 +0.7 5.8 hypothetical protein compare
PGA1_c16120 +0.7 2.1 hypothetical protein compare
PGA1_c00680 +0.7 1.8 transcriptional regulator, arsR family compare
PGA1_c22830 +0.7 2.2 putative type IV secretion system protein VirB2 compare
PGA1_c12070 +0.7 1.3 hypothetical protein compare
PGA1_c02440 +0.7 5.2 putative ATP-binding/permease fusion ABC transporter compare
PGA1_c33170 +0.7 3.0 putative sensor protein compare
PGA1_c12110 +0.7 2.1 thioesterase domain-containing protein compare
PGA1_78p00490 +0.7 1.0 putative HTH-type transcriptional regulator compare
PGA1_c01150 +0.7 5.3 transcriptional regulatory protein ChvI compare
PGA1_c35020 +0.7 3.3 heat-inducible transcription repressor HrcA compare
PGA1_c31270 +0.7 6.0 putative glycosyltransferase / polysaccharide deacetylase compare
PGA1_c15590 +0.7 5.9 putative transcriptional activator protein compare
PGA1_c23720 +0.7 1.7 glutathione reductase Gor compare
PGA1_c15330 +0.7 2.3 hypothetical protein compare
PGA1_262p01410 +0.7 1.5 malate/L-lactate dehydrogenase-like protein compare
PGA1_262p00060 +0.7 1.7 putative glycosyl transferase compare
PGA1_262p00660 +0.7 1.9 Predicted periplasmic protein compare
PGA1_c12550 +0.7 1.7 hypothetical protein compare
PGA1_c19140 +0.7 2.9 sarcosine oxidase-like protein compare
PGA1_c06370 +0.7 1.5 adenine phosphoribosyltransferase Apt compare
PGA1_c11220 +0.6 4.7 Predicted transcriptional regulators compare
PGA1_c22070 +0.6 2.9 Cytochrome B561 compare
PGA1_262p01270 +0.6 1.8 Uncharacterized conserved protein compare
PGA1_c01160 +0.6 4.9 sensor protein ChvG compare
PGA1_262p01250 +0.6 1.1 transcriptional regulator, crp family compare
PGA1_c23470 +0.6 1.4 transcriptional regulator, MarR family compare
PGA1_262p01600 +0.6 1.4 putative ABC transporter, ATP binding protein compare
PGA1_c06980 +0.6 0.8 hypothetical protein compare
PGA1_c19790 +0.6 1.7 putative DNA polymerase III chi subunit, holC compare
PGA1_c00950 +0.6 3.3 Protein of unknown function (DUF3429). compare
PGA1_c11970 +0.6 3.4 Sporulation related domain. compare
PGA1_c01260 +0.6 1.1 putative cobalamin adenosyltransferase compare
PGA1_c05350 +0.6 4.7 dimodular nonribosomal peptide synthetase compare
PGA1_c29900 +0.6 1.3 protein slyX-like protein compare
PGA1_c26480 +0.6 2.2 Protein involved in catabolism of external DNA compare
PGA1_c11710 +0.6 2.3 transcriptional regulator, LysR family compare
PGA1_c33590 +0.6 2.6 hypothetical protein compare
PGA1_c20910 +0.6 2.2 PHA synthesis repressor protein PhaR compare
PGA1_c19680 +0.5 1.6 putative transcriptional regulator, crp family compare
PGA1_c00600 +0.5 0.9 putative acetyltransferase compare
PGA1_c13110 +0.5 1.7 putative nitrilotriacetate monooxygenase component B compare
PGA1_c23770 +0.5 3.1 L-serine dehydratase TdcG compare
PGA1_c06400 +0.5 1.1 putative antibiotic acetyltransferase compare
PGA1_c15380 +0.5 0.6 Uncharacterized conserved protein compare
PGA1_c05360 +0.5 3.2 putative glycosyl transferase compare
PGA1_c22860 +0.5 1.1 hypothetical protein compare
PGA1_c06020 +0.5 2.0 thioesterase domain-containing protein compare
PGA1_c08890 +0.5 2.2 putative capsule polysaccharide export outer membrane protein compare
PGA1_c07650 +0.5 3.8 hypothetical protein compare
PGA1_c15060 +0.5 2.1 carbohydrate kinase, PfkB family compare
PGA1_c31880 +0.5 4.6 signal transduction histidine kinase compare
PGA1_c05370 +0.5 4.7 polyketide synthase compare
PGA1_262p00370 +0.5 2.3 putative polysaccharide synthase compare
PGA1_c28420 +0.5 2.7 putative D,D-dipeptide transport system permease protein compare
PGA1_c01960 +0.5 1.3 putative hydrolase compare
PGA1_c18500 +0.5 2.4 hypothetical protein compare
PGA1_c19160 +0.5 2.3 sarcosine oxidase 2 subunit delta compare
PGA1_262p00040 +0.5 1.7 sulfotransferase-like protein compare
PGA1_c33055 +0.5 1.7 hypothetical protein compare
PGA1_c33660 +0.5 2.2 hypothetical protein compare
PGA1_c34520 +0.5 3.2 alpha-ketoglutarate-dependent dioxygenase AlkB compare
PGA1_262p00950 +0.5 1.4 thioesterase superfamily protein TdaD compare
PGA1_c19800 +0.5 2.2 cytosol aminopeptidase PepA compare
PGA1_c34650 +0.5 0.8 UPF0090 protein YhbC compare
PGA1_c02230 +0.5 2.4 hypothetical protein compare
PGA1_262p02160 +0.5 2.5 putative chemotaxis response regulator protein-glutamate methylesterase compare
PGA1_65p00160 +0.5 2.0 Bacterial putative lipoprotein (DUF940). compare
PGA1_c12330 +0.5 2.2 hypothetical protein compare
PGA1_c05400 +0.5 2.9 putative glycosyl transferase, family 2 compare
PGA1_c16010 +0.5 2.4 putative L,D-transpeptidase compare
PGA1_262p00250 +0.5 1.4 ferritin-like protein compare
PGA1_c17410 +0.5 2.6 MFS type transporter compare
PGA1_c16870 +0.5 2.3 Uncharacterized protein conserved in bacteria compare
PGA1_c13510 +0.5 1.2 hypothetical protein compare
PGA1_c04950 +0.5 0.9 GTP-dependent nucleic acid-binding protein EngD compare
PGA1_c10020 +0.5 1.4 Putative protein-S-isoprenylcysteine methyltransferase compare
PGA1_c09140 +0.5 2.0 dethiobiotin synthetase BioD compare
PGA1_c01670 +0.5 1.7 hypothetical protein compare
PGA1_c05690 +0.5 1.7 Truncated hemoglobins compare
PGA1_c11830 +0.5 1.2 hypothetical protein compare
PGA1_262p02180 +0.5 1.9 molybdate-binding periplasmic protein ModA compare
PGA1_262p00200 +0.5 1.8 transcriptional regulator, LysR family compare
PGA1_c24410 +0.5 1.1 hypothetical protein compare
PGA1_c24690 +0.5 2.4 protein CsaA-like protein compare
PGA1_c15810 +0.5 2.4 pyridoxal phosphate-dependent enzyme, cysteine / methionine metabolism compare
PGA1_c30000 +0.5 1.0 ATP-dependent Clp protease adaptor protein ClpS compare
PGA1_262p01060 +0.5 0.8 Protein of unknown function (DUF995). compare
PGA1_c02030 +0.5 0.7 phosphoglycerate mutase-like protein compare
PGA1_c02550 +0.5 2.3 protocatechuate 3,4-dioxygenase alpha chain compare
PGA1_c08370 +0.5 1.9 Rhodanese-related sulfurtransferase compare
PGA1_c10920 +0.5 2.4 hypothetical protein compare
PGA1_262p01700 +0.5 1.8 putative ABC transporter, solute-binding protein compare
PGA1_c17660 +0.4 1.6 hypothetical protein compare
PGA1_c33060 +0.4 1.7 glyoxalase-like protein compare
PGA1_c05380 +0.4 2.7 hypothetical protein compare
PGA1_c11690 +0.4 2.4 thioesterase domain-containing protein compare
PGA1_c00170 +0.4 2.1 hypothetical protein compare
PGA1_c25950 +0.4 1.5 putative biopolymer transport protein compare
PGA1_c21060 +0.4 1.5 cold shock protein CspA compare
PGA1_c22500 +0.4 1.1 hypothetical protein compare
PGA1_c21210 +0.4 1.3 putative lactoylglutathione lyase compare
PGA1_c05280 +0.4 2.5 hypothetical protein compare
PGA1_c24810 +0.4 2.1 Glycosyltransferase family 10 (fucosyltransferase). compare
PGA1_262p00870 +0.4 1.5 ABC transporter, extracellular solute-binding protein compare
PGA1_c15200 +0.4 1.0 ATP-dependent reduction of co(II)balamin (RamA-like) (EC:2.1.1.13) (from data) compare
PGA1_c06460 +0.4 2.9 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain compare
PGA1_c32900 +0.4 1.7 Antibiotic biosynthesis monooxygenase. compare
PGA1_c32590 +0.4 1.3 hypothetical protein compare
PGA1_c26980 +0.4 1.4 Rho termination factor, N-terminal domain. compare
PGA1_c27130 +0.4 2.8 putative HTH-type transcriptional regulator compare
PGA1_c24250 +0.4 1.8 inner membrane transport permease compare
PGA1_c07270 +0.4 1.8 Myo-inosose-2 dehydratase (EC 4.2.1.44) (from data) compare
PGA1_c22840 +0.4 2.0 putative type IV secretory pathway virB3 protein compare
PGA1_c05300 +0.4 2.4 putative glycosyl transferase compare
PGA1_c12940 +0.4 1.3 adenylate kinase Adk compare
PGA1_c04960 +0.4 2.5 putative non-specific ribonucleoside hydrolase compare
PGA1_c11190 +0.4 0.6 hypothetical protein compare
PGA1_c14550 +0.4 2.4 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) compare
PGA1_c09160 +0.4 1.9 Uncharacterized protein conserved in bacteria compare
PGA1_c05260 +0.4 3.0 exopolysaccharide production protein ExoY-like protein compare
PGA1_c13530 +0.4 2.0 hypothetical protein compare
PGA1_c15020 +0.4 2.1 D-beta-hydroxybutyrate dehydrogenase BdhA compare
PGA1_c13060 +0.4 0.9 sensor histidine kinase compare
PGA1_c07160 +0.4 2.4 FOG: WD40 repeat compare
PGA1_c15610 +0.4 2.1 alcohol dehydrogenase, zinc binding compare
PGA1_c22480 +0.4 1.8 hypothetical protein compare
PGA1_c06150 +0.4 2.3 Flp pilus assembly protein CpaB-like protein compare
PGA1_c01100 +0.4 1.0 Heat shock protein compare
PGA1_c16680 +0.4 2.0 sugar ABC transporter, ATP-binding protein compare
PGA1_c11550 +0.4 1.9 putative histidine transport system permease protein compare
PGA1_c26030 +0.4 0.6 transcriptional regulator, MarR family compare
PGA1_262p01780 +0.4 1.0 transcriptional regulator, LysR family compare
PGA1_c16110 +0.4 1.0 putative ion channel compare
PGA1_c11760 +0.4 1.2 putative proline dehydrogenase transcriptional activator compare
PGA1_c21720 +0.4 2.0 putative S-adenosylmethionine uptake transporter compare
PGA1_c18580 +0.4 1.1 hypothetical protein compare
PGA1_c05290 +0.4 2.6 polysaccharide biosynthesis protein ExoT-like protein compare
PGA1_c05620 +0.4 1.7 putative 7-cyano-7-deazaguanosine biosynthesis protein QueE compare
PGA1_c00400 +0.4 1.5 Protein of unknown function (DUF2783). compare
PGA1_262p00100 +0.4 2.1 putative glycosyl transferase compare
PGA1_c10270 +0.4 2.4 hypothetical protein compare


Specific Phenotypes

For 15 genes in this experiment

For stress Cisplatin in Phaeobacter inhibens DSM 17395

For stress Cisplatin across organisms